CN108220295B - PCSK9 iRNA组合物及其使用方法 - Google Patents

PCSK9 iRNA组合物及其使用方法 Download PDF

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CN108220295B
CN108220295B CN201810143112.0A CN201810143112A CN108220295B CN 108220295 B CN108220295 B CN 108220295B CN 201810143112 A CN201810143112 A CN 201810143112A CN 108220295 B CN108220295 B CN 108220295B
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rnai agent
nucleotides
double stranded
stranded rnai
strand
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CN108220295A (zh
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A·博罗多夫斯基
R·G·卡兰索塔蒂尔
K·菲茨杰拉德
M·弗兰克-卡米尼斯基
W·奎贝斯
M·迈尔
K·查里斯
S·库奇曼奇
M·玛诺哈兰
S·米尔斯泰恩
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Alnylam Pharmaceuticals Inc
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CN201810143112.0A 2012-12-05 2013-12-05 PCSK9 iRNA组合物及其使用方法 Active CN108220295B (zh)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201261733518P 2012-12-05 2012-12-05
US61/733,518 2012-12-05
US201361793530P 2013-03-15 2013-03-15
US61/793,530 2013-03-15
US201361886916P 2013-10-04 2013-10-04
US61/886,916 2013-10-04
US201361892188P 2013-10-17 2013-10-17
US61/892,188 2013-10-17
PCT/US2013/073349 WO2014089313A1 (en) 2012-12-05 2013-12-05 PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
CN201380063930.5A CN104854242B (zh) 2012-12-05 2013-12-05 PCSK9 iRNA组合物及其使用方法

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CN108220295B true CN108220295B (zh) 2022-09-02

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