CN113038933A - 含布洛芬经口药物制剂 - Google Patents
含布洛芬经口药物制剂 Download PDFInfo
- Publication number
- CN113038933A CN113038933A CN201980075319.1A CN201980075319A CN113038933A CN 113038933 A CN113038933 A CN 113038933A CN 201980075319 A CN201980075319 A CN 201980075319A CN 113038933 A CN113038933 A CN 113038933A
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- China
- Prior art keywords
- ibuprofen
- component
- oral pharmaceutical
- oral
- weight ratio
- Prior art date
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- 239000006190 sub-lingual tablet Substances 0.000 description 1
- 229960004291 sucralfate Drugs 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 150000003544 thiamines Chemical class 0.000 description 1
- 229960003737 timepidium bromide Drugs 0.000 description 1
- JWIXXNLOKOAAQT-UHFFFAOYSA-N tipepidine Chemical compound C1N(C)CCCC1=C(C=1SC=CC=1)C1=CC=CS1 JWIXXNLOKOAAQT-UHFFFAOYSA-N 0.000 description 1
- 229960000896 tipepidine Drugs 0.000 description 1
- 229960002388 tizanidine hydrochloride Drugs 0.000 description 1
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 1
- 229960000401 tranexamic acid Drugs 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 150000003700 vitamin C derivatives Chemical class 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 239000001841 zingiber officinale Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018215891 | 2018-11-16 | ||
| JP2018-215891 | 2018-11-16 | ||
| PCT/JP2019/044835 WO2020101012A1 (en) | 2018-11-16 | 2019-11-15 | Ibuprofen-containing oral pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113038933A true CN113038933A (zh) | 2021-06-25 |
Family
ID=68733560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980075319.1A Pending CN113038933A (zh) | 2018-11-16 | 2019-11-15 | 含布洛芬经口药物制剂 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210369618A1 (ja) |
| EP (1) | EP3880171B1 (ja) |
| JP (1) | JP7406349B2 (ja) |
| KR (1) | KR20210092202A (ja) |
| CN (1) | CN113038933A (ja) |
| AU (1) | AU2019380973A1 (ja) |
| BR (1) | BR112021009468A2 (ja) |
| HU (1) | HUE062682T2 (ja) |
| MX (1) | MX2021005765A (ja) |
| PL (1) | PL3880171T3 (ja) |
| WO (1) | WO2020101012A1 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230116831A (ko) * | 2020-11-30 | 2023-08-04 | 에스에스 세야쿠 가부시키 가이샤 | 이부프로펜을 함유하는 고형 제제 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0264187A1 (en) * | 1986-10-01 | 1988-04-20 | The Boots Company PLC | Pharmaceutical composition containing ibuprofen and aluminium hydroxide |
| CN1083728A (zh) * | 1992-07-30 | 1994-03-16 | 美国辉瑞有限公司 | 苦味药剂的掩盖了味道的组合物 |
| JPH08337524A (ja) * | 1995-06-15 | 1996-12-24 | Taisho Pharmaceut Co Ltd | イブプロフェン懸濁液剤 |
| JP2007023026A (ja) * | 2005-06-17 | 2007-02-01 | Daiichi Sankyo Healthcare Co Ltd | イブプロフェン含有経口用医薬組成物 |
| CN101134013A (zh) * | 2006-08-30 | 2008-03-05 | Ss制药株式会社 | 口服用制剂 |
| CN103156812A (zh) * | 2011-12-08 | 2013-06-19 | 杭州赛利药物研究所有限公司 | 右旋布洛芬干混悬剂及其制备方法 |
| JP2017043546A (ja) * | 2015-08-24 | 2017-03-02 | エスエス製薬株式会社 | 感冒用医薬組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3159723B2 (ja) * | 1991-03-22 | 2001-04-23 | 武田薬品工業株式会社 | 非晶質組成物およびその製造方法 |
| JP2001031562A (ja) | 1999-07-16 | 2001-02-06 | Taisho Pharmaceut Co Ltd | 内服液剤 |
| WO2010117035A1 (ja) * | 2009-04-09 | 2010-10-14 | ライオン株式会社 | 複合体及びその製造方法、ならびに粒状剤及び錠剤 |
| JP6822034B2 (ja) * | 2015-09-29 | 2021-01-27 | 大正製薬株式会社 | 安定性及び速効性の高いイブプロフェン含有固形製剤 |
| JP6877923B2 (ja) * | 2016-09-06 | 2021-05-26 | ライオン株式会社 | 内服用半固形製剤及びその製造方法 |
-
2019
- 2019-11-15 WO PCT/JP2019/044835 patent/WO2020101012A1/en active Application Filing
- 2019-11-15 CN CN201980075319.1A patent/CN113038933A/zh active Pending
- 2019-11-15 JP JP2019206693A patent/JP7406349B2/ja active Active
- 2019-11-15 HU HUE19813181A patent/HUE062682T2/hu unknown
- 2019-11-15 KR KR1020217013071A patent/KR20210092202A/ko active Search and Examination
- 2019-11-15 US US17/290,915 patent/US20210369618A1/en active Pending
- 2019-11-15 BR BR112021009468-7A patent/BR112021009468A2/pt unknown
- 2019-11-15 AU AU2019380973A patent/AU2019380973A1/en active Pending
- 2019-11-15 PL PL19813181.5T patent/PL3880171T3/pl unknown
- 2019-11-15 EP EP19813181.5A patent/EP3880171B1/en active Active
- 2019-11-15 MX MX2021005765A patent/MX2021005765A/es unknown
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0264187A1 (en) * | 1986-10-01 | 1988-04-20 | The Boots Company PLC | Pharmaceutical composition containing ibuprofen and aluminium hydroxide |
| CN1083728A (zh) * | 1992-07-30 | 1994-03-16 | 美国辉瑞有限公司 | 苦味药剂的掩盖了味道的组合物 |
| JPH08337524A (ja) * | 1995-06-15 | 1996-12-24 | Taisho Pharmaceut Co Ltd | イブプロフェン懸濁液剤 |
| JP2007023026A (ja) * | 2005-06-17 | 2007-02-01 | Daiichi Sankyo Healthcare Co Ltd | イブプロフェン含有経口用医薬組成物 |
| CN101134013A (zh) * | 2006-08-30 | 2008-03-05 | Ss制药株式会社 | 口服用制剂 |
| CN103156812A (zh) * | 2011-12-08 | 2013-06-19 | 杭州赛利药物研究所有限公司 | 右旋布洛芬干混悬剂及其制备方法 |
| JP2017043546A (ja) * | 2015-08-24 | 2017-03-02 | エスエス製薬株式会社 | 感冒用医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3880171C0 (en) | 2023-06-07 |
| EP3880171A1 (en) | 2021-09-22 |
| JP2020083884A (ja) | 2020-06-04 |
| JP7406349B2 (ja) | 2023-12-27 |
| MX2021005765A (es) | 2021-08-11 |
| US20210369618A1 (en) | 2021-12-02 |
| EP3880171B1 (en) | 2023-06-07 |
| HUE062682T2 (hu) | 2023-11-28 |
| AU2019380973A1 (en) | 2021-05-13 |
| WO2020101012A1 (en) | 2020-05-22 |
| PL3880171T3 (pl) | 2024-02-19 |
| KR20210092202A (ko) | 2021-07-23 |
| BR112021009468A2 (pt) | 2021-08-10 |
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