ZA200210411B - Novel heteroaryl derivatives and the use thereof as pharmaceuticals. - Google Patents
Novel heteroaryl derivatives and the use thereof as pharmaceuticals.Info
- Publication number
- ZA200210411B ZA200210411B ZA200210411A ZA200210411A ZA200210411B ZA 200210411 B ZA200210411 B ZA 200210411B ZA 200210411 A ZA200210411 A ZA 200210411A ZA 200210411 A ZA200210411 A ZA 200210411A ZA 200210411 B ZA200210411 B ZA 200210411B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceuticals
- heteroaryl derivatives
- novel heteroaryl
- novel
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10035927A DE10035927A1 (de) | 2000-07-21 | 2000-07-21 | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200210411B true ZA200210411B (en) | 2003-02-26 |
Family
ID=7649979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200210411A ZA200210411B (en) | 2000-07-21 | 2002-12-23 | Novel heteroaryl derivatives and the use thereof as pharmaceuticals. |
Country Status (29)
Country | Link |
---|---|
US (1) | US6706722B2 (xx) |
EP (1) | EP1301485B1 (xx) |
JP (1) | JP2004504382A (xx) |
KR (1) | KR20030022296A (xx) |
CN (1) | CN1296359C (xx) |
AR (1) | AR033383A1 (xx) |
AT (1) | ATE365717T1 (xx) |
AU (2) | AU8967501A (xx) |
BG (1) | BG107507A (xx) |
BR (1) | BR0112591A (xx) |
CA (1) | CA2353360A1 (xx) |
CY (1) | CY1106890T1 (xx) |
CZ (1) | CZ2003427A3 (xx) |
DE (2) | DE10035927A1 (xx) |
DK (1) | DK1301485T3 (xx) |
ES (1) | ES2291349T3 (xx) |
HK (1) | HK1057549A1 (xx) |
HU (1) | HUP0303729A3 (xx) |
IL (1) | IL153476A0 (xx) |
MX (1) | MXPA02012564A (xx) |
NO (1) | NO324939B1 (xx) |
NZ (1) | NZ524155A (xx) |
PL (1) | PL358808A1 (xx) |
PT (1) | PT1301485E (xx) |
RU (1) | RU2267488C2 (xx) |
SK (1) | SK1932003A3 (xx) |
UA (1) | UA75085C2 (xx) |
WO (1) | WO2002008194A1 (xx) |
ZA (1) | ZA200210411B (xx) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10035928A1 (de) * | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
DE10037310A1 (de) * | 2000-07-28 | 2002-02-07 | Asta Medica Ag | Neue Indolderivate und deren Verwendung als Arzneimittel |
AU2003246571B2 (en) * | 2002-06-29 | 2008-06-26 | Zentaris Gmbh | Arylcarbonylpiperazines and heteroarylcarbonylpiperazines and the use thereof for treating benign and malignant tumour diseases |
WO2004007470A1 (de) * | 2002-07-17 | 2004-01-22 | Zentaris Gmbh | Neue anthracen-derivate und deren verwendung als arzneimittel |
US7125461B2 (en) * | 2003-05-07 | 2006-10-24 | L & L Products, Inc. | Activatable material for sealing, baffling or reinforcing and method of forming same |
AR044586A1 (es) * | 2003-06-04 | 2005-09-21 | Aventis Pharma Sa | Productos aril - heteroaromaticos, composiciones que los contienen y su utilizacion |
FR2855825B1 (fr) * | 2003-06-04 | 2008-08-22 | Aventis Pharma Sa | Produits aryl-heteroaromatiques, compositions les contenant et utilisation |
US7249415B2 (en) * | 2003-06-26 | 2007-07-31 | Zephyros, Inc. | Method of forming members for sealing or baffling |
DE10331500A1 (de) * | 2003-07-11 | 2005-02-24 | Zentaris Gmbh | Neue Acridin-Derivate und deren Verwendung als Arzneimittel |
JP2008528573A (ja) * | 2005-01-27 | 2008-07-31 | アルマ マテル ストゥディオルム−ウニヴェルシタ ディ ボローニャ | アルツハイマー病の処置に有用な有機化合物、それらの使用及び調製の方法 |
US20070299093A1 (en) * | 2005-01-27 | 2007-12-27 | Alma Mater Studiorum-Universitá Di Bologna | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation |
CA2678577A1 (en) * | 2007-02-26 | 2008-09-04 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
JP5451611B2 (ja) * | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1のサイクリックインヒビター |
AR069207A1 (es) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
TW200934490A (en) * | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
EP2252601B1 (en) * | 2008-01-24 | 2012-12-19 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
JP5734666B2 (ja) * | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の1,3−オキサアゼパン−2−オン及び1,3−ジアゼパン−2−オン阻害剤 |
JP5730021B2 (ja) * | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体 |
CA2718264A1 (en) * | 2008-03-18 | 2009-09-24 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
JP5451752B2 (ja) * | 2008-05-01 | 2014-03-26 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状インヒビター |
CA2723034A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
BRPI0911764A2 (pt) | 2008-05-01 | 2015-10-06 | Boehringer Ingelheim Int | inibidores cíclicos de 11beta-hidroxiesteroide desigrogenase 1 |
WO2009134392A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
CA2729998A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
PE20110566A1 (es) | 2008-07-25 | 2011-09-02 | Boehringer Ingelheim Int | Inhibidores ciclicos de 11beta-hidroxiesteroide deshidrogenasa 1 |
CA2744946A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
TW201039034A (en) * | 2009-04-27 | 2010-11-01 | Chunghwa Picture Tubes Ltd | Pixel structure and the method of forming the same |
GEP20156309B (en) * | 2009-04-30 | 2015-07-10 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
EP2440537A1 (en) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
US8883778B2 (en) | 2009-07-01 | 2014-11-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
EP2582698B1 (en) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
EP2585444B1 (en) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
CN103179960A (zh) | 2010-11-02 | 2013-06-26 | 贝林格尔.英格海姆国际有限公司 | 治疗代谢疾病的药物组合 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2538388B1 (fr) | 1982-12-24 | 1985-06-21 | Pharmuka Lab | Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments |
US5030631A (en) * | 1989-11-27 | 1991-07-09 | Schering Corporation | Tricylclic arylsulfonamides |
EP0850222B1 (en) * | 1996-06-29 | 2003-05-28 | Samjin Pharmaceutical Co., Ltd. | Piperazine derivatives and process for the preparation thereof |
US5861395A (en) | 1996-09-13 | 1999-01-19 | Schering Corporation | Compounds useful for inhibition of farnesyl proteins transferase |
FR2753706B1 (fr) | 1996-09-20 | 1998-10-30 | Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant | |
DE19743435A1 (de) | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidinderivate |
IL141724A0 (en) | 1998-08-28 | 2002-03-10 | Scios Inc | INHIBITORS OF P38-α KINASE |
WO2000051614A1 (en) | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferases |
-
2000
- 2000-07-21 DE DE10035927A patent/DE10035927A1/de not_active Withdrawn
-
2001
- 2001-07-18 AT AT01969410T patent/ATE365717T1/de not_active IP Right Cessation
- 2001-07-18 KR KR10-2003-7000878A patent/KR20030022296A/ko not_active Application Discontinuation
- 2001-07-18 AU AU8967501A patent/AU8967501A/xx active Pending
- 2001-07-18 BR BR0112591-5A patent/BR0112591A/pt not_active IP Right Cessation
- 2001-07-18 JP JP2002514101A patent/JP2004504382A/ja not_active Withdrawn
- 2001-07-18 EP EP01969410A patent/EP1301485B1/de not_active Expired - Lifetime
- 2001-07-18 CN CNB018131379A patent/CN1296359C/zh not_active Expired - Fee Related
- 2001-07-18 RU RU2003105283/04A patent/RU2267488C2/ru not_active IP Right Cessation
- 2001-07-18 CZ CZ2003427A patent/CZ2003427A3/cs unknown
- 2001-07-18 AU AU2001289675A patent/AU2001289675B2/en not_active Ceased
- 2001-07-18 UA UA2003021451A patent/UA75085C2/uk unknown
- 2001-07-18 ES ES01969410T patent/ES2291349T3/es not_active Expired - Lifetime
- 2001-07-18 MX MXPA02012564A patent/MXPA02012564A/es active IP Right Grant
- 2001-07-18 SK SK193-2003A patent/SK1932003A3/sk not_active Application Discontinuation
- 2001-07-18 DE DE50112669T patent/DE50112669D1/de not_active Expired - Fee Related
- 2001-07-18 WO PCT/EP2001/008263 patent/WO2002008194A1/de active IP Right Grant
- 2001-07-18 PT PT01969410T patent/PT1301485E/pt unknown
- 2001-07-18 IL IL15347601A patent/IL153476A0/xx unknown
- 2001-07-18 DK DK01969410T patent/DK1301485T3/da active
- 2001-07-18 PL PL01358808A patent/PL358808A1/xx not_active Application Discontinuation
- 2001-07-18 NZ NZ524155A patent/NZ524155A/en unknown
- 2001-07-18 HU HU0303729A patent/HUP0303729A3/hu unknown
- 2001-07-20 CA CA002353360A patent/CA2353360A1/en not_active Abandoned
- 2001-07-20 US US09/910,142 patent/US6706722B2/en not_active Expired - Fee Related
- 2001-07-20 AR ARP010103480A patent/AR033383A1/es unknown
-
2002
- 2002-12-23 ZA ZA200210411A patent/ZA200210411B/xx unknown
-
2003
- 2003-01-20 NO NO20030301A patent/NO324939B1/no not_active IP Right Cessation
- 2003-01-30 BG BG107507A patent/BG107507A/bg unknown
-
2004
- 2004-01-15 HK HK04100290A patent/HK1057549A1/xx not_active IP Right Cessation
-
2007
- 2007-09-26 CY CY20071101236T patent/CY1106890T1/el unknown
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