EA200900211A1 - Замещенные производные имидазолона, их получение и применение - Google Patents
Замещенные производные имидазолона, их получение и применениеInfo
- Publication number
- EA200900211A1 EA200900211A1 EA200900211A EA200900211A EA200900211A1 EA 200900211 A1 EA200900211 A1 EA 200900211A1 EA 200900211 A EA200900211 A EA 200900211A EA 200900211 A EA200900211 A EA 200900211A EA 200900211 A1 EA200900211 A1 EA 200900211A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- receiving
- application
- derivatives
- imidazolone derivatives
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение касается полизамещенных производных имидазолонов, фармацевтических композиций, включающих такие производные, и их терапевтического применения в области охраны здоровья человека и животных. Настоящее изобретение также касается способа получения этих производных.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606752A FR2903984B1 (fr) | 2006-07-24 | 2006-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
PCT/FR2007/051716 WO2008012470A2 (fr) | 2006-07-24 | 2007-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200900211A1 true EA200900211A1 (ru) | 2009-06-30 |
Family
ID=37843186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200900211A EA200900211A1 (ru) | 2006-07-24 | 2007-07-24 | Замещенные производные имидазолона, их получение и применение |
Country Status (16)
Country | Link |
---|---|
US (1) | US20100004159A1 (ru) |
EP (1) | EP2049107A2 (ru) |
JP (1) | JP2009544675A (ru) |
KR (1) | KR20090038469A (ru) |
CN (1) | CN101522192A (ru) |
AU (1) | AU2007279135A1 (ru) |
BR (1) | BRPI0715326A2 (ru) |
CA (1) | CA2658625A1 (ru) |
EA (1) | EA200900211A1 (ru) |
FR (1) | FR2903984B1 (ru) |
IL (1) | IL196671A0 (ru) |
MX (1) | MX2009000900A (ru) |
NO (1) | NO20090348L (ru) |
NZ (1) | NZ575011A (ru) |
WO (1) | WO2008012470A2 (ru) |
ZA (1) | ZA200901268B (ru) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
AU2011232657A1 (en) * | 2010-03-26 | 2012-09-27 | Merck Sharp & Dohme Corp. | Novel spiro imidazolone derivatives as glucagon receptor antagonists, compositions, and methods for their use |
US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
WO2012009226A1 (en) * | 2010-07-13 | 2012-01-19 | Merck Sharp & Dohme Corp. | Substituted imidazolones, compositions containing such compounds and methods of use |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
ES2784489T3 (es) * | 2013-06-27 | 2020-09-28 | Lg Chemical Ltd | Derivados de biarilo como agonistas de GPR120 |
EP3083600B1 (en) | 2013-12-17 | 2018-09-26 | Janssen Pharmaceutica NV | Imidazolin-5-one derivatives useful as fasn inhibitors for the treatment of cancer |
CN105439946B (zh) * | 2014-08-13 | 2018-02-02 | 益方生物科技(上海)有限公司 | 羧酸化合物及其制备方法和用途 |
CN104177298B (zh) * | 2014-09-18 | 2018-10-02 | 湘潭大学 | 4,4-二取代-4,5-二氢-1h–咪唑-5-酮、衍生物及其合成方法 |
EP3324952B1 (en) | 2015-07-17 | 2020-12-16 | Institut Pasteur | 5-hydroxytryptamine 1b receptor-stimulating agent for use as a promoter of satellite cells self-renewal and/or differentiation |
US20180305341A1 (en) * | 2015-09-11 | 2018-10-25 | Raqualia Pharma Inc. | Imidazolinone derivatives as trpm8 antagonists |
KR102375929B1 (ko) | 2016-03-31 | 2022-03-16 | 온크터널 테라퓨틱스, 인코포레이티드. | 인돌린 유사체 및 이의 용도 |
EP3484462B1 (en) | 2016-07-15 | 2022-12-14 | Institut Pasteur | 5-hydroxytryptamine 1b receptor-stimulating agent for skin and/or hair repair |
CN113121394B (zh) * | 2019-12-30 | 2022-11-08 | 中国药科大学 | 一种苯氧乙酸类衍生物的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0214437A (pt) * | 2001-11-30 | 2004-10-13 | Lilly Co Eli | Composto, composição farmacêutica, métodos de modular um receptor ativado por proliferador de peroxissoma, de tratar e de prevenir a diabete melito, e de tratar a sìndrome x, e doenças cardiovasculares em um mamìfero, e, uso de um composto |
US7232828B2 (en) * | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
US20050020654A1 (en) * | 2003-03-15 | 2005-01-27 | Pershadsingh Harrihar A. | Novel PPAR agonists, pharmaceutical compositions and uses thereof |
-
2006
- 2006-07-24 FR FR0606752A patent/FR2903984B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-24 WO PCT/FR2007/051716 patent/WO2008012470A2/fr active Application Filing
- 2007-07-24 NZ NZ575011A patent/NZ575011A/en not_active IP Right Cessation
- 2007-07-24 BR BRPI0715326-0A patent/BRPI0715326A2/pt not_active IP Right Cessation
- 2007-07-24 US US12/309,642 patent/US20100004159A1/en not_active Abandoned
- 2007-07-24 CN CNA2007800352070A patent/CN101522192A/zh active Pending
- 2007-07-24 JP JP2009521318A patent/JP2009544675A/ja active Pending
- 2007-07-24 EA EA200900211A patent/EA200900211A1/ru unknown
- 2007-07-24 MX MX2009000900A patent/MX2009000900A/es active IP Right Grant
- 2007-07-24 KR KR1020097003832A patent/KR20090038469A/ko not_active Application Discontinuation
- 2007-07-24 AU AU2007279135A patent/AU2007279135A1/en not_active Abandoned
- 2007-07-24 CA CA002658625A patent/CA2658625A1/fr not_active Abandoned
- 2007-07-24 EP EP07823633A patent/EP2049107A2/fr not_active Withdrawn
-
2009
- 2009-01-22 NO NO20090348A patent/NO20090348L/no not_active Application Discontinuation
- 2009-01-22 IL IL196671A patent/IL196671A0/en unknown
- 2009-02-23 ZA ZA200901268A patent/ZA200901268B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP2049107A2 (fr) | 2009-04-22 |
NZ575011A (en) | 2011-12-22 |
JP2009544675A (ja) | 2009-12-17 |
MX2009000900A (es) | 2009-06-18 |
CN101522192A (zh) | 2009-09-02 |
US20100004159A1 (en) | 2010-01-07 |
KR20090038469A (ko) | 2009-04-20 |
NO20090348L (no) | 2009-04-24 |
BRPI0715326A2 (pt) | 2013-08-13 |
WO2008012470A2 (fr) | 2008-01-31 |
FR2903984B1 (fr) | 2008-10-03 |
CA2658625A1 (fr) | 2008-01-31 |
ZA200901268B (en) | 2010-04-28 |
IL196671A0 (en) | 2009-11-18 |
AU2007279135A1 (en) | 2008-01-31 |
WO2008012470A3 (fr) | 2008-03-20 |
FR2903984A1 (fr) | 2008-01-25 |
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