ATE25519T1 - Benzo(f)chinolinderivate. - Google Patents

Benzo(f)chinolinderivate.

Info

Publication number
ATE25519T1
ATE25519T1 AT83111157T AT83111157T ATE25519T1 AT E25519 T1 ATE25519 T1 AT E25519T1 AT 83111157 T AT83111157 T AT 83111157T AT 83111157 T AT83111157 T AT 83111157T AT E25519 T1 ATE25519 T1 AT E25519T1
Authority
AT
Austria
Prior art keywords
alkyl
hydrogen
benzo
quinoline derivatives
hydroxy
Prior art date
Application number
AT83111157T
Other languages
English (en)
Inventor
Toru Nakao
Tsuguo Ikebe
Tetsuya Tahara
Yutaka Maruyama
Osamu Yaoka
Original Assignee
Yoshitomi Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical filed Critical Yoshitomi Pharmaceutical
Application granted granted Critical
Publication of ATE25519T1 publication Critical patent/ATE25519T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT83111157T 1982-11-10 1983-11-08 Benzo(f)chinolinderivate. ATE25519T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/JP1982/000438 WO1984001948A1 (en) 1982-11-10 1982-11-10 BENZO ADf BD QUINOLINE DERIVATIVES
EP83111157A EP0109039B1 (de) 1982-11-10 1983-11-08 Benzo(f)chinolinderivate

Publications (1)

Publication Number Publication Date
ATE25519T1 true ATE25519T1 (de) 1987-03-15

Family

ID=13762362

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83111157T ATE25519T1 (de) 1982-11-10 1983-11-08 Benzo(f)chinolinderivate.

Country Status (7)

Country Link
US (1) US4543354A (de)
EP (1) EP0109039B1 (de)
JP (1) JPS5993055A (de)
AT (1) ATE25519T1 (de)
DE (1) DE3369843D1 (de)
ES (1) ES527115A0 (de)
WO (1) WO1984001948A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707773C2 (de) * 1987-03-11 1996-09-05 Bbc Brown Boveri & Cie Einrichtung zur Prozesswärmeerzeugung
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
US5863928A (en) 1993-11-19 1999-01-26 The Board Of Governors For Higher Education The State Of Rhode Island And Providence Plantation. Octahydrobenzo f!quinoline-based receptor agonists and antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3043842A (en) * 1959-02-09 1962-07-10 Smith Kline French Lab Substituted acridans
JPS5782371A (en) * 1980-11-11 1982-05-22 Yoshitomi Pharmaceut Ind Ltd Benzoquinoline derivative and its preparation
US4341786A (en) * 1981-03-02 1982-07-27 Smithkline Corporation Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds

Also Published As

Publication number Publication date
JPH0114913B2 (de) 1989-03-14
WO1984001948A1 (en) 1984-05-24
EP0109039A1 (de) 1984-05-23
EP0109039B1 (de) 1987-02-25
DE3369843D1 (en) 1987-04-02
ES8504715A1 (es) 1985-05-01
US4543354A (en) 1985-09-24
JPS5993055A (ja) 1984-05-29
ES527115A0 (es) 1985-05-01

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties