EA200000860A1 - Выделенный полинуклеотид (варианты), полинуклеотид (варианты), вектор (варианты), клетка-хозяин (варианты), выделенный полипептид (варианты), способ его получения (варианты), вакцинная композиция (варианты), способ терапевтического или профилактического лечения стрептококковой бактериальной инфекции у животного (варианты), применение (варианты) - Google Patents
Выделенный полинуклеотид (варианты), полинуклеотид (варианты), вектор (варианты), клетка-хозяин (варианты), выделенный полипептид (варианты), способ его получения (варианты), вакцинная композиция (варианты), способ терапевтического или профилактического лечения стрептококковой бактериальной инфекции у животного (варианты), применение (варианты)Info
- Publication number
- EA200000860A1 EA200000860A1 EA200000860A EA200000860A EA200000860A1 EA 200000860 A1 EA200000860 A1 EA 200000860A1 EA 200000860 A EA200000860 A EA 200000860A EA 200000860 A EA200000860 A EA 200000860A EA 200000860 A1 EA200000860 A1 EA 200000860A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- variants
- options
- bacterial infection
- polynucleotides
- polypeptide
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 208000035143 Bacterial infection Diseases 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 title abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 2
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 241000193990 Streptococcus sp. 'group B' Species 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010061372 Streptococcal infection Diseases 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Представлены белки Streptococcus группы B (GBS) и кодирующие их полинуклеотиды. Данные белки являются антигенными и вследствие этого используются как вакцинные компоненты для профилактики или терапии стрептококковых инфекций у животных. Кроме того описаны рекомбинантные способы получения белковых антигенов, а также диагностические анализы для детекции стрептококковой бактериальной инфекции.Отчет о международном поиске был опубликован 2000.03.23.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7542598P | 1998-02-20 | 1998-02-20 | |
PCT/CA1999/000114 WO1999042588A2 (en) | 1998-02-20 | 1999-02-17 | Group b streptococcus antigens |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200000860A1 true EA200000860A1 (ru) | 2001-10-22 |
Family
ID=22125658
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200000860A EA200000860A1 (ru) | 1998-02-20 | 1999-02-17 | Выделенный полинуклеотид (варианты), полинуклеотид (варианты), вектор (варианты), клетка-хозяин (варианты), выделенный полипептид (варианты), способ его получения (варианты), вакцинная композиция (варианты), способ терапевтического или профилактического лечения стрептококковой бактериальной инфекции у животного (варианты), применение (варианты) |
Country Status (22)
Country | Link |
---|---|
US (4) | US20030031682A1 (ru) |
EP (3) | EP1054971B1 (ru) |
JP (2) | JP4637350B2 (ru) |
KR (1) | KR100771148B1 (ru) |
CN (2) | CN1944652A (ru) |
AP (1) | AP2000001886A0 (ru) |
AT (1) | ATE347600T1 (ru) |
AU (1) | AU2505999A (ru) |
CA (1) | CA2321106C (ru) |
CZ (1) | CZ301056B6 (ru) |
DE (1) | DE69934299T2 (ru) |
EA (1) | EA200000860A1 (ru) |
ES (2) | ES2540281T3 (ru) |
HU (1) | HU228497B1 (ru) |
ID (1) | ID27482A (ru) |
IL (3) | IL137921A0 (ru) |
NO (2) | NO330491B1 (ru) |
NZ (1) | NZ529854A (ru) |
OA (1) | OA11686A (ru) |
TR (1) | TR200002437T2 (ru) |
WO (1) | WO1999042588A2 (ru) |
ZA (1) | ZA991325B (ru) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AP2000001886A0 (en) * | 1998-02-20 | 2000-09-30 | Iaf Biochem Int | Group B streptococcus antigens. |
CA2337102A1 (en) * | 1998-07-27 | 2000-02-10 | Richard William Falla Le Page | Nucleic acids and proteins from group b streptococcus |
US7098182B2 (en) | 1998-07-27 | 2006-08-29 | Microbial Technics Limited | Nucleic acids and proteins from group B streptococcus |
US6890539B2 (en) | 1998-12-22 | 2005-05-10 | Microscience, Ltd. | Genes and proteins, and their use |
EP1141308B1 (en) | 1998-12-22 | 2007-02-07 | Microscience Limited | Group b streptococcus proteins, and their use |
GB0105922D0 (en) * | 2001-03-09 | 2001-04-25 | Microscience Ltd | Genes and proteins, and their use |
US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
CA2382795A1 (en) * | 1999-08-25 | 2001-03-01 | Medimmune, Inc. | Homologs of a pneumococcal protein and fragments for vaccines |
US6833356B1 (en) | 1999-08-25 | 2004-12-21 | Medimmune, Inc. | Pneumococcal protein homologs and fragments for vaccines |
EP1294771B1 (en) | 2000-06-12 | 2008-10-29 | University Of Saskatchewan | Chimeric GapC protein from Streptococcus and its use in vaccination and diagnosis |
US6833134B2 (en) | 2000-06-12 | 2004-12-21 | University Of Saskacthewan | Immunization of dairy cattle with GapC protein against Streptococcus infection |
DK1332155T3 (da) * | 2000-06-12 | 2007-02-26 | Univ Saskatchewan | Vaccination af malkekvæg med GapC protein mod streptokokinfektion |
US6866855B2 (en) | 2000-06-12 | 2005-03-15 | University Of Saskatchewan | Immunization of dairy cattle with GapC protein against Streptococcus infection |
EP1734050A3 (en) * | 2000-06-12 | 2012-12-05 | University Of Saskatchewan | Immunization of dairy cattle with GapC protein against streptococcus infection |
WO2002031156A2 (en) | 2000-10-13 | 2002-04-18 | Shire Biochem Inc. | Bvh-a2 and bvh-a3 antigens of group b streptococcus |
MXPA03003690A (es) | 2000-10-27 | 2004-05-05 | Chiron Spa | Acidos nucleicos y proteinas de los grupos a y b de estreptococos. |
AU1686302A (en) * | 2000-12-21 | 2002-07-01 | Shire Biochem Inc | Streptococcus pyogenes antigens and corresponding dna fragments |
FR2824074A1 (fr) * | 2001-04-26 | 2002-10-31 | Pasteur Institut | Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques |
CA2475821C (en) * | 2002-02-11 | 2011-12-13 | Shire Biochem Inc. | Group b streptococcus antigens |
GB0210128D0 (en) * | 2002-05-02 | 2002-06-12 | Chiron Spa | Nucleic acids and proteins from streptococcus groups A & B |
EP1648500B1 (en) | 2003-07-31 | 2014-07-09 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions for streptococcus pyogenes |
US8945589B2 (en) | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
EP2612679A1 (en) | 2004-07-29 | 2013-07-10 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
JP2008544949A (ja) | 2004-10-08 | 2008-12-11 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 化膿性レンサ球菌のための免疫激性組成物および治療用組成物 |
CA2597170A1 (en) * | 2005-02-08 | 2006-08-17 | Id Biomedical Corporation Of Quebec C.O.B. As Glaxosmithkline Biological S North America | Pharmaceutical compositions |
GB0605247D0 (en) * | 2006-03-15 | 2006-04-26 | Chiron Srl | Compositions and methods for immunisation |
KR101621837B1 (ko) | 2007-09-12 | 2016-05-17 | 노파르티스 아게 | Gas57 돌연변이 항원 및 gas57 항체 |
CN104292312A (zh) | 2007-12-21 | 2015-01-21 | 诺华股份有限公司 | 链球菌溶血素o的突变形式 |
CN102304185A (zh) * | 2011-09-02 | 2012-01-04 | 黑龙江八一农垦大学 | 预防奶牛乳房炎的融合蛋白sip-trap及制备方法和应用 |
EP2949340A1 (en) * | 2014-05-30 | 2015-12-02 | IDT Biologika GmbH | Vaccine composition against Streptococcus suis infection |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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US4431739A (en) | 1979-11-05 | 1984-02-14 | Genentech, Inc. | Transformant bacterial culture capable of expressing heterologous protein |
US4425437A (en) | 1979-11-05 | 1984-01-10 | Genentech, Inc. | Microbial polypeptide expression vehicle |
US5302386A (en) * | 1986-04-16 | 1994-04-12 | Brigham And Women's Hospital, Inc. | Bacterial antigens, antibodies, vaccines and methods of manufacture |
US5472696A (en) * | 1988-02-26 | 1995-12-05 | Univ. Of Florida Research Foundation, Inc. | Antigen of group B streptococci |
US5648241A (en) * | 1989-09-15 | 1997-07-15 | The General Hospital Corporation | Conjugate vaccine against group B streptococcus |
US5679768A (en) * | 1991-02-15 | 1997-10-21 | Uab Research Foundation | Epitopic regions of pneumococcal surface protein A |
US5225331A (en) * | 1991-04-25 | 1993-07-06 | National Research Council Of Canada | Immunoassay for detecting group b streptococcus |
CA2158658A1 (en) | 1993-03-19 | 1994-09-29 | Margaretha Stalhammar-Carlemalm | Protein rib, a cell surface protein that confers immunity to many strains of the group b streptococcus; process for purification of the protein, reagent kit and pharmaceutical composition |
US5595740A (en) * | 1994-05-16 | 1997-01-21 | University Of Florida | Cloning of non-IgA FC binding forms of the group B streptococcal beta antigens |
EP0754703A4 (en) * | 1994-11-01 | 1999-11-24 | Kirin Brewery | PEPTIDE SEQUENCE FORMING A MUCIN CHAIN AND TECHNIQUE FOR MODIFYING THE PROTEIN TO BE LINKED TO THE MUCIN CHAIN |
EP0941335A2 (en) * | 1996-10-31 | 1999-09-15 | Human Genome Sciences | Streptococcus pneumoniae polynucleotides and sequences |
AP2000001886A0 (en) * | 1998-02-20 | 2000-09-30 | Iaf Biochem Int | Group B streptococcus antigens. |
US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
CA2337102A1 (en) | 1998-07-27 | 2000-02-10 | Richard William Falla Le Page | Nucleic acids and proteins from group b streptococcus |
JP4689044B2 (ja) | 1998-12-21 | 2011-05-25 | メディミューン,インコーポレーテッド | ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片 |
US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
KR100802198B1 (ko) | 1998-12-23 | 2008-02-11 | 샤이어 바이오켐 인코포레이티드 | 신규한 스트렙토코커스 항원 |
GB9921125D0 (en) | 1999-09-07 | 1999-11-10 | Microbial Technics Limited | Proteins |
CA2475821C (en) | 2002-02-11 | 2011-12-13 | Shire Biochem Inc. | Group b streptococcus antigens |
-
1999
- 1999-02-17 AP APAP/P/2000/001886A patent/AP2000001886A0/en unknown
- 1999-02-17 IL IL13792199A patent/IL137921A0/xx active IP Right Grant
- 1999-02-17 ES ES10180962.2T patent/ES2540281T3/es not_active Expired - Lifetime
- 1999-02-17 OA OA1200000228A patent/OA11686A/en unknown
- 1999-02-17 AT AT99904646T patent/ATE347600T1/de not_active IP Right Cessation
- 1999-02-17 KR KR1020007009237A patent/KR100771148B1/ko not_active IP Right Cessation
- 1999-02-17 WO PCT/CA1999/000114 patent/WO1999042588A2/en active Application Filing
- 1999-02-17 TR TR2000/02437T patent/TR200002437T2/xx unknown
- 1999-02-17 ES ES99904646T patent/ES2278436T3/es not_active Expired - Lifetime
- 1999-02-17 CA CA2321106A patent/CA2321106C/en not_active Expired - Lifetime
- 1999-02-17 EA EA200000860A patent/EA200000860A1/ru unknown
- 1999-02-17 DE DE69934299T patent/DE69934299T2/de not_active Expired - Lifetime
- 1999-02-17 ID IDW20001856A patent/ID27482A/id unknown
- 1999-02-17 JP JP2000532528A patent/JP4637350B2/ja not_active Expired - Lifetime
- 1999-02-17 EP EP99904646A patent/EP1054971B1/en not_active Expired - Lifetime
- 1999-02-17 EP EP10180962.2A patent/EP2280072B1/en not_active Expired - Lifetime
- 1999-02-17 CN CNA2006100913640A patent/CN1944652A/zh active Pending
- 1999-02-17 AU AU25059/99A patent/AU2505999A/en not_active Abandoned
- 1999-02-17 EP EP20060022306 patent/EP1757697A3/en not_active Withdrawn
- 1999-02-17 CZ CZ20003054A patent/CZ301056B6/cs not_active IP Right Cessation
- 1999-02-17 CN CNB998052485A patent/CN1268745C/zh not_active Expired - Lifetime
- 1999-02-17 HU HU0102304A patent/HU228497B1/hu unknown
- 1999-02-18 ZA ZA9901325A patent/ZA991325B/xx unknown
- 1999-02-18 US US09/252,088 patent/US20030031682A1/en active Pending
-
2000
- 2000-08-17 IL IL137921A patent/IL137921A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004161A patent/NO330491B1/no not_active IP Right Cessation
-
2003
- 2003-01-13 US US10/340,792 patent/US7914794B2/en not_active Expired - Lifetime
- 2003-11-28 NZ NZ529854A patent/NZ529854A/en not_active IP Right Cessation
-
2008
- 2008-03-09 IL IL190018A patent/IL190018A/en not_active IP Right Cessation
-
2009
- 2009-06-02 JP JP2009132976A patent/JP2009242403A/ja active Pending
-
2010
- 2010-11-30 NO NO20101682A patent/NO20101682L/no not_active Application Discontinuation
- 2010-12-28 US US12/980,172 patent/US8226953B2/en not_active Expired - Fee Related
-
2012
- 2012-07-16 US US13/550,363 patent/US8580262B2/en not_active Expired - Fee Related
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