CN110545799A - 用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途 - Google Patents

用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途 Download PDF

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CN110545799A
CN110545799A CN201980001842.XA CN201980001842A CN110545799A CN 110545799 A CN110545799 A CN 110545799A CN 201980001842 A CN201980001842 A CN 201980001842A CN 110545799 A CN110545799 A CN 110545799A
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vulnerable plaque
delivery system
plaque
vulnerable
atherosclerosis
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CN110545799B (zh
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马茜
孙洁芳
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Beijing Inno Medicine Co ltd
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Abstract

一种用于靶向活化的CD44分子的重组仿生纳米载体递送系统，所述纳米载体的表面部分地被靶向配体修饰，所述靶向配体是能与活化的CD44分子特异性结合的配体。一种重组仿生纳米载体递送系统的制备方法和用途。该重组仿生纳米载体递送系统可用于易损斑块或与易损斑块相关的疾病的诊断、预防和治疗。

Description

PCT国内申请，说明书已公开。

Claims (20)

  1. PCT国内申请，权利要求书已公开。
CN201980001842.XA 2018-01-22 2019-01-21 用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途 Active CN110545799B (zh)

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CN2018100602659 2018-01-22
CN201810060265 2018-01-22
PCT/CN2019/072477 WO2019141267A1 (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途

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CN110545799B CN110545799B (zh) 2021-02-26

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CN201980001842.XA Active CN110545799B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途
CN201980001837.9A Active CN110545795B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的水凝胶纳米载体递送系统、其制备方法和用途
CN201980001820.3A Active CN110545794B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的胶束纳米载体递送系统、其制备方法和用途
CN201980001841.5A Active CN110536680B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的树枝状聚合物纳米载体递送系统、其制备方法和用途
CN201980001845.3A Active CN110545793B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的金属框架化合物纳米载体递送系统、其制备方法和用途
CN201980001833.0A Active CN110573144B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途
CN201980001846.8A Active CN110545800B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的纳米钙载体递送系统、其制备方法和用途
CN201980001832.6A Active CN110573145B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的介孔/中空二氧化硅纳米载体递送系统、其制备方法和用途
CN201980001843.4A Active CN110545798B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的脂质体纳米载体递送系统、其制备方法和用途

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CN201980001820.3A Active CN110545794B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的胶束纳米载体递送系统、其制备方法和用途
CN201980001841.5A Active CN110536680B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的树枝状聚合物纳米载体递送系统、其制备方法和用途
CN201980001845.3A Active CN110545793B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的金属框架化合物纳米载体递送系统、其制备方法和用途
CN201980001833.0A Active CN110573144B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途
CN201980001846.8A Active CN110545800B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的纳米钙载体递送系统、其制备方法和用途
CN201980001832.6A Active CN110573145B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的介孔/中空二氧化硅纳米载体递送系统、其制备方法和用途
CN201980001843.4A Active CN110545798B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的脂质体纳米载体递送系统、其制备方法和用途

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US (2) US20200397926A1 (zh)
EP (1) EP3744317A4 (zh)
JP (2) JP7436367B2 (zh)
KR (1) KR20200111185A (zh)
CN (9) CN110545799B (zh)
AU (1) AU2019208796A1 (zh)
CA (1) CA3087606A1 (zh)
WO (9) WO2019141278A1 (zh)

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CN111569053A (zh) * 2020-03-13 2020-08-25 中国科学院长春应用化学研究所 一种通过调控肿瘤代谢行为增强免疫治疗的纳米酶及其制备方法与应用
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CN111821470B (zh) * 2020-09-01 2022-08-12 中南大学 包载甲氨蝶呤的铁-鞣酸配合物及其制备方法与应用
CN112426533A (zh) * 2020-12-01 2021-03-02 南通大学附属医院 一种纳米碳酸钙载药系统、其制备方法及其应用
CN114276563B (zh) * 2020-12-14 2023-02-24 南京工业大学 医用水凝胶的制备方法、水凝胶及敷料
CN114788871B (zh) * 2021-01-25 2024-02-06 山东大学 寡聚芦丁在制备肿瘤靶向产品中的应用及寡聚芦丁-硼替佐米肿瘤靶向递药系统
CN113244172B (zh) * 2021-03-29 2023-05-23 中山大学附属第一医院 一种siRNA和抗癌药靶向共递送系统及其制备方法和应用
CN113577300B (zh) * 2021-06-29 2022-01-25 首都医科大学附属北京儿童医院 一种靶向脂质体药物递送系统及其制备方法和应用
CN113402684B (zh) * 2021-07-02 2022-02-18 肇庆医学高等专科学校 一种磁性表面印迹材料的制备方法及其在识别与拆分氨氯地平中的应用
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