ATE85622T1 - Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus. - Google Patents

Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.

Info

Publication number
ATE85622T1
ATE85622T1 AT88909879T AT88909879T ATE85622T1 AT E85622 T1 ATE85622 T1 AT E85622T1 AT 88909879 T AT88909879 T AT 88909879T AT 88909879 T AT88909879 T AT 88909879T AT E85622 T1 ATE85622 T1 AT E85622T1
Authority
AT
Austria
Prior art keywords
respiratory syncytial
syncytial virus
human respiratory
glycoproteins
containing immunogenic
Prior art date
Application number
AT88909879T
Other languages
English (en)
Inventor
Michael Wathen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE85622T1 publication Critical patent/ATE85622T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88909879T 1987-12-23 1988-10-31 Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus. ATE85622T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13738787A 1987-12-23 1987-12-23
PCT/US1988/003784 WO1989005823A1 (en) 1987-12-23 1988-10-31 Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus
EP88909879A EP0396563B1 (de) 1987-12-23 1988-10-31 Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus

Publications (1)

Publication Number Publication Date
ATE85622T1 true ATE85622T1 (de) 1993-02-15

Family

ID=22477194

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88909879T ATE85622T1 (de) 1987-12-23 1988-10-31 Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.

Country Status (14)

Country Link
US (2) US5194595A (de)
EP (1) EP0396563B1 (de)
JP (1) JP2716503B2 (de)
KR (1) KR0137963B1 (de)
AT (1) ATE85622T1 (de)
AU (1) AU617739B2 (de)
CA (1) CA1320163C (de)
DE (1) DE3878468T2 (de)
DK (1) DK173175B1 (de)
FI (1) FI102382B1 (de)
HK (1) HK166295A (de)
MX (1) MX9203458A (de)
NO (1) NO300254B1 (de)
WO (1) WO1989005823A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8914968D0 (en) * 1989-06-29 1989-08-23 Connaught Lab Production of virus and purification of viral envelope proteins for vaccine use
US6004563A (en) * 1990-11-07 1999-12-21 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
US5824307A (en) * 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
GB9200117D0 (en) 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
GB9207479D0 (en) * 1992-04-06 1992-05-20 Scotgen Ltd Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man
TW275632B (de) * 1992-04-21 1996-05-11 American Cyanamid Co
EP0678102A1 (de) * 1993-01-08 1995-10-25 The Upjohn Company Verfahren zur reinigung und rückfaltung vom fg glykoprtein des respiratorischen sincytialvirus
ATE196737T1 (de) * 1993-05-25 2000-10-15 American Cyanamid Co Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus
ATE464315T1 (de) * 1994-01-14 2010-04-15 Rath Matthias Dr Med Hydrophile signal-oligopeptide und verfahren der therapeutischen anwendung
US7300918B2 (en) 1994-01-14 2007-11-27 Matthias Rath Method of producing vaccines from protein signal oligopeptides
FR2718452B1 (fr) * 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
US5716821A (en) * 1994-09-30 1998-02-10 Uab Research Foundation Prevention and treatment of respiratory tract disease
WO1996010400A1 (en) * 1994-09-30 1996-04-11 The Uab Research Foundation Gene therapy vectors and vaccines based on non-segmented negatives stranded rna viruses
FR2726472B1 (fr) 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
DE4442114A1 (de) * 1994-11-25 1996-05-30 Buna Sow Leuna Olefinverb Gmbh Nitrit-, phosphat- und aminfreies Kühl- und Wärmeübertragungsmittel
US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
US6015664A (en) * 1995-11-03 2000-01-18 Mcw Research Foundation Multiplex PCR assay using unequal primer concentrations to detect HPIV 1,2,3 and RSV A,B and influenza virus A, B
WO1998018819A1 (en) * 1996-10-29 1998-05-07 Smithkline Beecham Biologicals S.A. Purification of respiratory syncytial virus antigens
US6103466A (en) * 1997-07-14 2000-08-15 University Of Liege Double-muscling in mammals
PT2045322E (pt) * 1997-07-14 2015-10-16 Université de Liège Musculatura dupla em mamíferos
US20070067859A1 (en) * 1997-07-14 2007-03-22 Michel Georges Double-muscling in mammals
US6699478B1 (en) * 1997-09-19 2004-03-02 Wyeth Holdings Corporation Enhanced immune response to attachment (G) protein of Respiratory Syncytial Virus
GB9909077D0 (en) 1999-04-20 1999-06-16 Smithkline Beecham Biolog Novel compositions
JP4992068B2 (ja) * 2000-01-27 2012-08-08 メディミューン，エルエルシー 超高親和性中和抗体
AU4002001A (en) 2000-03-01 2001-09-12 Med Immune Inc High potency recombinant antibodies and method for producing them
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7132100B2 (en) * 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
WO2005115337A1 (en) * 2004-05-24 2005-12-08 Polymun Scientific Immunbiologische Forschung Gmbh Superloaded liposomes for drug delivery
JP2008518936A (ja) * 2004-10-29 2008-06-05 メディミューン，インコーポレーテッド Ｒｓｖ感染症および関連状態を予防および治療する方法
EP1997830A1 (de) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV-spezifische Bindemoleküle und Mittel zu ihrer Herstellung
EP4206231A1 (de) 2007-12-24 2023-07-05 ID Biomedical Corporation of Quebec Rekombinante rsv-antigene
MX2011000668A (es) * 2008-07-18 2011-07-29 Id Biomedical Corp Quebec Antigenos quimericos polipeptidicos del virus sincitial respiratorio.
ES2583257T3 (es) 2009-06-24 2016-09-20 Glaxosmithkline Biologicals S.A. Antígenos recombinantes del VSR
ES2563730T3 (es) 2009-07-15 2016-03-16 Glaxosmithkline Biologicals S.A. Composiciones de proteína RSV F y procedimientos de fabricación de las mismas
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
SI2707385T1 (en) 2011-05-13 2018-01-31 Glaxosmithkline Biologicals Sa Pregnant RSV F antigens
EA201891945A3 (ru) 2012-08-01 2019-05-31 Бавариан Нордик А/С Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
WO1987004185A1 (en) * 1986-01-14 1987-07-16 University Of North Carolina Vaccines for human respiratory virus
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
US5001230A (en) * 1988-02-18 1991-03-19 Schering Corporation T cell activation markers
SG106639A1 (en) * 2000-10-10 2004-10-29 Gen Electric Apparatus and method for introducing small amounts of refractory elements into a vapor deposition coating

Also Published As

Publication number Publication date
FI903154A0 (fi) 1990-06-21
HK166295A (en) 1995-11-03
JP2716503B2 (ja) 1998-02-18
DK153290D0 (da) 1990-06-22
NO300254B1 (no) 1997-05-05
JPH03501723A (ja) 1991-04-18
DK153290A (da) 1990-08-16
FI102382B (fi) 1998-11-30
WO1989005823A1 (en) 1989-06-29
DE3878468D1 (de) 1993-03-25
NO902802L (no) 1990-06-22
EP0396563A1 (de) 1990-11-14
DE3878468T2 (de) 1993-06-09
KR900700508A (ko) 1990-08-13
NO902802D0 (no) 1990-06-22
CA1320163C (en) 1993-07-13
DK173175B1 (da) 2000-03-06
KR0137963B1 (ko) 1998-04-30
MX9203458A (es) 1992-09-01
AU617739B2 (en) 1991-12-05
EP0396563B1 (de) 1993-02-10
FI102382B1 (fi) 1998-11-30
US5194595A (en) 1993-03-16
AU2785089A (en) 1989-07-19
US5288630A (en) 1994-02-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time