JP4500045B2 - 感冒の治療のための組成物 - Google Patents
感冒の治療のための組成物 Download PDFInfo
- Publication number
- JP4500045B2 JP4500045B2 JP2003528530A JP2003528530A JP4500045B2 JP 4500045 B2 JP4500045 B2 JP 4500045B2 JP 2003528530 A JP2003528530 A JP 2003528530A JP 2003528530 A JP2003528530 A JP 2003528530A JP 4500045 B2 JP4500045 B2 JP 4500045B2
- Authority
- JP
- Japan
- Prior art keywords
- salt
- acid
- xylometazoline
- ipratropium
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 229960001095 xylometazoline hydrochloride Drugs 0.000 claims abstract description 60
- YGWFCQYETHJKNX-UHFFFAOYSA-N 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1h-imidazol-3-ium;chloride Chemical compound [Cl-].CC1=CC(C(C)(C)C)=CC(C)=C1CC1=NCC[NH2+]1 YGWFCQYETHJKNX-UHFFFAOYSA-N 0.000 claims abstract description 59
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- 235000002639 sodium chloride Nutrition 0.000 claims description 137
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- Pulmonology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Polyurethanes Or Polyureas (AREA)
- Cosmetics (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101356 | 2001-09-18 | ||
| PCT/IB2002/003828 WO2003024433A2 (en) | 2001-09-18 | 2002-09-18 | Compositions for treatment of common cold, comprising ipratropium and xylometazoline |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005505569A JP2005505569A (ja) | 2005-02-24 |
| JP2005505569A5 JP2005505569A5 (enExample) | 2005-12-15 |
| JP4500045B2 true JP4500045B2 (ja) | 2010-07-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003528530A Expired - Lifetime JP4500045B2 (ja) | 2001-09-18 | 2002-09-18 | 感冒の治療のための組成物 |
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|---|---|
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| EP (2) | EP1661570A3 (enExample) |
| JP (1) | JP4500045B2 (enExample) |
| KR (1) | KR100810872B1 (enExample) |
| CN (1) | CN1290502C (enExample) |
| AT (1) | ATE318601T1 (enExample) |
| BR (1) | BRPI0212586B8 (enExample) |
| CA (1) | CA2460140C (enExample) |
| DE (1) | DE60209511T2 (enExample) |
| DK (1) | DK1446119T3 (enExample) |
| EA (1) | EA008165B1 (enExample) |
| ES (1) | ES2259098T3 (enExample) |
| HU (1) | HU226527B1 (enExample) |
| MX (1) | MXPA04002500A (enExample) |
| NO (1) | NO334441B1 (enExample) |
| NZ (1) | NZ531792A (enExample) |
| PL (1) | PL208686B1 (enExample) |
| PT (1) | PT1446119E (enExample) |
| SI (1) | SI1446119T1 (enExample) |
| WO (1) | WO2003024433A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| DE60209511T2 (de) * | 2001-09-18 | 2006-10-05 | Nycomed Danmark Aps | Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten |
| TWI359675B (en) * | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| AU2005210086A1 (en) * | 2004-02-06 | 2005-08-18 | Meda Pharma Gmbh & Co. Kg | Treatment of rhinitis with anticholinergics alone in combination with antihistamines phosphodiesterase 4 inhibitors, or corticosteroids |
| WO2005084330A2 (en) * | 2004-03-02 | 2005-09-15 | Synergia Pharma, Inc. | Compositions and methods for treating nasal congestion |
| DE102004049008A1 (de) * | 2004-10-05 | 2006-04-06 | Merck Patent Gmbh | Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur |
| CA2592605C (en) * | 2004-12-27 | 2010-12-07 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| DE102006023770A1 (de) * | 2006-05-20 | 2007-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Treibgasfreie Aerosolformulierung für die Inhalation |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| US20090270472A1 (en) * | 2008-04-25 | 2009-10-29 | Kenneth Gould | Method to use oxymetazoline to interrupt the development of the common cold syndrome |
| EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
| EP2432531B1 (de) | 2009-05-18 | 2019-03-06 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
| MX2012005961A (es) | 2009-11-25 | 2012-06-14 | Boehringer Ingelheim Int | Nebulizador. |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2011064163A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2585151B1 (en) | 2010-06-24 | 2018-04-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| WO2012130757A1 (de) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| EP2978407B1 (en) * | 2013-03-29 | 2020-05-06 | Santa Farma Ilaç Sanayi A.S. | Aqueous solution composition containing ipratropium and oxymetazoline |
| WO2014158118A1 (en) * | 2013-03-29 | 2014-10-02 | Santa Farma İlaç Sanayi̇ A.Ş. | Suspension composition containing ipratropium and oxymetazoline |
| JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| EP2835146B1 (en) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Nebulizer |
| WO2015054359A1 (en) * | 2013-10-08 | 2015-04-16 | Ebadi Mark A | Methods and compositions for symptomatic reflief of the common cold |
| HUE058904T2 (hu) | 2014-05-07 | 2022-09-28 | Boehringer Ingelheim Int | Porlasztókészülék |
| US10722666B2 (en) | 2014-05-07 | 2020-07-28 | Boehringer Ingelheim International Gmbh | Nebulizer with axially movable and lockable container and indicator |
| CA2948071C (en) | 2014-05-07 | 2022-08-30 | Boehringer Ingelheim International Gmbh | Container, nebulizer and use |
| EP3236933B1 (en) | 2014-12-24 | 2018-11-14 | JADRAN - GALENSKI LABORATORIJ d.d. | A nasal composition containing sea water as stability-improving excipient |
| MX383771B (es) | 2015-12-02 | 2025-03-14 | Pablo Cortes Borrego | Combinación de oximetazolina e ipratropio en aplicación tópica nasal para el tratamiento de la tos. |
| US20220031739A1 (en) * | 2020-07-31 | 2022-02-03 | Eye Therapies Llc | Anti-viral compositions and methods of use thereof |
| CN121868276A (zh) * | 2022-10-25 | 2026-04-17 | 广东药科大学 | 托品酸及其衍生物在制备免疫与炎症相关疾病治疗药物中的医药用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2137981T3 (es) * | 1991-11-19 | 2000-01-01 | Univ Virginia | Tratamiento combinado por agentes antimediaticos y antiviricos de resfriados comunes. |
| IL101056A (en) | 1992-02-24 | 1997-03-18 | Res & Dev Co Ltd | Composition for nasal treatment |
| GB9218834D0 (en) | 1992-09-05 | 1992-10-21 | Procter & Gamble | Nasal spray products |
| ES2129117T3 (es) * | 1992-12-09 | 1999-06-01 | Boehringer Ingelheim Pharma | Formulaciones en disolucion en forma de aerosol medicinales estabilizadas. |
| EP0780127A1 (en) | 1995-12-19 | 1997-06-25 | The Procter & Gamble Company | A nasal spray containing a steroid and a antihistamine |
| DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
| IL131492A0 (en) * | 1997-04-30 | 2001-01-28 | Warner Lambert Co | Topical nasal antiinflammatory compositions |
| WO1999038492A1 (en) * | 1998-01-30 | 1999-08-05 | Novartis Consumer Health S.A. | Nasal solutions |
| ATE253896T1 (de) | 1998-06-18 | 2003-11-15 | Boehringer Ingelheim Pharma | Zwei oder mehrere wirkstoffe enthaltende pharmazeutische aerosolformulierungen |
| CZ295595B6 (cs) * | 1999-06-22 | 2005-08-17 | Boehringer Ingelheim International Gmbh | Stálý roztok xylometazolinu a oxymetazolinu |
| DE60209511T2 (de) * | 2001-09-18 | 2006-10-05 | Nycomed Danmark Aps | Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten |
-
2002
- 2002-09-18 DE DE60209511T patent/DE60209511T2/de not_active Expired - Lifetime
- 2002-09-18 WO PCT/IB2002/003828 patent/WO2003024433A2/en not_active Ceased
- 2002-09-18 DK DK02765268T patent/DK1446119T3/da active
- 2002-09-18 JP JP2003528530A patent/JP4500045B2/ja not_active Expired - Lifetime
- 2002-09-18 US US10/489,655 patent/US7652030B2/en not_active Expired - Lifetime
- 2002-09-18 ES ES02765268T patent/ES2259098T3/es not_active Expired - Lifetime
- 2002-09-18 CA CA002460140A patent/CA2460140C/en not_active Expired - Lifetime
- 2002-09-18 NZ NZ531792A patent/NZ531792A/en not_active IP Right Cessation
- 2002-09-18 CN CNB028182871A patent/CN1290502C/zh not_active Expired - Lifetime
- 2002-09-18 PL PL370536A patent/PL208686B1/pl unknown
- 2002-09-18 BR BRPI0212586A patent/BRPI0212586B8/pt not_active IP Right Cessation
- 2002-09-18 KR KR1020047003882A patent/KR100810872B1/ko not_active Expired - Lifetime
- 2002-09-18 PT PT02765268T patent/PT1446119E/pt unknown
- 2002-09-18 EP EP06075452A patent/EP1661570A3/en not_active Withdrawn
- 2002-09-18 HU HU0402075A patent/HU226527B1/hu unknown
- 2002-09-18 EA EA200400444A patent/EA008165B1/ru unknown
- 2002-09-18 SI SI200230311T patent/SI1446119T1/sl unknown
- 2002-09-18 EP EP02765268A patent/EP1446119B1/en not_active Expired - Lifetime
- 2002-09-18 AT AT02765268T patent/ATE318601T1/de active
- 2002-09-18 MX MXPA04002500A patent/MXPA04002500A/es active IP Right Grant
-
2004
- 2004-03-12 NO NO20041070A patent/NO334441B1/no not_active IP Right Cessation
-
2009
- 2009-12-11 US US12/654,145 patent/US8450339B2/en not_active Expired - Fee Related
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