CY1110649T1 - Στερεες, χορηγουμενες απο του στοματος φαρμακοτεχνικες μορφες με τροποποιημενη αποδεσμευση που περιεχουν ριβαροξαβανη - Google Patents

Στερεες, χορηγουμενες απο του στοματος φαρμακοτεχνικες μορφες με τροποποιημενη αποδεσμευση που περιεχουν ριβαροξαβανη

Info

Publication number
CY1110649T1
CY1110649T1 CY20101100389T CY101100389T CY1110649T1 CY 1110649 T1 CY1110649 T1 CY 1110649T1 CY 20101100389 T CY20101100389 T CY 20101100389T CY 101100389 T CY101100389 T CY 101100389T CY 1110649 T1 CY1110649 T1 CY 1110649T1
Authority
CY
Cyprus
Prior art keywords
release pharmaceutical
solid oral
form containing
pharmaceutical form
prophylaxis
Prior art date
Application number
CY20101100389T
Other languages
English (en)
Inventor
Klaus Benke
Jan-Olav Henck
Original Assignee
Bayer Schering Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36001174&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110649(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Aktiengesellschaft filed Critical Bayer Schering Pharma Aktiengesellschaft
Publication of CY1110649T1 publication Critical patent/CY1110649T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά στερεές, χορηγούμενες από του στόματος φαρμακοτεχνικές μορφές με τροποποιημένη αποδέσμευση που περιέχουν 5-χλωρο-Ν-({(5S)-2-οξο-3-[4-(3-οξο-4-μορφολινυλο)-φαινυλ]-1,3-οξαζαλιδιν-5-υλο}-μεθυλο)-2-θειο-φαινο-καρβοξαμίδιο, καθώς και μεθόδους για την παραγωγή τους, τη χρήση τους ως φαρμάκων, τη χρήση τους για προφύλαξη, δευτερογενή προφύλαξη και/ή θεραπεία νόσων, καθώς και τη χρήση τους για την παραγωγή ενός φαρμάκου για προφύλαξη, δευτερογενή προφύλαξη και/ή θεραπεία νόσων.
CY20101100389T 2004-12-24 2010-04-30 Στερεες, χορηγουμενες απο του στοματος φαρμακοτεχνικες μορφες με τροποποιημενη αποδεσμευση που περιεχουν ριβαροξαβανη CY1110649T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004062475A DE102004062475A1 (de) 2004-12-24 2004-12-24 Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
PCT/EP2005/013337 WO2006072367A1 (de) 2004-12-24 2005-12-13 Feste, oral applizierbare pharmazeutische darreichungsformen enthaltend rivaroxaban mit modifizierter freisetzung

Publications (1)

Publication Number Publication Date
CY1110649T1 true CY1110649T1 (el) 2012-05-23

Family

ID=36001174

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100389T CY1110649T1 (el) 2004-12-24 2010-04-30 Στερεες, χορηγουμενες απο του στοματος φαρμακοτεχνικες μορφες με τροποποιημενη αποδεσμευση που περιεχουν ριβαροξαβανη

Country Status (32)

Country Link
US (1) US20070026065A1 (el)
EP (1) EP1830855B1 (el)
JP (1) JP5285913B2 (el)
KR (1) KR20070094631A (el)
CN (2) CN103222969A (el)
AR (1) AR052843A1 (el)
AT (1) ATE458486T1 (el)
AU (1) AU2005324132B2 (el)
BR (1) BRPI0519376A2 (el)
CA (1) CA2591972C (el)
CY (1) CY1110649T1 (el)
DE (2) DE102004062475A1 (el)
DK (1) DK1830855T3 (el)
ES (1) ES2340053T3 (el)
GT (1) GT200500384A (el)
HN (1) HN2005036387A (el)
IL (1) IL184126A0 (el)
MA (1) MA29115B1 (el)
MX (1) MX2007007491A (el)
MY (1) MY143999A (el)
NO (1) NO20073853L (el)
NZ (1) NZ556015A (el)
PE (2) PE20081189A1 (el)
PL (1) PL1830855T3 (el)
PT (1) PT1830855E (el)
RU (1) RU2420290C2 (el)
SI (1) SI1830855T1 (el)
SV (1) SV2007002359A (el)
TW (1) TW200637558A (el)
UA (1) UA88938C2 (el)
WO (1) WO2006072367A1 (el)
ZA (1) ZA200704661B (el)

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