CN113930442A - 产生pufa的材料和方法及含有pufa的组合物 - Google Patents

产生pufa的材料和方法及含有pufa的组合物 Download PDF

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Publication number
CN113930442A
CN113930442A CN202111139791.2A CN202111139791A CN113930442A CN 113930442 A CN113930442 A CN 113930442A CN 202111139791 A CN202111139791 A CN 202111139791A CN 113930442 A CN113930442 A CN 113930442A
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CN
China
Prior art keywords
plant
content
desaturase
dna
oil
Prior art date
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Pending
Application number
CN202111139791.2A
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English (en)
Chinese (zh)
Inventor
T·森杰
L·马蒂
I·孔策
H·A·黑特尔
S·布雷默
S·布雷奇尔
J·鲍尔
P·弗伦坦
S·斯蒂姆内
J·林德伯格伊尔马兹
J·麦克尔维尔
D·雷恩
C·安德烈
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioriginal Food and Science Corp
BASF Plant Science Co GmbH
Original Assignee
Bioriginal Food and Science Corp
BASF Plant Science Co GmbH
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54601758&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN113930442(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bioriginal Food and Science Corp, BASF Plant Science Co GmbH filed Critical Bioriginal Food and Science Corp
Publication of CN113930442A publication Critical patent/CN113930442A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/02—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by the production or working-up
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19003—Linoleoyl-CoA desaturase (1.14.19.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19006—DELTA12-fatty-acid desaturase (1.14.19.6), i.e. oleoyl-CoA DELTA12 desaturase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01003—Long-chain-fatty-acid-CoA ligase (6.2.1.3)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Animal Husbandry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202111139791.2A 2014-11-14 2015-11-13 产生pufa的材料和方法及含有pufa的组合物 Pending CN113930442A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462079622P 2014-11-14 2014-11-14
US62/079,622 2014-11-14
US201562234373P 2015-09-29 2015-09-29
US62/234,373 2015-09-29
CN201580073394.6A CN107532179B (zh) 2014-11-14 2015-11-13 产生pufa的材料和方法及含有pufa的组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580073394.6A Division CN107532179B (zh) 2014-11-14 2015-11-13 产生pufa的材料和方法及含有pufa的组合物

Publications (1)

Publication Number Publication Date
CN113930442A true CN113930442A (zh) 2022-01-14

Family

ID=54601758

Family Applications (6)

Application Number Title Priority Date Filing Date
CN202111139791.2A Pending CN113930442A (zh) 2014-11-14 2015-11-13 产生pufa的材料和方法及含有pufa的组合物
CN202210113594.1A Pending CN115094081A (zh) 2014-11-14 2015-11-13 增加种子油中生育酚含量的材料和方法
CN201580061517.4A Pending CN107257630A (zh) 2014-11-14 2015-11-13 包含pufa的植物脂质的修饰
CN201580073433.2A Active CN107429256B (zh) 2014-11-14 2015-11-13 增加种子油中生育酚含量的材料和方法
CN201580073289.2A Active CN107580629B (zh) 2014-11-14 2015-11-13 芸苔属事件lbflfk和lbfdau及其检测方法
CN201580073394.6A Active CN107532179B (zh) 2014-11-14 2015-11-13 产生pufa的材料和方法及含有pufa的组合物

Family Applications After (5)

Application Number Title Priority Date Filing Date
CN202210113594.1A Pending CN115094081A (zh) 2014-11-14 2015-11-13 增加种子油中生育酚含量的材料和方法
CN201580061517.4A Pending CN107257630A (zh) 2014-11-14 2015-11-13 包含pufa的植物脂质的修饰
CN201580073433.2A Active CN107429256B (zh) 2014-11-14 2015-11-13 增加种子油中生育酚含量的材料和方法
CN201580073289.2A Active CN107580629B (zh) 2014-11-14 2015-11-13 芸苔属事件lbflfk和lbfdau及其检测方法
CN201580073394.6A Active CN107532179B (zh) 2014-11-14 2015-11-13 产生pufa的材料和方法及含有pufa的组合物

Country Status (14)

Country Link
US (12) US11613761B1 (enExample)
EP (4) EP3218499B1 (enExample)
JP (7) JP6974168B2 (enExample)
KR (2) KR20170099884A (enExample)
CN (6) CN113930442A (enExample)
AU (12) AU2015344993C9 (enExample)
CA (6) CA2967131A1 (enExample)
CL (4) CL2017001225A1 (enExample)
EC (3) ECSP17036764A (enExample)
MX (4) MX388387B (enExample)
MY (1) MY184649A (enExample)
PH (4) PH12017500880A1 (enExample)
SG (1) SG11201703858YA (enExample)
WO (6) WO2016075327A2 (enExample)

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AR109245A1 (es) * 2016-05-12 2018-11-14 Basf Plant Science Co Gmbh Métodos para optimizar la producción de metabolitos en plantas genéticamente modificadas y para procesar estas plantas
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EP3586643A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586641A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
CA3110651A1 (en) * 2018-09-07 2020-03-12 Basf Plant Science Company Gmbh Improved method for the production of high levels of pufa in plants
CA3057917A1 (en) 2018-10-16 2020-04-16 Monsanto Technology Llc Brassica event mon94100 and methods of use thereof
CA3129494A1 (en) * 2019-02-14 2020-08-20 Cargill, Incorporated Brassica plants producing elevated levels of polyunsaturated fatty acids
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CN110699462B (zh) * 2019-11-06 2023-08-18 中国科学院南海海洋研究所 一种砗蚝微卫星位点及鉴定引物
AU2021373697A1 (en) * 2020-11-04 2023-06-08 Basf Plant Science Company Gmbh Harvest management
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CN113475400B (zh) * 2021-08-03 2022-07-12 吉安市林业科学研究所 双牌泡果荠的人工培养技术
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KR102721490B1 (ko) * 2022-02-17 2024-10-24 대한민국 유전자변형 면화를 검정하기 위한 양성대조군 플라스미드 및 이를 이용한 유전자변형 면화의 검정방법
KR102721484B1 (ko) * 2022-02-17 2024-10-24 대한민국 유전자변형 유채를 검정하기 위한 양성대조군 플라스미드 및 이를 이용한 유전자변형 유채의 검정방법
WO2024005187A1 (ja) 2022-07-01 2024-01-04 田辺三菱製薬株式会社 組成物、およびエダラボンの応答可能性の評価方法
CN117204282A (zh) * 2023-09-08 2023-12-12 中国农业科学院油料作物研究所 一种利用敌草快提高油菜籽生育酚含量的方法
CN119193346A (zh) * 2024-11-26 2024-12-27 南京师范大学 一种过表达溶血磷脂酸酰基转移酶基因的裂殖壶菌基因工程菌株及其构建方法和应用

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