NO20035731L - Forbedret farmakokinetisk profil av hydrofobe substanser - Google Patents

Forbedret farmakokinetisk profil av hydrofobe substanser

Info

Publication number
NO20035731L
NO20035731L NO20035731A NO20035731A NO20035731L NO 20035731 L NO20035731 L NO 20035731L NO 20035731 A NO20035731 A NO 20035731A NO 20035731 A NO20035731 A NO 20035731A NO 20035731 L NO20035731 L NO 20035731L
Authority
NO
Norway
Prior art keywords
pharmacokinetic profile
improved pharmacokinetic
hydrophobic substances
mammal
substance
Prior art date
Application number
NO20035731A
Other languages
English (en)
Other versions
NO20035731D0 (no
Inventor
Thomas Pinkerton
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of NO20035731D0 publication Critical patent/NO20035731D0/no
Publication of NO20035731L publication Critical patent/NO20035731L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00—Compounds of titanium
    • C01G23/04—Oxides; Hydroxides
    • C01G23/047—Titanium dioxide
    • C01G23/053—Producing by wet processes, e.g. hydrolysing titanium salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/46—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on titanium oxides or titanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Nanotechnology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Ceramic Engineering (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Environmental & Geological Engineering (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Geology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Metode for systemisk administrering av en hydrofob substans til et pattedyr beskrives. Metoden omfatter avlevering av den hydrofobe substansen til dermis hos pattedyret hvormed en forbedret systemisk absorpsjon oppnås sammenlignet med den absorpsjon som oppnås ved av levering av substansen subkutant ved bolusadministrering.
NO20035731A 2001-06-29 2003-12-19 Forbedret farmakokinetisk profil av hydrofobe substanser NO20035731L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/897,801 US20030073609A1 (en) 2001-06-29 2001-06-29 Enhanced pharmacokinetic profile of intradermally delivered substances
PCT/US2002/020080 WO2003002094A2 (en) 2001-06-29 2002-06-24 Enhanced pharmacokinetic profile of hydrophobic substances

Publications (2)

Publication Number Publication Date
NO20035731D0 NO20035731D0 (no) 2003-12-19
NO20035731L true NO20035731L (no) 2004-02-27

Family

ID=25408438

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20035580A NO20035580D0 (no) 2001-06-29 2003-12-15 Forsterket systemisk absorpsjon av intradermalt avleverte substanser
NO20035731A NO20035731L (no) 2001-06-29 2003-12-19 Forbedret farmakokinetisk profil av hydrofobe substanser
NO20035782A NO20035782L (no) 2001-06-29 2003-12-22 Forbedret farmakokinetisk profil for hydrofobe dopaminagonister

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20035580A NO20035580D0 (no) 2001-06-29 2003-12-15 Forsterket systemisk absorpsjon av intradermalt avleverte substanser

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20035782A NO20035782L (no) 2001-06-29 2003-12-22 Forbedret farmakokinetisk profil for hydrofobe dopaminagonister

Country Status (17)

Country Link
US (4) US20030073609A1 (no)
EP (3) EP1399205A2 (no)
JP (3) JP2004537540A (no)
KR (3) KR20040022438A (no)
CN (3) CN1610567A (no)
AU (1) AU2002345813B2 (no)
BR (2) BR0210665A (no)
CA (3) CA2450354A1 (no)
CO (2) CO5540369A2 (no)
CZ (3) CZ20033059A3 (no)
EA (3) EA006922B1 (no)
IL (3) IL158651A0 (no)
MX (3) MXPA03011931A (no)
NO (3) NO20035580D0 (no)
PL (3) PL365667A1 (no)
WO (3) WO2003002175A2 (no)
ZA (3) ZA200308385B (no)

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Publication number Publication date
CO5540369A2 (es) 2005-07-29
EP1399206A2 (en) 2004-03-24
CA2450354A1 (en) 2003-01-09
EA200301307A1 (ru) 2004-06-24
US20040175401A1 (en) 2004-09-09
IL158651A0 (en) 2004-05-12
US20040170654A1 (en) 2004-09-02
MXPA03011931A (es) 2005-03-07
KR20040019024A (ko) 2004-03-04
EA006922B1 (ru) 2006-04-28
EA006961B1 (ru) 2006-06-30
WO2003002103A3 (en) 2003-04-10
PL365667A1 (en) 2005-01-10
EP1399205A2 (en) 2004-03-24
BR0210665A (pt) 2004-10-05
US20030073609A1 (en) 2003-04-17
ZA200309125B (en) 2004-11-24
ZA200309151B (en) 2004-11-25
IL159025A0 (en) 2004-05-12
BR0210688A (pt) 2004-09-21
PL366635A1 (en) 2005-02-07
CZ20033364A3 (cs) 2004-08-18
WO2003002103A2 (en) 2003-01-09
EP1416915A1 (en) 2004-05-12
CA2452321A1 (en) 2003-01-09
KR20040029327A (ko) 2004-04-06
CA2452393A1 (en) 2003-01-09
CZ20033059A3 (cs) 2004-04-14
NO20035782L (no) 2004-02-24
WO2003002175A8 (en) 2003-07-10
CN1610567A (zh) 2005-04-27
PL366370A1 (en) 2005-01-24
KR20040022438A (ko) 2004-03-12
CZ20033363A3 (cs) 2004-09-15
EA200301309A1 (ru) 2004-12-30
NO20035580D0 (no) 2003-12-15
WO2003002175A2 (en) 2003-01-09
WO2003002094A2 (en) 2003-01-09
CO5640074A2 (es) 2006-05-31
EA200301308A1 (ru) 2004-08-26
NO20035731D0 (no) 2003-12-19
CN1723052A (zh) 2006-01-18
CN1522139A (zh) 2004-08-18
US20040028707A1 (en) 2004-02-12
EA006578B1 (ru) 2006-02-24
JP2005503359A (ja) 2005-02-03
WO2003002175A3 (en) 2003-03-20
JP2004537540A (ja) 2004-12-16
IL159024A0 (en) 2004-05-12
WO2003002094A8 (en) 2005-10-20
ZA200308385B (en) 2004-10-28
AU2002345813B2 (en) 2006-10-26
JP2005502613A (ja) 2005-01-27
MXPA03011710A (es) 2004-12-06
MXPA03011794A (es) 2005-03-07

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