CO5050367A1 - Nueva composicion - Google Patents

Nueva composicion

Info

Publication number
CO5050367A1
CO5050367A1 CO99025940A CO99025940A CO5050367A1 CO 5050367 A1 CO5050367 A1 CO 5050367A1 CO 99025940 A CO99025940 A CO 99025940A CO 99025940 A CO99025940 A CO 99025940A CO 5050367 A1 CO5050367 A1 CO 5050367A1
Authority
CO
Colombia
Prior art keywords
vaccine composition
composition according
per
new composition
hav
Prior art date
Application number
CO99025940A
Other languages
English (en)
Inventor
Claude Artois
Michael J Clark
Clothilde Thiriart
Thoelen Stefan Gabriel Jozef
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of CO5050367A1 publication Critical patent/CO5050367A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32411Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Una composición de vacuna acuosa que comprende 0,015-0,1 mgde fosfato de aluminio por µg de antígeno de superficie de la hepatitis B.Una composición de vacuna según la reivindicación 1, que comprende además un virus de la hepatitis A (HAV) inactivado.Una composición de vacuna según la reivindicación 2, que comprende además hidróxido de aluminio. Una composición de vacuna según la reivindicación 3, que comprende 0,05-0,10 mg de hidróxido de aluminio por ml.Una composición de vacuna según cualquiera de las reivindicaciones anteriores, que comprende además formaldehído.Una composición de vacuna según la reivindicación 5, en la que la concentración de formaldehído varía de aproximadamente 10-200 µg por ml.Una vacuna según cualquiera de las reivindicaciones 2 a 6, en la que la concentración de HAV varía de aproximadamente 720-2880 EU por ml.
CO99025940A 1998-05-01 1999-04-29 Nueva composicion CO5050367A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9809507.8A GB9809507D0 (en) 1998-05-01 1998-05-01 Novel composition

Publications (1)

Publication Number Publication Date
CO5050367A1 true CO5050367A1 (es) 2001-06-27

Family

ID=10831426

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99025940A CO5050367A1 (es) 1998-05-01 1999-04-29 Nueva composicion

Country Status (29)

Country Link
EP (1) EP1073462B1 (es)
JP (2) JP5138843B2 (es)
KR (1) KR100612547B1 (es)
CN (1) CN1263509C (es)
AR (1) AR016987A1 (es)
AT (1) ATE345815T1 (es)
AU (1) AU743759B2 (es)
BR (1) BR9910157A (es)
CA (1) CA2331086C (es)
CO (1) CO5050367A1 (es)
CY (1) CY1107322T1 (es)
CZ (1) CZ301232B6 (es)
DE (1) DE69934108T2 (es)
DK (1) DK1073462T3 (es)
ES (1) ES2277437T3 (es)
GB (1) GB9809507D0 (es)
GC (1) GC0000101A (es)
HK (1) HK1034202A1 (es)
HU (1) HU228209B1 (es)
IL (1) IL139269A0 (es)
MY (1) MY128929A (es)
NO (1) NO20005483L (es)
NZ (1) NZ507902A (es)
PL (1) PL190729B1 (es)
PT (1) PT1073462E (es)
TR (1) TR200003235T2 (es)
TW (1) TW553744B (es)
WO (1) WO1999056772A2 (es)
ZA (1) ZA200006118B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1513555A (zh) * 2003-07-31 2004-07-21 长春生物制品研究所 甲-乙型肝炎联合疫苗及其冻干制剂
EP1862176A1 (de) * 2006-05-31 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
EP1862177A1 (de) * 2006-06-01 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
CN102198270B (zh) * 2011-05-16 2012-06-27 大连汉信生物制药有限公司 一种含铝佐剂乙肝疫苗的制备方法
KR101281098B1 (ko) * 2011-06-30 2013-07-02 주식회사 녹십자 B형 간염 바이러스 표면 항원상의 에피토프 및 이의 용도
CN102988975A (zh) * 2012-11-30 2013-03-27 深圳康泰生物制品股份有限公司 甲型、乙型肝炎联合疫苗及其制备方法
US9849066B2 (en) 2013-04-24 2017-12-26 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0349686A (ja) * 1989-07-11 1991-03-04 Smithkline Biologicals Sa レトロウイルスgag蛋白の真核生物細胞における発現
ATE168271T1 (de) * 1992-05-23 1998-08-15 Smithkline Beecham Biolog Kombinierte impfstoffe, die hepatitis b oberfläche antigen und andere antigenen enthalten
GB9503863D0 (en) * 1995-02-25 1995-04-19 Smithkline Beecham Biolog Vaccine compositions
EP0845270B1 (en) * 1996-03-23 2004-10-27 The Research Foundation For Microbial Diseases Of Osaka University Functional fragment antigen of tetanus toxin and tetanus vaccine

Also Published As

Publication number Publication date
TR200003235T2 (tr) 2001-03-21
NZ507902A (en) 2002-03-28
CZ20004061A3 (cs) 2001-04-11
PL344137A1 (en) 2001-10-08
CN1263509C (zh) 2006-07-12
CY1107322T1 (el) 2012-11-21
HUP0101652A1 (hu) 2001-09-28
JP2010209118A (ja) 2010-09-24
CA2331086C (en) 2010-06-22
BR9910157A (pt) 2001-01-09
NO20005483D0 (no) 2000-10-31
EP1073462B1 (en) 2006-11-22
EP1073462A2 (en) 2001-02-07
ATE345815T1 (de) 2006-12-15
DK1073462T3 (da) 2007-02-26
WO1999056772A2 (en) 1999-11-11
CA2331086A1 (en) 1999-11-11
MY128929A (en) 2007-02-28
ES2277437T3 (es) 2007-07-01
HU228209B1 (en) 2013-01-28
ZA200006118B (en) 2002-01-30
JP5138843B2 (ja) 2013-02-06
HK1034202A1 (en) 2001-10-19
DE69934108D1 (de) 2007-01-04
CZ301232B6 (cs) 2009-12-16
IL139269A0 (en) 2001-11-25
KR20010043224A (ko) 2001-05-25
AR016987A1 (es) 2001-08-01
PT1073462E (pt) 2007-01-31
KR100612547B1 (ko) 2006-08-11
DE69934108T2 (de) 2007-04-19
HUP0101652A3 (en) 2004-10-28
AU743759B2 (en) 2002-02-07
CN1308547A (zh) 2001-08-15
TW553744B (en) 2003-09-21
NO20005483L (no) 2000-12-08
GB9809507D0 (en) 1998-07-01
WO1999056772A3 (en) 2000-02-03
AU4137999A (en) 1999-11-23
GC0000101A (en) 2005-06-29
PL190729B1 (pl) 2005-12-30
JP2002513771A (ja) 2002-05-14

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