CN108024544B - 用于核酸酶介导的基因组工程化的递送方法及组合物 - Google Patents
用于核酸酶介导的基因组工程化的递送方法及组合物 Download PDFInfo
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- CN108024544B CN108024544B CN201680052559.6A CN201680052559A CN108024544B CN 108024544 B CN108024544 B CN 108024544B CN 201680052559 A CN201680052559 A CN 201680052559A CN 108024544 B CN108024544 B CN 108024544B
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- A61K38/36—Blood coagulation or fibrinolysis factors
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- A61K40/31—Chimeric antigen receptors [CAR]
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- A61K40/4209—Hepatocyte growth factor receptor [HGFR] or c-met]
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0636—T lymphocytes
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- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
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- A61K2239/27—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by targeting or presenting multiple antigens
- A61K2239/29—Multispecific CARs
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
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- C12N2510/00—Genetically modified cells
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- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562191918P | 2015-07-13 | 2015-07-13 | |
| US62/191,918 | 2015-07-13 | ||
| US201562247469P | 2015-10-28 | 2015-10-28 | |
| US62/247,469 | 2015-10-28 | ||
| US201662315438P | 2016-03-30 | 2016-03-30 | |
| US62/315,438 | 2016-03-30 | ||
| PCT/US2016/042024 WO2017011519A1 (en) | 2015-07-13 | 2016-07-13 | Delivery methods and compositions for nuclease-mediated genome engineering |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108024544A CN108024544A (zh) | 2018-05-11 |
| CN108024544B true CN108024544B (zh) | 2022-04-29 |
Family
ID=57758305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680052559.6A Active CN108024544B (zh) | 2015-07-13 | 2016-07-13 | 用于核酸酶介导的基因组工程化的递送方法及组合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10450585B2 (enExample) |
| EP (1) | EP3322297B1 (enExample) |
| JP (2) | JP6954890B2 (enExample) |
| CN (1) | CN108024544B (enExample) |
| AU (1) | AU2016291778B2 (enExample) |
| CA (1) | CA2991301A1 (enExample) |
| WO (1) | WO2017011519A1 (enExample) |
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2016
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| CN1794995A (zh) * | 2003-05-27 | 2006-06-28 | 罗伯特·佩尔·黑格奎斯特 | 酪氨酸激酶抑制剂在治疗糖尿病中的用途 |
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| JP6954890B2 (ja) | 2021-10-27 |
| JP2018525979A (ja) | 2018-09-13 |
| CN108024544A (zh) | 2018-05-11 |
| AU2016291778A1 (en) | 2018-01-25 |
| AU2016291778B2 (en) | 2021-05-06 |
| US10450585B2 (en) | 2019-10-22 |
| US20200102577A1 (en) | 2020-04-02 |
| US20170016027A1 (en) | 2017-01-19 |
| EP3322297A4 (en) | 2019-04-17 |
| EP3322297B1 (en) | 2024-12-04 |
| WO2017011519A1 (en) | 2017-01-19 |
| JP2021045166A (ja) | 2021-03-25 |
| JP7348160B2 (ja) | 2023-09-20 |
| EP3322297A1 (en) | 2018-05-23 |
| CA2991301A1 (en) | 2017-01-19 |
| EP3322297C0 (en) | 2024-12-04 |
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