CY1113298T1 - Ανασυνδυασμενα αντισωματα υψηλης ισχυος και μεθοδος παραγωγης αυτων - Google Patents
Ανασυνδυασμενα αντισωματα υψηλης ισχυος και μεθοδος παραγωγης αυτωνInfo
- Publication number
- CY1113298T1 CY1113298T1 CY20121100934T CY121100934T CY1113298T1 CY 1113298 T1 CY1113298 T1 CY 1113298T1 CY 20121100934 T CY20121100934 T CY 20121100934T CY 121100934 T CY121100934 T CY 121100934T CY 1113298 T1 CY1113298 T1 CY 1113298T1
- Authority
- CY
- Cyprus
- Prior art keywords
- antibodies
- neutralizing
- producing
- disclosed
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000011084 recovery Methods 0.000 title 1
- 230000003472 neutralizing effect Effects 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003053 toxin Substances 0.000 abstract 2
- 231100000765 toxin Toxicity 0.000 abstract 2
- 108700012359 toxins Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18625200P | 2000-03-01 | 2000-03-01 | |
| EP01914657A EP1259547B1 (en) | 2000-03-01 | 2001-03-01 | High potency recombinant antibodies and method for producing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1113298T1 true CY1113298T1 (el) | 2016-04-13 |
Family
ID=22684221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100934T CY1113298T1 (el) | 2000-03-01 | 2012-10-05 | Ανασυνδυασμενα αντισωματα υψηλης ισχυος και μεθοδος παραγωγης αυτων |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7700735B2 (enExample) |
| EP (3) | EP1259547B1 (enExample) |
| JP (2) | JP2003525061A (enExample) |
| AU (4) | AU2001240020B9 (enExample) |
| CA (1) | CA2401652A1 (enExample) |
| CY (1) | CY1113298T1 (enExample) |
| DK (1) | DK1259547T3 (enExample) |
| ES (1) | ES2390761T3 (enExample) |
| PT (1) | PT1259547E (enExample) |
| WO (1) | WO2001064751A2 (enExample) |
Families Citing this family (50)
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|---|---|---|---|---|
| DK1265928T3 (da) * | 2000-01-27 | 2010-11-15 | Medimmune Llc | RSV-neutraliserende antistoffer med ultra høj affinitet |
| WO2001064751A2 (en) * | 2000-03-01 | 2001-09-07 | Medimmune, Inc. | High potency recombinant antibodies and method for producing them |
| US7229619B1 (en) | 2000-11-28 | 2007-06-12 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| US6855493B2 (en) * | 2000-11-28 | 2005-02-15 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| US7179900B2 (en) | 2000-11-28 | 2007-02-20 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| JP4434580B2 (ja) * | 2000-11-28 | 2010-03-17 | メディミューン,エルエルシー | 予防及び治療のために抗rsv抗体を投与/処方する方法 |
| PT1355919E (pt) * | 2000-12-12 | 2011-03-02 | Medimmune Llc | Moléculas com semivida longa, composições que as contêm e suas utilizações |
| MXPA04004224A (es) * | 2001-11-02 | 2005-03-31 | Johnson & Johnson | Proteinas del virus sincitial respiratorio, anticuerpos, composiciones, metodos y usos. |
| EP2075256A2 (en) | 2002-01-14 | 2009-07-01 | William Herman | Multispecific binding molecules |
| AU2003217386B2 (en) * | 2002-02-13 | 2008-06-26 | Ludwig Institute For Cancer Research | Humanized GM-CSF antibodies |
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| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) * | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| TW200501985A (en) * | 2002-07-25 | 2005-01-16 | Medimmune Inc | Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies |
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| AU2005302453A1 (en) * | 2004-10-29 | 2006-05-11 | Medimmune, Llc | Methods of preventing and treating RSV infections and related conditions |
| AU2007222798A1 (en) * | 2006-03-06 | 2007-09-13 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| WO2008070042A2 (en) * | 2006-12-04 | 2008-06-12 | Medimmune, Inc. | High potency recombinant antibodies, methods for producing them and use in cancer therapy |
| BRPI0808673A2 (pt) * | 2007-03-06 | 2014-08-12 | Symphogen As | Anticorpos recombinantes para tratamento de infecções com vírus sinciciais respiratórios. |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| JP2010531878A (ja) | 2007-06-27 | 2010-09-30 | マリン ポリマー テクノロジーズ,インコーポレーテッド | IL‐15とIL‐15Rαとの複合体及びその使用 |
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| WO2010068722A1 (en) | 2008-12-12 | 2010-06-17 | Medimmune, Llc | Crystals and structure of a human igg fc variant with enhanced fcrn binding |
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| WO2010087927A2 (en) | 2009-02-02 | 2010-08-05 | Medimmune, Llc | Antibodies against and methods for producing vaccines for respiratory syncytial virus |
| JP5883384B2 (ja) | 2009-08-13 | 2016-03-15 | ザ ジョンズ ホプキンス ユニバーシティー | 免疫機能を調節する方法 |
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| WO2011062560A1 (en) * | 2009-11-19 | 2011-05-26 | National University Of Singapore | Method for producing t cell receptor-like monoclonal antibodies and uses thereof |
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| HRP20200887T1 (hr) | 2011-05-04 | 2020-09-04 | Omeros Corporation | Smjese za inhibiciju masp-2 ovisne aktivacije komplementa |
| TWI692485B (zh) | 2011-05-20 | 2020-05-01 | 美商艾爾德生物控股有限責任公司 | 抗降血鈣素基因相關胜肽(anti-cgrp)組成物及其用途 |
| US9708393B2 (en) | 2011-05-20 | 2017-07-18 | Alderbio Holdings Llc | Use of anti-CGRP antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers |
| NZ717704A (en) | 2011-05-20 | 2022-08-26 | H Lundbeck As | Use of anti-cgrp or anti-cgrp-r antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea |
| TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒f蛋白質的人類抗體及其使用方法 |
| US20170114122A1 (en) | 2015-10-23 | 2017-04-27 | Alderbio Holdings Llc | Regulation of glucose metabolism using anti-cgrp antibodies |
| ES2903257T3 (es) * | 2015-12-09 | 2022-03-31 | Scripps Research Inst | Proteínas de fusión de inmunoglobulina de relaxina y métodos de uso |
| BR112019008063A2 (pt) | 2016-10-21 | 2019-07-02 | Adimab Llc | anticorpos contra o vírus sincicial anti-respiratório e métodos de sua geração e uso |
| CA3040893A1 (en) | 2016-10-21 | 2018-04-26 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| EP3529272A2 (en) | 2016-10-21 | 2019-08-28 | Adimab, LLC | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| WO2020146527A1 (en) | 2019-01-08 | 2020-07-16 | Alder Biopharmaceuticals, Inc. | Acute treatment and rapid treatment of headache using anti-cgrp antibodies |
| SG10202003296VA (en) | 2020-04-06 | 2021-11-29 | H Lundbeck As | Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies |
| WO2025104604A1 (en) | 2023-11-14 | 2025-05-22 | Janssen Pharmaceuticals, Inc. | Anti-respiratory syncytial virus antibodies and uses thereof |
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-
2001
- 2001-03-01 WO PCT/US2001/006815 patent/WO2001064751A2/en not_active Ceased
- 2001-03-01 PT PT01914657T patent/PT1259547E/pt unknown
- 2001-03-01 JP JP2001564244A patent/JP2003525061A/ja active Pending
- 2001-03-01 ES ES01914657T patent/ES2390761T3/es not_active Expired - Lifetime
- 2001-03-01 EP EP01914657A patent/EP1259547B1/en not_active Expired - Lifetime
- 2001-03-01 CA CA002401652A patent/CA2401652A1/en not_active Abandoned
- 2001-03-01 EP EP10010678A patent/EP2341075A1/en not_active Withdrawn
- 2001-03-01 US US09/796,848 patent/US7700735B2/en not_active Expired - Fee Related
- 2001-03-01 DK DK01914657.0T patent/DK1259547T3/da active
- 2001-03-01 AU AU2001240020A patent/AU2001240020B9/en not_active Ceased
- 2001-03-01 EP EP10010677A patent/EP2341074A1/en not_active Withdrawn
- 2001-03-01 AU AU4002001A patent/AU4002001A/xx active Pending
-
2007
- 2007-05-08 AU AU2007202040A patent/AU2007202040B2/en not_active Ceased
-
2010
- 2010-02-09 JP JP2010026290A patent/JP2010162025A/ja active Pending
- 2010-02-17 US US12/707,527 patent/US8153133B2/en not_active Expired - Fee Related
- 2010-09-03 AU AU2010219289A patent/AU2010219289B2/en not_active Ceased
-
2012
- 2012-10-05 CY CY20121100934T patent/CY1113298T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2390761T3 (es) | 2012-11-16 |
| AU4002001A (en) | 2001-09-12 |
| US8153133B2 (en) | 2012-04-10 |
| JP2003525061A (ja) | 2003-08-26 |
| US7700735B2 (en) | 2010-04-20 |
| EP2341074A1 (en) | 2011-07-06 |
| DK1259547T3 (da) | 2012-10-15 |
| AU2007202040A1 (en) | 2007-05-24 |
| CA2401652A1 (en) | 2001-09-07 |
| US20020098189A1 (en) | 2002-07-25 |
| AU2010219289A1 (en) | 2010-09-30 |
| AU2007202040B2 (en) | 2010-06-10 |
| EP1259547A2 (en) | 2002-11-27 |
| EP2341075A1 (en) | 2011-07-06 |
| WO2001064751A3 (en) | 2001-12-20 |
| PT1259547E (pt) | 2012-10-15 |
| AU2010219289B2 (en) | 2012-05-10 |
| AU2001240020B2 (en) | 2007-02-08 |
| US20100239574A1 (en) | 2010-09-23 |
| WO2001064751A2 (en) | 2001-09-07 |
| AU2001240020B9 (en) | 2008-12-04 |
| JP2010162025A (ja) | 2010-07-29 |
| EP1259547B1 (en) | 2012-07-11 |
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