CO4820394A1 - Preparados farmaceuticos que contienen acidos difosfonicos para la aplicacion por via oral - Google Patents

Preparados farmaceuticos que contienen acidos difosfonicos para la aplicacion por via oral

Info

Publication number
CO4820394A1
CO4820394A1 CO97017783A CO97017783A CO4820394A1 CO 4820394 A1 CO4820394 A1 CO 4820394A1 CO 97017783 A CO97017783 A CO 97017783A CO 97017783 A CO97017783 A CO 97017783A CO 4820394 A1 CO4820394 A1 CO 4820394A1
Authority
CO
Colombia
Prior art keywords
poly
derivatives
active substance
active
oral application
Prior art date
Application number
CO97017783A
Other languages
English (en)
Spanish (es)
Inventor
Jorn Muckel
Heinrich Woog
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7791961&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4820394(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of CO4820394A1 publication Critical patent/CO4820394A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CO97017783A 1996-04-20 1997-04-08 Preparados farmaceuticos que contienen acidos difosfonicos para la aplicacion por via oral CO4820394A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19615812A DE19615812A1 (de) 1996-04-20 1996-04-20 Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation

Publications (1)

Publication Number Publication Date
CO4820394A1 true CO4820394A1 (es) 1999-07-28

Family

ID=7791961

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97017783A CO4820394A1 (es) 1996-04-20 1997-04-08 Preparados farmaceuticos que contienen acidos difosfonicos para la aplicacion por via oral

Country Status (26)

Country Link
US (2) US6143326A (enExample)
EP (2) EP1658852B1 (enExample)
JP (2) JP5037746B2 (enExample)
CN (1) CN101152160A (enExample)
AR (2) AR006652A1 (enExample)
AT (1) ATE404207T1 (enExample)
AU (1) AU722516B2 (enExample)
BR (1) BR9708785A (enExample)
CA (1) CA2251886C (enExample)
CO (1) CO4820394A1 (enExample)
CZ (1) CZ297341B6 (enExample)
DE (2) DE19615812A1 (enExample)
DK (1) DK0936913T4 (enExample)
ES (1) ES2313735T5 (enExample)
HU (1) HU228389B1 (enExample)
IL (2) IL163930A0 (enExample)
NO (1) NO319162B1 (enExample)
NZ (1) NZ332314A (enExample)
PA (1) PA8427301A1 (enExample)
PL (2) PL191910B1 (enExample)
PT (1) PT936913E (enExample)
RU (1) RU2193881C2 (enExample)
SI (1) SI0936913T2 (enExample)
TR (1) TR199802108T2 (enExample)
WO (1) WO1997039755A1 (enExample)
ZA (1) ZA973331B (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19615812A1 (de) * 1996-04-20 1997-10-23 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
RU2193880C2 (ru) * 1997-06-11 2002-12-10 Дзе Проктер Энд Гэмбл Компани Покрытая пленкой таблетка улучшенной безопасности для верхних отделов желудочно-кишечного тракта
EP0998932A1 (de) 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
AR024462A1 (es) * 1999-07-01 2002-10-02 Merck & Co Inc Tabletas farmaceuticas
US7674480B2 (en) * 2000-06-23 2010-03-09 Teva Pharmaceutical Industries Ltd. Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition
US6881420B2 (en) * 2000-06-23 2005-04-19 Teva Pharmaceutical Industries Ltd. Compositions and dosage forms for gastric delivery of irinotecan and methods of treatment that use it to inhibit cancer cell proliferation
US6476006B2 (en) * 2000-06-23 2002-11-05 Teva Pharmaceutical Industries, Ltd. Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates
AU2001271055B2 (en) * 2000-07-17 2005-07-07 Astellas Pharma Inc. Pharmaceutical composition improved in peroral absorbability
JP2002332235A (ja) * 2001-02-01 2002-11-22 Riderway Corp 骨疾患治療用液体医薬組成物
AR034199A1 (es) * 2001-02-01 2004-02-04 Riderway Corp Composicion farmacologica liquida para el tratamiento de enfermedades oseas y procedimientos para su elaboracion
BR0209360A (pt) * 2001-05-02 2004-06-08 Novartis Ag Método de administração de bisfosfonatos por inalação no tratamento ou prevenção de reabsorção óssea e osteoporose
BR0206441A (pt) * 2001-12-19 2003-12-30 Astrazeneca Ab Composição de revestimento de pelìcula, revestimento de pelìcula cobrindo um núcleo farmacêutico, formulação farmacêutica de liberação modificada, e, processos para preparar uma composição de revestimento de pelìcula, um revestimento de pelìcula e uma formulação
NZ532994A (en) * 2001-12-21 2008-05-30 Procter & Gamble Method for the treatment of bone disorders using a bisphosphonate regimen, risedronate in particular
MXPA04008164A (es) 2002-02-21 2005-05-17 Biovail Lab Inc Formas de dosificacion de liberacion controlada.
CA2481142C (en) * 2002-05-10 2012-11-13 F.Hoffmann-La Roche Ag Bisphosphonic acids for the treatment and prevention of osteoporosis
GB0229258D0 (en) * 2002-12-16 2003-01-22 Boots Healthcare Int Ltd Medicinal compositions
NZ555514A (en) * 2002-12-20 2008-12-24 Hoffmann La Roche High dose ibandronate formulation
TR200300510A2 (tr) * 2003-04-18 2004-11-22 Sanovel �La� Sanay� Ve T�Caret A.�. Dağılan alendronat mikropartikül formülasyonu
RU2262923C2 (ru) * 2003-12-25 2005-10-27 Государственное образовательное учреждение высшего профессионального образования Курский государственный медицинский университет Министерства здравоохранения Российской Федерации Иммобилизованная форма доксорубицина
GB0403628D0 (en) * 2004-02-18 2004-03-24 Arrow Group Ltd Compression-coated tablets and the manufacture thereof
US20080286359A1 (en) * 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US7645459B2 (en) * 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
US20080287400A1 (en) * 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US7645460B2 (en) * 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of risedronate
US8012949B2 (en) * 2004-10-08 2011-09-06 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS
WO2006039721A2 (en) * 2004-10-08 2006-04-13 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases
US20070191315A1 (en) * 2006-02-16 2007-08-16 Bengt Bergstrom Method for administering ibandronate
EP2001486A4 (en) * 2006-03-17 2010-12-29 Univ Illinois BIPHOSPHONATE COMPOUNDS AND CORRESPONDING METHODS
CN101495101B (zh) * 2006-07-25 2012-02-29 兴和株式会社 糖衣制剂及其制造方法
GB0616794D0 (en) 2006-08-24 2006-10-04 Arrow Int Ltd Solid dosage form
US20080139514A1 (en) * 2006-11-29 2008-06-12 Subhash Pandurang Gore Diphosphonic acid pharmaceutical compositions
CA2570949A1 (en) * 2006-12-12 2008-06-12 Apotex Pharmachem Inc. Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
WO2009075601A1 (fr) * 2007-12-12 2009-06-18 Alexander Valerievich Melnik Moyen d'indication d'une éventuelle prédisposition de chats à une maladie (variantes) et procédé de détermination de troubles de la santé chez les chats
EP2210596A1 (en) 2009-01-22 2010-07-28 Laboratorios Liconsa, S.A. Pharmaceutical composition of ibandronate sodium salt or a hydrate thereof
CN103079596B (zh) * 2010-08-31 2015-08-19 东丽株式会社 药物固体制剂用的包衣剂、药物用膜制剂以及包覆药物固体制剂
CA2839494C (en) * 2011-06-17 2018-11-06 Evonik Roehm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
RU2485957C1 (ru) * 2012-03-16 2013-06-27 Государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия последипломного образования" Министерства здравоохранения Российской Федерации (ГБОУ ДПО РМАПО Минздрава России) Средство для лечения низкообменного варианта заболевания скелета у больных с хронической почечной недостаточностью

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE965825C (de) 1949-10-30 1957-06-19 Walter Kloepfer Dipl Ing Dr In Zur Antennenebene senkrecht polarisierter Strahler
US4820698A (en) * 1985-11-04 1989-04-11 The Procter & Gamble Company Antimicrobial agents and process for their manufacture
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US5098717A (en) * 1987-12-09 1992-03-24 Thames Pharmacal Co., Inc. Method of treatment for pruritus
PH27186A (en) * 1989-09-07 1993-04-16 Ciba Geigy Ag Double-coated granules of disodium pamidronate
EP0550385A1 (de) * 1991-12-19 1993-07-07 Ciba-Geigy Ag Peroral zu verabreichende pharmazeutische Zusammensetzungen, die Methandiphosphonsäure-Derivate und 18-Krone-6 Ether enthalten
TW237386B (enExample) * 1992-04-15 1995-01-01 Ciba Geigy
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
RU2134103C1 (ru) * 1993-05-15 1999-08-10 Берингер Маннхайм ГмбХ Таблетка с улучшенной биодоступностью биологически активного вещества и вещество, повышающее биодоступность
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
TW390813B (en) * 1994-04-29 2000-05-21 Merck & Co Inc Wet granulation formulation for bisphosphonic acids
DE19615812A1 (de) 1996-04-20 1997-10-23 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
US5803321A (en) * 1996-11-12 1998-09-08 Randy Hangers, Lll Hanger with ganging element
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery

Also Published As

Publication number Publication date
TR199802108T2 (xx) 1999-01-18
NO319162B1 (no) 2005-06-27
BR9708785A (pt) 1999-08-03
JP5557989B2 (ja) 2014-07-23
PL191363B1 (pl) 2006-05-31
ES2313735T5 (es) 2012-12-07
DK0936913T4 (da) 2012-11-19
ES2313735T3 (es) 2009-03-01
CZ297341B6 (cs) 2006-11-15
PT936913E (pt) 2008-09-25
WO1997039755A1 (de) 1997-10-30
HU228389B1 (en) 2013-03-28
HUP9903407A2 (hu) 2000-04-28
JP2000508673A (ja) 2000-07-11
CN101152160A (zh) 2008-04-02
NO984881L (no) 1998-10-19
RU2193881C2 (ru) 2002-12-10
AU2638297A (en) 1997-11-12
PA8427301A1 (es) 2002-07-30
AR054350A2 (es) 2007-06-20
JP2008285500A (ja) 2008-11-27
CA2251886C (en) 2008-06-17
EP0936913A1 (de) 1999-08-25
SI0936913T2 (sl) 2012-11-30
EP1658852B1 (de) 2016-11-09
HUP9903407A3 (en) 2000-11-28
AR006652A1 (es) 1999-09-08
DE19615812A1 (de) 1997-10-23
ZA973331B (en) 1998-10-19
NO984881D0 (no) 1998-10-19
AU722516B2 (en) 2000-08-03
JP5037746B2 (ja) 2012-10-03
EP0936913B2 (de) 2012-09-19
IL163930A0 (en) 2005-12-18
IL126655A0 (en) 1999-08-17
PL329347A1 (en) 1999-03-29
US6143326A (en) 2000-11-07
ATE404207T1 (de) 2008-08-15
IL126655A (en) 2004-12-15
PL191910B1 (pl) 2006-07-31
CA2251886A1 (en) 1997-10-30
EP1658852A1 (de) 2006-05-24
EP0936913B1 (de) 2008-08-13
CZ336498A3 (cs) 2000-01-12
US20050089573A1 (en) 2005-04-28
DK0936913T3 (da) 2008-10-20
NZ332314A (en) 2000-03-27
SI0936913T1 (sl) 2008-12-31
DE59712959D1 (de) 2008-09-25

Similar Documents

Publication Publication Date Title
CO4820394A1 (es) Preparados farmaceuticos que contienen acidos difosfonicos para la aplicacion por via oral
KR960007517B1 (ko) 증가된 활성 물질 유동성을 지닌 경피 치료 시스템 및 그 제조방법
RU98120909A (ru) Фармацевтический препарат для орального применения, содержащий ибандронат
ES2313797T7 (es) Composición de liberación modificada multiparticulada de fenidato de metilo
JPH0315477A (ja) 活性成分としてフィゾステイグミンを有する皮膚経由医薬及びその製造方法
ATE227136T1 (de) Mittel zur verstaerkten aufnahme polarer arzneistoffe aus dem kolon
Adamson et al. Pharmacokinetics of all-trans-retinoic acid administered on an intermittent schedule.
KR870003778A (ko) 신규 약제의 제조방법
DE3363321D1 (en) Long-lasting three layered pharmaceutical film preparations
Ebrahimi et al. Effect of ferric sulfate contamination on the bonding effectiveness of etch-and-rinse and self-etch adhesives to superficial dentin
AU1534699A (en) Osmotic dosage form comprising first and second coats
JPH0794384B2 (ja) 徐放性口腔内用製剤
SV2004001556A (es) Preparaciones acidas de insulina con establidad mejorada
NO891680L (no) Osmotisk kontinuerlig avgivende oralt avgivelsessystem inneholdende et farmasoeytisk akseptabelt aktivt middel som har forbedrede kjernemembran-adhesjonsegenskaper.
DE60038536D1 (de) Matrixsystem mit verzögerter freisetzung für hochlösliche wirkstoffe
ATE202931T1 (de) Taxanderivate enthaltende arzneizubereitungen
ATE211649T1 (de) Dosisform mit gesteuerter freigabe für kalium
RU2344810C2 (ru) Новый состав для мягких желатиновых капсул, содержащих ретиноид
KR100458337B1 (ko) 치아 미백 부착제
PT90308A (pt) Processo para a preparacao de composicoes farmaceuticas contendo azelastina com libertacao controlada da substancia activa
JPH04288016A (ja) 活性型ビタミンd3類軟カプセル剤の製造方法
HUP9700842A1 (hu) Hatóanyagok szabályozott felszabadulását biztosító, stabilizált lipofil mátrixalapú gyógyászati készítmények
DE69634080D1 (de) Mittel zur verhinderung der truebung der vorderen linsenkapsel
Swift Jr Immediate dentin sealing for indirect bonded restorations
DK0450123T3 (da) Farmaceutisk præparat til topisk administration indeholdende dichlofenac-natrium