CS221550B2 - Method of making the 2,3-and 3,4-disubstituted tetrahydropropyrollo /1,2-a/pyrimidine,mixture thereof and salts - Google Patents

Method of making the 2,3-and 3,4-disubstituted tetrahydropropyrollo /1,2-a/pyrimidine,mixture thereof and salts Download PDF

Info

Publication number
CS221550B2
CS221550B2 CS803171A CS317180A CS221550B2 CS 221550 B2 CS221550 B2 CS 221550B2 CS 803171 A CS803171 A CS 803171A CS 317180 A CS317180 A CS 317180A CS 221550 B2 CS221550 B2 CS 221550B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
group
pyrimidine
oxo
pyrrolo
Prior art date
Application number
CS803171A
Other languages
Czech (cs)
English (en)
Inventor
Jozsef Kukusi
Istvan Hermecz
Zoltan Meszaros
Gyurgy Szasz
Lelle Vasvari
Agnes Horvath
Tibor Breining
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS221550B2 publication Critical patent/CS221550B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS803171A 1979-05-11 1980-05-06 Method of making the 2,3-and 3,4-disubstituted tetrahydropropyrollo /1,2-a/pyrimidine,mixture thereof and salts CS221550B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1930A HU176942B (hu) 1979-05-11 1979-05-11 Sposob poluchenija 2,3- i 3,4-dvuzamehhjonnykh tetragidro-pirrolo!1,2-a!-pirimidinov

Publications (1)

Publication Number Publication Date
CS221550B2 true CS221550B2 (en) 1983-04-29

Family

ID=10994745

Family Applications (1)

Application Number Title Priority Date Filing Date
CS803171A CS221550B2 (en) 1979-05-11 1980-05-06 Method of making the 2,3-and 3,4-disubstituted tetrahydropropyrollo /1,2-a/pyrimidine,mixture thereof and salts

Country Status (27)

Country Link
US (1) US4367229A (da)
JP (1) JPS565479A (da)
AR (1) AR225308A1 (da)
AU (1) AU539466B2 (da)
BE (1) BE883215A (da)
CA (1) CA1149806A (da)
CH (1) CH649551A5 (da)
CS (1) CS221550B2 (da)
DD (1) DD150612A5 (da)
DE (1) DE3017625A1 (da)
DK (1) DK152501C (da)
ES (1) ES491153A0 (da)
FI (1) FI70218C (da)
FR (1) FR2456105A1 (da)
GB (1) GB2049694B (da)
GR (1) GR68516B (da)
HU (1) HU176942B (da)
IL (1) IL59987A (da)
IT (1) IT1147735B (da)
LU (1) LU82435A1 (da)
NL (1) NL8002682A (da)
NO (1) NO155773C (da)
PL (1) PL123709B1 (da)
PT (1) PT71211A (da)
SE (1) SE437030B (da)
SU (1) SU1048986A3 (da)
YU (1) YU122080A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482557A (en) * 1979-05-11 1984-11-13 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US5344933A (en) * 1991-09-11 1994-09-06 Fuji Photo Film Co., Ltd. Pyrrole ring-or condensed pyrrole ring-containing azomethine dye
EP0971924B1 (en) 1997-01-22 2002-08-21 Ciba SC Holding AG Photoactivatable nitrogen-containing bases based on alpha-amino ketones
JP2000026465A (ja) * 1998-07-14 2000-01-25 Fuji Photo Film Co Ltd ピロロ［１，２−ａ］ピリミジン化合物及びそれを用いた感熱記録材料
US11983498B2 (en) * 2021-03-18 2024-05-14 Augmented Intelligence Technologies, Inc. System and methods for language processing of document sequences using a neural network

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1803758U (de) 1959-09-03 1960-01-07 Eugen Haller Spritz- und spanschutz -geraet.
AT299212B (de) * 1966-11-02 1972-06-12 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
DE1803785A1 (de) * 1968-10-18 1970-06-04 Hoechst Ag Verfahren zur Herstellung von 1,2-disubstituierten 6-Oxo-1.4.5.6-tetrahydropyrimidinen
BE788601A (fr) * 1971-09-10 1973-03-08 Takeda Chemical Industries Ltd Procede de preparation de derives de pyrimidine
HU167676B (da) 1972-11-29 1975-11-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
AR225308A1 (es) 1982-03-15
NL8002682A (nl) 1980-11-13
DD150612A5 (de) 1981-09-09
JPS565479A (en) 1981-01-20
DK204880A (da) 1980-11-12
GB2049694A (en) 1980-12-31
GB2049694B (en) 1983-05-18
CA1149806A (en) 1983-07-12
FR2456105B1 (da) 1984-08-10
FI801515A (fi) 1980-11-12
SU1048986A3 (ru) 1983-10-15
ES8104293A1 (es) 1981-04-16
US4367229A (en) 1983-01-04
SE437030B (sv) 1985-02-04
NO801376L (no) 1980-11-12
SE8003477L (sv) 1980-11-12
PL224124A1 (da) 1981-02-13
GR68516B (da) 1982-01-11
ES491153A0 (es) 1981-04-16
YU122080A (en) 1983-02-28
LU82435A1 (de) 1980-07-31
NO155773C (no) 1987-05-27
FI70218B (fi) 1986-02-28
AU5827680A (en) 1980-11-13
DE3017625A1 (de) 1980-11-20
AU539466B2 (en) 1984-09-27
IT1147735B (it) 1986-11-26
HU176942B (hu) 1981-06-28
IL59987A0 (en) 1980-07-31
IL59987A (en) 1984-04-30
PT71211A (en) 1980-06-01
DK152501C (da) 1988-08-08
PL123709B1 (en) 1982-11-30
BE883215A (fr) 1980-09-01
FR2456105A1 (fr) 1980-12-05
DK152501B (da) 1988-03-07
FI70218C (fi) 1986-09-15
IT8067738A0 (it) 1980-05-09
NO155773B (no) 1987-02-16
CH649551A5 (de) 1985-05-31

Similar Documents

Publication Publication Date Title
AU2003265585B2 (en) Calcium receptor modulating compound and use thereof
Lane 460. A modified benziminazole synthesis
WO2004103991A1 (fr) Piperidines 2-substituees, bibliotheque focalisee et composition pharmaceutique
CS221550B2 (en) Method of making the 2,3-and 3,4-disubstituted tetrahydropropyrollo /1,2-a/pyrimidine,mixture thereof and salts
CH396926A (de) Verfahren zur Herstellung neuer Pyrazolopyrimidine
JPH0585553B2 (da)
US3833598A (en) Amino derivatives of pyrazolopyridine-6-carboxylic acids and esters
CA1089855A (en) Derivatives of pyrazolo [1,5-a] pyrido [2,3- d]-pyrimidin-9(4h)-one
US3382245A (en) Diazaindole compounds and process for their production
FI70217C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-substituerade hexahydropyrimido/1,2-a/azepiner
Yamamoto et al. Studies of seven-membered heterocyclic compounds containing nitrogen. X. Syntheses of 5, 6, 8, 9-tetrahydro-7H-pyrimido [4, 5-d] azepines
US3155665A (en) 4, 6-dialkyl-5, 7-diketothiazolo [4, 5-d] pyrimidine-2-carboxylic acid and derivatives thereof
ES2685837T3 (es) Proceso y productos intermedios para la síntesis de derivados de (3-alquil-5-piperidin-1-il-3,3a-dihidropirazolo[1,5-a]pirimidin-7-il)-amino
US4482557A (en) 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity
Liu et al. Synthesis of pyrazolotriazolopyrimidine tri-fused heterocyclic compounds
CH641179A5 (de) Heterocyclische verbindungen mit stickstoff im ringsystem und verfahren zur herstellung derselben.
JPS62195368A (ja) ５−アミノ−１ｈ−ピラゾ−ル系化合物
CA1095907A (en) Meso-ionic didehydro derivatives of 1,7-dehydro-1- substituted -3h-pyrazolo [4,3-e]-1,2,4-triazolo [4,3-c]-pyrimidine-3-thiones and 3-ones
CZ309620B6 (cs) Způsob přípravy amidů kyseliny lysergové a jejich derivátů
Shikhaliev et al. A NEW REAGENT FOR THE SYNTHESIS OF PYRAZOLO [4, 3-e][1, 2, 4] TRIAZOLO [1, 5-c] PYRIMIDINES
Gubaidullin et al. Tautomerism of Aza heterocycles: V. Structure of the spontaneous transformation products of 5-methyl-2-phenyl-3, 3a, 4, 5, 6, 7-hexahydro-2 H-pyrazolo-[4, 3-c] pyridin-3-one in crystal and solution
CN104829604A (zh) 用于分离和纯化核苷的方法以及获得的核苷
Breining et al. Nitrogen bridgehead compounds, part 49. Synthesis and stereochemistry of 9-aminotetrahydro-4 H-pyrido [1, 2-a] pyrimidin-4-ones.
Bergmann et al. Methylation of Purin-8-ones