CN1290502C - 治疗普通感冒的组合物 - Google Patents

治疗普通感冒的组合物 Download PDF

Info

Publication number
CN1290502C
CN1290502C CNB028182871A CN02818287A CN1290502C CN 1290502 C CN1290502 C CN 1290502C CN B028182871 A CNB028182871 A CN B028182871A CN 02818287 A CN02818287 A CN 02818287A CN 1290502 C CN1290502 C CN 1290502C
Authority
CN
China
Prior art keywords
salt
xylometazoline
acid
compositions
atem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB028182871A
Other languages
English (en)
Chinese (zh)
Other versions
CN1555263A (zh
Inventor
汉尼·安内特·莫斯卡德
卡琳·洛温斯坦·可瑞思丁森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Denmark Nykomin Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denmark Nykomin Co ltd filed Critical Denmark Nykomin Co ltd
Publication of CN1555263A publication Critical patent/CN1555263A/zh
Application granted granted Critical
Publication of CN1290502C publication Critical patent/CN1290502C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Cosmetics (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CNB028182871A 2001-09-18 2002-09-18 治疗普通感冒的组合物 Expired - Lifetime CN1290502C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101356 2001-09-18
DKPA200101356 2001-09-18

Publications (2)

Publication Number Publication Date
CN1555263A CN1555263A (zh) 2004-12-15
CN1290502C true CN1290502C (zh) 2006-12-20

Family

ID=8160714

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028182871A Expired - Lifetime CN1290502C (zh) 2001-09-18 2002-09-18 治疗普通感冒的组合物

Country Status (20)

Country Link
US (2) US7652030B2 (enExample)
EP (2) EP1661570A3 (enExample)
JP (1) JP4500045B2 (enExample)
KR (1) KR100810872B1 (enExample)
CN (1) CN1290502C (enExample)
AT (1) ATE318601T1 (enExample)
BR (1) BRPI0212586B8 (enExample)
CA (1) CA2460140C (enExample)
DE (1) DE60209511T2 (enExample)
DK (1) DK1446119T3 (enExample)
EA (1) EA008165B1 (enExample)
ES (1) ES2259098T3 (enExample)
HU (1) HU226527B1 (enExample)
MX (1) MXPA04002500A (enExample)
NO (1) NO334441B1 (enExample)
NZ (1) NZ531792A (enExample)
PL (1) PL208686B1 (enExample)
PT (1) PT1446119E (enExample)
SI (1) SI1446119T1 (enExample)
WO (1) WO2003024433A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DE60209511T2 (de) * 2001-09-18 2006-10-05 Nycomed Danmark Aps Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
AU2005210086A1 (en) * 2004-02-06 2005-08-18 Meda Pharma Gmbh & Co. Kg Treatment of rhinitis with anticholinergics alone in combination with antihistamines phosphodiesterase 4 inhibitors, or corticosteroids
WO2005084330A2 (en) * 2004-03-02 2005-09-15 Synergia Pharma, Inc. Compositions and methods for treating nasal congestion
DE102004049008A1 (de) * 2004-10-05 2006-04-06 Merck Patent Gmbh Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur
CA2592605C (en) * 2004-12-27 2010-12-07 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
DE102006023770A1 (de) * 2006-05-20 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Treibgasfreie Aerosolformulierung für die Inhalation
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US20090270472A1 (en) * 2008-04-25 2009-10-29 Kenneth Gould Method to use oxymetazoline to interrupt the development of the common cold syndrome
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
MX2012005961A (es) 2009-11-25 2012-06-14 Boehringer Ingelheim Int Nebulizador.
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2978407B1 (en) * 2013-03-29 2020-05-06 Santa Farma Ilaç Sanayi A.S. Aqueous solution composition containing ipratropium and oxymetazoline
WO2014158118A1 (en) * 2013-03-29 2014-10-02 Santa Farma İlaç Sanayi̇ A.Ş. Suspension composition containing ipratropium and oxymetazoline
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
WO2015054359A1 (en) * 2013-10-08 2015-04-16 Ebadi Mark A Methods and compositions for symptomatic reflief of the common cold
HUE058904T2 (hu) 2014-05-07 2022-09-28 Boehringer Ingelheim Int Porlasztókészülék
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
CA2948071C (en) 2014-05-07 2022-08-30 Boehringer Ingelheim International Gmbh Container, nebulizer and use
EP3236933B1 (en) 2014-12-24 2018-11-14 JADRAN - GALENSKI LABORATORIJ d.d. A nasal composition containing sea water as stability-improving excipient
MX383771B (es) 2015-12-02 2025-03-14 Pablo Cortes Borrego Combinación de oximetazolina e ipratropio en aplicación tópica nasal para el tratamiento de la tos.
US20220031739A1 (en) * 2020-07-31 2022-02-03 Eye Therapies Llc Anti-viral compositions and methods of use thereof
CN121868276A (zh) * 2022-10-25 2026-04-17 广东药科大学 托品酸及其衍生物在制备免疫与炎症相关疾病治疗药物中的医药用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2137981T3 (es) * 1991-11-19 2000-01-01 Univ Virginia Tratamiento combinado por agentes antimediaticos y antiviricos de resfriados comunes.
IL101056A (en) 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
GB9218834D0 (en) 1992-09-05 1992-10-21 Procter & Gamble Nasal spray products
ES2129117T3 (es) * 1992-12-09 1999-06-01 Boehringer Ingelheim Pharma Formulaciones en disolucion en forma de aerosol medicinales estabilizadas.
EP0780127A1 (en) 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
IL131492A0 (en) * 1997-04-30 2001-01-28 Warner Lambert Co Topical nasal antiinflammatory compositions
WO1999038492A1 (en) * 1998-01-30 1999-08-05 Novartis Consumer Health S.A. Nasal solutions
ATE253896T1 (de) 1998-06-18 2003-11-15 Boehringer Ingelheim Pharma Zwei oder mehrere wirkstoffe enthaltende pharmazeutische aerosolformulierungen
CZ295595B6 (cs) * 1999-06-22 2005-08-17 Boehringer Ingelheim International Gmbh Stálý roztok xylometazolinu a oxymetazolinu
DE60209511T2 (de) * 2001-09-18 2006-10-05 Nycomed Danmark Aps Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten

Also Published As

Publication number Publication date
NZ531792A (en) 2006-02-24
HU226527B1 (hu) 2009-03-30
EP1446119B1 (en) 2006-03-01
CN1555263A (zh) 2004-12-15
ATE318601T1 (de) 2006-03-15
EA200400444A1 (ru) 2005-02-24
HUP0402075A2 (hu) 2005-02-28
US8450339B2 (en) 2013-05-28
ES2259098T3 (es) 2006-09-16
DE60209511D1 (de) 2006-04-27
KR100810872B1 (ko) 2008-03-06
PL370536A1 (en) 2005-05-30
JP2005505569A (ja) 2005-02-24
US20100093783A1 (en) 2010-04-15
WO2003024433A2 (en) 2003-03-27
EP1661570A2 (en) 2006-05-31
EA008165B1 (ru) 2007-04-27
HUP0402075A3 (en) 2008-04-28
US20040248924A1 (en) 2004-12-09
WO2003024433A3 (en) 2004-06-10
BRPI0212586B8 (pt) 2021-05-25
DK1446119T3 (da) 2006-07-10
KR20040049849A (ko) 2004-06-12
EP1661570A3 (en) 2012-10-24
DE60209511T2 (de) 2006-10-05
US7652030B2 (en) 2010-01-26
NO20041070L (no) 2004-05-18
HK1067984A1 (en) 2005-04-22
EP1446119A2 (en) 2004-08-18
PT1446119E (pt) 2006-07-31
PL208686B1 (pl) 2011-05-31
CA2460140A1 (en) 2003-03-27
CA2460140C (en) 2009-09-01
BR0212586B1 (pt) 2013-11-19
NO334441B1 (no) 2014-03-03
BR0212586A (pt) 2004-10-13
MXPA04002500A (es) 2004-11-22
JP4500045B2 (ja) 2010-07-14
SI1446119T1 (sl) 2006-08-31

Similar Documents

Publication Publication Date Title
CN1555263A (zh) 治疗普通感冒的组合物
JP5683719B2 (ja) ベポタスチン組成物
CN100346788C (zh) 用于鼻内给药的芬太尼组合物
CN1607950A (zh) 用于口腔施用的包含烟碱的液体药物制剂
CN1050514C (zh) 眼用或鼻用抗过敏组合物
CN1717227A (zh) 含类黄酮和薄荷醇的药物组合物
US11691950B2 (en) Isoquinoline-steroid conjugates and uses thereof
CN1302605A (zh) 缓释的口服给药组合物
CN1551768A (zh) 新型取代的苯并咪唑剂型及其应用方法
CN1802157A (zh) 用于肺吸入的包含阿扑吗啡的药物组合物
EP2624836B1 (en) Bepotastine compositions
CN1842334A (zh) 化合物在睡眠障碍治疗中的用途
CN101031283A (zh) 用于递药的药用组合物和用其治疗或预防病症的方法
CN1527706A (zh) 含特比萘芬的药物组合物及其应用
CN1738612A (zh) 含酮洛芬的饮用制剂以及其在导致一群动物发烧、炎症和疼痛状况的同时治疗中的应用
CN1537004A (zh) 用于经鼻给药的含有咪唑并三嗪酮化合物的组合物
CN1617723A (zh) 化合物在睡眠障碍等的治疗、在醒时使精力恢复方面的用途以及治疗与之相伴的头晕眼花的方法
JP2008512429A (ja) ロフルミラストとｓｙｋインヒビターとの組合せ物並びにその使用方法
CN1184962C (zh) 口服舍曲林浓缩物
CN1942193A (zh) 用于紧急糖皮质激素治疗的药物组合物
US9730889B2 (en) Steroid-sparing effects of beta-adrenergic inverse agonists and uses thereof
US20230128304A1 (en) Benzimidazole compound for the treatment of metabolic disorders
CN1929822A (zh) 用于递送催眠药穿过口腔粘膜的组合物及其用法
CN1876004A (zh) 一种治疗脑血管病的药物
CN100345594C (zh) 乙酰唑胺滴眼液

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: NYCOMED DENMARK CO., LTD.

Free format text: FORMER NAME: NYCOMED DANMARK AS

CP01 Change in the name or title of a patent holder

Address after: DanMai Los Gerd

Patentee after: NYCOMED DANMARK APS

Address before: DanMai Los Gerd

Patentee before: Denmark Nykomin Co.,Ltd.

C56 Change in the name or address of the patentee

Owner name: TAKEDA PHARMACEUTICALS LTD.

Free format text: FORMER NAME: NYCOMED DANMARK AS

CP01 Change in the name or title of a patent holder

Address after: DanMai Los Gerd

Patentee after: Takeda pharmaceutical Limited by Share Ltd.

Address before: DanMai Los Gerd

Patentee before: Nycomed Danmark APS

C56 Change in the name or address of the patentee
CP02 Change in the address of a patent holder

Address after: Tasmania, Denmark

Patentee after: Takeda pharmaceutical Limited by Share Ltd.

Address before: DanMai Los Gerd

Patentee before: Takeda pharmaceutical Limited by Share Ltd.

CX01 Expiry of patent term

Granted publication date: 20061220

CX01 Expiry of patent term