DE60209511T2 - Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten - Google Patents

Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten Download PDF

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Publication number
DE60209511T2
DE60209511T2 DE60209511T DE60209511T DE60209511T2 DE 60209511 T2 DE60209511 T2 DE 60209511T2 DE 60209511 T DE60209511 T DE 60209511T DE 60209511 T DE60209511 T DE 60209511T DE 60209511 T2 DE60209511 T2 DE 60209511T2
Authority
DE
Germany
Prior art keywords
xylometazoline
salt
ipratropium
composition
nasal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60209511T
Other languages
German (de)
English (en)
Other versions
DE60209511D1 (de
Inventor
Anette Hanne MOESGAARD
Lowenstein Karin CHRISTENSEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharma AS
Original Assignee
Nycomed Danmark AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Danmark AS filed Critical Nycomed Danmark AS
Application granted granted Critical
Publication of DE60209511D1 publication Critical patent/DE60209511D1/de
Publication of DE60209511T2 publication Critical patent/DE60209511T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
DE60209511T 2001-09-18 2002-09-18 Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten Expired - Lifetime DE60209511T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101356 2001-09-18
DK200101356 2001-09-18
PCT/IB2002/003828 WO2003024433A2 (en) 2001-09-18 2002-09-18 Compositions for treatment of common cold, comprising ipratropium and xylometazoline

Publications (2)

Publication Number Publication Date
DE60209511D1 DE60209511D1 (de) 2006-04-27
DE60209511T2 true DE60209511T2 (de) 2006-10-05

Family

ID=8160714

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60209511T Expired - Lifetime DE60209511T2 (de) 2001-09-18 2002-09-18 Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten

Country Status (20)

Country Link
US (2) US7652030B2 (enExample)
EP (2) EP1446119B1 (enExample)
JP (1) JP4500045B2 (enExample)
KR (1) KR100810872B1 (enExample)
CN (1) CN1290502C (enExample)
AT (1) ATE318601T1 (enExample)
BR (1) BRPI0212586B8 (enExample)
CA (1) CA2460140C (enExample)
DE (1) DE60209511T2 (enExample)
DK (1) DK1446119T3 (enExample)
EA (1) EA008165B1 (enExample)
ES (1) ES2259098T3 (enExample)
HU (1) HU226527B1 (enExample)
MX (1) MXPA04002500A (enExample)
NO (1) NO334441B1 (enExample)
NZ (1) NZ531792A (enExample)
PL (1) PL208686B1 (enExample)
PT (1) PT1446119E (enExample)
SI (1) SI1446119T1 (enExample)
WO (1) WO2003024433A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DK1446119T3 (da) * 2001-09-18 2006-07-10 Nycomed Danmark Aps Præparater omfattende Ipratropium og xylometazolin til behandling af almindelig forkölelse
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
WO2005074983A2 (en) * 2004-02-06 2005-08-18 Meda Pharma Gmbh & Co. Kg Treatment of rhinitis with anticholinergics alone in combination with antihistamines phosphodiesterase 4 inhibitors, or corticosteroids
WO2005084330A2 (en) * 2004-03-02 2005-09-15 Synergia Pharma, Inc. Compositions and methods for treating nasal congestion
DE102004049008A1 (de) 2004-10-05 2006-04-06 Merck Patent Gmbh Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur
NZ555693A (en) * 2004-12-27 2010-10-29 Eisai R&D Man Co Ltd Matrix type sustained-release preparation containing donepezil
DE102006023770A1 (de) * 2006-05-20 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Treibgasfreie Aerosolformulierung für die Inhalation
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US20090270472A1 (en) * 2008-04-25 2009-10-29 Kenneth Gould Method to use oxymetazoline to interrupt the development of the common cold syndrome
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EA026241B1 (ru) 2009-11-25 2017-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2978407B1 (en) * 2013-03-29 2020-05-06 Santa Farma Ilaç Sanayi A.S. Aqueous solution composition containing ipratropium and oxymetazoline
WO2014158118A1 (en) * 2013-03-29 2014-10-02 Santa Farma İlaç Sanayi̇ A.Ş. Suspension composition containing ipratropium and oxymetazoline
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
WO2015054359A1 (en) * 2013-10-08 2015-04-16 Ebadi Mark A Methods and compositions for symptomatic reflief of the common cold
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
AU2015258107B2 (en) 2014-05-07 2019-12-19 Boehringer Ingelheim International Gmbh Nebulizer
WO2015169732A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Container, nebulizer and use
PL3236933T3 (pl) * 2014-12-24 2019-05-31 Jadran Galenski Laboratorij D D Kompozycja do podawania donosowego zawierająca wodę morską jako zaróbkę poprawiającą trwałość
MX383771B (es) * 2015-12-02 2025-03-14 Pablo Cortes Borrego Combinación de oximetazolina e ipratropio en aplicación tópica nasal para el tratamiento de la tos.
US20220031739A1 (en) * 2020-07-31 2022-02-03 Eye Therapies Llc Anti-viral compositions and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2122719A1 (en) * 1991-11-19 1993-05-27 Jack M. Gwaltney, Jr. Combined virustatic antimediator (covam) treatment of common colds
IL101056A (en) * 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
GB9218834D0 (en) 1992-09-05 1992-10-21 Procter & Gamble Nasal spray products
EP0673240B1 (en) 1992-12-09 1999-03-24 Boehringer Ingelheim Pharmaceuticals Inc. Stabilized medicinal aerosol solution formulations
EP0780127A1 (en) 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
BR9809022A (pt) 1997-04-30 2000-08-01 Warner Lambert Co Composições antiinflamatórias nasais tópicas
NZ505919A (en) * 1998-01-30 2002-10-25 Novartis Consumer Health S Nasal solutions
EP1087750B1 (en) 1998-06-18 2003-11-12 Boehringer Ingelheim Pharmaceuticals Inc. Pharmaceutical formulations for aerosols with two or more active substances
AU765736B2 (en) * 1999-06-22 2003-09-25 Boehringer Ingelheim International Gmbh Stable xylometazoline and oxymetazoline solution
DK1446119T3 (da) * 2001-09-18 2006-07-10 Nycomed Danmark Aps Præparater omfattende Ipratropium og xylometazolin til behandling af almindelig forkölelse

Also Published As

Publication number Publication date
SI1446119T1 (sl) 2006-08-31
EP1446119B1 (en) 2006-03-01
BR0212586A (pt) 2004-10-13
US8450339B2 (en) 2013-05-28
EA200400444A1 (ru) 2005-02-24
HK1067984A1 (en) 2005-04-22
KR20040049849A (ko) 2004-06-12
BR0212586B1 (pt) 2013-11-19
US20100093783A1 (en) 2010-04-15
WO2003024433A2 (en) 2003-03-27
EP1661570A3 (en) 2012-10-24
EP1661570A2 (en) 2006-05-31
JP2005505569A (ja) 2005-02-24
NO334441B1 (no) 2014-03-03
ES2259098T3 (es) 2006-09-16
HUP0402075A3 (en) 2008-04-28
DE60209511D1 (de) 2006-04-27
HU226527B1 (hu) 2009-03-30
NO20041070L (no) 2004-05-18
CN1555263A (zh) 2004-12-15
NZ531792A (en) 2006-02-24
WO2003024433A3 (en) 2004-06-10
US20040248924A1 (en) 2004-12-09
CA2460140C (en) 2009-09-01
HUP0402075A2 (hu) 2005-02-28
PT1446119E (pt) 2006-07-31
EA008165B1 (ru) 2007-04-27
PL208686B1 (pl) 2011-05-31
US7652030B2 (en) 2010-01-26
CA2460140A1 (en) 2003-03-27
CN1290502C (zh) 2006-12-20
EP1446119A2 (en) 2004-08-18
DK1446119T3 (da) 2006-07-10
JP4500045B2 (ja) 2010-07-14
ATE318601T1 (de) 2006-03-15
BRPI0212586B8 (pt) 2021-05-25
PL370536A1 (en) 2005-05-30
KR100810872B1 (ko) 2008-03-06
MXPA04002500A (es) 2004-11-22

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