CL2008002859A1 - Péptido señal con actividad de permeabilización de células microbianas; vector; célula huésped; molécula conjugada que lo comprende; y método para permeabilizar una célula microbiana. - Google Patents
Péptido señal con actividad de permeabilización de células microbianas; vector; célula huésped; molécula conjugada que lo comprende; y método para permeabilizar una célula microbiana.Info
- Publication number
- CL2008002859A1 CL2008002859A1 CL2008002859A CL2008002859A CL2008002859A1 CL 2008002859 A1 CL2008002859 A1 CL 2008002859A1 CL 2008002859 A CL2008002859 A CL 2008002859A CL 2008002859 A CL2008002859 A CL 2008002859A CL 2008002859 A1 CL2008002859 A1 CL 2008002859A1
- Authority
- CL
- Chile
- Prior art keywords
- microbial cell
- cell
- permeabilizing
- vector
- signal peptide
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title abstract 3
- 239000013598 vector Substances 0.000 title abstract 3
- 108010076504 Protein Sorting Signals Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000008823 permeabilization Effects 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- -1 POLIPEPTIDES Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000000696 methanogenic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/641—Cysteine endopeptidases (3.4.22)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/20—Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
- Y02P60/22—Methane [CH4], e.g. from rice paddies
Abstract
PÉPTIDOS SEÑAL Y POLIPÉPTIDOS QUE COMPRENDEN ESTOS PÉPTIDOS, ASÍ COMO POLINUCLEÓTIDOS QUE CODIFICAN ESTOS PÉPTIDOS O POLIPÉPTIDOS. VECTORES DE EXPRESIÓN QUE COMPRENDEN ESTOS POLINUCLEÓTIDOS Y CÉLULAS HUÉSPED QUE COMPRENDEN ESTOS VECTORES. COMPOSICIONES Y MÉTODOS PARA LA DETECCIÓN, SELECCIÓN COMO BLANCO, PERMEABILIZACIÓN E INHIBICIÓN DE CÉIULAS MICROBIANAS, ESPECIALMENTE CÉLULAS METANÓGENAS, UTILIZANDO LOS PÉPTIDOS, POLIPÉPTIDOS, POLINUCLEÓTIDOS, VECTORES DE EXPRESIÓN O CÉLULAS HUÉSPED DESCRIPTOS.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97510407P | 2007-09-25 | 2007-09-25 | |
US98984007P | 2007-11-22 | 2007-11-22 | |
US98984107P | 2007-11-22 | 2007-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008002859A1 true CL2008002859A1 (es) | 2009-03-06 |
Family
ID=40511642
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008002861A CL2008002861A1 (es) | 2007-09-25 | 2008-09-25 | Polipeptido aislado de m. ruminantium; vector, molecula conjugada y celula huesped que comprenden dicho polipeptido; anticuerpo o fragmento que se une al polipeptido; composicion farmaceutica que comprende la molecula conjugada; metodo para dirigir una celula metanogena para identificacion, aislamiento o inhibicion. |
CL2008002860A CL2008002860A1 (es) | 2007-09-25 | 2008-09-25 | Polipeptido; polinucleotido que lo codifica; vector y fago aislado que comprenda este polinucleotido; anticuerpo que se une a este polipeptido; molecula de fusion que comprende este polipeptido; celula huesped metanogena que comprende el vector; composicion farmaceutica que comprende el polinucleotido. |
CL2008002859A CL2008002859A1 (es) | 2007-09-25 | 2008-09-25 | Péptido señal con actividad de permeabilización de células microbianas; vector; célula huésped; molécula conjugada que lo comprende; y método para permeabilizar una célula microbiana. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008002861A CL2008002861A1 (es) | 2007-09-25 | 2008-09-25 | Polipeptido aislado de m. ruminantium; vector, molecula conjugada y celula huesped que comprenden dicho polipeptido; anticuerpo o fragmento que se une al polipeptido; composicion farmaceutica que comprende la molecula conjugada; metodo para dirigir una celula metanogena para identificacion, aislamiento o inhibicion. |
CL2008002860A CL2008002860A1 (es) | 2007-09-25 | 2008-09-25 | Polipeptido; polinucleotido que lo codifica; vector y fago aislado que comprenda este polinucleotido; anticuerpo que se une a este polipeptido; molecula de fusion que comprende este polipeptido; celula huesped metanogena que comprende el vector; composicion farmaceutica que comprende el polinucleotido. |
Country Status (17)
Country | Link |
---|---|
US (7) | US9296789B2 (es) |
EP (5) | EP3327030B1 (es) |
JP (5) | JP6067209B2 (es) |
CN (4) | CN101932595B (es) |
AR (3) | AR068552A1 (es) |
AU (4) | AU2008305846A1 (es) |
BR (5) | BRPI0817312B1 (es) |
CA (3) | CA2700162C (es) |
CL (3) | CL2008002861A1 (es) |
DK (3) | DK2203466T3 (es) |
ES (3) | ES2895908T3 (es) |
MX (3) | MX2010003328A (es) |
NZ (1) | NZ745324A (es) |
RU (1) | RU2528854C2 (es) |
UY (3) | UY31359A1 (es) |
WO (3) | WO2009041832A2 (es) |
ZA (1) | ZA201001933B (es) |
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RU2528854C2 (ru) * | 2007-09-25 | 2014-09-20 | Пасторал Гринхаус Гэз Рисерч Лтд | Вакцины и компоненты вакцин для подавления микробных клеток |
GB0815484D0 (en) | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
JP6034188B2 (ja) | 2009-06-26 | 2016-11-30 | ライサンド アクツィエンゲゼルシャフト | 抗微生物剤 |
ES2579806T3 (es) * | 2009-06-26 | 2016-08-16 | Katholieke Universiteit Leuven, K.U. Leuven R&D | Agentes antimicrobianos |
BR112012004308A2 (pt) | 2009-08-27 | 2015-09-01 | Pastoral Greenhouse Gas Res Ltd | Sequência do genoma completo do metanógeno methanobrevibacter ruminantium |
SG184836A1 (en) * | 2010-04-27 | 2012-11-29 | Lysando Ag | Method of reducing biofilms |
CN110074997B (zh) * | 2012-09-19 | 2022-07-08 | 珍白斯凯尔有限公司 | 细胞穿透肽、包含该肽的缀合物、及包含该缀合物的组合物 |
CN112301024A (zh) | 2013-03-15 | 2021-02-02 | 通用医疗公司 | 使用RNA引导的FokI核酸酶(RFN)提高RNA引导的基因组编辑的特异性 |
WO2014204578A1 (en) | 2013-06-21 | 2014-12-24 | The General Hospital Corporation | Using rna-guided foki nucleases (rfns) to increase specificity for rna-guided genome editing |
US10760064B2 (en) | 2013-03-15 | 2020-09-01 | The General Hospital Corporation | RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci |
DK3066201T3 (en) | 2013-11-07 | 2018-06-06 | Editas Medicine Inc | CRISPR-RELATED PROCEDURES AND COMPOSITIONS WITH LEADING GRADES |
DK3597740T3 (da) * | 2014-11-06 | 2022-06-20 | Dupont Us Holding Llc | Peptidmedieret indføring af rna-styret endonuklease i celler |
CN104789675A (zh) * | 2015-04-15 | 2015-07-22 | 江苏师范大学 | 一种检测荷斯坦奶牛瘤胃微生物的方法 |
US11845928B2 (en) * | 2015-05-04 | 2023-12-19 | Tsinghua University | Methods and kits for fragmenting DNA |
US9926546B2 (en) | 2015-08-28 | 2018-03-27 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
US9512446B1 (en) | 2015-08-28 | 2016-12-06 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
MX2019000621A (es) * | 2016-07-14 | 2019-08-01 | Basf Se | Medio de fermentacion que comprende agente quelante. |
JP7234114B2 (ja) * | 2016-12-29 | 2023-03-07 | イルミナ インコーポレイテッド | 細胞区画内の生体分子への直交アクセスおよび細胞区画内の生体分子のタグ付けのための分析システム |
WO2018126499A1 (zh) * | 2017-01-05 | 2018-07-12 | 深圳迈瑞生物医疗电子股份有限公司 | 网织红细胞模拟粒子、血小板模拟粒子制备方法及质控物 |
US10745439B2 (en) * | 2017-03-20 | 2020-08-18 | Regents Of The University Of Minnesota | Kinase substrates and methods of use thereof |
WO2019147743A1 (en) | 2018-01-26 | 2019-08-01 | Massachusetts Institute Of Technology | Structure-guided chemical modification of guide rna and its applications |
CA3089331A1 (en) * | 2018-03-19 | 2019-09-26 | Regeneron Pharmaceuticals, Inc. | Transcription modulation in animals using crispr/cas systems |
EP3880227A4 (en) * | 2018-11-14 | 2022-11-09 | RubrYc Therapeutics, Inc. | CD25 ANTIBODIES |
CN109627301B (zh) * | 2019-02-18 | 2022-08-05 | 浙江新银象生物工程有限公司 | Nisin固体稳定剂开发及应用 |
CN112143747B (zh) * | 2020-09-09 | 2022-09-13 | 昆明理工大学 | 一种噬菌体裂解酶及其基因、基因重组表达载体与应用 |
EP4037666B1 (en) | 2020-12-08 | 2024-05-01 | Ruminant Biotech Corp Limited | Improvements to devices and methods for delivery of substances to animals |
CN112961217B (zh) * | 2021-03-19 | 2022-11-08 | 江苏元本生物科技有限公司 | 一种靶向Siglec-15的噬菌体多肽 |
CN113121705B (zh) * | 2021-04-19 | 2023-03-24 | 成都英普博集生物科技有限公司 | 用于制备短肽混合物的融合蛋白、目的多肽、短肽混合物的制备方法及应用 |
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2008
- 2008-09-25 RU RU2010116163/10A patent/RU2528854C2/ru not_active IP Right Cessation
- 2008-09-25 CA CA2700162A patent/CA2700162C/en active Active
- 2008-09-25 MX MX2010003328A patent/MX2010003328A/es active IP Right Grant
- 2008-09-25 US US12/678,976 patent/US9296789B2/en active Active
- 2008-09-25 EP EP17206527.8A patent/EP3327030B1/en active Active
- 2008-09-25 US US12/678,925 patent/US8586709B2/en active Active
- 2008-09-25 UY UY31359A patent/UY31359A1/es not_active Application Discontinuation
- 2008-09-25 MX MX2010003319A patent/MX340736B/es active IP Right Grant
- 2008-09-25 CN CN200880109156.6A patent/CN101932595B/zh active Active
- 2008-09-25 CA CA2700129A patent/CA2700129C/en active Active
- 2008-09-25 AR ARP080104172A patent/AR068552A1/es unknown
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