CN109477993B - β-羟基丁酸酯和丁二醇的中链脂肪酸酯和组合物及其使用方法 - Google Patents

β-羟基丁酸酯和丁二醇的中链脂肪酸酯和组合物及其使用方法 Download PDF

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CN109477993B
CN109477993B CN201780041428.2A CN201780041428A CN109477993B CN 109477993 B CN109477993 B CN 109477993B CN 201780041428 A CN201780041428 A CN 201780041428A CN 109477993 B CN109477993 B CN 109477993B
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mice
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CN109477993A (zh
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E·维丁
S·乌尔里希
J·纽曼
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J David Gladstone Institutes
University of California San Diego UCSD
Ithaca College
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University of California San Diego UCSD
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CN201780041428.2A 2016-06-07 2017-06-02 β-羟基丁酸酯和丁二醇的中链脂肪酸酯和组合物及其使用方法 Active CN109477993B (zh)

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US201662346975P 2016-06-07 2016-06-07
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PCT/US2017/035826 WO2017213999A1 (en) 2016-06-07 2017-06-02 Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same

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RU2761829C2 (ru) 2016-06-07 2021-12-13 Зе Дж. Дэвид Глэдстоун Инститьютс Образуемые среднецепочечными жирными кислотами сложные эфиры бета-гидроксибутирата и бутандиола и композиции и способы на их основе
WO2019018683A1 (en) 2017-07-21 2019-01-24 Buck Institute For Research On Aging BETA-HYDROXYBUTYRATE AND BUTANEDIOL ENANTIOMERS AND METHODS OF USE THEREOF
US12037317B2 (en) 2018-01-25 2024-07-16 Buck Institute For Research On Aging Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
US20190248733A1 (en) * 2018-02-14 2019-08-15 Benjamin Bikman Oral supplements of fatty acid and amino acid ketone esters to improve metabolic, physical and cognitive health
WO2020147981A1 (de) * 2019-01-17 2020-07-23 Ioi Oleo Gmbh Verfahren zur herstellung von verkappten 3-hydroxycarbonsäuren sowie deren salzen und estern
EP3880642A1 (de) * 2019-01-17 2021-09-22 IOI Oleo GmbH Verfahren zur herstellung von fettalkoholestern von hydroxycarbonsäuren
CN113574048B (zh) * 2019-01-17 2024-06-18 凯托利皮克斯治疗有限责任公司 生产任选的酰化羟基羧酸的多元醇基酯的方法
CN110372502A (zh) * 2019-07-25 2019-10-25 润泰化学（泰兴）有限公司 一种1,3-二醇的双酯化合成方法
GB201918657D0 (en) 2019-12-17 2020-01-29 Tdeltas Ltd Compounds for new use
CN116113617A (zh) * 2020-07-13 2023-05-12 Ioi油脂化学品有限责任公司 氧代丁醇酯化的多元羧酸聚甘油酯的制备方法
CN116917264A (zh) * 2020-07-13 2023-10-20 凯托利皮克斯治疗有限责任公司 羟基丁酸羧酸酯的制备方法
WO2022012766A1 (de) * 2020-07-13 2022-01-20 Ioi Oleo Gmbh Verfahren zur herstellung von oxobutanol-estern von polymeren carbonsäuren
CN112341542B (zh) * 2021-01-08 2021-05-14 清华大学 一种3-羟基丁酰化修饰蛋白质药物及其制备方法和应用
BR112023014818A2 (pt) * 2021-01-26 2023-10-03 Buck Inst Res Aging Uso de ésteres de cetona exógena para induzir perda de peso em mamíferos
US12059398B2 (en) * 2022-08-26 2024-08-13 Health Via Modern Nutrition Inc. Compositions of 1,3-butanediol and beta-hydroxybutyric acid to provide optimal therapeutic ketosis
US20250009707A1 (en) 2023-06-29 2025-01-09 BOPZ Nutrition Ltd. Methods of inducing ketosis in non-human mammals

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