CS199726B2 - Method of producing 7 beta-halogenaryl-malonamido-7-alpha-methoxy-3-heterocyclylthiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid and derivatives of the same - Google Patents

Method of producing 7 beta-halogenaryl-malonamido-7-alpha-methoxy-3-heterocyclylthiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid and derivatives of the same Download PDF

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Publication number
CS199726B2
CS199726B2 CS782774A CS277478A CS199726B2 CS 199726 B2 CS199726 B2 CS 199726B2 CS 782774 A CS782774 A CS 782774A CS 277478 A CS277478 A CS 277478A CS 199726 B2 CS199726 B2 CS 199726B2
Authority
CS
Czechoslovakia
Prior art keywords
ester
formula
compounds
acid
het
Prior art date
Application number
CS782774A
Other languages
Czech (cs)
English (en)
Inventor
Yoshio Hamashima
Masayuki Narisada
Original Assignee
Hayashi Sadao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52049630A external-priority patent/JPS609717B2/ja
Priority claimed from JP52102260A external-priority patent/JPS6031835B2/ja
Application filed by Hayashi Sadao filed Critical Hayashi Sadao
Publication of CS199726B2 publication Critical patent/CS199726B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CS782774A 1977-04-28 1978-04-28 Method of producing 7 beta-halogenaryl-malonamido-7-alpha-methoxy-3-heterocyclylthiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid and derivatives of the same CS199726B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52049630A JPS609717B2 (ja) 1977-04-28 1977-04-28 ハロアリ―ルマロンアミドオキサセフアロスポリン
JP52102260A JPS6031835B2 (ja) 1977-08-25 1977-08-25 チアジアゾリルチオオキサセフアロスポリン

Publications (1)

Publication Number Publication Date
CS199726B2 true CS199726B2 (en) 1980-07-31

Family

ID=26390044

Family Applications (1)

Application Number Title Priority Date Filing Date
CS782774A CS199726B2 (en) 1977-04-28 1978-04-28 Method of producing 7 beta-halogenaryl-malonamido-7-alpha-methoxy-3-heterocyclylthiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid and derivatives of the same

Country Status (29)

Country Link
US (1) US4183928A (es)
AR (1) AR227614A1 (es)
AT (1) AT357674B (es)
AU (1) AU522851B2 (es)
BG (1) BG34337A3 (es)
CA (1) CA1100962A (es)
CH (1) CH640535A5 (es)
CS (1) CS199726B2 (es)
DD (1) DD135908A5 (es)
DE (1) DE2818985C2 (es)
DK (1) DK182878A (es)
ES (1) ES469206A1 (es)
FI (1) FI63410C (es)
FR (1) FR2388815A1 (es)
GB (1) GB1574273A (es)
GR (1) GR69966B (es)
HU (1) HU178105B (es)
IE (1) IE46627B1 (es)
IL (1) IL54596A0 (es)
IT (1) IT1111469B (es)
MX (1) MX5952E (es)
NL (1) NL189669C (es)
NO (1) NO158506C (es)
NZ (1) NZ187086A (es)
PH (1) PH16851A (es)
PL (1) PL110680B1 (es)
PT (1) PT67957B (es)
SU (1) SU784779A3 (es)
YU (1) YU42477B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259485A (en) * 1979-04-24 1981-03-31 Eli Lilly And Company Crystallization process
JPS60123490A (ja) * 1983-12-07 1985-07-02 Shionogi & Co Ltd マロニルオキサセフェムカルボン酸誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178005C (nl) * 1972-11-06 1986-01-02 Merck & Co Inc Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum.
GB1510794A (en) * 1974-08-06 1978-05-17 Univ Kingston 1-oxacephems and intermediates therefor
US4045438A (en) * 1975-10-24 1977-08-30 Yeda Research And Development Co. Ltd. Cephalosporin antibiotics
US4048311A (en) * 1976-01-08 1977-09-13 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins

Also Published As

Publication number Publication date
IE46627B1 (en) 1983-08-10
NL7804628A (nl) 1978-10-31
PT67957A (en) 1978-05-01
DD135908A5 (de) 1979-06-06
IE780844L (en) 1978-10-25
NO158506C (no) 1988-09-21
HU178105B (en) 1982-03-28
FR2388815B1 (es) 1982-06-18
NL189669C (nl) 1993-06-16
FI781313A (fi) 1978-10-29
IT1111469B (it) 1986-01-13
YU42477B (en) 1988-10-31
NL189669B (nl) 1993-01-18
DE2818985C2 (de) 1995-08-17
CA1100962A (en) 1981-05-12
NO781502L (no) 1978-10-31
MX5952E (es) 1984-09-06
US4183928A (en) 1980-01-15
AU3552778A (en) 1979-11-01
AT357674B (de) 1980-07-25
NO158506B (no) 1988-06-13
PH16851A (en) 1984-03-19
GR69966B (es) 1982-07-22
BG34337A3 (en) 1983-08-15
NZ187086A (en) 1981-05-15
IT7867986A0 (it) 1978-04-28
FI63410C (fi) 1983-06-10
PL206451A1 (pl) 1979-04-09
FI63410B (fi) 1983-02-28
AR227614A1 (es) 1982-11-30
SU784779A3 (ru) 1980-11-30
CH640535A5 (de) 1984-01-13
FR2388815A1 (fr) 1978-11-24
YU103578A (en) 1983-06-30
DK182878A (da) 1978-10-29
IL54596A0 (en) 1978-07-31
PT67957B (en) 1980-03-05
ES469206A1 (es) 1979-09-16
AU522851B2 (en) 1982-07-01
DE2818985A1 (de) 1978-11-02
GB1574273A (en) 1980-09-03
ATA311378A (de) 1979-12-15
PL110680B1 (en) 1980-07-31

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