CS205041B2 - Process for preparing 2-hydroxymethyl-3-hydroxy-6-/1-hydroxy-2-terc.butylaminomethyl/pyridine - Google Patents

Process for preparing 2-hydroxymethyl-3-hydroxy-6-/1-hydroxy-2-terc.butylaminomethyl/pyridine Download PDF

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Publication number
CS205041B2
CS205041B2 CS765863A CS586376A CS205041B2 CS 205041 B2 CS205041 B2 CS 205041B2 CS 765863 A CS765863 A CS 765863A CS 586376 A CS586376 A CS 586376A CS 205041 B2 CS205041 B2 CS 205041B2
Authority
CS
Czechoslovakia
Prior art keywords
hydroxy
hydroxymethyl
formula
pyridine
maleate
Prior art date
Application number
CS765863A
Other languages
Czech (cs)
English (en)
Inventor
Ronnie D Carroll
James R Tretter
Bernard S Moore
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS205041B2 publication Critical patent/CS205041B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS765863A 1975-10-03 1976-09-09 Process for preparing 2-hydroxymethyl-3-hydroxy-6-/1-hydroxy-2-terc.butylaminomethyl/pyridine CS205041B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/619,302 US4011231A (en) 1975-10-03 1975-10-03 2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate

Publications (1)

Publication Number Publication Date
CS205041B2 true CS205041B2 (en) 1981-04-30

Family

ID=24481329

Family Applications (2)

Application Number Title Priority Date Filing Date
CS765863A CS205041B2 (en) 1975-10-03 1976-09-09 Process for preparing 2-hydroxymethyl-3-hydroxy-6-/1-hydroxy-2-terc.butylaminomethyl/pyridine
CS765863A CS205042B2 (en) 1975-10-03 1976-09-09 Method of producing salt of 2-phenyl-6-/1-hydroxy-2-tertiary butyl-amino-ethyl/-4h-pyrido/3,2-d/-1,3-dioxine with maleic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS765863A CS205042B2 (en) 1975-10-03 1976-09-09 Method of producing salt of 2-phenyl-6-/1-hydroxy-2-tertiary butyl-amino-ethyl/-4h-pyrido/3,2-d/-1,3-dioxine with maleic acid

Country Status (30)

Country Link
US (1) US4011231A (el)
JP (1) JPS5246081A (el)
AR (1) AR213180A1 (el)
AT (1) AT353789B (el)
BE (1) BE846471A (el)
BG (1) BG27544A3 (el)
CA (1) CA1059518A (el)
CH (1) CH616424A5 (el)
CS (2) CS205041B2 (el)
DD (2) DD133672A5 (el)
DE (1) DE2640123C3 (el)
DK (1) DK147049C (el)
ES (2) ES451746A1 (el)
FI (1) FI64354C (el)
FR (1) FR2326191A1 (el)
GB (1) GB1510075A (el)
GR (1) GR61628B (el)
HU (2) HU177493B (el)
IE (1) IE43503B1 (el)
LU (1) LU75898A1 (el)
NL (1) NL164274C (el)
NO (1) NO147027C (el)
PH (1) PH14511A (el)
PL (1) PL106863B1 (el)
PT (1) PT65619B (el)
RO (1) RO69886A (el)
SE (2) SE428127B (el)
SU (2) SU673168A3 (el)
YU (1) YU39545B (el)
ZA (1) ZA765253B (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477671A (en) * 1981-02-09 1984-10-16 Pfizer Inc. 3-Acetoxy or benzyloxy-2-acetoxymethyl-6-[1-acetoxy-2-(N-tert-butylacetamido)ethyl]pyridine intermediates
US4632992A (en) * 1981-02-09 1986-12-30 Pfizer Inc. Intermediates for preparing pirbuterol and analogs
US5395939A (en) * 1993-11-30 1995-03-07 North Carolina State University Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3250778A (en) * 1962-11-29 1966-05-10 Hoffmann La Roche Intermediates for and synthesis of vitamin b and related compounds
US3700681A (en) * 1971-02-16 1972-10-24 Pfizer 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)pyridines

Also Published As

Publication number Publication date
AU1788376A (en) 1978-03-16
GB1510075A (en) 1978-05-10
BE846471A (fr) 1977-03-23
NO147027B (no) 1982-10-11
SU725562A3 (ru) 1980-03-30
IE43503L (en) 1977-04-03
HU172998B (hu) 1979-01-28
BG27544A3 (en) 1979-11-12
JPS5246081A (en) 1977-04-12
PH14511A (en) 1981-08-24
NL7610683A (nl) 1977-04-05
ES451746A1 (es) 1977-08-16
FR2326191B1 (el) 1978-11-17
FI64354B (fi) 1983-07-29
ZA765253B (en) 1977-08-31
DE2640123C3 (de) 1980-09-25
PL106863B1 (pl) 1980-01-31
LU75898A1 (el) 1977-05-11
FR2326191A1 (fr) 1977-04-29
PT65619A (en) 1976-10-01
DE2640123A1 (de) 1977-04-07
SE7609497L (sv) 1977-04-04
CA1059518A (en) 1979-07-31
JPS5519210B2 (el) 1980-05-24
CS205042B2 (en) 1981-04-30
SE8003311L (sv) 1980-04-30
DK147049C (da) 1984-10-01
DK147049B (da) 1984-03-26
FI64354C (fi) 1983-11-10
YU39545B (en) 1984-12-31
NO763307L (el) 1977-04-05
ES457257A1 (es) 1978-02-01
DD133672A5 (de) 1979-01-17
DE2640123B2 (de) 1980-01-31
SU673168A3 (ru) 1979-07-05
NL164274C (nl) 1980-12-15
IE43503B1 (en) 1981-03-11
HU177493B (en) 1981-10-28
RO69886A (ro) 1981-09-24
FI762693A (el) 1977-04-04
YU216576A (en) 1982-06-30
DK434176A (da) 1977-04-04
SE437159B (sv) 1985-02-11
PT65619B (en) 1978-04-05
GR61628B (en) 1978-12-04
AR213180A1 (es) 1978-12-29
ATA692376A (de) 1979-05-15
SE428127B (sv) 1983-06-06
AT353789B (de) 1979-12-10
NO147027C (no) 1983-01-19
DD129325A5 (de) 1978-01-11
CH616424A5 (el) 1980-03-31
NL164274B (nl) 1980-07-15
US4011231A (en) 1977-03-08

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