NO20035731L - Forbedret farmakokinetisk profil av hydrofobe substanser - Google Patents
Forbedret farmakokinetisk profil av hydrofobe substanserInfo
- Publication number
- NO20035731L NO20035731L NO20035731A NO20035731A NO20035731L NO 20035731 L NO20035731 L NO 20035731L NO 20035731 A NO20035731 A NO 20035731A NO 20035731 A NO20035731 A NO 20035731A NO 20035731 L NO20035731 L NO 20035731L
- Authority
- NO
- Norway
- Prior art keywords
- pharmacokinetic profile
- improved pharmacokinetic
- hydrophobic substances
- mammal
- substance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G23/00—Compounds of titanium
- C01G23/04—Oxides; Hydroxides
- C01G23/047—Titanium dioxide
- C01G23/053—Producing by wet processes, e.g. hydrolysing titanium salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
- B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
- C04B35/46—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on titanium oxides or titanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Radiology & Medical Imaging (AREA)
- Manufacturing & Machinery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ceramic Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- General Life Sciences & Earth Sciences (AREA)
- Psychology (AREA)
- Structural Engineering (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Environmental & Geological Engineering (AREA)
- Materials Engineering (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Metode for systemisk administrering av en hydrofob substans til et pattedyr beskrives. Metoden omfatter avlevering av den hydrofobe substansen til dermis hos pattedyret hvormed en forbedret systemisk absorpsjon oppnås sammenlignet med den absorpsjon som oppnås ved av levering av substansen subkutant ved bolusadministrering.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/897,801 US20030073609A1 (en) | 2001-06-29 | 2001-06-29 | Enhanced pharmacokinetic profile of intradermally delivered substances |
PCT/US2002/020080 WO2003002094A2 (en) | 2001-06-29 | 2002-06-24 | Enhanced pharmacokinetic profile of hydrophobic substances |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20035731D0 NO20035731D0 (no) | 2003-12-19 |
NO20035731L true NO20035731L (no) | 2004-02-27 |
Family
ID=25408438
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20035580A NO20035580D0 (no) | 2001-06-29 | 2003-12-15 | Forsterket systemisk absorpsjon av intradermalt avleverte substanser |
NO20035731A NO20035731L (no) | 2001-06-29 | 2003-12-19 | Forbedret farmakokinetisk profil av hydrofobe substanser |
NO20035782A NO20035782L (no) | 2001-06-29 | 2003-12-22 | Forbedret farmakokinetisk profil for hydrofobe dopaminagonister |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20035580A NO20035580D0 (no) | 2001-06-29 | 2003-12-15 | Forsterket systemisk absorpsjon av intradermalt avleverte substanser |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20035782A NO20035782L (no) | 2001-06-29 | 2003-12-22 | Forbedret farmakokinetisk profil for hydrofobe dopaminagonister |
Country Status (17)
Country | Link |
---|---|
US (4) | US20030073609A1 (no) |
EP (3) | EP1399205A2 (no) |
JP (3) | JP2004537540A (no) |
KR (3) | KR20040022438A (no) |
CN (3) | CN1610567A (no) |
AU (1) | AU2002345813B2 (no) |
BR (2) | BR0210665A (no) |
CA (3) | CA2450354A1 (no) |
CO (2) | CO5540369A2 (no) |
CZ (3) | CZ20033059A3 (no) |
EA (3) | EA006922B1 (no) |
IL (3) | IL158651A0 (no) |
MX (3) | MXPA03011931A (no) |
NO (3) | NO20035580D0 (no) |
PL (3) | PL365667A1 (no) |
WO (3) | WO2003002175A2 (no) |
ZA (3) | ZA200308385B (no) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1048725B1 (en) | 1999-04-27 | 2005-07-06 | Transgene S.A. | Process for production of mammalian cell lines |
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
US8465468B1 (en) | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
US20020156453A1 (en) * | 1999-10-14 | 2002-10-24 | Pettis Ronald J. | Method and device for reducing therapeutic dosage |
US20050008683A1 (en) * | 2000-06-29 | 2005-01-13 | Becton Dickinson And Company | Method for delivering interferons to the intradermal compartment |
US20040175360A1 (en) * | 2000-06-29 | 2004-09-09 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
DE10066158B4 (de) * | 2000-08-24 | 2007-08-09 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms |
DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
MXPA03009371A (es) * | 2001-04-13 | 2004-11-12 | Becton Dickinson Co | Metodos y dispositivos para administrar sustancias en la capa intradermica de la piel para absorcion sistemica. |
WO2003002069A2 (en) * | 2001-06-29 | 2003-01-09 | Becton, Dickinson And Company | Intradermal delivery of vaccines and gene therapeutic agents via microcannula |
US20030073609A1 (en) * | 2001-06-29 | 2003-04-17 | Pinkerton Thomas C. | Enhanced pharmacokinetic profile of intradermally delivered substances |
US20050010193A1 (en) * | 2002-05-06 | 2005-01-13 | Laurent Philippe E. | Novel methods for administration of drugs and devices useful thereof |
US20040120964A1 (en) * | 2001-10-29 | 2004-06-24 | Mikszta John A. | Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses |
US20060264886A9 (en) * | 2002-05-06 | 2006-11-23 | Pettis Ronald J | Method for altering insulin pharmacokinetics |
BR0311443A (pt) * | 2002-05-06 | 2005-03-22 | Becton Dickinson Co | Método e dispositivo para controlar farmacocinética de droga |
JP2005537054A (ja) * | 2002-08-30 | 2005-12-08 | ベクトン・ディキンソン・アンド・カンパニー | 免疫調節化合物の薬物動態を制御する方法 |
JP4599296B2 (ja) * | 2002-10-11 | 2010-12-15 | ベクトン・ディキンソン・アンド・カンパニー | 単一針または多針皮内(id)送達装置に結合されたフィードバックまたはモデルベースコントローラを使用して患者の体内の物質の濃度の連続長期制御を開始し維持するためのシステムおよび方法 |
WO2005016401A2 (en) * | 2003-06-13 | 2005-02-24 | Becton Dickinson And Company | Improved intra-dermal delivery of biologically active agents |
AU2003282780A1 (en) | 2003-08-08 | 2005-03-07 | Abgenix, Inc. | Antibodies directed to parathyroid hormone (pth) and uses thereof |
US7318925B2 (en) | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
BR122020015610B8 (pt) | 2003-08-12 | 2023-11-14 | Becton Dickinson Co | Dispositivo para distribuir um medicamento para dentro do corpo de um paciente por injeção |
WO2005023328A2 (en) * | 2003-08-26 | 2005-03-17 | Becton Dickinson And Company | Methods for intradermal delivery of therapeutics agents |
WO2005091922A2 (en) * | 2004-03-03 | 2005-10-06 | Becton, Dickinson And Company | Methods and devices for improving delivery of a substance to skin |
US20050256182A1 (en) * | 2004-05-11 | 2005-11-17 | Sutter Diane E | Formulations of anti-pain agents and methods of using the same |
JP5037496B2 (ja) * | 2005-05-13 | 2012-09-26 | トラスティーズ オブ ボストン ユニバーシティ | 1型糖尿病用の完全自動制御システム |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
US8025634B1 (en) * | 2006-09-18 | 2011-09-27 | Baxter International Inc. | Method and system for controlled infusion of therapeutic substances |
US8622991B2 (en) | 2007-03-19 | 2014-01-07 | Insuline Medical Ltd. | Method and device for drug delivery |
CN101678169A (zh) * | 2007-03-19 | 2010-03-24 | 茵苏莱恩医药有限公司 | 药物输送设备 |
US9220837B2 (en) | 2007-03-19 | 2015-12-29 | Insuline Medical Ltd. | Method and device for drug delivery |
EP2136863A2 (en) * | 2007-03-19 | 2009-12-30 | Insuline Medical Ltd. | Device for drug delivery and associated connections thereto |
WO2008115586A1 (en) * | 2007-03-21 | 2008-09-25 | Alza Corporation | Apparatus and method for transdermal delivery of a triptan agonist |
US8642062B2 (en) | 2007-10-31 | 2014-02-04 | Abbott Cardiovascular Systems Inc. | Implantable device having a slow dissolving polymer |
ATE542521T1 (de) * | 2007-11-29 | 2012-02-15 | Alltranz Inc | Verfahren und zusammensetzungen zur verstärkung der lebensfähigkeit von mikronadelporen |
US8409133B2 (en) | 2007-12-18 | 2013-04-02 | Insuline Medical Ltd. | Drug delivery device with sensor for closed-loop operation |
WO2010052579A2 (en) | 2008-11-07 | 2010-05-14 | Insuline Medical Ltd. | Device and method for drug delivery |
US7828996B1 (en) | 2009-03-27 | 2010-11-09 | Abbott Cardiovascular Systems Inc. | Method for the manufacture of stable, nano-sized particles |
US9199034B2 (en) * | 2009-11-09 | 2015-12-01 | Becton, Dickinson And Company | Drug delivery devices, systems, and methods |
KR100967900B1 (ko) * | 2010-04-12 | 2010-07-06 | 대전광역시 | 교차로 정보제공 시스템 |
EP2627292B1 (en) | 2010-10-15 | 2018-10-10 | Clearside Biomedical, Inc. | Device for ocular access |
CA2816314C (en) | 2010-10-31 | 2018-03-06 | Trustees Of Boston University | Blood glucose control system |
SG11201503637SA (en) | 2012-11-08 | 2015-06-29 | Clearside Biomedical Inc | Methods and devices for the treatment of ocular diseases in human subjects |
CN105246529B (zh) | 2013-05-03 | 2019-06-14 | 科尼尔赛德生物医学公司 | 用于眼部注射的设备和方法 |
EP3003454B1 (en) | 2013-06-03 | 2020-01-08 | Clearside Biomedical, Inc. | Apparatus for drug delivery using multiple reservoirs |
CN106456064B (zh) | 2014-01-31 | 2020-11-27 | 波士顿大学董事会 | 基于在前时期的离线葡萄糖控制 |
WO2015196085A2 (en) | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
CN107847437B (zh) * | 2015-05-28 | 2024-03-26 | 瑞迪博士实验室有限公司 | 用于治疗疼痛的塞来昔布口服组合物 |
WO2017027459A1 (en) | 2015-08-07 | 2017-02-16 | Trustees Of Boston University | Glucose control system with automatic adaptation of glucose target |
US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
WO2017192565A1 (en) | 2016-05-02 | 2017-11-09 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
WO2018031913A1 (en) | 2016-08-12 | 2018-02-15 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
EP4000075A4 (en) | 2019-07-16 | 2023-10-04 | Beta Bionics, Inc. | BLOOD GLUCOSE CONTROL SYSTEM |
US11957876B2 (en) | 2019-07-16 | 2024-04-16 | Beta Bionics, Inc. | Glucose control system with automated backup therapy protocol generation |
CA3146965A1 (en) | 2019-07-16 | 2021-02-21 | Beta Bionics, Inc. | Blood glucose control system |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2619962A (en) * | 1948-02-19 | 1952-12-02 | Res Foundation | Vaccination appliance |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
US4270537A (en) * | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
IE53703B1 (en) * | 1982-12-13 | 1989-01-18 | Elan Corp Plc | Drug delivery device |
US4826689A (en) | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
CA1283827C (en) * | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
US6056716A (en) * | 1987-06-08 | 2000-05-02 | D'antonio Consultants International Inc. | Hypodermic fluid dispenser |
AU614092B2 (en) * | 1987-09-11 | 1991-08-22 | Paul Max Grinwald | Improved method and apparatus for enhanced drug permeation of skin |
IT1227626B (it) | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
US5273975A (en) * | 1989-06-09 | 1993-12-28 | The Upjohn Company | Heterocyclic amines having central nervous system activity |
US5098389A (en) * | 1990-06-28 | 1992-03-24 | Becton, Dickinson And Company | Hypodermic needle assembly |
US5527288A (en) * | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
TW279133B (no) * | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
US5156591A (en) * | 1990-12-13 | 1992-10-20 | S. I. Scientific Innovations Ltd. | Skin electrode construction and transdermal drug delivery device utilizing same |
US5279544A (en) * | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
SE9102652D0 (sv) * | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
US5346702A (en) | 1992-12-04 | 1994-09-13 | Sterling Winthrop Inc. | Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization |
US5298262A (en) | 1992-12-04 | 1994-03-29 | Sterling Winthrop Inc. | Use of ionic cloud point modifiers to prevent particle aggregation during sterilization |
US5336507A (en) | 1992-12-11 | 1994-08-09 | Sterling Winthrop Inc. | Use of charged phospholipids to reduce nanoparticle aggregation |
US5279552A (en) * | 1993-01-11 | 1994-01-18 | Anton Magnet | Intradermal injection device |
CA2132277C (en) * | 1993-10-22 | 2005-05-10 | Giorgio Cirelli | Injection device |
US5997501A (en) | 1993-11-18 | 1999-12-07 | Elan Corporation, Plc | Intradermal drug delivery device |
US5591139A (en) * | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
US5582591A (en) * | 1994-09-02 | 1996-12-10 | Delab | Delivery of solid drug compositions |
IE72524B1 (en) * | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US5983130A (en) * | 1995-06-07 | 1999-11-09 | Alza Corporation | Electrotransport agent delivery method and apparatus |
US5801057A (en) * | 1996-03-22 | 1998-09-01 | Smart; Wilson H. | Microsampling device and method of construction |
US6576636B2 (en) * | 1996-05-22 | 2003-06-10 | Protarga, Inc. | Method of treating a liver disorder with fatty acid-antiviral agent conjugates |
HUP0002102A3 (en) * | 1996-06-10 | 2001-02-28 | Elan Corp Plc | Needle for subcutaneous delivery of fluids |
US5871158A (en) * | 1997-01-27 | 1999-02-16 | The University Of Utah Research Foundation | Methods for preparing devices having metallic hollow microchannels on planar substrate surfaces |
US5783705A (en) * | 1997-04-28 | 1998-07-21 | Texas Biotechnology Corporation | Process of preparing alkali metal salys of hydrophobic sulfonamides |
US5928207A (en) * | 1997-06-30 | 1999-07-27 | The Regents Of The University Of California | Microneedle with isotropically etched tip, and method of fabricating such a device |
IE970782A1 (en) * | 1997-10-22 | 1999-05-05 | Elan Corp | An improved automatic syringe |
US5957895A (en) * | 1998-02-20 | 1999-09-28 | Becton Dickinson And Company | Low-profile automatic injection device with self-emptying reservoir |
US6347247B1 (en) * | 1998-05-08 | 2002-02-12 | Genetronics Inc. | Electrically induced vessel vasodilation |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
EP1086214B1 (en) * | 1998-06-10 | 2009-11-25 | Georgia Tech Research Corporation | Microneedle devices and methods of their manufacture |
US6589987B2 (en) * | 1998-09-08 | 2003-07-08 | Charlotte-Mecklenburg Hospital Authority | Method of treating cancer using tetraethyl thiuram disulfide |
US6455564B1 (en) | 1999-01-06 | 2002-09-24 | Pharmacia & Upjohn Company | Method of treating sexual disturbances |
AU5461300A (en) * | 1999-06-04 | 2000-12-28 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
DE19938823A1 (de) * | 1999-08-19 | 2001-02-22 | Boehringer Ingelheim Pharma | Medikamentöse Behandlung des Restless Leg Syndroms |
US6319224B1 (en) * | 1999-08-20 | 2001-11-20 | Bioject Medical Technologies Inc. | Intradermal injection system for injecting DNA-based injectables into humans |
US7113821B1 (en) * | 1999-08-25 | 2006-09-26 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery |
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
US6569143B2 (en) * | 1999-10-14 | 2003-05-27 | Becton, Dickinson And Company | Method of intradermally injecting substances |
US6843781B2 (en) * | 1999-10-14 | 2005-01-18 | Becton, Dickinson And Company | Intradermal needle |
US6776776B2 (en) * | 1999-10-14 | 2004-08-17 | Becton, Dickinson And Company | Prefillable intradermal delivery device |
AU3440601A (en) * | 1999-11-24 | 2001-06-04 | Elan Pharmaceuticals, Inc. | Method and composition for protecting against radio-contrast medium-induced renal dysfunction |
DE10001785A1 (de) * | 2000-01-18 | 2001-07-19 | Boehringer Ingelheim Pharma | NK¶1¶-Rezeptor-Antagonisten zur Behandlung des Restless Legs Syndroms |
WO2003002069A2 (en) * | 2001-06-29 | 2003-01-09 | Becton, Dickinson And Company | Intradermal delivery of vaccines and gene therapeutic agents via microcannula |
US20030073609A1 (en) * | 2001-06-29 | 2003-04-17 | Pinkerton Thomas C. | Enhanced pharmacokinetic profile of intradermally delivered substances |
-
2001
- 2001-06-29 US US09/897,801 patent/US20030073609A1/en not_active Abandoned
- 2001-12-26 IL IL15865101A patent/IL158651A0/xx unknown
- 2001-12-26 CN CNA018234062A patent/CN1610567A/zh active Pending
- 2001-12-26 EP EP01991616A patent/EP1399205A2/en not_active Withdrawn
- 2001-12-26 CA CA002450354A patent/CA2450354A1/en not_active Abandoned
- 2001-12-26 JP JP2003508413A patent/JP2004537540A/ja not_active Withdrawn
- 2001-12-26 WO PCT/US2001/050862 patent/WO2003002175A2/en not_active Application Discontinuation
- 2001-12-26 EA EA200301307A patent/EA006922B1/ru not_active IP Right Cessation
- 2001-12-26 MX MXPA03011931A patent/MXPA03011931A/es not_active Application Discontinuation
- 2001-12-26 PL PL01365667A patent/PL365667A1/xx not_active Application Discontinuation
- 2001-12-26 CZ CZ20033059A patent/CZ20033059A3/cs unknown
- 2001-12-26 KR KR10-2003-7017079A patent/KR20040022438A/ko not_active Application Discontinuation
-
2002
- 2002-06-24 WO PCT/US2002/020080 patent/WO2003002094A2/en active Search and Examination
- 2002-06-24 CZ CZ20033364A patent/CZ20033364A3/cs unknown
- 2002-06-24 CA CA002452393A patent/CA2452393A1/en not_active Abandoned
- 2002-06-24 CA CA002452321A patent/CA2452321A1/en not_active Abandoned
- 2002-06-24 PL PL02366370A patent/PL366370A1/xx unknown
- 2002-06-24 AU AU2002345813A patent/AU2002345813B2/en not_active Expired - Fee Related
- 2002-06-24 IL IL15902502A patent/IL159025A0/xx unknown
- 2002-06-24 JP JP2003508342A patent/JP2005502613A/ja not_active Withdrawn
- 2002-06-24 BR BR0210665-5A patent/BR0210665A/pt not_active IP Right Cessation
- 2002-06-24 EP EP02753349A patent/EP1416915A1/en not_active Ceased
- 2002-06-24 US US10/480,973 patent/US20040170654A1/en not_active Abandoned
- 2002-06-24 CN CNA028130502A patent/CN1723052A/zh active Pending
- 2002-06-24 EP EP02744560A patent/EP1399206A2/en not_active Withdrawn
- 2002-06-24 EA EA200301308A patent/EA006578B1/ru not_active IP Right Cessation
- 2002-06-24 CZ CZ20033363A patent/CZ20033363A3/cs unknown
- 2002-06-24 JP JP2003508333A patent/JP2005503359A/ja not_active Withdrawn
- 2002-06-24 IL IL15902402A patent/IL159024A0/xx unknown
- 2002-06-24 PL PL02366635A patent/PL366635A1/xx not_active Application Discontinuation
- 2002-06-24 BR BR0210688-4A patent/BR0210688A/pt not_active IP Right Cessation
- 2002-06-24 WO PCT/US2002/019918 patent/WO2003002103A2/en not_active Application Discontinuation
- 2002-06-24 KR KR10-2003-7017082A patent/KR20040019024A/ko not_active Application Discontinuation
- 2002-06-24 EA EA200301309A patent/EA006961B1/ru unknown
- 2002-06-24 KR KR10-2003-7017081A patent/KR20040029327A/ko not_active Application Discontinuation
- 2002-06-24 MX MXPA03011794A patent/MXPA03011794A/es unknown
- 2002-06-24 US US10/480,975 patent/US20040175401A1/en not_active Abandoned
- 2002-06-24 MX MXPA03011710A patent/MXPA03011710A/es unknown
- 2002-06-24 CN CNA028131746A patent/CN1522139A/zh active Pending
-
2003
- 2003-05-22 US US10/443,361 patent/US20040028707A1/en not_active Abandoned
- 2003-10-28 ZA ZA200308385A patent/ZA200308385B/en unknown
- 2003-11-24 ZA ZA200309125A patent/ZA200309125B/en unknown
- 2003-11-25 ZA ZA200309151A patent/ZA200309151B/en unknown
- 2003-12-15 NO NO20035580A patent/NO20035580D0/no not_active Application Discontinuation
- 2003-12-19 NO NO20035731A patent/NO20035731L/no not_active Application Discontinuation
- 2003-12-22 NO NO20035782A patent/NO20035782L/no not_active Application Discontinuation
- 2003-12-24 CO CO03112352A patent/CO5540369A2/es not_active Application Discontinuation
- 2003-12-24 CO CO03112342A patent/CO5640074A2/es not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20035731L (no) | Forbedret farmakokinetisk profil av hydrofobe substanser | |
EP2025356A3 (en) | A method of using a syringe mount of medical fluid injector | |
ATE442862T2 (de) | Niederviskose konzentrierte proteinformulierungen | |
NO20054555D0 (no) | Farmasoytiske preparater som omfatter syrestabilisert insulin | |
IS7043A (is) | Lyfjagjöf efnafræðilega umbreytts insúlíns í lungu | |
AR029139A1 (es) | Interleuquina 2 estabilizada | |
BR0106103A (pt) | Bomba de infusão, motor de bomba papa mover fluido através de uma câmara de fluido de um corpo cilìndrico de seringa, método para infusão de um fluido em um paciente, e, bomba de infusão ambulatorial | |
IS6719A (is) | Aðferð til verkjadeyfingar | |
NO20003050D0 (no) | Metode for Õ administrere monomere insulinanaloger | |
DK1151004T3 (da) | Fremgangsmåde til fremstilling af IL-1RA, et terapeutisk protein, ud fra legemsvæsker | |
WO2006020255A3 (en) | Apparatus and methods for treating tissue using passive injection systems | |
WO2006054280A3 (en) | System and method for delivering fluid into flexible biological barrier | |
PA8621201A1 (es) | Composicion farmaceutica apta la comprension directa para la administracion oral de cci-779 | |
WO2005025646A3 (en) | System and method for providing servo-controlled resuscitation | |
IS8060A (is) | Truflanaþolið skammtaform til íkomu um húð sem inniheldur virkan efnisþátt og andstæðan efnisþátt við fjarhlið virka efnislagsins | |
DE60219307D1 (de) | Oral anzuwendende arzneizusammensetzung enthaltend ein statinderivat | |
DE602006001759D1 (de) | Verbinderanordnung, Stangenhaltesystem und Verfahren | |
IS7097A (is) | Lyfjablanda til að gefa fúlvestrant í vöðva | |
DK1274429T3 (da) | Topiske formuleringer til transdermal indgivelse af niacin-prolægemidler samt metoder til behandling af hyperlipidæmi | |
WO2006138236A3 (en) | Method and apparatus for bubble injection of agent into exhaust gas for use with emission abatement device | |
EA200600402A1 (ru) | Клеточные стенки дрожжей для лечения или профилактики гипергликемии или для стабилизации уровня сахара в крови | |
DK2359854T3 (da) | Farmaceutiske sammensætninger og fremgangsmåder egnet til modulering af angiogenese | |
ATE381907T1 (de) | Kanüle zum applizieren von medizinischen stoffen | |
WO2005013327A3 (en) | Regulation of flow of processing chemistry only into a processing chamber | |
WO2001072292A3 (en) | Vitamin d compounds used to stabilize kidney transplants |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |