CN1268745C - B组链球菌抗原 - Google Patents

B组链球菌抗原 Download PDF

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Publication number
CN1268745C
CN1268745C CNB998052485A CN99805248A CN1268745C CN 1268745 C CN1268745 C CN 1268745C CN B998052485 A CNB998052485 A CN B998052485A CN 99805248 A CN99805248 A CN 99805248A CN 1268745 C CN1268745 C CN 1268745C
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CN
China
Prior art keywords
leu
lys
ile
ser
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB998052485A
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English (en)
Chinese (zh)
Other versions
CN1297482A (zh
Inventor
B·R·布罗多伊尔
C·里奥克斯
M·波耶尔
I·查勒波伊斯
J·哈梅尔
D·马丁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shire Canada Inc
ID Biomedical Corp of Quebec
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Biochem Pharma Inc
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Publication of CN1297482A publication Critical patent/CN1297482A/zh
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Publication of CN1268745C publication Critical patent/CN1268745C/zh
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB998052485A 1998-02-20 1999-02-17 B组链球菌抗原 Expired - Lifetime CN1268745C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7542598P 1998-02-20 1998-02-20
US60/075,425 1998-02-20
US60/075425 1998-02-20

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2006100913640A Division CN1944652A (zh) 1998-02-20 1999-02-17 B组链球菌抗原

Publications (2)

Publication Number Publication Date
CN1297482A CN1297482A (zh) 2001-05-30
CN1268745C true CN1268745C (zh) 2006-08-09

Family

ID=22125658

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB998052485A Expired - Lifetime CN1268745C (zh) 1998-02-20 1999-02-17 B组链球菌抗原
CNA2006100913640A Pending CN1944652A (zh) 1998-02-20 1999-02-17 B组链球菌抗原

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2006100913640A Pending CN1944652A (zh) 1998-02-20 1999-02-17 B组链球菌抗原

Country Status (22)

Country Link
US (4) US20030031682A1 (enExample)
EP (3) EP1757697A3 (enExample)
JP (2) JP4637350B2 (enExample)
KR (1) KR100771148B1 (enExample)
CN (2) CN1268745C (enExample)
AP (1) AP2000001886A0 (enExample)
AT (1) ATE347600T1 (enExample)
AU (1) AU2505999A (enExample)
CA (1) CA2321106C (enExample)
CZ (1) CZ301056B6 (enExample)
DE (1) DE69934299T2 (enExample)
EA (1) EA200000860A1 (enExample)
ES (2) ES2278436T3 (enExample)
HU (1) HU228497B1 (enExample)
ID (1) ID27482A (enExample)
IL (3) IL137921A0 (enExample)
NO (2) NO330491B1 (enExample)
NZ (1) NZ529854A (enExample)
OA (1) OA11686A (enExample)
TR (1) TR200002437T2 (enExample)
WO (1) WO1999042588A2 (enExample)
ZA (1) ZA991325B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2000001886A0 (en) * 1998-02-20 2000-09-30 Iaf Biochem Int Group B streptococcus antigens.
US7098182B2 (en) 1998-07-27 2006-08-29 Microbial Technics Limited Nucleic acids and proteins from group B streptococcus
WO2000006736A2 (en) * 1998-07-27 2000-02-10 Microbial Technics Limited Nucleic acids and proteins from group b streptococcus
CN101066447A (zh) 1998-12-22 2007-11-07 微科学有限公司 基因和蛋白质,及它们的用途
GB0105922D0 (en) * 2001-03-09 2001-04-25 Microscience Ltd Genes and proteins, and their use
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
CA2382795A1 (en) * 1999-08-25 2001-03-01 Medimmune, Inc. Homologs of a pneumococcal protein and fragments for vaccines
US6833356B1 (en) 1999-08-25 2004-12-21 Medimmune, Inc. Pneumococcal protein homologs and fragments for vaccines
US6833134B2 (en) 2000-06-12 2004-12-21 University Of Saskacthewan Immunization of dairy cattle with GapC protein against Streptococcus infection
US6866855B2 (en) 2000-06-12 2005-03-15 University Of Saskatchewan Immunization of dairy cattle with GapC protein against Streptococcus infection
DE60136356D1 (de) 2000-06-12 2008-12-11 Univ Saskatchewan Chimäres GapC Protein aus Streptococcus und dessen Verwendung zur Impfung und Diagnostik
ES2273861T3 (es) * 2000-06-12 2007-05-16 University Of Saskatchewan Inmunizacion de ganado vacuno lechero con proteina gapc frente a infecciones por streptococcus.
EP1734050A3 (en) * 2000-06-12 2012-12-05 University Of Saskatchewan Immunization of dairy cattle with GapC protein against streptococcus infection
US7335368B2 (en) 2000-10-13 2008-02-26 Id Biomedical Corporation BVH-A2 and BVH-A3 antigens of group B Streptococcus
ES2330083T3 (es) 2000-10-27 2009-12-04 Novartis Vaccines And Diagnostics S.R.L. Acidos nucleicos y proteinas de estreptococos de los grupos a y b.
JP4080876B2 (ja) * 2000-12-21 2008-04-23 アイディー バイオメディカル コーポレイション ストレプトコッカス・ピオゲネス抗原及び対応するｄｎａフラグメント
FR2824074A1 (fr) * 2001-04-26 2002-10-31 Pasteur Institut Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
ATE543906T1 (de) * 2002-02-11 2012-02-15 Id Biomedical Corp Antigen von streptococcus aus der b-gruppe
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
ES2505695T3 (es) 2003-07-31 2014-10-10 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunógenas para Streptococcus pyogenes
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
CA2575548A1 (en) 2004-07-29 2006-07-27 John L. Telford Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
EP1807446A2 (en) 2004-10-08 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Immunogenic and therapeutic compositions for streptococcus pyogenes
EP1845944A4 (en) * 2005-02-08 2011-07-27 Id Biomedical Corp Of Quebec C O B As Glaxosmithkline Biolog North America PHARMACEUTICAL COMPOSITIONS
GB0605247D0 (en) * 2006-03-15 2006-04-26 Chiron Srl Compositions and methods for immunisation
JP5653215B2 (ja) 2007-09-12 2015-01-14 ノバルティス アーゲー Ｇａｓ５７変異体抗原およびｇａｓ５７抗体
EP2537857B1 (en) 2007-12-21 2017-01-18 GlaxoSmithKline Biologicals SA Mutant forms of streptolysin O
CN102304185A (zh) * 2011-09-02 2012-01-04 黑龙江八一农垦大学 预防奶牛乳房炎的融合蛋白sip-trap及制备方法和应用
EP2949340A1 (en) * 2014-05-30 2015-12-02 IDT Biologika GmbH Vaccine composition against Streptococcus suis infection
CN115057944B (zh) * 2022-06-24 2025-06-24 南京农业大学 一种针对所有gbs血清型的多表位亚单位疫苗

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431739A (en) 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein
US4425437A (en) 1979-11-05 1984-01-10 Genentech, Inc. Microbial polypeptide expression vehicle
US5302386A (en) * 1986-04-16 1994-04-12 Brigham And Women's Hospital, Inc. Bacterial antigens, antibodies, vaccines and methods of manufacture
US5472696A (en) * 1988-02-26 1995-12-05 Univ. Of Florida Research Foundation, Inc. Antigen of group B streptococci
US5648241A (en) * 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
US5679768A (en) * 1991-02-15 1997-10-21 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US5225331A (en) * 1991-04-25 1993-07-06 National Research Council Of Canada Immunoassay for detecting group b streptococcus
DE69432658T2 (de) * 1993-03-19 2004-04-08 Gunnar Lindahl Rib-protein, ein oberflächenprotein welches immunität gegen viele streptococcus-stämme der gruppe b verleiht, reinigungsverfahren für das rib-protein, testsatz und pharmazeutische zusammenstellung (arznei)
US5595740A (en) * 1994-05-16 1997-01-21 University Of Florida Cloning of non-IgA FC binding forms of the group B streptococcal beta antigens
CN1142229A (zh) * 1994-11-01 1997-02-05 麒麟麦酒株式会社 形成粘蛋白糖链的肽序列和修饰蛋白质使与粘蛋白糖链相连的方法
US6420135B1 (en) * 1996-10-31 2002-07-16 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
AP2000001886A0 (en) * 1998-02-20 2000-09-30 Iaf Biochem Int Group B streptococcus antigens.
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
WO2000006736A2 (en) 1998-07-27 2000-02-10 Microbial Technics Limited Nucleic acids and proteins from group b streptococcus
US6582706B1 (en) 1998-12-21 2003-06-24 Medimmune, Inc. Vaccine compositions comprising Streptococcus pneumoniae polypeptides having selected structural MOTIFS
EA007409B1 (ru) 1998-12-23 2006-10-27 Шайе Биокем Инк. Антигенные полипептиды стрептококков, способы их получения и применения
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
GB9921125D0 (en) 1999-09-07 1999-11-10 Microbial Technics Limited Proteins
ATE543906T1 (de) 2002-02-11 2012-02-15 Id Biomedical Corp Antigen von streptococcus aus der b-gruppe

Also Published As

Publication number Publication date
CN1297482A (zh) 2001-05-30
ES2540281T3 (es) 2015-07-09
OA11686A (en) 2005-01-12
WO1999042588A2 (en) 1999-08-26
US20130095498A1 (en) 2013-04-18
NO330491B1 (no) 2011-05-02
CA2321106A1 (en) 1999-08-26
ATE347600T1 (de) 2006-12-15
EP2280072A2 (en) 2011-02-02
US20030228323A1 (en) 2003-12-11
ID27482A (id) 2001-04-12
ZA991325B (en) 1999-08-20
NO20101682L (no) 2000-10-19
DE69934299D1 (de) 2007-01-18
TR200002437T2 (tr) 2000-11-21
IL137921A0 (en) 2001-10-31
CZ301056B6 (cs) 2009-10-29
DE69934299T2 (de) 2007-07-05
JP4637350B2 (ja) 2011-02-23
EP1054971B1 (en) 2006-12-06
EP2280072A3 (en) 2012-06-06
EP1757697A2 (en) 2007-02-28
EP1054971A2 (en) 2000-11-29
AU2505999A (en) 1999-09-06
HU228497B1 (en) 2013-03-28
US8580262B2 (en) 2013-11-12
NZ529854A (en) 2005-08-26
EA200000860A1 (ru) 2001-10-22
EP1757697A3 (en) 2007-05-30
EP2280072B1 (en) 2015-03-25
CN1944652A (zh) 2007-04-11
JP2009242403A (ja) 2009-10-22
HUP0102304A3 (en) 2008-03-28
US20110182923A1 (en) 2011-07-28
KR100771148B1 (ko) 2007-10-29
IL190018A (en) 2011-07-31
US20030031682A1 (en) 2003-02-13
CA2321106C (en) 2013-07-23
NO20004161L (no) 2000-10-19
KR20010034518A (ko) 2001-04-25
JP2002507396A (ja) 2002-03-12
ES2278436T3 (es) 2007-08-01
NO20004161D0 (no) 2000-08-18
US8226953B2 (en) 2012-07-24
IL190018A0 (en) 2008-08-07
AP2000001886A0 (en) 2000-09-30
WO1999042588A3 (en) 2000-03-23
US7914794B2 (en) 2011-03-29
CZ20003054A3 (cs) 2001-03-14
IL137921A (en) 2008-06-05
HUP0102304A1 (hu) 2001-10-28

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: YIDE BIOLOGICAL MEDICAL CO.,LTD.

Free format text: FORMER OWNER: SHIRE BIOCHEM INC.

Effective date: 20080104

C41 Transfer of patent application or patent right or utility model
C56 Change in the name or address of the patentee

Owner name: SHIRE BIOCHEM INC.

Free format text: FORMER NAME OR ADDRESS: BIOCHEM PHARMA INC.

CP01 Change in the name or title of a patent holder

Address after: Quebec

Patentee after: SHIRE BIOCHEM Inc.

Address before: Quebec

Patentee before: Biochem Pharma INC.

TR01 Transfer of patent right

Effective date of registration: 20080104

Address after: Quebec

Patentee after: ID BIOMEDICAL Corp.

Address before: Quebec

Patentee before: SHIRE BIOCHEM Inc.

CX01 Expiry of patent term

Granted publication date: 20060809

CX01 Expiry of patent term