MX2018015302A - Esteres de acidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y metodos para usar los mismos. - Google Patents

Esteres de acidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y metodos para usar los mismos.

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Publication number
MX2018015302A
MX2018015302A MX2018015302A MX2018015302A MX2018015302A MX 2018015302 A MX2018015302 A MX 2018015302A MX 2018015302 A MX2018015302 A MX 2018015302A MX 2018015302 A MX2018015302 A MX 2018015302A MX 2018015302 A MX2018015302 A MX 2018015302A
Authority
MX
Mexico
Prior art keywords
fatty acid
butanediol
acid esters
hydroxybutyrate
methods
Prior art date
Application number
MX2018015302A
Other languages
English (en)
Inventor
Newman John
Verdin Eric
ULRICH Scott
Original Assignee
The J David Gladstone Inst
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Publication date
Application filed by The J David Gladstone Inst filed Critical The J David Gladstone Inst
Publication of MX2018015302A publication Critical patent/MX2018015302A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/045—Organic compounds containing nitrogen as heteroatom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • G—PHYSICS
    • G02—OPTICS
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Abstract

Los aspectos de la presente invención incluyen compuestos de ß-hidroxiéster de ácido graso (por ejemplo, ésteres de ácido graso de ß-hidroxibutirato), ésteres de ácido graso de butanodiol y sales farmacéuticamente aceptables de los mismos. También se proporcionan composiciones farmacéuticas que tienen uno o más compuestos de ß-hidroxiéster de ácido graso y/o uno o más ésteres de ácido graso de butanodiol. También se proporcionan los métodos para tratar un sujeto al administrar uno o más ésteres al sujeto. También se describen kits que contienen uno o más de los ésteres objetivo.
MX2018015302A 2016-06-07 2017-06-02 Esteres de acidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y metodos para usar los mismos. MX2018015302A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662346975P 2016-06-07 2016-06-07
PCT/US2017/035826 WO2017213999A1 (en) 2016-06-07 2017-06-02 Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same

Publications (1)

Publication Number Publication Date
MX2018015302A true MX2018015302A (es) 2019-08-22

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018015302A MX2018015302A (es) 2016-06-07 2017-06-02 Esteres de acidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y metodos para usar los mismos.
MX2021009806A MX2021009806A (es) 2016-06-07 2017-06-02 Ésteres de ácidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y métodos para usar los mismos.

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MX2021009806A MX2021009806A (es) 2016-06-07 2017-06-02 Ésteres de ácidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y métodos para usar los mismos.

Country Status (13)

Country Link
US (4) US10889538B2 (es)
EP (1) EP3465335A4 (es)
JP (3) JP7058610B2 (es)
KR (2) KR102638807B1 (es)
CN (2) CN114292190A (es)
AU (2) AU2017278099B2 (es)
CA (1) CA3026621A1 (es)
CO (1) CO2018014167A2 (es)
IL (2) IL263561B (es)
MX (2) MX2018015302A (es)
RU (1) RU2761829C2 (es)
SG (1) SG11201810765PA (es)
WO (1) WO2017213999A1 (es)

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MX2018015302A (es) 2016-06-07 2019-08-22 The J David Gladstone Inst Esteres de acidos grasos de cadena media de beta-hidroxibutirato y butanodiol y composiciones y metodos para usar los mismos.
KR20200029547A (ko) 2017-07-21 2020-03-18 버크 인스티튜트 포 리서치 온 에이징 베타-히드록시부티레이트 및 부탄디올의 s-거울상이성질체 및 이의 사용 방법
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EP3880644B1 (de) 2019-01-17 2023-09-06 KetoLipix Therapeutics GmbH Verfahren zur herstellung von verkappten 3-hydroxycarbonsäuren sowie deren salzen und estern
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