CY1105202T1 - Διασπειρομενες φαρμακευτικες συνθεσεις - Google Patents
Διασπειρομενες φαρμακευτικες συνθεσειςInfo
- Publication number
- CY1105202T1 CY1105202T1 CY20061101293T CY061101293T CY1105202T1 CY 1105202 T1 CY1105202 T1 CY 1105202T1 CY 20061101293 T CY20061101293 T CY 20061101293T CY 061101293 T CY061101293 T CY 061101293T CY 1105202 T1 CY1105202 T1 CY 1105202T1
- Authority
- CY
- Cyprus
- Prior art keywords
- excipient
- prevention
- treatment
- pharmaceutical compositions
- administration
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 208000005141 Otitis Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000008365 aqueous carrier Substances 0.000 abstract 1
- 235000013365 dairy product Nutrition 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000019258 ear infection Diseases 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 208000004396 mastitis Diseases 0.000 abstract 1
- 235000019808 microcrystalline wax Nutrition 0.000 abstract 1
- 239000004200 microcrystalline wax Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Παρέχεται φαρμακευτική σύνθεση περιλαμβάνουσα ένα έκδοχο το οποίο περιλαμβάνει (α) ένα αμφιπαθικό έλαιο το οποίο είναι διασπειρόμενο στο νερό και αδιάλυτο στην αιθανόλη, (β) μικροκρυσταλλικό κηρό και (γ) φαρμακευτικώς αποδεκτό μη-υδατικό φορέα και που έχει αντιβακτηριακή ουσία σε αντιβακτηριακώς αποτελεσματική ποσότητα σταθερώς διασπαρμένη στο έκδοχο. Η σύνθεση είναι κατάλληλη για χορήγηση με ενδομαστική έγχυση σε ένα γαλακτοπαραγωγό ζώο για θεραπεία ή/και πρόληψη μαστίτιδας ή άλλων ασθενειών του μαστού ζώου, καθώς επίσης για ωτική χορήγηση για θεραπεία και πρόληψη μόλυνσης του ωτός.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43498502P | 2002-12-19 | 2002-12-19 | |
US10/687,986 US7842791B2 (en) | 2002-12-19 | 2003-10-17 | Dispersible pharmaceutical compositions |
PCT/US2003/039508 WO2004060345A2 (en) | 2002-12-19 | 2003-12-11 | Dispersible pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1105202T1 true CY1105202T1 (el) | 2010-03-03 |
Family
ID=32717791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101293T CY1105202T1 (el) | 2002-12-19 | 2006-09-12 | Διασπειρομενες φαρμακευτικες συνθεσεις |
Country Status (25)
Country | Link |
---|---|
US (1) | US7842791B2 (el) |
EP (1) | EP1575618B1 (el) |
JP (1) | JP3803683B2 (el) |
KR (1) | KR100752836B1 (el) |
CN (1) | CN100355457C (el) |
AR (1) | AR042537A1 (el) |
AT (1) | ATE336264T1 (el) |
AU (1) | AU2003296947B2 (el) |
BR (1) | BR0317104B1 (el) |
CA (1) | CA2504065C (el) |
CY (1) | CY1105202T1 (el) |
DE (1) | DE60307677T2 (el) |
DK (1) | DK1575618T3 (el) |
ES (1) | ES2268496T3 (el) |
HK (1) | HK1081457A1 (el) |
MX (1) | MXPA05006739A (el) |
NO (1) | NO20052306L (el) |
NZ (1) | NZ540715A (el) |
PL (1) | PL377518A1 (el) |
PT (1) | PT1575618E (el) |
RU (1) | RU2311201C2 (el) |
SI (1) | SI1575618T1 (el) |
TW (1) | TW200420299A (el) |
WO (1) | WO2004060345A2 (el) |
ZA (1) | ZA200504873B (el) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
WO2004037225A2 (en) | 2002-10-25 | 2004-05-06 | Foamix Ltd. | Cosmetic and pharmaceutical foam |
US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US20050009931A1 (en) * | 2003-03-20 | 2005-01-13 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
US20040214753A1 (en) * | 2003-03-20 | 2004-10-28 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
US20050004098A1 (en) * | 2003-03-20 | 2005-01-06 | Britten Nancy Jean | Dispersible formulation of an anti-inflammatory agent |
CN1829510A (zh) * | 2003-07-31 | 2006-09-06 | 法马西亚和厄普乔恩公司 | 抗炎剂的可分散性制剂 |
US20060046970A1 (en) * | 2004-08-31 | 2006-03-02 | Insite Vision Incorporated | Topical otic compositions and methods of topical treatment of prevention of otic infections |
WO2006077856A1 (ja) * | 2005-01-19 | 2006-07-27 | Nippon Zenyaku Kogyo Co., Ltd. | 乳房炎用注入剤 |
KR100748252B1 (ko) | 2006-05-08 | 2007-08-10 | 주식회사 삼양애니팜 | 플로르페니콜 및 타이로신 함유 주사용 조성물 |
WO2008025773A1 (en) * | 2006-08-30 | 2008-03-06 | Intervet International B.V. | Pharmaceutical compositions comprising cefquinome |
US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
WO2008096918A1 (en) * | 2007-02-09 | 2008-08-14 | Kolon Industries, Inc | Reactive antibioties and a method of preparing the same and antibacterial fiber treated thereby |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
WO2009069006A2 (en) | 2007-11-30 | 2009-06-04 | Foamix Ltd. | Foam containing benzoyl peroxide |
WO2009090495A2 (en) | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
WO2010008995A2 (en) * | 2008-07-14 | 2010-01-21 | Otonomy, Inc. | Controlled-release apoptosis modulating compositions and methods for the treatment of otic disorders |
WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
CN101804058A (zh) * | 2010-04-22 | 2010-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | 一种用于防治奶牛干奶期乳房炎的药物及制备方法 |
CN103379917B (zh) * | 2010-11-01 | 2016-10-12 | 梅琳塔治疗公司 | 药物组合物 |
CN102058612B (zh) * | 2011-01-06 | 2012-07-04 | 河南亚卫动物药业有限公司 | 一种兽用复方乳浊液及其制备方法 |
WO2013056079A1 (en) * | 2011-10-13 | 2013-04-18 | The Johns Hopkins University | High affinity beta lactamase inhibitors |
KR101352867B1 (ko) | 2011-11-07 | 2014-01-21 | 주식회사 한동 | 동물용 복합항생제 조성물 |
PT2819699T (pt) * | 2012-02-27 | 2019-08-21 | Bayer New Zealand Ltd | Composições de libertação controlada e os seus métodos de utilização |
CN103479660A (zh) * | 2012-06-14 | 2014-01-01 | 符波 | 一种治疗奶牛临床型乳房炎的乳房注入剂及其制备方法 |
KR101458611B1 (ko) * | 2012-08-02 | 2014-11-11 | 주식회사 한동 | 동물용 복합항생제 조성물 |
RU2662300C2 (ru) * | 2013-02-08 | 2018-07-25 | Луода Фарма Пти Лимитед | Способы лечения микробных инфекций, в том числе мастита |
US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
CN106265595B (zh) * | 2016-09-29 | 2019-05-03 | 甘肃瑞和祥生物科技有限公司 | 一种肠溶吉他霉素缓释微球及其制备方法 |
CN106361707B (zh) * | 2016-09-30 | 2019-02-26 | 广东温氏大华农生物科技有限公司 | 一种酒石酸泰万菌素颗粒制剂及其制备方法 |
CN109045044B (zh) * | 2018-07-04 | 2020-11-17 | 佛山市南海东方澳龙制药有限公司 | 一种复方药剂及其制备方法、用途 |
CN112716898A (zh) * | 2021-02-22 | 2021-04-30 | 青岛康地恩动物药业有限公司 | 一种替米考星自乳化口服制剂及其制备方法 |
Family Cites Families (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA670254A (en) | 1963-09-10 | E. Gouge Hardin | Mastitis composition | |
US3144386A (en) | 1958-05-09 | 1964-08-11 | Merck & Co Inc | Mastitis aerosol foam |
GB980282A (en) | 1960-03-24 | 1965-01-13 | Philips Roxane | Antibiotic mastitis composition |
US3135658A (en) | 1961-10-10 | 1964-06-02 | Merck & Co Inc | Non-aqueous oleaginous aerosol foam therapy of bovine mastitis |
US3347743A (en) | 1964-01-03 | 1967-10-17 | Richardson Merrell Inc | Method of treating bovine masititis |
GB1089523A (en) | 1964-06-25 | 1967-11-01 | Astra Hewlett Ltd | Improvements in or relating to veterinary compositions for treating mastitis |
GB1181527A (en) | 1966-09-21 | 1970-02-18 | Douglas Gabriel Parizeau | Composition and Method for Treating Mastitis with Therapeutic Agents. |
US3531481A (en) | 1969-04-21 | 1970-09-29 | Lilly Co Eli | Method for manufacture of crystalline cephalosporin |
US3636194A (en) | 1969-10-23 | 1972-01-18 | Douglas G Parizeau | Composition and method for treating mastitis with therapeutic agents |
DE2063896A1 (de) | 1970-12-28 | 1972-07-20 | Dynamit Nobel Ag, 5210 Troisdorf | Salbengrundlagen auf der Basis von Triglyceriden gesättigter mittelkettiger Fettsäuren und Verfahren zu deren Herstellung |
CA1052697A (en) | 1974-03-29 | 1979-04-17 | Upjohn Company (The) | Composition for treating mastitis in animals |
DK154939C (da) | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
US4006138A (en) | 1975-04-11 | 1977-02-01 | Eli Lilly And Company | Crystalline form of sodium O-formylcefamandole |
US4011312A (en) | 1975-06-25 | 1977-03-08 | American Home Products Corporation | Prolonged release drug form for the treatment of bovine mastitis |
GB1547164A (en) | 1975-08-14 | 1979-06-06 | Beecham Group Ltd | Veterinary compositions |
GB1589917A (en) | 1976-11-27 | 1981-05-20 | Beecham Group Ltd | Pharmaceutical composition containing a clavulanic acid derivative |
DE2760123C2 (de) | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
GB1532682A (en) | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
US4172138A (en) | 1977-03-23 | 1979-10-23 | Rhodes Russell E | Method and composition of matter for the treatment of dry cows for mastitis |
US4104470A (en) | 1977-06-03 | 1978-08-01 | Eli Lilly And Company | Crystallization process for cefazolin sodium |
FR2414509A1 (fr) | 1978-01-17 | 1979-08-10 | Glaxo Group Ltd | Procede de cristallisation de cefuroxime sodique |
FI65914C (fi) | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
US4299501A (en) * | 1979-08-10 | 1981-11-10 | Ortho Pharmaceutical Corporation | Continuous process for the preparation of semisolid dispersions |
FR2479229B1 (fr) | 1980-03-26 | 1986-01-17 | Clin Midy | Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives |
NL8002636A (nl) | 1980-05-08 | 1981-12-01 | Gist Brocades Nv | Solvaat van amoxicilline, werkwijze ter bereiding hiervan en werkwijze ter bereiding van injectiepreparaten uit dit solvaat. |
EP0058015A3 (en) | 1981-02-05 | 1982-08-25 | Beecham Group Plc | Treatment of infections |
JPS57134482A (en) | 1981-02-13 | 1982-08-19 | Dainippon Pharmaceut Co Ltd | 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation |
US4400503A (en) | 1981-10-30 | 1983-08-23 | Eli Lilly And Company | Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid |
JPS58198489A (ja) | 1982-05-14 | 1983-11-18 | Meiji Seika Kaisha Ltd | 7β−(2D−2−アミノ−2−カルボキシエチルチオアセトアミド)−7α−メトキシ−3−(1−メチル−1H−テトラゾ−ル−5−イル)−チオメチル−3−セフエム−4−カルボン酸ナトリウム塩の七水和物及びその製造方法 |
YU44680B (en) | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
US4474780A (en) | 1983-07-22 | 1984-10-02 | Eli Lilly And Company | Crystalline cephalosporin |
DE3313818A1 (de) | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
JPS60120886A (ja) | 1983-12-02 | 1985-06-28 | Takeda Chem Ind Ltd | セフェムカルボン酸のナトリウム塩の結晶 |
US4616080A (en) | 1984-07-02 | 1986-10-07 | Eli Lilly And Company | Simplified process of forming crystalline ceftazidime pentahydrate |
EP0170623B1 (en) * | 1984-08-02 | 1990-11-28 | Sandoz Ag | Novel pharmaceutical use of (nva)2-cyclosporine |
US4902683A (en) * | 1984-10-25 | 1990-02-20 | The Upjohn Company | Crystalline cephalosporin hydrohalide salts |
WO1987001117A2 (en) | 1985-08-12 | 1987-02-26 | The Upjohn Company | Conversion of cephalosporin hydrohalide salt to alkali metal salt |
IT1190445B (it) | 1985-11-08 | 1988-02-16 | Fatro Spa | Composizioni veterinarie a base di agenti antimicrobici e loro impiego |
HU194493B (en) | 1985-11-27 | 1988-02-29 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing primycin-containing colloidal basic gel and compositions comprising the same |
GB8531609D0 (en) | 1985-12-23 | 1986-02-05 | Beecham Group Plc | Compounds |
NZ220764A (en) | 1986-07-02 | 1989-09-27 | Shionogi & Co | Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions |
US5017380A (en) | 1986-07-02 | 1991-05-21 | Shionogi & Co., Ltd. | Gelatin hard capsule containing crystalline hydrate of oral cephalosporin |
CH668187A5 (de) * | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
GB8621484D0 (en) | 1986-09-05 | 1986-10-15 | Norbrook Lab Ltd | Intramammary infusion |
US4723112A (en) | 1986-09-19 | 1988-02-02 | Tektronix, Inc. | Level shift circuit for differential signals |
GB8629481D0 (en) | 1986-12-10 | 1987-01-21 | Beecham Group Plc | Veterinary treatment |
IT1214587B (it) | 1986-12-23 | 1990-01-18 | Giovanni Bonfanti | Metodo per la produzione diprodotti cristallini puri. |
ES2032543T3 (es) | 1987-02-02 | 1993-02-16 | Eli Lilly And Company | Procedimiento mejorado de preparacion de un antibiotico. |
US5079007A (en) | 1987-07-29 | 1992-01-07 | The Upjohn Company | Controlled release of antibiotic salts from an implant |
US4898938A (en) | 1987-08-03 | 1990-02-06 | Rifar S.R.L. | Method for preparing crystalline cefadroxil monohydrate |
US4877782A (en) | 1988-02-16 | 1989-10-31 | The Upjohn Company | Zinc ceftiofur complexes |
FR2635463A1 (fr) | 1988-08-19 | 1990-02-23 | Veprol | Composition pharmaceutique comportant un principe actif peu soluble dans l'eau et au moins un glyceride gelifie par au moins un polymere cellulosique |
EP0361928B1 (en) * | 1988-09-29 | 1994-04-27 | Shiseido Company Limited | Emulsified composition |
DE3919259A1 (de) | 1989-06-13 | 1990-12-20 | Hoechst Ag | Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung |
US5143137A (en) | 1990-03-08 | 1992-09-01 | Rite-Hite Corporation | Overlapping seal for insulated folding door |
US5284662A (en) * | 1990-10-01 | 1994-02-08 | Ciba-Geigy Corp. | Oral osmotic system for slightly soluble active agents |
US5342612A (en) | 1991-12-20 | 1994-08-30 | American Cyanamid Company | Compositions for the treatment of mammalian diseases |
US5314685A (en) | 1992-05-11 | 1994-05-24 | Agouron Pharmaceuticals, Inc. | Anhydrous formulations for administering lipophilic agents |
ES2079994B1 (es) | 1992-10-07 | 1996-08-01 | Cusi Lab | Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica. |
WO1995031180A1 (en) | 1992-12-08 | 1995-11-23 | Bimeda Research And Development Limited | A veterinary composition |
AU5574294A (en) | 1992-12-08 | 1994-07-04 | Bimeda Research & Development Limited | Aqueous antibiotic composition for veterinary use |
KR100296810B1 (ko) | 1993-03-12 | 2001-10-24 | 로렌스 티. 마이젠헬더 | 결정성세프티오퍼유리산 |
NZ511762A (en) | 1993-07-19 | 2003-09-26 | Univ British Columbia | Anti-angiogenic compositions and methods of use |
US6054136A (en) | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
DE4340781C3 (de) | 1993-11-30 | 2000-01-27 | Novartis Ag | Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung |
US5635159A (en) | 1994-08-26 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing polyglycolyzed glycerides |
NZ309624A (en) | 1995-06-06 | 1999-04-29 | Bayer Ag | Non-irritating, non-sensitizing, non-ototoxic (harmful to the ears) antibacterial compositions |
US5736151A (en) * | 1996-12-09 | 1998-04-07 | Pharmacia & Upjohn Company | Antibiotic oil suspensions |
AU3843999A (en) | 1998-05-07 | 1999-11-23 | Elan Corporation, Plc | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
TW537894B (en) | 1998-05-26 | 2003-06-21 | Novartis Ag | A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist |
EP0982035B1 (en) | 1998-08-18 | 2004-03-31 | Panacea Biotec Limited | Cyclosporin composition comprising an hydrophilic carrier |
AR020660A1 (es) | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Composiciones antibioticas para el tratamiento de ojos, oidos y nariz |
US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
US6440964B1 (en) | 1998-09-30 | 2002-08-27 | Alcon Manufacturing, Ltd. | Compositions and methods for treating ophthalmic and otic infections |
IT1303793B1 (it) | 1998-11-27 | 2001-02-23 | Promefarm S R L | "composizione farmaceutica comprendente un composto organico donatoredi ossido nitrico (no)" |
GB9903547D0 (en) * | 1999-02-16 | 1999-04-07 | Novartis Ag | Organic compounds |
GB9922710D0 (en) * | 1999-09-24 | 1999-11-24 | Bayer Ag | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatatives for the treatment of multiple sclerosis |
US20010049366A1 (en) | 2000-02-09 | 2001-12-06 | Alcon Universal Ltd. | Topical solution formulations containing an antibiotic and a corticosteroid |
WO2001089495A2 (en) | 2000-05-19 | 2001-11-29 | Alcon Laboratories, Inc. | Antibiotic compositions containing quinolone derivatives for treatment of the eye, ear and nose |
DK1317256T3 (da) * | 2000-09-12 | 2009-01-26 | Pharmacia & Upjohn Co Llc | Farmaceutisk sammensætning havende en modificeret bærer |
-
2003
- 2003-10-17 US US10/687,986 patent/US7842791B2/en active Active
- 2003-12-11 CA CA2504065A patent/CA2504065C/en not_active Expired - Lifetime
- 2003-12-11 PL PL377518A patent/PL377518A1/pl not_active Application Discontinuation
- 2003-12-11 DE DE60307677T patent/DE60307677T2/de not_active Expired - Lifetime
- 2003-12-11 NZ NZ540715A patent/NZ540715A/en unknown
- 2003-12-11 BR BRPI0317104A patent/BR0317104B1/pt active IP Right Grant
- 2003-12-11 AT AT03814728T patent/ATE336264T1/de not_active IP Right Cessation
- 2003-12-11 DK DK03814728T patent/DK1575618T3/da active
- 2003-12-11 RU RU2005119159/15A patent/RU2311201C2/ru not_active IP Right Cessation
- 2003-12-11 KR KR1020057011386A patent/KR100752836B1/ko not_active IP Right Cessation
- 2003-12-11 CN CNB2003801048633A patent/CN100355457C/zh not_active Expired - Lifetime
- 2003-12-11 AU AU2003296947A patent/AU2003296947B2/en not_active Ceased
- 2003-12-11 SI SI200330409T patent/SI1575618T1/sl unknown
- 2003-12-11 MX MXPA05006739A patent/MXPA05006739A/es active IP Right Grant
- 2003-12-11 PT PT03814728T patent/PT1575618E/pt unknown
- 2003-12-11 WO PCT/US2003/039508 patent/WO2004060345A2/en active IP Right Grant
- 2003-12-11 JP JP2004565402A patent/JP3803683B2/ja not_active Expired - Lifetime
- 2003-12-11 EP EP03814728A patent/EP1575618B1/en not_active Expired - Lifetime
- 2003-12-11 ES ES03814728T patent/ES2268496T3/es not_active Expired - Lifetime
- 2003-12-18 AR ARP030104717A patent/AR042537A1/es not_active Application Discontinuation
- 2003-12-18 TW TW092135958A patent/TW200420299A/zh unknown
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2005
- 2005-05-11 NO NO20052306A patent/NO20052306L/no not_active Application Discontinuation
- 2005-06-14 ZA ZA200504873A patent/ZA200504873B/en unknown
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2006
- 2006-02-15 HK HK06101908A patent/HK1081457A1/xx not_active IP Right Cessation
- 2006-09-12 CY CY20061101293T patent/CY1105202T1/el unknown
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