CN1129938A - 作用于AMPA受体的烷氧基取代的β-咔啉 - Google Patents

作用于AMPA受体的烷氧基取代的β-咔啉 Download PDF

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Publication number
CN1129938A
CN1129938A CN94193211A CN94193211A CN1129938A CN 1129938 A CN1129938 A CN 1129938A CN 94193211 A CN94193211 A CN 94193211A CN 94193211 A CN94193211 A CN 94193211A CN 1129938 A CN1129938 A CN 1129938A
Authority
CN
China
Prior art keywords
alkyl
compound
formula
lin
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94193211A
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English (en)
Chinese (zh)
Inventor
D·塞德曼
L·特斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of CN1129938A publication Critical patent/CN1129938A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN94193211A 1993-08-31 1994-08-29 作用于AMPA受体的烷氧基取代的β-咔啉 Pending CN1129938A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4330175.4 1993-08-31
DE4330175A DE4330175A1 (de) 1993-08-31 1993-08-31 Alkoxy-substituierte beta-Carboline

Publications (1)

Publication Number Publication Date
CN1129938A true CN1129938A (zh) 1996-08-28

Family

ID=6497015

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94193211A Pending CN1129938A (zh) 1993-08-31 1994-08-29 作用于AMPA受体的烷氧基取代的β-咔啉

Country Status (17)

Country Link
EP (1) EP0716657A1 (de)
JP (1) JPH09501938A (de)
KR (1) KR960704888A (de)
CN (1) CN1129938A (de)
AU (1) AU7530394A (de)
CA (1) CA2170615A1 (de)
CZ (1) CZ50596A3 (de)
DE (1) DE4330175A1 (de)
FI (1) FI960940A (de)
HU (1) HUT73845A (de)
IL (1) IL110745A0 (de)
NO (1) NO960812D0 (de)
NZ (1) NZ271615A (de)
PL (1) PL313230A1 (de)
SK (1) SK23896A3 (de)
WO (1) WO1995006647A1 (de)
ZA (1) ZA946670B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125942A (en) 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
EP4092013A1 (de) 2017-06-20 2022-11-23 Imbria Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur erhöhung der effizienz des herzmetabolismus
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
IL87563A (en) * 1987-08-28 1993-08-18 Schering Ag Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE3943225A1 (de) * 1989-12-23 1991-06-27 Schering Ag Neue ss-carboline, verfahren zu deren herstellung und deren verwendung in arzneimitteln
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4120109A1 (de) * 1991-06-15 1992-12-17 Schering Ag 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4130933A1 (de) * 1991-09-13 1993-03-18 Schering Ag Neue (beta)-carbolinderivate, deren herstellung und verwendung in arzneimitteln
DE4212529A1 (de) * 1992-04-10 1993-10-14 Schering Ag Verwendung von µ-Carbolinen als nicht-kompetitive Glutamat-Antagonisten

Also Published As

Publication number Publication date
NO960812L (no) 1996-02-28
CA2170615A1 (en) 1995-03-09
NO960812D0 (no) 1996-02-28
NZ271615A (en) 1996-09-25
AU7530394A (en) 1995-03-22
ZA946670B (en) 1995-04-21
FI960940A0 (fi) 1996-02-28
HUT73845A (en) 1996-09-30
HU9600505D0 (en) 1996-04-29
PL313230A1 (en) 1996-06-10
DE4330175A1 (de) 1995-03-02
CZ50596A3 (en) 1996-06-12
IL110745A0 (en) 1994-11-11
FI960940A (fi) 1996-02-28
WO1995006647A1 (de) 1995-03-09
JPH09501938A (ja) 1997-02-25
EP0716657A1 (de) 1996-06-19
KR960704888A (ko) 1996-10-09
SK23896A3 (en) 1996-11-06

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PB01 Publication
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C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication