CS221845B2 - Method of making the ethanolamine derivatives - Google Patents
Method of making the ethanolamine derivatives Download PDFInfo
- Publication number
- CS221845B2 CS221845B2 CS815265A CS526581A CS221845B2 CS 221845 B2 CS221845 B2 CS 221845B2 CS 815265 A CS815265 A CS 815265A CS 526581 A CS526581 A CS 526581A CS 221845 B2 CS221845 B2 CS 221845B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- compound
- hydrogen
- group
- sup
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Luminescent Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8022439 | 1980-07-09 | ||
GB8116441 | 1981-05-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS221845B2 true CS221845B2 (en) | 1983-04-29 |
Family
ID=26276161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS815265A CS221845B2 (en) | 1980-07-09 | 1981-07-08 | Method of making the ethanolamine derivatives |
Country Status (29)
Country | Link |
---|---|
US (2) | US4419364A (da) |
EP (1) | EP0043807B1 (da) |
KR (3) | KR850000301B1 (da) |
AT (1) | ATE7689T1 (da) |
AU (1) | AU539976B2 (da) |
CA (1) | CA1180021A (da) |
CS (1) | CS221845B2 (da) |
CY (1) | CY1273A (da) |
DD (1) | DD202001A5 (da) |
DE (1) | DE3163871D1 (da) |
DK (1) | DK157678C (da) |
ES (3) | ES8300678A1 (da) |
FI (1) | FI73666C (da) |
GR (1) | GR74291B (da) |
HK (1) | HK5385A (da) |
HU (2) | HU187611B (da) |
IE (1) | IE51373B1 (da) |
IS (1) | IS1262B6 (da) |
LU (1) | LU88304I2 (da) |
MX (1) | MX9203239A (da) |
MY (1) | MY8700026A (da) |
NO (2) | NO152130C (da) |
NZ (1) | NZ197628A (da) |
PH (2) | PH16535A (da) |
PL (1) | PL128513B1 (da) |
PT (1) | PT73336B (da) |
SG (1) | SG79784G (da) |
SU (1) | SU1128830A3 (da) |
YU (3) | YU42116B (da) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8904064D0 (sv) * | 1989-12-01 | 1989-12-01 | Astra Ab | Improved method of preparing an intermediate for the manufacture of bambuterol |
SE9000948D0 (sv) * | 1990-03-16 | 1990-03-16 | Draco Ab | New use |
US5830422A (en) * | 1995-06-23 | 1998-11-03 | Ormiston Mining And Smelting Co. Ltd. | Method for production of sodium bicarbonate, sodium carbonate and ammonium sulfate from sodium sulfate |
CA2247953A1 (en) * | 1996-01-29 | 1997-07-31 | E. Charles Pesterfield Jr. | Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists |
SE9604752D0 (sv) * | 1996-12-20 | 1996-12-20 | Astra Ab | Formulation and use |
KR20030085658A (ko) * | 2002-04-30 | 2003-11-07 | 한올제약주식회사 | 밤부테롤의 개선된 합성방법 |
ES2312669T3 (es) * | 2002-08-08 | 2009-03-01 | Wen Tan | R-bambuterol, su preparacion y usos terapeuticos. |
US7495028B2 (en) * | 2002-08-08 | 2009-02-24 | Wen Tan | R-bambuterol, its preparation and therapeutic uses |
CA2537185A1 (en) * | 2003-08-29 | 2005-03-10 | Ranbaxy Laboratories Limited | Inhibitors of phosphodiesterase type-iv |
EP1694655A2 (en) * | 2003-11-26 | 2006-08-30 | Ranbaxy Laboratories Limited | Phosphodiesterase inhibitors |
WO2006081986A1 (en) * | 2005-02-07 | 2006-08-10 | F.Hoffmann-La Roche Ag | Bambuterol and integrin inhibitor combination |
WO2007031838A1 (en) | 2005-09-16 | 2007-03-22 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
EP1948164A1 (en) | 2005-10-19 | 2008-07-30 | Ranbaxy Laboratories, Ltd. | Pharmaceutical compositions of muscarinic receptor antagonists |
RU2008119322A (ru) * | 2005-10-19 | 2009-11-27 | Рэнбакси Лабораториз Лимитед (In) | Композиции ингибиторов фосфодиэстеразы iv типа |
SI2074093T1 (sl) | 2006-08-22 | 2012-12-31 | Ranbaxy Laboratories Limited | Postopek za pridobitev inhibitorjev matrične metalproteinaze in kiralni pomožnik zanj |
CN101616901A (zh) * | 2006-09-22 | 2009-12-30 | 兰贝克赛实验室有限公司 | Iv型磷酸二酯酶的抑制剂 |
US20100029728A1 (en) * | 2006-09-22 | 2010-02-04 | Ranbaxy Laboratories Limited | Phosphodiesterase inhibitors |
EP1958947A1 (en) | 2007-02-15 | 2008-08-20 | Ranbaxy Laboratories Limited | Inhibitors of phosphodiesterase type 4 |
SI2124944T1 (sl) | 2007-03-14 | 2012-05-31 | Ranbaxy Lab Ltd | Derivati pirazolo b piridina kot inhibitorji fosfodiesteraze |
US20110130403A1 (en) * | 2007-03-14 | 2011-06-02 | Ranbaxy Laboratories Limited | Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors |
EP2111861A1 (en) | 2008-04-21 | 2009-10-28 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type IV inhibitors |
JP2013537533A (ja) | 2010-07-30 | 2013-10-03 | ランバクシー ラボラトリーズ リミテッド | マトリックスメタロプロテイナーゼ阻害剤 |
CA2812319A1 (en) | 2010-09-24 | 2012-03-29 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
MD20150049A2 (ro) | 2012-12-03 | 2015-11-30 | Pfizer Inc. | Modulatori selectivi noi de receptor androgenic |
US9784726B2 (en) | 2013-01-08 | 2017-10-10 | Atrogi Ab | Screening method, a kit, a method of treatment and a compound for use in a method of treatment |
CN104557614B (zh) * | 2014-12-15 | 2017-01-04 | 广东东阳光药业有限公司 | 一种胺的还原方法 |
CN105622461B (zh) * | 2016-01-29 | 2018-06-19 | 华南理工大学 | 一种化合物及其制备方法与应用 |
CN105859589B (zh) * | 2016-04-05 | 2018-09-28 | 深圳市康立生生物科技有限公司 | 一种制备班布特罗杂质c的方法 |
GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
CN109942462B (zh) * | 2019-03-06 | 2022-01-14 | 宏冠生物药业有限公司 | 一种盐酸班布特罗的合成工艺 |
GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE178032C1 (da) | 1961-01-01 | |||
DE1643488U (de) | 1949-11-28 | 1952-09-11 | G E Hilge Fa | Brutgeraet. |
DK85789C (da) | 1955-07-05 | 1958-06-30 | Cilag Ag | Fremgangsmåde til fremstilling af d,1- eller 1-isopropyl-aminometyl-(3,4-dihydroksy-fenyl)-karbinol eller salte deraf. |
DE1768167U (de) | 1958-04-02 | 1958-06-04 | Artur O Herrmann | Warngeraet bei strassenhindernissen. |
DE1275069B (de) | 1960-02-15 | 1968-08-14 | Boehringer Sohn Ingelheim | 1-(3', 5'-Dihydroxyphenyl)-1-hydroxy-2-isopropylaminoalkane und Verfahren zu ihrer Herstellung |
NL282274A (da) | 1961-09-14 | |||
FR1324857A (fr) * | 1962-06-14 | 1963-04-19 | Chemie Linz Ag | Procédé pour la préparation de dérivés de la phényléthanolamine |
GB1141606A (en) | 1965-04-12 | 1969-01-29 | Rech S Et D Applic Scient Et M | Improvements in alkyl ethers of substituted phenylaminoethanols |
DE1543372A1 (de) | 1966-10-18 | 1971-04-01 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen |
NO132866C (da) | 1966-10-19 | 1976-01-21 | Draco Ab | |
US3937838A (en) * | 1966-10-19 | 1976-02-10 | Aktiebolaget Draco | Orally active bronchospasmolytic compounds and their preparation |
SE335359B (da) | 1966-10-19 | 1971-05-24 | Draco Ab | |
SE358633B (da) | 1966-10-19 | 1973-08-06 | Draco Ab | |
FR6087M (da) | 1967-01-10 | 1968-06-04 | ||
SE369299B (da) | 1967-10-18 | 1974-08-19 | Draco Ab | |
SE338324B (da) | 1967-12-19 | 1971-09-06 | Haessle Ab | |
NO129903B (da) | 1969-04-01 | 1974-06-10 | Sterling Drug Inc | |
AT294046B (de) | 1969-07-08 | 1971-11-10 | Chemie Linz Ag | Verfahren zur Herstellung des N,N'-Bis[2-(3',4'-dihydroxyphenyl)-2-hydroxyäthyl]-hexamethylendiamins, seiner optisch aktiven Formen und der Salze derselben |
US3657319A (en) * | 1970-05-05 | 1972-04-18 | Smith Kline French Lab | Alpha-aminoalkyl-4-hydroxy-3-carboalkoxyaminobenzyl alcohols |
NO126437B (da) | 1970-08-05 | 1973-02-05 | Draco Ab | |
NL7112938A (da) | 1970-09-30 | 1972-04-05 | ||
CH550771A (de) | 1970-10-30 | 1974-06-28 | Hoffmann La Roche | Verfahren zur herstellung von phenaethylaminderivaten. |
US3876679A (en) | 1970-12-09 | 1975-04-08 | Aldrich Chem Co Inc | Di-substituted phenethylcarbamic acid esters |
NL7213759A (da) | 1971-10-19 | 1973-04-25 | ||
US4011258A (en) | 1973-06-21 | 1977-03-08 | Aktiebolaget Draco | Orally active bronchospasmolytic compounds |
FI56673C (fi) | 1974-03-29 | 1981-02-04 | Huhtamaeki Yhthymae Oy | Nytt foerfarande foer framstaellning av alfa-tert-bytylaminometyl-4-hydroxy-m-xylen-alfa1 alfa3-diol |
JPS556625B2 (da) | 1974-05-16 | 1980-02-18 | ||
US4063025A (en) * | 1975-02-05 | 1977-12-13 | Yamanouchi Pharmaceutical Co., Ltd. | 4-Substituted amino-α-aminomethylbenzyl alcohol derivatives |
SE7510988L (sv) | 1975-10-01 | 1977-04-02 | Draco Ab | Nya farmaceutiskt aktiva foreningar |
DE2710997C3 (de) * | 1977-03-14 | 1980-08-14 | Dr. Karl Thomae Gmbh, 7950 Biberach | 4-Alkoxy carbonylamino-phenyläthanolamine, deren Herstellung und deren Verwendung als Arzneimittel |
-
1981
- 1981-06-30 CY CY1273A patent/CY1273A/xx unknown
- 1981-06-30 AT AT81850117T patent/ATE7689T1/de active
- 1981-06-30 DE DE8181850117T patent/DE3163871D1/de not_active Expired
- 1981-06-30 EP EP81850117A patent/EP0043807B1/en not_active Expired
- 1981-07-01 US US06/279,672 patent/US4419364A/en not_active Expired - Lifetime
- 1981-07-07 IE IE1522/81A patent/IE51373B1/en not_active IP Right Cessation
- 1981-07-07 NO NO812311A patent/NO152130C/no unknown
- 1981-07-07 NZ NZ197628A patent/NZ197628A/en unknown
- 1981-07-07 AU AU72618/81A patent/AU539976B2/en not_active Expired
- 1981-07-07 PH PH25872A patent/PH16535A/en unknown
- 1981-07-08 HU HU813788A patent/HU187611B/hu unknown
- 1981-07-08 PL PL1981232108A patent/PL128513B1/pl unknown
- 1981-07-08 HU HU811986A patent/HU184959B/hu unknown
- 1981-07-08 CA CA000381360A patent/CA1180021A/en not_active Expired
- 1981-07-08 ES ES503768A patent/ES8300678A1/es not_active Expired
- 1981-07-08 IS IS2657A patent/IS1262B6/is unknown
- 1981-07-08 FI FI812158A patent/FI73666C/fi not_active IP Right Cessation
- 1981-07-08 SU SU813308249A patent/SU1128830A3/ru active
- 1981-07-08 PT PT73336A patent/PT73336B/pt unknown
- 1981-07-08 CS CS815265A patent/CS221845B2/cs unknown
- 1981-07-08 DK DK303481A patent/DK157678C/da active
- 1981-07-09 KR KR1019810002490A patent/KR850000301B1/ko active
- 1981-07-09 YU YU1704/81A patent/YU42116B/xx unknown
- 1981-07-09 GR GR65453A patent/GR74291B/el unknown
- 1981-07-09 DD DD81231626A patent/DD202001A5/de unknown
-
1982
- 1982-06-15 ES ES513108A patent/ES8304072A1/es not_active Expired
- 1982-06-15 ES ES513109A patent/ES8304534A1/es not_active Expired
- 1982-07-06 US US06/395,650 patent/US4451663A/en not_active Expired - Lifetime
- 1982-07-23 PH PH27617A patent/PH19447A/en unknown
-
1983
- 1983-04-15 YU YU863/83A patent/YU43168B/xx unknown
- 1983-04-15 YU YU864/83A patent/YU43169B/xx unknown
-
1984
- 1984-09-26 KR KR1019840005925A patent/KR850000871B1/ko not_active IP Right Cessation
- 1984-09-26 KR KR1019840005924A patent/KR850000870B1/ko not_active IP Right Cessation
- 1984-11-09 SG SG797/84A patent/SG79784G/en unknown
-
1985
- 1985-01-17 HK HK53/85A patent/HK5385A/xx not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY26/87A patent/MY8700026A/xx unknown
-
1992
- 1992-06-24 MX MX9203239A patent/MX9203239A/es unknown
-
1993
- 1993-06-16 LU LU88304C patent/LU88304I2/fr unknown
-
1996
- 1996-06-27 NO NO1996008C patent/NO1996008I1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CS221845B2 (en) | Method of making the ethanolamine derivatives | |
JP2799242B2 (ja) | 抗高脂血性および抗アテローム動脈硬化性の尿素化合物 | |
PL117551B1 (en) | Process for preparing novel,optically active phenethanoloaminesaminov | |
EP0043940B1 (de) | 3,1-Benzoxazin-2-one, ihre Herstellung und Verwendung | |
EP0220878A2 (en) | Ethanolamine compounds | |
PL91560B1 (da) | ||
EP0029320A2 (en) | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions | |
NZ199215A (en) | Secondary or tertiary omega-phenylalkylamines | |
EP0608568A1 (en) | Aminocycloalkanobenzodioxoles as beta-3 selective adrenergic agents | |
US4719310A (en) | Ester and amide substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy)alkanoic acids and their salts | |
NZ202817A (en) | Morpholine carboximide or urea derivatives and pharmaceutical compositions | |
DE3634974A1 (de) | Dichloranilinderivate | |
US4556668A (en) | Ethylenediamine derivatives of aryloxypropanolamine aryl esters having various medicinal properties | |
EP0293925B1 (en) | Compound active in cardiovascular therapy | |
CS221846B2 (en) | Method of making the ethanolamine derivatives | |
SU1398771A3 (ru) | Способ получени замещенных бензамидов | |
US4084002A (en) | Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use | |
EP0196648A1 (en) | Novel diamine derivatives | |
JPS632966A (ja) | 化学中間体 | |
EP0219350A2 (en) | Ethanolamine compounds | |
US20020128209A1 (en) | Pyranoside derivatives | |
CS214706B2 (cs) | Způsob výroby R-jN-(2-fenyl-2-hydroxyethyl)-3-fenylpropylaminů | |
SI8111704A8 (sl) | Postopek za pripravo etanolaminskih derivatov | |
WO1996031466A1 (en) | New ethanolamine derivatives | |
HU209285B (hu) | Eljárás fenetanol-amin-származékok és ezeket hatóanyagként tartalmazó gyógyászati készítmények előállítására |