KR960704888A - AMPA-수용체에 작용하는 알콕시-치환 β-카르보린 (Alkoxy-Substituted β-Carbolines Acting on The AMPA-Receptor) - Google Patents

AMPA-수용체에 작용하는 알콕시-치환 β-카르보린 (Alkoxy-Substituted β-Carbolines Acting on The AMPA-Receptor)

Info

Publication number
KR960704888A
KR960704888A KR1019960701006A KR19960701006A KR960704888A KR 960704888 A KR960704888 A KR 960704888A KR 1019960701006 A KR1019960701006 A KR 1019960701006A KR 19960701006 A KR19960701006 A KR 19960701006A KR 960704888 A KR960704888 A KR 960704888A
Authority
KR
South Korea
Prior art keywords
alkyl
compound
formula
alkoxy
phenyl
Prior art date
Application number
KR1019960701006A
Other languages
English (en)
Korean (ko)
Inventor
디에터 쉐델만
레코스로우 투르스키
Original Assignee
클로제, 키르쉬
쉐링 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 클로제, 키르쉬, 쉐링 악티엔게젤샤프트 filed Critical 클로제, 키르쉬
Publication of KR960704888A publication Critical patent/KR960704888A/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019960701006A 1993-08-31 1994-08-29 AMPA-수용체에 작용하는 알콕시-치환 β-카르보린 (Alkoxy-Substituted β-Carbolines Acting on The AMPA-Receptor) KR960704888A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4330175.4 1993-08-31
DE4330175A DE4330175A1 (de) 1993-08-31 1993-08-31 Alkoxy-substituierte beta-Carboline
PCT/DE1994/001009 WO1995006647A1 (de) 1993-08-31 1994-08-29 ALKOXY-SUBSTITUIERTE β-CARBOLINE MIT EINWIRKUNG AUF DEN AMPA-REZEPTOR

Publications (1)

Publication Number Publication Date
KR960704888A true KR960704888A (ko) 1996-10-09

Family

ID=6497015

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960701006A KR960704888A (ko) 1993-08-31 1994-08-29 AMPA-수용체에 작용하는 알콕시-치환 β-카르보린 (Alkoxy-Substituted β-Carbolines Acting on The AMPA-Receptor)

Country Status (17)

Country Link
EP (1) EP0716657A1 (de)
JP (1) JPH09501938A (de)
KR (1) KR960704888A (de)
CN (1) CN1129938A (de)
AU (1) AU7530394A (de)
CA (1) CA2170615A1 (de)
CZ (1) CZ50596A3 (de)
DE (1) DE4330175A1 (de)
FI (1) FI960940A (de)
HU (1) HUT73845A (de)
IL (1) IL110745A0 (de)
NO (1) NO960812D0 (de)
NZ (1) NZ271615A (de)
PL (1) PL313230A1 (de)
SK (1) SK23896A3 (de)
WO (1) WO1995006647A1 (de)
ZA (1) ZA946670B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125942A (en) 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
EP4092013A1 (de) 2017-06-20 2022-11-23 Imbria Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur erhöhung der effizienz des herzmetabolismus
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
IL87563A (en) * 1987-08-28 1993-08-18 Schering Ag Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE3943225A1 (de) * 1989-12-23 1991-06-27 Schering Ag Neue ss-carboline, verfahren zu deren herstellung und deren verwendung in arzneimitteln
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4120109A1 (de) * 1991-06-15 1992-12-17 Schering Ag 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4130933A1 (de) * 1991-09-13 1993-03-18 Schering Ag Neue (beta)-carbolinderivate, deren herstellung und verwendung in arzneimitteln
DE4212529A1 (de) * 1992-04-10 1993-10-14 Schering Ag Verwendung von µ-Carbolinen als nicht-kompetitive Glutamat-Antagonisten

Also Published As

Publication number Publication date
NO960812L (no) 1996-02-28
CA2170615A1 (en) 1995-03-09
NO960812D0 (no) 1996-02-28
NZ271615A (en) 1996-09-25
AU7530394A (en) 1995-03-22
ZA946670B (en) 1995-04-21
FI960940A0 (fi) 1996-02-28
HUT73845A (en) 1996-09-30
HU9600505D0 (en) 1996-04-29
CN1129938A (zh) 1996-08-28
PL313230A1 (en) 1996-06-10
DE4330175A1 (de) 1995-03-02
CZ50596A3 (en) 1996-06-12
IL110745A0 (en) 1994-11-11
FI960940A (fi) 1996-02-28
WO1995006647A1 (de) 1995-03-09
JPH09501938A (ja) 1997-02-25
EP0716657A1 (de) 1996-06-19
SK23896A3 (en) 1996-11-06

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