CN1774257A - 制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法 - Google Patents

制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法 Download PDF

Info

Publication number
CN1774257A
CN1774257A CNA2003801095973A CN200380109597A CN1774257A CN 1774257 A CN1774257 A CN 1774257A CN A2003801095973 A CNA2003801095973 A CN A2003801095973A CN 200380109597 A CN200380109597 A CN 200380109597A CN 1774257 A CN1774257 A CN 1774257A
Authority
CN
China
Prior art keywords
madecassoside
terminoside
mixture
extract
asiaticoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2003801095973A
Other languages
English (en)
Chinese (zh)
Inventor
A·卢瓦索
G·塞内
E·特龙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Consumer Care AG
Original Assignee
Bayer Consumer Care AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Consumer Care AG filed Critical Bayer Consumer Care AG
Publication of CN1774257A publication Critical patent/CN1774257A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Birds (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2003801095973A 2002-12-10 2003-12-10 制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法 Pending CN1774257A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0215613 2002-12-10
FR0215613A FR2848117B1 (fr) 2002-12-10 2002-12-10 Procede de preparation d'un extrait de centella asiatica riche en madecassoside et en terminoloside

Publications (1)

Publication Number Publication Date
CN1774257A true CN1774257A (zh) 2006-05-17

Family

ID=32320170

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2003801095973A Pending CN1774257A (zh) 2002-12-10 2003-12-10 制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法

Country Status (12)

Country Link
US (3) US7402669B2 (https=)
EP (1) EP1569672B1 (https=)
JP (1) JP4643275B2 (https=)
KR (2) KR20110132629A (https=)
CN (1) CN1774257A (https=)
AT (1) ATE439852T1 (https=)
AU (1) AU2003296799A1 (https=)
CA (1) CA2509421C (https=)
DE (1) DE60328912D1 (https=)
ES (1) ES2329568T3 (https=)
FR (1) FR2848117B1 (https=)
WO (1) WO2004062678A1 (https=)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101323637B (zh) * 2008-07-29 2010-12-22 卢照凯 一种积雪草甙及其制备方法
CN101407536B (zh) * 2008-11-27 2011-05-18 浙江大学 一种溶剂结晶法制备高纯度积雪草苷的工艺
CN102367263A (zh) * 2011-11-11 2012-03-07 上海师范大学 一种分离纯化积雪草三萜酸单葡萄糖苷的方法
CN103124560A (zh) * 2010-09-09 2013-05-29 纳图瑞克斯有限公司 制备积雪草提取物的方法
CN105168051A (zh) * 2015-09-16 2015-12-23 任海锋 肤色遮盖液
CN105267056A (zh) * 2015-12-01 2016-01-27 江苏隆力奇生物科技股份有限公司 一种具有抗皱祛皱功能的护肤化妆品组合物及其应用
CN107412235A (zh) * 2017-06-28 2017-12-01 上海交通大学 一种积雪草中促进pc12细胞分化的单体组合及其应用
CN107903296A (zh) * 2017-11-29 2018-04-13 陶坤秀 羟基积雪草苷的提取方法
CN111285916A (zh) * 2020-02-14 2020-06-16 浏阳朗林生物科技有限公司 一种积雪草总苷含量高的积雪草提取物的制备方法
CN112773806A (zh) * 2019-11-06 2021-05-11 鲁南制药集团股份有限公司 包含淫羊藿苷元和羟基积雪草酸的药物组合物的医药用途
CN116407478A (zh) * 2023-05-11 2023-07-11 杭州以息互联网科技有限公司 一种温和的祛痘组合物及其应用
CN116583260A (zh) * 2020-12-17 2023-08-11 欧莱雅 包含氨基酸和两种特定酸的两相化妆品组合物

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006012015A2 (en) * 2004-06-29 2006-02-02 Oregon Health And Science University Methods and compositions for nerve regeneration
FR2888114B1 (fr) * 2005-07-07 2009-10-30 Oreal Utilisation cosmetique du madecassoside et/ou du terminoloside comme agent empechant ou reduisant l'adhesion des microorganismes sur la surface de la peau et/ou des muqueuses
KR20080065641A (ko) * 2005-11-09 2008-07-14 바이엘 컨수머 케어 악티엔게젤샤프트 센텔라 아시아티카로부터의 화합물의 용도
ATE495749T1 (de) * 2007-02-12 2011-02-15 Indus Biotech Private Ltd Zusammensetzung für selektive hemmung der serotoninwiederaufnahme und verfahren dafür
BRPI0700767B8 (pt) * 2007-02-15 2021-05-25 Ache Laboratorios Farmaceuticos Sa composição farmacêutica, produto farmaceutico, processo para obtenção de compostos farmaceuticos e uso de tais compostos para o tratamento do vitiligo
FR2914857B1 (fr) * 2007-04-12 2011-01-21 Dermathologiques D Uriage Lab Compositions anti-inflammatoires et leur utilisation en cosmetique et/ou en dermatologie
WO2008142619A1 (en) * 2007-05-17 2008-11-27 Izun Pharmaceuticals Corporation Use of herbal compositions in the protection and enhancement of extracellular matrix components
EP2231139B1 (en) * 2008-01-11 2015-02-25 Shanghai Institute of Pharmaceutical Industry Therapeutic formulations based on asiatic acid and selected salts thereof
FR2929117B1 (fr) 2008-03-28 2010-05-07 Oreal Utilisation de l'association du 2,4-diaminopyrimidine 3-n-oxyde et du madecassosside et/ou du terminoloside pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
FR2929118B1 (fr) 2008-03-28 2010-05-07 Oreal Utilisation de l'association de madecassoside et/ou de terminoloside et d'une arginine pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
US8591961B2 (en) 2008-09-04 2013-11-26 Allergan, Inc. Aesthetic treatment of scars and aging skin
US8071139B2 (en) * 2008-09-04 2011-12-06 Alan David Widgerow Treatment of damaged skin
FR2932986B1 (fr) * 2008-06-26 2010-12-10 Michele Evrard Composition regeneratrice de la peau
FR2943253B1 (fr) 2009-03-20 2011-04-22 Oreal Composition contenant l'association de madecassoside, d'une arginine et de polysorbate
DE102009026718A1 (de) 2009-06-04 2010-04-15 Henkel Ag & Co. Kgaa Hautbehandlung zur Porenverfeinerung II
JP2011057634A (ja) * 2009-09-11 2011-03-24 Rohto Pharmaceutical Co Ltd 美白用組成物
WO2011043735A1 (en) * 2009-10-07 2011-04-14 Asian Phytoceuticals Public Company Limited A composition for modulating immune responses
US8685472B2 (en) 2010-03-01 2014-04-01 Access Business Group International Llc Skin whitening composition containing chia seed extract
CA2802154C (en) * 2010-06-10 2017-02-28 Indus Biotech Private Limited A method for preparation of highly pure asiaticoside composition from centella asiatica and a method of use thereof
WO2012050763A2 (en) 2010-09-29 2012-04-19 Access Business Group International Llc Chia seed extract and related method of manufacture
CN102603854A (zh) * 2011-01-25 2012-07-25 苏州宝泽堂医药科技有限公司 一种从积雪草中提取积雪草皂苷的方法
KR101245563B1 (ko) * 2011-03-16 2013-03-21 바이오스펙트럼 주식회사 마데카소사이드를 함유하는 피부 미백제
JP5926506B2 (ja) * 2011-06-23 2016-05-25 バイオランド・リミテッド コラーゲン産生促進剤の製造方法、ｍｍｐ−１阻害剤の製造方法及び皮膚外用組成物の製造方法
DE102011083293A1 (de) 2011-09-23 2013-03-28 Henkel Ag & Co. Kgaa Wasserfreie Formulierungen mit kühlender Wirkung
WO2014003224A1 (en) * 2012-06-29 2014-01-03 Bio Spectrum, Inc. Compositions for whitening skin comprising madecassoside
US12440530B2 (en) 2013-03-01 2025-10-14 Envy Medical, Inc. Skin solution with solubilized bakuchiol
FR3005575B1 (fr) * 2013-05-20 2016-01-01 Oreal Composition cosmetique comprenant un agent antipelliculaire, un bisabolol et un compose de type madecassoside, et procede de traitement cosmetique
WO2020112590A1 (en) 2018-11-27 2020-06-04 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Solubilised centella asiatica extract
CN112957379B (zh) * 2021-02-20 2022-04-08 上海珈凯生物科技有限公司 一种积雪草提取物的提取方法
WO2023036404A1 (en) 2021-09-07 2023-03-16 Symrise Ag Taste balancing botanical compounds
KR102725267B1 (ko) * 2021-10-19 2024-11-01 동국제약 주식회사 병풀 정량 추출물 및 마데카소사이드를 유효성분으로 함유하는 화장료 조성물
WO2023123046A1 (en) * 2021-12-29 2023-07-06 L'oreal Composition for caring for the skin
CN115228432B (zh) * 2022-05-31 2023-04-25 西南科技大学 用于放射性核素富集的生物质衍生碳包裹纳米零价铁材料的制备及应用
CN114989239B (zh) * 2022-07-05 2023-04-18 广西昌洲天然药业有限公司 一种从积雪草中分离羟基积雪草苷方法及计算机存储介质
KR102786604B1 (ko) * 2022-12-12 2025-03-26 주식회사 코스모바이오 병풀로부터 아시아티코사이드 및 마데카소사이드의 분리 정제 방법
KR20240129658A (ko) 2023-02-20 2024-08-28 국립한국교통대학교산학협력단 병풀 착즙물을 포함하는 항염증 조성물
KR102883448B1 (ko) * 2023-05-16 2025-11-06 대봉엘에스 주식회사 병풀 추출물을 포함하는 화장료 조성물
CN117530893A (zh) * 2023-12-23 2024-02-09 上海琦成化妆品有限公司 一种抗炎修复组合物及其应用
CN117898962A (zh) * 2024-01-23 2024-04-19 江南大学 一种具有皮肤修复功效的羟基积雪草苷组合物及其应用
KR20250117531A (ko) 2024-01-26 2025-08-05 국립한국교통대학교산학협력단 병풀 유래의 항염증 조성물
FR3162624A1 (fr) 2024-05-31 2025-12-05 L'oreal Composition comprenant au moins un actif antipelliculaire, au moins un agent antioxydant et au moins 35% en poids d’un monoalcool en C1 à C6
CN121489992A (zh) * 2026-01-12 2026-02-10 上海华之沃生物医药科技有限公司 积雪草提取物的制备工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5975M (https=) * 1966-08-08 1968-04-22
KR910002518B1 (ko) * 1989-03-09 1991-04-23 동국제약 주식회사 적설초에서 게닌성분 및 아시아티코사이드의 분리방법
KR100357848B1 (ko) 1996-04-23 2002-12-18 더 프록터 앤드 갬블 캄파니 비타민비3화합물을포함하는피부외관을조절하기위한국소용조성물
KR100228873B1 (ko) * 1997-03-24 1999-11-01 강재헌 센텔라아시아티카에서 분리한 아시아티코사이드와 마테카소 사이드의 수용성 추출물을 함유한 간세포 및 항간섬유화 치료제
FR2768927B1 (fr) * 1997-10-01 2000-01-21 Lvmh Rech Utilisation de l'acide ellagique, de ses sels, de ses complexes metalliques, de ses derives mono- ou poly-ethers, mono- ou poly-acyles dans le domaine de la cosmetique et de la pharmacie, notamment de la dermatologie
WO2001019365A1 (en) * 1999-09-15 2001-03-22 Roche Consumer Health Ag Pharmaceutical and/or cosmetical compositions
US6416769B1 (en) * 2000-03-03 2002-07-09 Australian Importers, Ltd. Cosmetic compositions comprising exfoliating enzymes and uses thereof

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101323637B (zh) * 2008-07-29 2010-12-22 卢照凯 一种积雪草甙及其制备方法
CN101407536B (zh) * 2008-11-27 2011-05-18 浙江大学 一种溶剂结晶法制备高纯度积雪草苷的工艺
CN103124560A (zh) * 2010-09-09 2013-05-29 纳图瑞克斯有限公司 制备积雪草提取物的方法
CN103124560B (zh) * 2010-09-09 2015-09-23 纳图瑞克斯有限公司 制备积雪草提取物的方法
CN102367263A (zh) * 2011-11-11 2012-03-07 上海师范大学 一种分离纯化积雪草三萜酸单葡萄糖苷的方法
CN102367263B (zh) * 2011-11-11 2013-05-29 上海师范大学 一种分离纯化积雪草三萜酸单葡萄糖苷的方法
CN105168051A (zh) * 2015-09-16 2015-12-23 任海锋 肤色遮盖液
CN105267056A (zh) * 2015-12-01 2016-01-27 江苏隆力奇生物科技股份有限公司 一种具有抗皱祛皱功能的护肤化妆品组合物及其应用
CN107412235A (zh) * 2017-06-28 2017-12-01 上海交通大学 一种积雪草中促进pc12细胞分化的单体组合及其应用
CN107903296A (zh) * 2017-11-29 2018-04-13 陶坤秀 羟基积雪草苷的提取方法
CN107903296B (zh) * 2017-11-29 2021-01-26 桂林融通科技有限公司 羟基积雪草苷的提取方法
CN112773806A (zh) * 2019-11-06 2021-05-11 鲁南制药集团股份有限公司 包含淫羊藿苷元和羟基积雪草酸的药物组合物的医药用途
CN112773806B (zh) * 2019-11-06 2024-03-19 鲁南制药集团股份有限公司 包含淫羊藿苷元和羟基积雪草酸的药物组合物的医药用途
CN111285916A (zh) * 2020-02-14 2020-06-16 浏阳朗林生物科技有限公司 一种积雪草总苷含量高的积雪草提取物的制备方法
CN111285916B (zh) * 2020-02-14 2021-07-02 浏阳朗林生物科技有限公司 一种积雪草总苷含量高的积雪草提取物的制备方法
CN116583260A (zh) * 2020-12-17 2023-08-11 欧莱雅 包含氨基酸和两种特定酸的两相化妆品组合物
CN116407478A (zh) * 2023-05-11 2023-07-11 杭州以息互联网科技有限公司 一种温和的祛痘组合物及其应用

Also Published As

Publication number Publication date
DE60328912D1 (de) 2009-10-01
AU2003296799A1 (en) 2004-08-10
CA2509421C (fr) 2012-02-07
JP4643275B2 (ja) 2011-03-02
US20080118581A1 (en) 2008-05-22
KR101122786B1 (ko) 2012-04-12
FR2848117B1 (fr) 2006-08-04
EP1569672A1 (fr) 2005-09-07
JP2006516962A (ja) 2006-07-13
US8486900B2 (en) 2013-07-16
EP1569672B1 (fr) 2009-08-19
US20120178706A1 (en) 2012-07-12
KR20110132629A (ko) 2011-12-08
ATE439852T1 (de) 2009-09-15
CA2509421A1 (fr) 2004-07-29
WO2004062678A1 (fr) 2004-07-29
US8163706B2 (en) 2012-04-24
KR20060069349A (ko) 2006-06-21
US20060106206A1 (en) 2006-05-18
ES2329568T3 (es) 2009-11-27
US7402669B2 (en) 2008-07-22
FR2848117A1 (fr) 2004-06-11

Similar Documents

Publication Publication Date Title
CN1774257A (zh) 制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法
CN1301543A (zh) 皮肤外用剂
CN1244317C (zh) 用于提高透明质酸产率的组合物及其制备方法
CN1187060C (zh) 鲨鱼软骨提取物及其制备方法和用途
CN1968707A (zh) 含d－甘露庚酮糖和/或甘露庚糖醇的组合物用于治疗和预防先天免疫变异疾病的用途
CN1826127A (zh) 用于促进热休克蛋白合成的一种含有以富含羽扇醇的提取物为活性成分的化妆品或药学组合物的用途
CN1229094C (zh) 美白用皮肤外用剂
CN1545402A (zh) 可增强表皮细胞中层粘蛋白5的产生的物质及其用途
CN1913863A (zh) 生物相容的盖仑基质的新配制方法
CN1630528A (zh) 含药用人参的脑细胞或神经细胞保护剂
CN1870972A (zh) 包含骆驼奶或其成分的化妆品组合物
CN1687099A (zh) 射干总黄酮提取物及其制备方法和其在药物制备中的应用
CN1901926A (zh) 含有葫芦科植物提取物或者从其中分离的具有抗脂肪形成和抗肥胖症活性的纯化提取物的组合物
CN1713889A (zh) 皮肤外用剂组成物及其使用方法
CN1652743A (zh) 毛发生长补剂
CN1559519A (zh) 一种夏枯草提取物及其制备方法与用途
CN1784215A (zh) 促黑色素生成剂及促黑色素生成组合物
CN1535711A (zh) 治疗烧烫伤、皮肤粘膜溃疡的药物组合物
CN1226818A (zh) 头部用组合物
CN1652805A (zh) 一种用于治疗和改善支气管呼吸困难的草药组合物
CN1927312A (zh) 一种含有葡萄提取物的药物组合物及其制备方法、用途
CN1100062C (zh) 一种治疗早老性痴呆和及脑卒中后遗症的新药
CN1175877C (zh) 一枝黄花注射用脂肪乳剂及制备方法
CN1668561A (zh) 治疗药
CN1152044C (zh) 从白首乌中提取分离具有抗肿瘤作用的新颖碳-21甾体苷

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20060517