CN107129524B - 用于抑制微生物细胞的疫苗和疫苗组分 - Google Patents

用于抑制微生物细胞的疫苗和疫苗组分 Download PDF

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CN107129524B
CN107129524B CN201611216760.1A CN201611216760A CN107129524B CN 107129524 B CN107129524 B CN 107129524B CN 201611216760 A CN201611216760 A CN 201611216760A CN 107129524 B CN107129524 B CN 107129524B
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peptide
sequence
polypeptide
antibodies
cells
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CN107129524A (zh
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E·H·阿特曼
G·T·爱特伍德
D·李
W·J·凯利
Z·孔
S·C·利伊
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Pastoral Greenhouse Research Ltd
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641Cysteine endopeptidases (3.4.22)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/20Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
    • Y02P60/22Methane [CH4], e.g. from rice paddies

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CN201611216760.1A 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分 Active CN107129524B (zh)

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CN201611216760.1A CN107129524B (zh) 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分

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US97510407P 2007-09-25 2007-09-25
US60/975,104 2007-09-25
US98984107P 2007-11-22 2007-11-22
US98984007P 2007-11-22 2007-11-22
US60/989,841 2007-11-22
US60/989,840 2007-11-22
PCT/NZ2008/000249 WO2009041832A2 (en) 2007-09-25 2008-09-25 Vaccines and vaccine components for inhibition of microbial cells
CN201611216760.1A CN107129524B (zh) 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分
CN2008801094507A CN102015755A (zh) 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分

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CN107129524B true CN107129524B (zh) 2023-11-21

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CN200880109156.6A Active CN101932595B (zh) 2007-09-25 2008-09-25 噬菌体φmru多核苷酸和多肽及其应用
CN201611216760.1A Active CN107129524B (zh) 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分
CN200880109364.6A Active CN101918431B (zh) 2007-09-25 2008-09-25 用于微生物细胞的细胞通透肽和多肽
CN2008801094507A Pending CN102015755A (zh) 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分

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CN200880109364.6A Active CN101918431B (zh) 2007-09-25 2008-09-25 用于微生物细胞的细胞通透肽和多肽
CN2008801094507A Pending CN102015755A (zh) 2007-09-25 2008-09-25 用于抑制微生物细胞的疫苗和疫苗组分

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CN (4) CN101932595B (enExample)
AR (3) AR068551A1 (enExample)
AU (4) AU2008304018A1 (enExample)
BR (5) BRPI0817299A8 (enExample)
CA (3) CA2700164C (enExample)
CL (3) CL2008002860A1 (enExample)
DK (3) DK3327030T3 (enExample)
ES (3) ES2587595T3 (enExample)
MX (3) MX340736B (enExample)
NZ (1) NZ745324A (enExample)
RU (1) RU2528854C2 (enExample)
UY (3) UY31359A1 (enExample)
WO (3) WO2009041830A2 (enExample)
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Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0817299A8 (pt) 2007-09-25 2019-01-29 Pastoral Greenhouse Gas Res Limited vacinas e componentes de vacina para inibição de células microbianas
GB0815484D0 (en) 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
SG177370A1 (en) * 2009-06-26 2012-02-28 Univ Leuven Kath Antimicrobial agents
BRPI1015203B1 (pt) * 2009-06-26 2021-06-01 Lysando Ag Proteína de fusão composta por uma endolisina e uma extensão de peptídeo anfifática, usos da mesma e composição farmacêutica que compreende a dita proteína
NZ750559A (en) * 2009-08-27 2023-01-27 Pastoral Greenhouse Gas Res Ltd Complete genome sequence of the methanogen methanobrevibacter ruminantium
MX340520B (es) * 2010-04-27 2016-07-12 Lysando Ag * Metodo de reduccion de biopeliculas.
TWI655204B (zh) * 2012-09-19 2019-04-01 韓商傑姆維克斯&凱爾有限公司 穿膜胜肽以及包含該胜肽之共軛物及組成物(三)
JP2016505256A (ja) * 2012-12-12 2016-02-25 ザ・ブロード・インスティテュート・インコーポレイテッ 配列操作のためのCRISPR−Cas成分系、方法および組成物
US10760064B2 (en) 2013-03-15 2020-09-01 The General Hospital Corporation RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
KR102271292B1 (ko) 2013-03-15 2021-07-02 더 제너럴 하스피탈 코포레이션 Rna-안내 게놈 편집의 특이성을 증가시키기 위한 rna-안내 foki 뉴클레아제(rfn)의 용도
WO2014204578A1 (en) 2013-06-21 2014-12-24 The General Hospital Corporation Using rna-guided foki nucleases (rfns) to increase specificity for rna-guided genome editing
CN111218447B (zh) 2013-11-07 2024-10-11 爱迪塔斯医药有限公司 使用统治型gRNA的CRISPR相关方法和组合物
WO2016073433A1 (en) * 2014-11-06 2016-05-12 E. I. Du Pont De Nemours And Company Peptide-mediated delivery of rna-guided endonuclease into cells
CN104789675A (zh) * 2015-04-15 2015-07-22 江苏师范大学 一种检测荷斯坦奶牛瘤胃微生物的方法
EP3292219B9 (en) * 2015-05-04 2022-05-18 Ramot at Tel-Aviv University Ltd. Methods and kits for fragmenting dna
US9926546B2 (en) 2015-08-28 2018-03-27 The General Hospital Corporation Engineered CRISPR-Cas9 nucleases
US9512446B1 (en) 2015-08-28 2016-12-06 The General Hospital Corporation Engineered CRISPR-Cas9 nucleases
MX2019000621A (es) * 2016-07-14 2019-08-01 Basf Se Medio de fermentacion que comprende agente quelante.
EP3565904A1 (en) * 2016-12-29 2019-11-13 Illumina, Inc. Analysis system for orthogonal access to and tagging of biomolecules in cellular compartments
CN112986589B (zh) * 2017-01-05 2023-01-24 深圳迈瑞生物医疗电子股份有限公司 网织红细胞模拟粒子、血小板模拟粒子制备方法及质控物
US10745439B2 (en) * 2017-03-20 2020-08-18 Regents Of The University Of Minnesota Kinase substrates and methods of use thereof
US20190233816A1 (en) 2018-01-26 2019-08-01 Massachusetts Institute Of Technology Structure-guided chemical modification of guide rna and its applications
WO2019183123A1 (en) * 2018-03-19 2019-09-26 Regeneron Pharmaceuticals, Inc. Transcription modulation in animals using crispr/cas systems
EP3880227A4 (en) 2018-11-14 2022-11-09 RubrYc Therapeutics, Inc. ANTI-CD25 ANTIBODIES
CN113646330A (zh) 2018-11-14 2021-11-12 鲁比克治疗股份有限公司 工程化cd25多肽及其用途
CN109627301B (zh) * 2019-02-18 2022-08-05 浙江新银象生物工程有限公司 Nisin固体稳定剂开发及应用
CN115942932A (zh) * 2020-03-19 2023-04-07 迈克瑞欧斯人体健康有限公司 感兴趣的稳定蛋白
WO2021207687A1 (en) * 2020-04-10 2021-10-14 Liberty Biosecurity Llc Polypeptide compositions and uses thereof
CN112143747B (zh) * 2020-09-09 2022-09-13 昆明理工大学 一种噬菌体裂解酶及其基因、基因重组表达载体与应用
DK4037666T3 (da) 2020-12-08 2024-06-24 Ruminant Biotech Corp Ltd Forbedring af anordninger og fremgangsmåder til indgivelse af substanser til dyr
CN112961217B (zh) * 2021-03-19 2022-11-08 江苏元本生物科技有限公司 一种靶向Siglec-15的噬菌体多肽
CN113121705B (zh) * 2021-04-19 2023-03-24 成都英普博集生物科技有限公司 用于制备短肽混合物的融合蛋白、目的多肽、短肽混合物的制备方法及应用
US20240009291A1 (en) * 2022-07-11 2024-01-11 Arkea Bio Corp. Compositions and methods for reducing methane emissions in ruminant populations
CN115417927A (zh) * 2022-09-08 2022-12-02 南京松天盛科生物科技有限公司 小鼠腹水致敏物及其应用
KR20250099155A (ko) * 2022-11-03 2025-07-01 헬릭스 나노테크놀로지스 인코포레이티드 반추위 및 메탄 생성 미생물 백신 및 이의 용도
CN115938486B (zh) * 2022-12-06 2023-11-10 内蒙古农业大学 基于图神经网络的抗菌性乳酸菌株筛选方法
WO2025219570A1 (en) 2024-04-17 2025-10-23 Johannes Kepler Universität Linz Composition for inhibiting protein translocation and methods using the same
WO2025233675A1 (en) * 2024-05-10 2025-11-13 Institut Pasteur Use of talosaminidase to regulate populations of archaeal methanogens in industrial, agricultural and medical settings

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1658768A (zh) * 2002-05-14 2005-08-24 阿克佐诺贝尔公司 减少动物消化活动所释放的甲烷的产生的方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US159861A (en) * 1875-02-16 Improvement in brooms
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
IE57352B1 (en) * 1983-05-03 1992-08-12 Ssm Int Chem Co Ltd Composition having improved pharmaceutical activity and use of it for veterinary purposes
GB8815968D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Veterinary devices
JPH05219927A (ja) * 1992-02-14 1993-08-31 Gumma Pref Gov 飼料の混合装置及び混合飼料の製造方法
JP3651915B2 (ja) * 1993-06-30 2005-05-25 財団法人神奈川科学技術アカデミー シグナル配列ペプチドをコードするdna断片の探索法及びそのためのベクター
US6036950A (en) 1993-10-19 2000-03-14 Commonwealth Scientific And Industrial Research Organisation Method for improving utilisation of nutrients by ruminant or ruminant-like animals
DE69433180T2 (de) 1993-10-26 2004-06-24 Affymetrix, Inc., Santa Clara Felder von nukleinsaeuresonden auf biologischen chips
DK0739198T3 (da) 1994-01-20 2004-01-26 Agres Ltd Anordning til indgivelse af gavnlige materialer til drøvtyggere
NZ278977A (en) 1994-01-20 1997-03-24 Pastoral Agric Res Inst Nz Ltd Sustained release bolus for ruminants
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
AUPN353695A0 (en) 1995-06-14 1995-07-06 Commonwealth Scientific And Industrial Research Organisation Immunogenic preparation and method for improving the productivity of ruminant animals
WO1998007830A2 (en) * 1996-08-22 1998-02-26 The Institute For Genomic Research COMPLETE GENOME SEQUENCE OF THE METHANOGENIC ARCHAEON, $i(METHANOCOCCUS JANNASCHII)
US5985907A (en) * 1998-08-12 1999-11-16 Health Research, Inc. Method for inhibiting growth of methanogens
WO2002077183A2 (en) 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
AU2002326949A1 (en) 2001-09-18 2003-05-12 The Board Of Regents Of The University Of Nebraska Method for the inhibition of methanogenesis
US7314974B2 (en) * 2002-02-21 2008-01-01 Monsanto Technology, Llc Expression of microbial proteins in plants for production of plants with improved properties
WO2003076575A2 (en) * 2002-03-04 2003-09-18 Fidelity Systems, Inc., Et Al. The complete genome and protein sequence of the hyperthermophile methanopyrus kandleri av19 and monophyly of archael methanogens and methods of use thereof
US20100048595A1 (en) 2005-03-23 2010-02-25 Washington University In St. Louis Use of archaea to modulate the nutrient harvesting functions of the gastrointestinal microbiota
BRPI0817299A8 (pt) * 2007-09-25 2019-01-29 Pastoral Greenhouse Gas Res Limited vacinas e componentes de vacina para inibição de células microbianas
CN101434924A (zh) * 2008-12-17 2009-05-20 中南大学 一种分离严格厌氧产甲烷古菌的方法
NZ750559A (en) * 2009-08-27 2023-01-27 Pastoral Greenhouse Gas Res Ltd Complete genome sequence of the methanogen methanobrevibacter ruminantium
CN101864362B (zh) * 2010-05-19 2012-05-09 江苏加德绿色能源有限公司 一种复合微生物菌剂及其应用
DE102011119230B4 (de) * 2011-11-23 2013-07-11 Audi Ag Kraftwagen-Blinkleuchte und Verfahren zum Betreiben einer Blinkleuchte
WO2014100726A2 (en) * 2012-12-21 2014-06-26 Danisco Us Inc. Production of isoprene, isoprenoid, and isoprenoid precursors using an alternative lower mevalonate pathway

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1658768A (zh) * 2002-05-14 2005-08-24 阿克佐诺贝尔公司 减少动物消化活动所释放的甲烷的产生的方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A5UKV2;Samuel B. S. et al.;《EMBL》;20071002;Sequence部分 *
Effects of the Fusarium spp. mycotoxins fusaric acid and deoxynivalenol on the growth of Ruminococcus albus and Methanobrevibacter ruminantium;May, H. D. et al.;《CANADIAN JOURNAL OF MICROBIOLOGY》;20000705;第46卷(第8期);第692-699页 *
Samuel B. S. et al..A5UKV2.《EMBL》.2007,Sequence部分. *
产甲烷菌的研究进展;郝鲜俊等;《贵州农业科学》;20070215;第35卷(第1期);第111-113页 *
郑元景等.甲烷菌.《污水厌氧生物处理》.中国建筑工业出版社,1988,第62-64页. *

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