CN110573144A - 用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途 - Google Patents

用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途 Download PDF

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CN110573144A
CN110573144A CN201980001833.0A CN201980001833A CN110573144A CN 110573144 A CN110573144 A CN 110573144A CN 201980001833 A CN201980001833 A CN 201980001833A CN 110573144 A CN110573144 A CN 110573144A
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silica
vulnerable plaque
delivery system
plaque
vulnerable
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CN110573144B (zh
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马茜
孙洁芳
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Beijing Inno Medicine Co ltd
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Abstract

一种用于靶向活化的CD44分子的硅质体纳米载体递送系统及其制备方法，所述纳米载体的表面部分地被靶向配体修饰，所述靶向配体是能与活化的CD44分子特异性结合的配体。该硅质体纳米载体递送系统在制备用于诊断、预防和治疗易损斑块或与易损斑块相关疾病的药物中的用途。

Description

PCT国内申请，说明书已公开。

Claims (20)

  1. PCT国内申请，权利要求书已公开。
CN201980001833.0A 2018-01-22 2019-01-21 用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途 Active CN110573144B (zh)

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CN201810060265 2018-01-22
CN2018100602659 2018-01-22
PCT/CN2019/072559 WO2019141275A1 (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途

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CN110573144B CN110573144B (zh) 2021-02-26

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CN201980001845.3A Active CN110545793B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的金属框架化合物纳米载体递送系统、其制备方法和用途
CN201980001842.XA Active CN110545799B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途
CN201980001843.4A Active CN110545798B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的脂质体纳米载体递送系统、其制备方法和用途
CN201980001846.8A Active CN110545800B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的纳米钙载体递送系统、其制备方法和用途
CN201980001841.5A Active CN110536680B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的树枝状聚合物纳米载体递送系统、其制备方法和用途
CN201980001820.3A Active CN110545794B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的胶束纳米载体递送系统、其制备方法和用途
CN201980001833.0A Active CN110573144B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的硅质体纳米载体递送系统、其制备方法和用途
CN201980001837.9A Active CN110545795B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的水凝胶纳米载体递送系统、其制备方法和用途
CN201980001832.6A Active CN110573145B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的介孔/中空二氧化硅纳米载体递送系统、其制备方法和用途

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CN201980001842.XA Active CN110545799B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的重组仿生纳米载体递送系统、其制备方法和用途
CN201980001843.4A Active CN110545798B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的脂质体纳米载体递送系统、其制备方法和用途
CN201980001846.8A Active CN110545800B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的纳米钙载体递送系统、其制备方法和用途
CN201980001841.5A Active CN110536680B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的树枝状聚合物纳米载体递送系统、其制备方法和用途
CN201980001820.3A Active CN110545794B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的胶束纳米载体递送系统、其制备方法和用途

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CN201980001832.6A Active CN110573145B (zh) 2018-01-22 2019-01-21 用于靶向活化cd44分子的介孔/中空二氧化硅纳米载体递送系统、其制备方法和用途

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US (2) US20200397926A1 (zh)
EP (1) EP3744317A4 (zh)
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KR (1) KR20200111185A (zh)
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AU (1) AU2019208796B2 (zh)
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CN111701032A (zh) * 2020-06-23 2020-09-25 重庆大学附属肿瘤医院 兼具药物控释及成像功能的介孔氧化硅复合体的制备方法
CN112076158B (zh) * 2020-08-28 2023-12-08 西南民族大学 一种治疗慢性肾炎的脂质体-纳米粒复合体
CN111821470B (zh) * 2020-09-01 2022-08-12 中南大学 包载甲氨蝶呤的铁-鞣酸配合物及其制备方法与应用
CN112426533A (zh) * 2020-12-01 2021-03-02 南通大学附属医院 一种纳米碳酸钙载药系统、其制备方法及其应用
CN114276563B (zh) * 2020-12-14 2023-02-24 南京工业大学 医用水凝胶的制备方法、水凝胶及敷料
CN114788871B (zh) * 2021-01-25 2024-02-06 山东大学 寡聚芦丁在制备肿瘤靶向产品中的应用及寡聚芦丁-硼替佐米肿瘤靶向递药系统
CN113244172B (zh) * 2021-03-29 2023-05-23 中山大学附属第一医院 一种siRNA和抗癌药靶向共递送系统及其制备方法和应用
CN113577300B (zh) * 2021-06-29 2022-01-25 首都医科大学附属北京儿童医院 一种靶向脂质体药物递送系统及其制备方法和应用
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