HUT73845A - Alkoxy-substituted beta-carbolines acting on the ampa-receptor, process for producing them and pharmaceutical compositions - Google Patents

Alkoxy-substituted beta-carbolines acting on the ampa-receptor, process for producing them and pharmaceutical compositions Download PDF

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Publication number
HUT73845A
HUT73845A HU9600505A HU9600505A HUT73845A HU T73845 A HUT73845 A HU T73845A HU 9600505 A HU9600505 A HU 9600505A HU 9600505 A HU9600505 A HU 9600505A HU T73845 A HUT73845 A HU T73845A
Authority
HU
Hungary
Prior art keywords
alkyl
formula
alkoxy
carboline
phenyl
Prior art date
Application number
HU9600505A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9600505D0 (en
Inventor
Dieter Seidelmann
Lechoslaw Turski
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of HU9600505D0 publication Critical patent/HU9600505D0/hu
Publication of HUT73845A publication Critical patent/HUT73845A/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU9600505A 1993-08-31 1994-08-29 Alkoxy-substituted beta-carbolines acting on the ampa-receptor, process for producing them and pharmaceutical compositions HUT73845A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4330175A DE4330175A1 (de) 1993-08-31 1993-08-31 Alkoxy-substituierte beta-Carboline

Publications (2)

Publication Number Publication Date
HU9600505D0 HU9600505D0 (en) 1996-04-29
HUT73845A true HUT73845A (en) 1996-09-30

Family

ID=6497015

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9600505A HUT73845A (en) 1993-08-31 1994-08-29 Alkoxy-substituted beta-carbolines acting on the ampa-receptor, process for producing them and pharmaceutical compositions

Country Status (17)

Country Link
EP (1) EP0716657A1 (de)
JP (1) JPH09501938A (de)
KR (1) KR960704888A (de)
CN (1) CN1129938A (de)
AU (1) AU7530394A (de)
CA (1) CA2170615A1 (de)
CZ (1) CZ50596A3 (de)
DE (1) DE4330175A1 (de)
FI (1) FI960940A (de)
HU (1) HUT73845A (de)
IL (1) IL110745A0 (de)
NO (1) NO960812D0 (de)
NZ (1) NZ271615A (de)
PL (1) PL313230A1 (de)
SK (1) SK23896A3 (de)
WO (1) WO1995006647A1 (de)
ZA (1) ZA946670B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125942A (en) 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
JP2020527133A (ja) 2017-06-20 2020-09-03 インブリア ファーマシューティカルズ, インコーポレイテッド 心臓代謝の効率を高めるための組成物および方法
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
AU619203B2 (en) * 1987-08-28 1992-01-23 Schering Aktiengesellschaft Isoxazole-beta-carboline derivatives
DE3943225A1 (de) * 1989-12-23 1991-06-27 Schering Ag Neue ss-carboline, verfahren zu deren herstellung und deren verwendung in arzneimitteln
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4120109A1 (de) * 1991-06-15 1992-12-17 Schering Ag 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4130933A1 (de) * 1991-09-13 1993-03-18 Schering Ag Neue (beta)-carbolinderivate, deren herstellung und verwendung in arzneimitteln
DE4212529A1 (de) * 1992-04-10 1993-10-14 Schering Ag Verwendung von µ-Carbolinen als nicht-kompetitive Glutamat-Antagonisten

Also Published As

Publication number Publication date
JPH09501938A (ja) 1997-02-25
WO1995006647A1 (de) 1995-03-09
IL110745A0 (en) 1994-11-11
KR960704888A (ko) 1996-10-09
CN1129938A (zh) 1996-08-28
PL313230A1 (en) 1996-06-10
NZ271615A (en) 1996-09-25
AU7530394A (en) 1995-03-22
EP0716657A1 (de) 1996-06-19
CA2170615A1 (en) 1995-03-09
SK23896A3 (en) 1996-11-06
FI960940A0 (fi) 1996-02-28
NO960812L (no) 1996-02-28
ZA946670B (en) 1995-04-21
NO960812D0 (no) 1996-02-28
HU9600505D0 (en) 1996-04-29
DE4330175A1 (de) 1995-03-02
CZ50596A3 (en) 1996-06-12
FI960940A (fi) 1996-02-28

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Legal Events

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DFC4 Cancellation of temporary protection due to refusal