CY1106890T1 - Παραγωγα της ακριδινης και η χρηση τους ως φαρμακων - Google Patents
Παραγωγα της ακριδινης και η χρηση τους ως φαρμακωνInfo
- Publication number
- CY1106890T1 CY1106890T1 CY20071101236T CY071101236T CY1106890T1 CY 1106890 T1 CY1106890 T1 CY 1106890T1 CY 20071101236 T CY20071101236 T CY 20071101236T CY 071101236 T CY071101236 T CY 071101236T CY 1106890 T1 CY1106890 T1 CY 1106890T1
- Authority
- CY
- Cyprus
- Prior art keywords
- acridin
- medicines
- products
- medicaments
- tumors
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- DZBUGLKDJFMEHC-UHFFFAOYSA-N benzoquinolinylidene Natural products C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 title 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000000641 acridinyl group Chemical class C1(=CC=CC2=NC3=CC=CC=C3C=C12)* 0.000 abstract 1
- 229940027998 antiseptic and disinfectant acridine derivative Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10035927A DE10035927A1 (de) | 2000-07-21 | 2000-07-21 | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| EP01969410A EP1301485B1 (de) | 2000-07-21 | 2001-07-18 | Acridin-derivate und deren verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106890T1 true CY1106890T1 (el) | 2012-09-26 |
Family
ID=7649979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071101236T CY1106890T1 (el) | 2000-07-21 | 2007-09-26 | Παραγωγα της ακριδινης και η χρηση τους ως φαρμακων |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6706722B2 (enExample) |
| EP (1) | EP1301485B1 (enExample) |
| JP (1) | JP2004504382A (enExample) |
| KR (1) | KR20030022296A (enExample) |
| CN (1) | CN1296359C (enExample) |
| AR (1) | AR033383A1 (enExample) |
| AT (1) | ATE365717T1 (enExample) |
| AU (2) | AU2001289675B2 (enExample) |
| BG (1) | BG107507A (enExample) |
| BR (1) | BR0112591A (enExample) |
| CA (1) | CA2353360A1 (enExample) |
| CY (1) | CY1106890T1 (enExample) |
| CZ (1) | CZ2003427A3 (enExample) |
| DE (2) | DE10035927A1 (enExample) |
| DK (1) | DK1301485T3 (enExample) |
| ES (1) | ES2291349T3 (enExample) |
| HU (1) | HUP0303729A3 (enExample) |
| IL (1) | IL153476A0 (enExample) |
| MX (1) | MXPA02012564A (enExample) |
| NO (1) | NO324939B1 (enExample) |
| NZ (1) | NZ524155A (enExample) |
| PL (1) | PL358808A1 (enExample) |
| PT (1) | PT1301485E (enExample) |
| RU (1) | RU2267488C2 (enExample) |
| SK (1) | SK1932003A3 (enExample) |
| UA (1) | UA75085C2 (enExample) |
| WO (1) | WO2002008194A1 (enExample) |
| ZA (1) | ZA200210411B (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10035928A1 (de) * | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| DE10037310A1 (de) * | 2000-07-28 | 2002-02-07 | Asta Medica Ag | Neue Indolderivate und deren Verwendung als Arzneimittel |
| MXPA04012959A (es) * | 2002-06-29 | 2005-05-16 | Zentaris Gmbh | Arilcarbonilpiperacinas y heteroarilcarbonilpiperacinas y su uso para tratamiento de enfermedades de tumor benigno y maligno. |
| EP1521748A1 (de) * | 2002-07-17 | 2005-04-13 | Zentaris GmbH | Neue anthracen-derivate und deren verwendung als arzneimittel |
| US7125461B2 (en) * | 2003-05-07 | 2006-10-24 | L & L Products, Inc. | Activatable material for sealing, baffling or reinforcing and method of forming same |
| AR044586A1 (es) * | 2003-06-04 | 2005-09-21 | Aventis Pharma Sa | Productos aril - heteroaromaticos, composiciones que los contienen y su utilizacion |
| FR2855825B1 (fr) * | 2003-06-04 | 2008-08-22 | Aventis Pharma Sa | Produits aryl-heteroaromatiques, compositions les contenant et utilisation |
| US7249415B2 (en) * | 2003-06-26 | 2007-07-31 | Zephyros, Inc. | Method of forming members for sealing or baffling |
| DE10331500A1 (de) * | 2003-07-11 | 2005-02-24 | Zentaris Gmbh | Neue Acridin-Derivate und deren Verwendung als Arzneimittel |
| WO2006080043A2 (en) * | 2005-01-27 | 2006-08-03 | Alma Mater Studiorum- Universita' Di Bologna | Organic compounds useful for the treatment of alzheimer's disease, their use and method of preparation |
| US20070299093A1 (en) * | 2005-01-27 | 2007-12-27 | Alma Mater Studiorum-Universitá Di Bologna | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation |
| EP2125750B1 (en) * | 2007-02-26 | 2014-05-21 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5470557B2 (ja) * | 2007-07-26 | 2014-04-16 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成 |
| AR069207A1 (es) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| US8440658B2 (en) | 2007-12-11 | 2013-05-14 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) * | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| JP5490020B2 (ja) * | 2008-01-24 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター |
| WO2009102428A2 (en) * | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-OXAZEPAN-2-ONE AND 1,3-DIAZEPAN-2-ONE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
| CA2715290A1 (en) * | 2008-02-15 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| EP2274287B1 (en) * | 2008-03-18 | 2016-03-09 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
| EP2291373B1 (en) * | 2008-05-01 | 2013-09-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8592410B2 (en) | 2008-05-01 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11BETA-hydroxysteroid dehydrogenase 1 |
| JP5301563B2 (ja) * | 2008-05-01 | 2013-09-25 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| TW201004945A (en) | 2008-05-01 | 2010-02-01 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2010127237A2 (en) * | 2009-04-30 | 2010-11-04 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5379160B2 (ja) | 2008-07-25 | 2013-12-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| CA2729998A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8637505B2 (en) | 2009-02-04 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TW201039034A (en) * | 2009-04-27 | 2010-11-01 | Chunghwa Picture Tubes Ltd | Pixel structure and the method of forming the same |
| MA33216B1 (fr) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1 |
| EP2440537A1 (en) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| EP2448928B1 (en) | 2009-07-01 | 2014-08-13 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| EP2582698B1 (en) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| EP2585444B1 (en) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
| WO2012059416A1 (en) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2538388B1 (fr) | 1982-12-24 | 1985-06-21 | Pharmuka Lab | Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments |
| EP0318235A3 (en) * | 1987-11-25 | 1991-05-02 | Takeda Chemical Industries, Ltd. | Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof |
| US5030631A (en) * | 1989-11-27 | 1991-07-09 | Schering Corporation | Tricylclic arylsulfonamides |
| RU2126001C1 (ru) * | 1995-01-10 | 1999-02-10 | Самдзин Фармасьютикал Ко., Лтд | Производные пиперазина и фармацевтическая композиция на их основе |
| TR199800371T1 (xx) * | 1996-06-29 | 1998-06-22 | Samjin Pharmaceutical Co.Ltd. | Piperazine t�revleri ve bunlar�n haz�rlanma prosesi. |
| US5861395A (en) | 1996-09-13 | 1999-01-19 | Schering Corporation | Compounds useful for inhibition of farnesyl proteins transferase |
| FR2753706B1 (fr) | 1996-09-20 | 1998-10-30 | Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant | |
| DE19743435A1 (de) | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidinderivate |
| WO2000012074A2 (en) | 1998-08-28 | 2000-03-09 | Scios Inc. | Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase |
| CA2362495A1 (en) | 1999-03-03 | 2000-09-08 | Theresa M. Williams | Inhibitors of prenyl-protein transferases |
-
2000
- 2000-07-21 DE DE10035927A patent/DE10035927A1/de not_active Withdrawn
-
2001
- 2001-07-18 ES ES01969410T patent/ES2291349T3/es not_active Expired - Lifetime
- 2001-07-18 PT PT01969410T patent/PT1301485E/pt unknown
- 2001-07-18 CZ CZ2003427A patent/CZ2003427A3/cs unknown
- 2001-07-18 DE DE50112669T patent/DE50112669D1/de not_active Expired - Fee Related
- 2001-07-18 NZ NZ524155A patent/NZ524155A/en unknown
- 2001-07-18 WO PCT/EP2001/008263 patent/WO2002008194A1/de not_active Ceased
- 2001-07-18 AU AU2001289675A patent/AU2001289675B2/en not_active Ceased
- 2001-07-18 IL IL15347601A patent/IL153476A0/xx unknown
- 2001-07-18 RU RU2003105283/04A patent/RU2267488C2/ru not_active IP Right Cessation
- 2001-07-18 EP EP01969410A patent/EP1301485B1/de not_active Expired - Lifetime
- 2001-07-18 KR KR10-2003-7000878A patent/KR20030022296A/ko not_active Ceased
- 2001-07-18 PL PL01358808A patent/PL358808A1/xx not_active Application Discontinuation
- 2001-07-18 MX MXPA02012564A patent/MXPA02012564A/es active IP Right Grant
- 2001-07-18 AT AT01969410T patent/ATE365717T1/de not_active IP Right Cessation
- 2001-07-18 DK DK01969410T patent/DK1301485T3/da active
- 2001-07-18 HU HU0303729A patent/HUP0303729A3/hu unknown
- 2001-07-18 CN CNB018131379A patent/CN1296359C/zh not_active Expired - Fee Related
- 2001-07-18 AU AU8967501A patent/AU8967501A/xx active Pending
- 2001-07-18 SK SK193-2003A patent/SK1932003A3/sk not_active Application Discontinuation
- 2001-07-18 BR BR0112591-5A patent/BR0112591A/pt not_active IP Right Cessation
- 2001-07-18 UA UA2003021451A patent/UA75085C2/uk unknown
- 2001-07-18 JP JP2002514101A patent/JP2004504382A/ja not_active Withdrawn
- 2001-07-20 CA CA002353360A patent/CA2353360A1/en not_active Abandoned
- 2001-07-20 US US09/910,142 patent/US6706722B2/en not_active Expired - Fee Related
- 2001-07-20 AR ARP010103480A patent/AR033383A1/es unknown
-
2002
- 2002-12-23 ZA ZA200210411A patent/ZA200210411B/xx unknown
-
2003
- 2003-01-20 NO NO20030301A patent/NO324939B1/no not_active IP Right Cessation
- 2003-01-30 BG BG107507A patent/BG107507A/bg unknown
-
2007
- 2007-09-26 CY CY20071101236T patent/CY1106890T1/el unknown
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