CN1223340C - 电纺丝的药物组合物 - Google Patents

电纺丝的药物组合物 Download PDF

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Publication number
CN1223340C
CN1223340C CNB018042422A CN01804242A CN1223340C CN 1223340 C CN1223340 C CN 1223340C CN B018042422 A CNB018042422 A CN B018042422A CN 01804242 A CN01804242 A CN 01804242A CN 1223340 C CN1223340 C CN 1223340C
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Prior art keywords
poly
activating agent
cellulose
agent
water
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Expired - Fee Related
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CNB018042422A
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English (en)
Chinese (zh)
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CN1396823A (zh
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弗朗西斯·伊格内修斯
约翰·M·鲍多尼
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SmithKline Beecham Corp
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SmithKline Beecham Corp
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    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D01D5/0038—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/0023—Electro-spinning characterised by the initial state of the material the material being a polymer melt
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Textile Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Mechanical Engineering (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
CNB018042422A 2000-01-28 2001-01-25 电纺丝的药物组合物 Expired - Fee Related CN1223340C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17868200P 2000-01-28 2000-01-28
US60/178,682 2000-01-28

Publications (2)

Publication Number Publication Date
CN1396823A CN1396823A (zh) 2003-02-12
CN1223340C true CN1223340C (zh) 2005-10-19

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CNB018042422A Expired - Fee Related CN1223340C (zh) 2000-01-28 2001-01-25 电纺丝的药物组合物

Country Status (18)

Country Link
EP (1) EP1251829A4 (ja)
JP (1) JP2003521493A (ja)
KR (1) KR100806412B1 (ja)
CN (1) CN1223340C (ja)
AR (1) AR028204A1 (ja)
AU (1) AU772830B2 (ja)
BR (1) BR0107869A (ja)
CA (1) CA2396640A1 (ja)
HU (1) HUP0301130A3 (ja)
IL (1) IL150642A0 (ja)
MX (1) MXPA02007298A (ja)
MY (1) MY129356A (ja)
NO (1) NO20023338L (ja)
NZ (1) NZ519992A (ja)
PL (1) PL356924A1 (ja)
TW (1) TWI289061B (ja)
WO (1) WO2001054667A1 (ja)
ZA (1) ZA200205989B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107072937A (zh) * 2014-06-10 2017-08-18 德姆特里特有限公司 包含通过水电动力得到的纤维的用于将特定剂量的活性物质施用于皮肤或粘膜的组合物

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JP4787585B2 (ja) * 2005-09-29 2011-10-05 帝人株式会社 静電紡糸法による繊維構造体の製造方法
CN100556399C (zh) * 2005-12-23 2009-11-04 中国科学院广州化学研究所 一种肠靶向型药物控释纤维及其制备方法
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