CO5540369A2 - Perfil farmococinetico mejorado de sustancias hidrofobas - Google Patents

Perfil farmococinetico mejorado de sustancias hidrofobas

Info

Publication number
CO5540369A2
CO5540369A2 CO03112352A CO03112352A CO5540369A2 CO 5540369 A2 CO5540369 A2 CO 5540369A2 CO 03112352 A CO03112352 A CO 03112352A CO 03112352 A CO03112352 A CO 03112352A CO 5540369 A2 CO5540369 A2 CO 5540369A2
Authority
CO
Colombia
Prior art keywords
hydrophobic substance
hydrophobic substances
dermis
administration
improved hydrophobic
Prior art date
Application number
CO03112352A
Other languages
English (en)
Inventor
Thomas C Pinkerton
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of CO5540369A2 publication Critical patent/CO5540369A2/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01GCOMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00Compounds of titanium
    • C01G23/04Oxides; Hydroxides
    • C01G23/047Titanium dioxide
    • C01G23/053Producing by wet processes, e.g. hydrolysing titanium salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/46Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on titanium oxides or titanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Psychology (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Environmental & Geological Engineering (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Geology (AREA)
  • Structural Engineering (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

2.- Un dispositivo para administrar a un mamífero una sustancia hidrófoba, el dispositivo está configurado para administración de la sustancia hidrófoba en la dermis para obtener absorción sistémica de la sustancia hidrófoba, en donde el dispositivo es un sistema de inyección de electroporación o un sistema de inyección de poración térmica.3.- Un equipo para administración a la dermis de un mamífero, el equipo comprende una sustancia hidrófoba, en donde después de administración de la sustancia hidrófoba a la dermis, se produce una absorción sistémica mejorada con relación a la absorción producida después de inyectar la sustancia hidrófoba subcutáneamente.
CO03112352A 2001-06-29 2003-12-24 Perfil farmococinetico mejorado de sustancias hidrofobas CO5540369A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/897,801 US20030073609A1 (en) 2001-06-29 2001-06-29 Enhanced pharmacokinetic profile of intradermally delivered substances

Publications (1)

Publication Number Publication Date
CO5540369A2 true CO5540369A2 (es) 2005-07-29

Family

ID=25408438

Family Applications (2)

Application Number Title Priority Date Filing Date
CO03112342A CO5640074A2 (es) 2001-06-29 2003-12-24 Agonistas de dopamina hidrofobicos administrados a la dermis
CO03112352A CO5540369A2 (es) 2001-06-29 2003-12-24 Perfil farmococinetico mejorado de sustancias hidrofobas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CO03112342A CO5640074A2 (es) 2001-06-29 2003-12-24 Agonistas de dopamina hidrofobicos administrados a la dermis

Country Status (17)

Country Link
US (4) US20030073609A1 (es)
EP (3) EP1399205A2 (es)
JP (3) JP2004537540A (es)
KR (3) KR20040022438A (es)
CN (3) CN1610567A (es)
AU (1) AU2002345813B2 (es)
BR (2) BR0210688A (es)
CA (3) CA2450354A1 (es)
CO (2) CO5640074A2 (es)
CZ (3) CZ20033059A3 (es)
EA (3) EA006922B1 (es)
IL (3) IL158651A0 (es)
MX (3) MXPA03011931A (es)
NO (3) NO20035580D0 (es)
PL (3) PL365667A1 (es)
WO (3) WO2003002175A2 (es)
ZA (3) ZA200308385B (es)

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Also Published As

Publication number Publication date
CA2450354A1 (en) 2003-01-09
US20040170654A1 (en) 2004-09-02
IL159025A0 (en) 2004-05-12
CN1522139A (zh) 2004-08-18
KR20040019024A (ko) 2004-03-04
CZ20033364A3 (cs) 2004-08-18
IL158651A0 (en) 2004-05-12
CZ20033363A3 (cs) 2004-09-15
CA2452321A1 (en) 2003-01-09
CN1723052A (zh) 2006-01-18
NO20035782L (no) 2004-02-24
EP1416915A1 (en) 2004-05-12
NO20035731L (no) 2004-02-27
WO2003002094A8 (en) 2005-10-20
NO20035731D0 (no) 2003-12-19
EA200301307A1 (ru) 2004-06-24
ZA200309125B (en) 2004-11-24
ZA200309151B (en) 2004-11-25
KR20040022438A (ko) 2004-03-12
IL159024A0 (en) 2004-05-12
EP1399205A2 (en) 2004-03-24
EA006578B1 (ru) 2006-02-24
MXPA03011710A (es) 2004-12-06
MXPA03011794A (es) 2005-03-07
NO20035580D0 (no) 2003-12-15
JP2005502613A (ja) 2005-01-27
WO2003002175A8 (en) 2003-07-10
CZ20033059A3 (cs) 2004-04-14
WO2003002094A2 (en) 2003-01-09
JP2005503359A (ja) 2005-02-03
WO2003002103A3 (en) 2003-04-10
CN1610567A (zh) 2005-04-27
US20030073609A1 (en) 2003-04-17
PL366370A1 (en) 2005-01-24
JP2004537540A (ja) 2004-12-16
CO5640074A2 (es) 2006-05-31
WO2003002103A2 (en) 2003-01-09
CA2452393A1 (en) 2003-01-09
PL366635A1 (en) 2005-02-07
BR0210665A (pt) 2004-10-05
EA006922B1 (ru) 2006-04-28
US20040175401A1 (en) 2004-09-09
EA200301309A1 (ru) 2004-12-30
MXPA03011931A (es) 2005-03-07
EP1399206A2 (en) 2004-03-24
EA006961B1 (ru) 2006-06-30
KR20040029327A (ko) 2004-04-06
ZA200308385B (en) 2004-10-28
WO2003002175A2 (en) 2003-01-09
US20040028707A1 (en) 2004-02-12
AU2002345813B2 (en) 2006-10-26
PL365667A1 (en) 2005-01-10
WO2003002175A3 (en) 2003-03-20
EA200301308A1 (ru) 2004-08-26
BR0210688A (pt) 2004-09-21

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