CL2012003644A1 - Polinucleotido que comprende una aciltransferasas; celula huesped que comprende dicho polinucleotido; metodo para la fabricacion de un polipeptido ; metodo para la fabricacion de acidos grasos poliinsaturados. - Google Patents

Polinucleotido que comprende una aciltransferasas; celula huesped que comprende dicho polinucleotido; metodo para la fabricacion de un polipeptido ; metodo para la fabricacion de acidos grasos poliinsaturados.

Info

Publication number
CL2012003644A1
CL2012003644A1 CL2012003644A CL2012003644A CL2012003644A1 CL 2012003644 A1 CL2012003644 A1 CL 2012003644A1 CL 2012003644 A CL2012003644 A CL 2012003644A CL 2012003644 A CL2012003644 A CL 2012003644A CL 2012003644 A1 CL2012003644 A1 CL 2012003644A1
Authority
CL
Chile
Prior art keywords
polynucleotide
manufacture
acyltransferases
polypeptide
host cell
Prior art date
Application number
CL2012003644A
Other languages
English (en)
Inventor
Toralf Senger
Laurent Marty
Sten Stymne
Yilmaz Jenny Lindberg
Johnathan Napier
Olga Sayanova
Richard Haslam
Ruiz Lopez Noemi
Original Assignee
Basf Plant Science Co Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Plant Science Co Gmbh filed Critical Basf Plant Science Co Gmbh
Publication of CL2012003644A1 publication Critical patent/CL2012003644A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/04—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
    • C11C1/045—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis using enzymes or microorganisms, living or dead
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/18—Lipids
    • A23V2250/186—Fatty acids
    • A23V2250/1862—Arachidonic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/18—Lipids
    • A23V2250/186—Fatty acids
    • A23V2250/1868—Docosahexaenoic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/18—Lipids
    • A23V2250/186—Fatty acids
    • A23V2250/187—Eicosapentaenoic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/18—Lipids
    • A23V2250/186—Fatty acids
    • A23V2250/1882—Polyunsaturated fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CL2012003644A 2010-06-25 2012-12-21 Polinucleotido que comprende una aciltransferasas; celula huesped que comprende dicho polinucleotido; metodo para la fabricacion de un polipeptido ; metodo para la fabricacion de acidos grasos poliinsaturados. CL2012003644A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35843110P 2010-06-25 2010-06-25
EP10167342 2010-06-25

Publications (1)

Publication Number Publication Date
CL2012003644A1 true CL2012003644A1 (es) 2013-08-02

Family

ID=44453977

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012003644A CL2012003644A1 (es) 2010-06-25 2012-12-21 Polinucleotido que comprende una aciltransferasas; celula huesped que comprende dicho polinucleotido; metodo para la fabricacion de un polipeptido ; metodo para la fabricacion de acidos grasos poliinsaturados.

Country Status (7)

Country Link
US (2) US9388437B2 (es)
EP (1) EP2585603B1 (es)
AU (1) AU2011269059B2 (es)
CA (1) CA2804925A1 (es)
CL (1) CL2012003644A1 (es)
NO (1) NO2585603T3 (es)
WO (1) WO2011161093A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2909304A4 (en) * 2012-10-16 2016-09-21 Exxonmobil Res & Eng Co DGAT GENE AND METHOD FOR USE IN TRIGLYCERIDE PRODUCTION IN RECOMBINANT MICROORGANISMS
AU2012396236B2 (en) 2012-12-06 2015-10-15 Exxonmobil Research And Engineering Company DGAT genes comprising pleckstrin homology domains and use in recombinant microorganisms
CA2893409A1 (en) * 2012-12-21 2014-06-26 E. I. Du Pont De Nemours And Company Recombinant microbial cells that produce at least 28% eicosapentaenoic acid as dry cell weight
JP2016054703A (ja) * 2014-09-11 2016-04-21 花王株式会社 ラウリン酸の製造方法
WO2016075303A1 (en) 2014-11-14 2016-05-19 Basf Plant Science Company Gmbh Brassica events lbflfk and lbfdau and methods for detection thereof
JP6580912B2 (ja) 2015-09-11 2019-09-25 花王株式会社 脂質の製造方法
CN113423837B (zh) 2019-02-14 2024-08-13 巴斯夫植物科学有限公司 产生提高的水平的多不饱和脂肪酸的芸苔属植物
WO2022129619A1 (en) * 2020-12-18 2022-06-23 Rothamsted Research Limited Increasing the accumulation of epa and dha in recombinant camelina

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
DK162399C (da) 1986-01-28 1992-03-23 Danisco Fremgangsmaade til ekspression af gener i baelgplanteceller, dna-fragment, rekombineret dna-fragment samt plasmid til brug ved udoevelsen af fremgangsmaaden
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
NZ228320A (en) 1988-03-29 1991-06-25 Du Pont Nucleic acid promoter fragments of the promoter region homologous to the em gene of wheat, dna constructs therefrom and plants thereof
DE3843628A1 (de) 1988-12-21 1990-07-05 Inst Genbiologische Forschung Wundinduzierbare und kartoffelknollenspezifische transkriptionale regulation
EP0388186A1 (en) 1989-03-17 1990-09-19 E.I. Du Pont De Nemours And Company External regulation of gene expression
EP0472722B1 (en) 1990-03-16 2003-05-21 Calgene LLC Dnas encoding plant desaturases and their uses
ATE205530T1 (de) 1990-03-16 2001-09-15 Calgene Llc Neue sequenzen vorzugsweise exprimiert während der frühen keimentwicklung und darauf bezogene methoden
US5187267A (en) 1990-06-19 1993-02-16 Calgene, Inc. Plant proteins, promoters, coding sequences and use
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
WO1993010241A1 (en) 1991-11-20 1993-05-27 Calgene, Inc. FATTY ACYL-CoA: FATTY ALCOHOL O-ACYLTRANSFERASES
US5952544A (en) 1991-12-04 1999-09-14 E. I. Du Pont De Nemours And Company Fatty acid desaturase genes from plants
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
DE69331055T2 (de) 1992-04-13 2002-06-20 Syngenta Ltd., Haselmere Dna-konstruktionen und diese enthaltende pflanzen
EP0668919B1 (en) 1992-11-17 2003-06-04 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
GB9225845D0 (en) 1992-12-10 1993-02-03 Nickerson Biocem Ltd Modified plants
CA2150133A1 (en) 1993-02-05 1994-08-18 Vincent Jean-Marie Armel Arondel Altered linolenic and linoleic acid content in plants
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
JP3313724B2 (ja) 1993-12-28 2002-08-12 麒麟麦酒株式会社 脂肪酸の不飽和化酸素遺伝子，当該遺伝子を含むベクター，当該遺伝子が導入された植物及びその作出方法
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US5910630A (en) 1994-04-06 1999-06-08 Davies; Huw Maelor Plant lysophosphatidic acid acyltransferases
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
GB9421286D0 (en) 1994-10-21 1994-12-07 Danisco Promoter
GB9502468D0 (en) 1995-02-09 1995-03-29 Gene Shears Pty Ltd DNA Sequence
RU2192466C2 (ru) 1995-08-10 2002-11-10 Ратгерс Юниверсити Кодируемая ядерной днк система транскрипции в пластидах высших растений
WO1997021340A1 (en) 1995-12-14 1997-06-19 Cargill, Incorporated Plants having mutant sequences that confer altered fatty acid profiles
EP0794250A1 (en) 1996-03-04 1997-09-10 Soremartec S.A. Isolation and sequencing of the hazel FAd2-N gene
US6033883A (en) 1996-12-18 2000-03-07 Kosan Biosciences, Inc. Production of polyketides in bacteria and yeast
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
JP4087460B2 (ja) 1997-04-11 2008-05-21 カルジーン エル エル シー 植物における長鎖多不飽和脂肪酸の合成のための方法および組成物
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
WO1998054302A2 (en) 1997-05-27 1998-12-03 Icos Corporation Human lysophosphatidic acid acyltransferase
WO1998054303A1 (en) 1997-05-27 1998-12-03 Cell Therapeutics, Inc. Mammalian lysophosphatidic acid acyltransferase
WO1998055625A1 (en) 1997-06-04 1998-12-10 Calgene, Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
EP0986647B1 (en) 1997-06-05 2006-04-19 Calgene LLC FATTY ACYL-CoA: FATTY ALCOHOL ACYLTRANSFERASES
CN1266460A (zh) 1997-06-05 2000-09-13 卡尔金有限责任公司 二酰甘油酰基转移酶蛋白
AU746032B2 (en) 1997-09-30 2002-04-11 Regents Of The University Of California, The Production of proteins in plant seeds
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
ATE325883T1 (de) 1998-03-11 2006-06-15 Syngenta Participations Ag Pflanzliche promotorsequenz aus plastiden
WO1999064616A2 (en) 1998-06-12 1999-12-16 Abbott Laboratories Polyunsaturated fatty acids in plants
WO2000018889A2 (en) 1998-09-25 2000-04-06 Calgene Llc Sequenzes of putative plant acyltransferases
EP1121150A4 (en) 1998-10-09 2003-06-04 Merck & Co Inc DELAT 6 FATTY ACID DESATURASE
CA2354672C (en) 1998-12-07 2012-10-02 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
AU776447B2 (en) 1999-06-07 2004-09-09 Basf Plant Science Gmbh Delta6-acetylenase and delta6-desaturase from ceratodon purpureus
CA2378423A1 (en) 1999-07-06 2001-01-11 Basf Plant Science Gmbh Plants expressing .delta.6-desaturase genes and oils from these plants containing pufas and method for producing unsaturated fatty acids
KR20020073580A (ko) 2000-02-09 2002-09-27 바스프 악티엔게젤샤프트 신규 연장효소 유전자 및 다가불포화 지방산의 제조 방법
WO2001085968A2 (en) 2000-05-09 2001-11-15 Bioriginal Food & Science Corp. Production of conjugated linoleic and linolenic acids in plants
JP4071622B2 (ja) 2000-09-28 2008-04-02 バイオリジナル フード アンド サイエンス コーポレーション 脂肪酸不飽和化酵素ファミリーのメンバーであるｆａｄ４、ｆａｄ５、ｆａｄ５−２およびｆａｄ６、ならびにそれらの使用方法
DE10102337A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
AU2002329522B2 (en) 2001-06-06 2008-05-22 Bioriginal Food & Science Corporation Flax (Linum usitatissimim L.) seed-specific promoters
WO2003064638A2 (de) 2002-01-30 2003-08-07 Basf Plant Science Gmbh Elongase-gen und verfahren zur herstellung mehrfach ungesättigter fettsäuren
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
JP4781817B2 (ja) 2002-12-19 2011-09-28 ユニバーシティ オブ ブリストル 多価不飽和脂肪酸類の製造方法
AU2004225838B2 (en) 2003-03-31 2009-11-05 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
BRPI0409209A (pt) 2003-04-08 2006-03-28 Basf Plant Science Gmbh seqüência de ácido nucleico isolado, construto de gene, vetor, organismo não-humano transgênico, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeos ou ácidos graxos ou uma fração dos mesmos, composição de óleo, de lipìdeo ou de ácido graxo, e, uso de óleo, de lipìdeos ou de ácidos graxos ou de composição de óleo, de lipìdeo ou de ácido graxo
BRPI0413073A (pt) 2003-08-01 2006-10-03 Basf Plant Science Gmbh processo para a produção de compostos, óleo, lipìdeo ou ácido graxo, ou uma fração dos mesmos, composição de óleo, lipìdeo ou ácido graxo, processo para a produção de óleos, lipìdeos ou composições de ácido graxo, uso de óleo, lipìdeo ou ácidos graxos ou de composições de óleo, lipìdeo ou ácido graxo ou de óleos, lipìdeos ou composições de ácido graxo, seqüência de ácido nucleico isolado, seqüência de aminoácidos, construção de gene, vetor, e, organismo não humano transgênico
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
DE102004063326A1 (de) 2004-12-23 2006-07-06 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
US7723574B2 (en) 2005-11-24 2010-05-25 Basf Plant Science Gmbh Process for the production of Δ5-unsaturated fatty acids in transgenic organisms
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
CA2647150A1 (en) * 2006-03-15 2007-09-20 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
CA2656786C (en) 2006-07-11 2019-07-02 Bioriginal Food & Science Corporation Fatty acid desaturases and uses thereof
EP2500420B1 (en) 2006-08-24 2016-06-22 BASF Plant Science GmbH Pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
PL2177605T3 (pl) 2006-10-06 2015-05-29 Basf Plant Science Gmbh Delta-5 desaturazy i sposób wytwarzania wielokrotnie nienasyconych kwasów tłuszczowych w organizmach transgenicznych innych niż człowiek
EP2176416B1 (de) 2007-07-31 2016-03-16 BASF Plant Science GmbH Elongasen und verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
DE112008001989A5 (de) 2007-07-31 2010-06-10 Basf Plant Science Gmbh Desaturasen und Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
EP3146836A1 (en) 2007-12-21 2017-03-29 National Research Council of Canada Diacylglycerol acyltransferase 2 genes and proteins encoded thereby from algae
EP2620500A3 (en) 2008-05-23 2014-01-08 E. I. du Pont de Nemours and Company DGAT genes from oleaginous organisms for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
BRPI0908694A2 (pt) 2008-05-23 2019-09-24 Du Pont ''sementes de grão de soja transgência e método para aumentar o teor de ácido graxo total de uma semente de grão de soja''
EP2821492A3 (en) 2009-05-13 2015-04-08 BASF Plant Science Company GmbH Acyltransferases and uses thereof in fatty acid production
WO2011161678A2 (en) * 2010-06-23 2011-12-29 Ben Gurion University Of The Negev Research And Development Authority Glycerol-3-phosphate acyltransferase and uses thereof

Also Published As

Publication number Publication date
WO2011161093A1 (en) 2011-12-29
US20130097733A1 (en) 2013-04-18
EP2585603A1 (en) 2013-05-01
AU2011269059B2 (en) 2016-01-28
US9388437B2 (en) 2016-07-12
CA2804925A1 (en) 2011-12-29
AU2011269059A1 (en) 2013-01-10
EP2585603B1 (en) 2017-12-20
US10208270B2 (en) 2019-02-19
US20160272951A1 (en) 2016-09-22
NO2585603T3 (es) 2018-05-19

Similar Documents

Publication Publication Date Title
CL2012003644A1 (es) Polinucleotido que comprende una aciltransferasas; celula huesped que comprende dicho polinucleotido; metodo para la fabricacion de un polipeptido ; metodo para la fabricacion de acidos grasos poliinsaturados.
CA3241340A1 (en) Lipid comprising long chain polyunsaturated fatty acids
EP3062785A4 (en) Enteric soft capsules comprising polyunsaturated fatty acids
BRPI0921467A2 (pt) Enzimas e métodos para produzir ácidos graxos ômega-3
CL2013001092A1 (es) Polinucleotido que codifica un polipeptido con actividad desaturasa; vector; celula huesped; dicho polipeptido; metodo de preparacion del polipeptido; y metodo para preparar acidos grasos poliinsaturados.
BRPI0920804A2 (pt) método para preparar alquil ésteres de ácido graxo.
BRPI0911606A2 (pt) Polipeptídeo e métodos para produzir triacilgliceróis compreendendo ácidos graxos modificados
ZA201405956B (en) Method for the preparation of triglycerides of medium-chain length fatty acids.
BRPI0923797A2 (pt) Método para produzir um éster.
EP2619298A4 (en) METHOD FOR CONCENTRATING OMEGA 3 FATTY ACIDS
EP2826561A4 (en) SOLID ACID CATALYST, PRODUCTION PROCESS AND METHOD FOR PRODUCING A FATTY ACID ELECTROLYMER THEREWITH
CL2012003665A1 (es) Molecula de acido nucleico aislada que codifica una enzima delta-9-desaturasa; polipeptido de delta-9-desaturasa quimerica; metodo para disminuir la cantidad de acidos grasos saturados en una celula.
EP2851361A4 (en) HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYLENE WITH REDUCED ENVIRONMENTAL CHARACTERISTICS AND METHOD FOR THE PRODUCTION THEREOF
BR112012001125A2 (pt) Novo a9 elongase para a produção de óleos enriquecidos com ácido graxo polinsaturados.
BRPI1010614A2 (pt) polinucleotídeo, vetor, célula hospedeira, métodos para a fabricação de um polipeptídeo, de ácidos graxos poliinsaturados, e de um óleo, lipídeo ou composição de ácido graxo, polipeptídeo, organismo trangênico não humano, e, óleo.
EP3208261A4 (en) Method for preparing glyceride type polyunsaturated fatty acids
BR112013008191A2 (pt) método para produzir ésteres de ácido metacrílico
BR112013033537A2 (pt) processo para a síntese de ácidos omega-funcionalizados a partir de ácidos graxos ou ésteres
ZA201400886B (en) Method for synthesizing an omega-amino acid or ester from a monousaturated fatty acid or ester
BRPI1011100A2 (pt) Emulsão ou gel para a produção de alimentos contendo ácido graxo ômega-3.
HK1223126A1 (zh) 不飽和脂肪酸酶和二十碳五烯酸的製備方法
EP3073817A4 (en) Production of omega-3 long-chain polyunsaturated fatty acids in oilseed crops by a thraustochytrid pufa synthase
EP3109315A4 (en) Method for the enrichment of microalgae biomass in polyunsaturated fatty acids
IL229617A0 (en) Healthy foodstuffs containing ethyl esters of fatty acids, especially of flax oil, and a method for their production
CL2013000507A1 (es) Polinucleotido aislado que codifica una delta-9 elongasa; constructo recombinante, celual transformada; metodo para producir acido graso poliinsaturado; aceite microbiano.