BRPI0911892A8 - polinucleotídeo, vetor, célula hospedeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composição de óleo, lipídio ou ácido graxo - Google Patents

polinucleotídeo, vetor, célula hospedeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composição de óleo, lipídio ou ácido graxo

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Publication number
BRPI0911892A8
BRPI0911892A8 BRPI0911892A BRPI0911892A BRPI0911892A8 BR PI0911892 A8 BRPI0911892 A8 BR PI0911892A8 BR PI0911892 A BRPI0911892 A BR PI0911892A BR PI0911892 A BRPI0911892 A BR PI0911892A BR PI0911892 A8 BRPI0911892 A8 BR PI0911892A8
Authority
BR
Brazil
Prior art keywords
polypeptide
desaturase
lipid
antibody
vector
Prior art date
Application number
BRPI0911892A
Other languages
English (en)
Inventor
Bauer Joerg
A Napier Johnathan
Sayanova Olga
Original Assignee
Rothamsted Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rothamsted Res Ltd filed Critical Rothamsted Res Ltd
Publication of BRPI0911892A2 publication Critical patent/BRPI0911892A2/pt
Publication of BRPI0911892A8 publication Critical patent/BRPI0911892A8/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6481Phosphoglycerides
BRPI0911892A 2008-04-30 2009-04-29 polinucleotídeo, vetor, célula hospedeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composição de óleo, lipídio ou ácido graxo BRPI0911892A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08155461 2008-04-30
PCT/EP2009/055210 WO2009133145A1 (en) 2008-04-30 2009-04-29 Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms

Publications (2)

Publication Number Publication Date
BRPI0911892A2 BRPI0911892A2 (pt) 2016-09-20
BRPI0911892A8 true BRPI0911892A8 (pt) 2018-06-26

Family

ID=40809894

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911892A BRPI0911892A8 (pt) 2008-04-30 2009-04-29 polinucleotídeo, vetor, célula hospedeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composição de óleo, lipídio ou ácido graxo

Country Status (8)

Country Link
US (1) US8785727B2 (pt)
EP (1) EP2281051B1 (pt)
CN (1) CN102066564B (pt)
AU (1) AU2009242130B2 (pt)
BR (1) BRPI0911892A8 (pt)
CA (1) CA2723072C (pt)
ES (1) ES2536796T3 (pt)
WO (1) WO2009133145A1 (pt)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
CA2533613C (en) 2003-08-01 2020-03-10 Basf Plant Science Gmbh Nucleic acid encoding a .delta.5-elongase polypeptide derived from ostreococcus tauri, methods and uses thereof
US9458436B2 (en) 2004-02-27 2016-10-04 Basf Plant Science Gmbh Method for producing polyunsaturated fatty acids in transgenic plants
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
US8455035B2 (en) 2008-04-25 2013-06-04 Basf Plant Science Gmbh Plant seed oil
BR122021003835B1 (pt) 2008-11-18 2022-02-08 Grains Research And Development Corporation Polinucleotídeo isolado e/ou exógeno que não ocorre de forma natural, vetor compreendendo o referido polinucleotídeo e método de produção de óleo contendo ácidos graxos insaturados
JP2012529277A (ja) * 2009-06-08 2012-11-22 ロザムステッド リサーチ リミテッド 新規の脂肪酸伸長成分およびその使用
US9493520B2 (en) * 2009-07-17 2016-11-15 Basf Plant Science Company Gmbh Fatty acid desaturases and elongases and uses thereof
EP2504438A1 (en) 2009-11-24 2012-10-03 BASF Plant Science Company GmbH Novel fatty acid elongase and uses thereof
EP2504427B1 (en) 2009-11-24 2018-06-27 BASF Plant Science Company GmbH Novel fatty acid desaturase and uses thereof
EP2649180A4 (en) 2010-12-06 2014-05-21 Basf Plant Science Co Gmbh PROCESS FOR PRODUCING SYNTHETIC PROMOTERS WITH DEFINED SPECIFICITY
WO2013153404A1 (en) 2012-04-12 2013-10-17 Rothamsted Research Ltd Production of omega-3 long chain polyunsaturated fatty acids
UA117223C2 (uk) 2012-06-15 2018-07-10 Коммонвелт Сайнтіфік Енд Індастріел Рісерч Організейшн Спосіб продукування довголанцюгових поліненасичених жирних кислот у рослинній клітині
SG11201604871VA (en) 2013-12-18 2016-07-28 Commw Scient Ind Res Org Lipid comprising long chain polyunsaturated fatty acids
CN103834672B (zh) * 2014-03-17 2015-12-09 昆明理工大学 一种δ12-脂肪酸脱氢酶基因及其应用
SG11201610596PA (en) 2014-06-27 2017-01-27 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
CN115094081A (zh) 2014-11-14 2022-09-23 巴斯夫植物科学有限公司 增加种子油中生育酚含量的材料和方法
CN113249442B (zh) * 2021-05-19 2023-03-14 中国科学院海洋研究所 一种筛查牡蛎不饱和脂肪酸含量相关甲基化修饰基因的方法

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PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
JPH07501701A (ja) 1991-12-04 1995-02-23 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 植物由来の脂肪酸不飽和化酵素遺伝子
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
WO1994011516A1 (en) 1992-11-17 1994-05-26 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
US7205457B1 (en) 1993-02-05 2007-04-17 Monsanto Technology Llc Altered linolenic and linoleic acid content in plants
ATE273395T1 (de) 1993-12-28 2004-08-15 Kirin Brewery Gen für die fettsäure-desaturase, besagtes gen enthaltender vektor, eine pflanze, in die besagtes gen eingebracht ist, und ein verfahren zur schaffung besagter pflanze
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Also Published As

Publication number Publication date
EP2281051B1 (en) 2015-03-11
CN102066564A (zh) 2011-05-18
WO2009133145A1 (en) 2009-11-05
CN102066564B (zh) 2015-02-11
CA2723072C (en) 2017-01-10
US8785727B2 (en) 2014-07-22
BRPI0911892A2 (pt) 2016-09-20
AU2009242130B2 (en) 2013-09-19
ES2536796T3 (es) 2015-05-28
EP2281051A1 (en) 2011-02-09
US20110138490A1 (en) 2011-06-09
AU2009242130A1 (en) 2009-11-05
CA2723072A1 (en) 2009-11-05

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