CO2018014167A2 - Ésteres de ácidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y métodos para usar los mismos - Google Patents

Ésteres de ácidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y métodos para usar los mismos

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Publication number
CO2018014167A2
CO2018014167A2 CONC2018/0014167A CO2018014167A CO2018014167A2 CO 2018014167 A2 CO2018014167 A2 CO 2018014167A2 CO 2018014167 A CO2018014167 A CO 2018014167A CO 2018014167 A2 CO2018014167 A2 CO 2018014167A2
Authority
CO
Colombia
Prior art keywords
fatty acid
butanediol
acid esters
hydroxybutyrate
methods
Prior art date
Application number
CONC2018/0014167A
Other languages
English (en)
Inventor
Eric Verdin
Scott Ulrich
John Newman
Original Assignee
Univ California
The J David Gladstone Inst
Ithaca College
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Filing date
Publication date
Application filed by Univ California, The J David Gladstone Inst, Ithaca College filed Critical Univ California
Publication of CO2018014167A2 publication Critical patent/CO2018014167A2/es

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
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    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
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    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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Abstract

Los aspectos de la presente invención incluyen compuestos de ß-hidroxiéster de ácido graso (por ejemplo, ésteres de ácido graso de ß-hidroxibutirato), ésteres de ácido graso de butanodiol y sales farmacéuticamente aceptables de los mismos. También se proporcionan composiciones farmacéuticas que tienen uno o más compuestos de ß-hidroxiéster de ácido graso y/o uno o más ésteres de ácido graso de butanodiol. También se proporcionan los métodos para tratar un sujeto al administrar uno o más ésteres al sujeto. También se describen kits que contienen uno o más de los ésteres objetivo.
CONC2018/0014167A 2016-06-07 2018-12-26 Ésteres de ácidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y métodos para usar los mismos CO2018014167A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662346975P 2016-06-07 2016-06-07
PCT/US2017/035826 WO2017213999A1 (en) 2016-06-07 2017-06-02 Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same

Publications (1)

Publication Number Publication Date
CO2018014167A2 true CO2018014167A2 (es) 2019-01-18

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CONC2018/0014167A CO2018014167A2 (es) 2016-06-07 2018-12-26 Ésteres de ácidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y métodos para usar los mismos

Country Status (13)

Country Link
US (4) US10889538B2 (es)
EP (1) EP3465335A4 (es)
JP (3) JP7058610B2 (es)
KR (2) KR102638807B1 (es)
CN (2) CN114292190A (es)
AU (2) AU2017278099B2 (es)
CA (1) CA3026621A1 (es)
CO (1) CO2018014167A2 (es)
IL (2) IL263561B (es)
MX (2) MX2018015302A (es)
RU (1) RU2761829C2 (es)
SG (1) SG11201810765PA (es)
WO (1) WO2017213999A1 (es)

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