ATE25519T1 - Benzo(f)chinolinderivate. - Google Patents
Benzo(f)chinolinderivate.Info
- Publication number
- ATE25519T1 ATE25519T1 AT83111157T AT83111157T ATE25519T1 AT E25519 T1 ATE25519 T1 AT E25519T1 AT 83111157 T AT83111157 T AT 83111157T AT 83111157 T AT83111157 T AT 83111157T AT E25519 T1 ATE25519 T1 AT E25519T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- hydrogen
- benzo
- quinoline derivatives
- hydroxy
- Prior art date
Links
- HCAUQPZEWLULFJ-UHFFFAOYSA-N benzo[f]quinoline Chemical class C1=CC=C2C3=CC=CC=C3C=CC2=N1 HCAUQPZEWLULFJ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP1982/000438 WO1984001948A1 (fr) | 1982-11-10 | 1982-11-10 | DERIVES DE BENZO ADf BD QUINOLINE |
| EP83111157A EP0109039B1 (de) | 1982-11-10 | 1983-11-08 | Benzo(f)chinolinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE25519T1 true ATE25519T1 (de) | 1987-03-15 |
Family
ID=13762362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83111157T ATE25519T1 (de) | 1982-11-10 | 1983-11-08 | Benzo(f)chinolinderivate. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4543354A (de) |
| EP (1) | EP0109039B1 (de) |
| JP (1) | JPS5993055A (de) |
| AT (1) | ATE25519T1 (de) |
| DE (1) | DE3369843D1 (de) |
| ES (1) | ES527115A0 (de) |
| WO (1) | WO1984001948A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3707773C2 (de) * | 1987-03-11 | 1996-09-05 | Bbc Brown Boveri & Cie | Einrichtung zur Prozesswärmeerzeugung |
| JPH05505599A (ja) * | 1990-03-15 | 1993-08-19 | ジ・アップジョン・カンパニー | 治療上有用な複素環インドール化合物類 |
| US5863928A (en) | 1993-11-19 | 1999-01-26 | The Board Of Governors For Higher Education The State Of Rhode Island And Providence Plantation. | Octahydrobenzo f!quinoline-based receptor agonists and antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3043842A (en) * | 1959-02-09 | 1962-07-10 | Smith Kline French Lab | Substituted acridans |
| JPS5782371A (en) * | 1980-11-11 | 1982-05-22 | Yoshitomi Pharmaceut Ind Ltd | Benzoquinoline derivative and its preparation |
| US4341786A (en) * | 1981-03-02 | 1982-07-27 | Smithkline Corporation | Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds |
-
1982
- 1982-11-10 WO PCT/JP1982/000438 patent/WO1984001948A1/ja not_active Ceased
-
1983
- 1983-10-28 JP JP58203569A patent/JPS5993055A/ja active Granted
- 1983-11-08 EP EP83111157A patent/EP0109039B1/de not_active Expired
- 1983-11-08 AT AT83111157T patent/ATE25519T1/de not_active IP Right Cessation
- 1983-11-08 ES ES527115A patent/ES527115A0/es active Granted
- 1983-11-08 DE DE8383111157T patent/DE3369843D1/de not_active Expired
- 1983-11-10 US US06/550,423 patent/US4543354A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES8504715A1 (es) | 1985-05-01 |
| WO1984001948A1 (fr) | 1984-05-24 |
| EP0109039A1 (de) | 1984-05-23 |
| EP0109039B1 (de) | 1987-02-25 |
| ES527115A0 (es) | 1985-05-01 |
| JPS5993055A (ja) | 1984-05-29 |
| JPH0114913B2 (de) | 1989-03-14 |
| DE3369843D1 (en) | 1987-04-02 |
| US4543354A (en) | 1985-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |