UY31359A1 - Polinucleotidos y polipeptidos del fago qmru y sus usos - Google Patents

Polinucleotidos y polipeptidos del fago qmru y sus usos

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Publication number
UY31359A1
UY31359A1 UY31359A UY31359A UY31359A1 UY 31359 A1 UY31359 A1 UY 31359A1 UY 31359 A UY31359 A UY 31359A UY 31359 A UY31359 A UY 31359A UY 31359 A1 UY31359 A1 UY 31359A1
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Uruguay
Prior art keywords
polypeptides
phage
cells
relates
qmru
Prior art date
Application number
UY31359A
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English (en)
Inventor
Moon Christina Diane
Sang Carrie
Tootill Catherine Mary
Dey Debjit
Schofield Linley Rose
Ronimus Robert Starr
Leahy Sinead
Kong Zhanhao
Kelly William John
Dong Li
Attwood Graeme Trevor
Altermann Eric Heinz
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Publication date
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Publication of UY31359A1 publication Critical patent/UY31359A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641Cysteine endopeptidases (3.4.22)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/20Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
    • Y02P60/22Methane [CH4], e.g. from rice paddies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)

Abstract

La invención se refiere a composiciones y a métodos para introducir moléculas inhibidoras en células microbianas, en particular, células metanógenas. Especialmente, la invención se refiere a fagos pmru identtificados recientemente, incluso a inducción fágica, a partículas fágicas y al genoma fágico, así como a polipéptidos fágicos y a polinucleótidos que codifican dichos polipéptidos. La invención se relaciona asimismo con vectores de expresión y con células anfitrionas para producir dichos polipéptidos. La invención también se refiere a métodos para detectar, dirigirse a e inhibir células microbianas, en especial células metanógenas, mediante la utilización del fago, los polipéptidos, los polinucleótidos, los vectores de expresión o las células anfitrionas descritos.
UY31359A 2007-09-25 2008-09-25 Polinucleotidos y polipeptidos del fago qmru y sus usos UY31359A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97510407P 2007-09-25 2007-09-25
US98984007P 2007-11-22 2007-11-22
US98984107P 2007-11-22 2007-11-22

Publications (1)

Publication Number Publication Date
UY31359A1 true UY31359A1 (es) 2009-04-30

Family

ID=40511642

Family Applications (3)

Application Number Title Priority Date Filing Date
UY31361A UY31361A1 (es) 2007-09-25 2008-09-25 Vacunas y componentes para inhibir celulas microbianas
UY31359A UY31359A1 (es) 2007-09-25 2008-09-25 Polinucleotidos y polipeptidos del fago qmru y sus usos
UY31360A UY31360A1 (es) 2007-09-25 2008-09-25 Peptidos y polipeptidos permeabilizadores de celulas para celulas microbianas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UY31361A UY31361A1 (es) 2007-09-25 2008-09-25 Vacunas y componentes para inhibir celulas microbianas

Family Applications After (1)

Application Number Title Priority Date Filing Date
UY31360A UY31360A1 (es) 2007-09-25 2008-09-25 Peptidos y polipeptidos permeabilizadores de celulas para celulas microbianas

Country Status (17)

Country Link
US (7) US8586709B2 (es)
EP (5) EP3936516A1 (es)
JP (5) JP6067209B2 (es)
CN (4) CN101932595B (es)
AR (3) AR068551A1 (es)
AU (4) AU2008304019A1 (es)
BR (5) BR122020023381B1 (es)
CA (3) CA2700162C (es)
CL (3) CL2008002861A1 (es)
DK (3) DK2203466T3 (es)
ES (3) ES2625144T3 (es)
MX (3) MX340736B (es)
NZ (2) NZ780936A (es)
RU (1) RU2528854C2 (es)
UY (3) UY31361A1 (es)
WO (3) WO2009041830A2 (es)
ZA (1) ZA201001933B (es)

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EP3327030A1 (en) 2018-05-30
EP2203470A2 (en) 2010-07-07
US20200325180A1 (en) 2020-10-15
DK2203467T3 (en) 2017-03-27
JP2010539927A (ja) 2010-12-24
MX340736B (es) 2016-07-22
JP5558356B2 (ja) 2014-07-23
CA2700129C (en) 2021-07-20
JP6067209B2 (ja) 2017-01-25
ES2895908T3 (es) 2022-02-23
AU2014210649A1 (en) 2014-09-04
JP2010539926A (ja) 2010-12-24
AR068553A1 (es) 2009-11-18
WO2009041832A3 (en) 2009-06-11
WO2009041830A3 (en) 2009-07-02
WO2009041831A1 (en) 2009-04-02
CA2700162A1 (en) 2009-04-02
EP2203470A4 (en) 2011-04-13
MX2010003321A (es) 2010-08-03
AU2008304018A1 (en) 2009-04-02
BRPI0817299A2 (pt) 2015-06-16
AU2008304019A1 (en) 2009-04-02
US20210332087A1 (en) 2021-10-28
EP2203467B1 (en) 2016-12-14
ZA201001933B (en) 2013-10-30
JP2017046704A (ja) 2017-03-09
NZ745324A (en) 2023-02-24
AU2014210649B2 (en) 2016-09-08
CN107129524A (zh) 2017-09-05
RU2528854C2 (ru) 2014-09-20
CN101918431B (zh) 2014-10-08
AR068552A1 (es) 2009-11-18
US20100209999A1 (en) 2010-08-19
EP2203466A2 (en) 2010-07-07
US20170342112A1 (en) 2017-11-30
MX2010003328A (es) 2010-08-16
EP2203466B1 (en) 2016-04-06
BR122021010737B1 (pt) 2021-09-21
CL2008002861A1 (es) 2009-03-06
ES2587595T3 (es) 2016-10-25
CN101932595B (zh) 2016-02-10
BR122021010729B1 (pt) 2022-02-15
MX2010003319A (es) 2010-09-10
CL2008002859A1 (es) 2009-03-06
CN102015755A (zh) 2011-04-13
WO2009041831A9 (en) 2009-11-05
WO2009041830A2 (en) 2009-04-02
CA2700164C (en) 2018-05-29
RU2010116163A (ru) 2011-11-10
BRPI0817312A2 (pt) 2015-03-17
NZ780936A (en) 2024-08-30
CN101918431A (zh) 2010-12-15
BRPI0817299A8 (pt) 2019-01-29
EP2203466A4 (en) 2011-04-13
WO2009041832A9 (en) 2009-10-22
US11926647B2 (en) 2024-03-12
JP5552053B2 (ja) 2014-07-16
UY31361A1 (es) 2009-04-30
ES2625144T3 (es) 2017-07-18
JP2010539928A (ja) 2010-12-24
CA2700164A1 (en) 2009-04-02
US20100221185A1 (en) 2010-09-02
CN101932595A (zh) 2010-12-29
EP2203467A4 (en) 2011-04-13
DK2203466T3 (en) 2016-07-25
WO2009041830A9 (en) 2009-08-27
US10995120B2 (en) 2021-05-04
CA2700129A1 (en) 2009-04-02
US10590170B2 (en) 2020-03-17
AU2008305846A1 (en) 2009-04-02
CL2008002860A1 (es) 2009-06-05
AR068551A1 (es) 2009-11-18
US9296789B2 (en) 2016-03-29
US8586709B2 (en) 2013-11-19
BRPI0817312B1 (pt) 2018-05-29
WO2009041832A2 (en) 2009-04-02
JP2015042166A (ja) 2015-03-05
EP3327030B1 (en) 2021-07-21
EP2203467A1 (en) 2010-07-07
US8592556B2 (en) 2013-11-26
US20100209998A1 (en) 2010-08-19
CN107129524B (zh) 2023-11-21
DK3327030T3 (da) 2021-10-04
BR122020023381B1 (pt) 2021-09-08
EP3936516A1 (en) 2022-01-12
UY31360A1 (es) 2009-04-30
CA2700162C (en) 2018-08-14
US20140220636A1 (en) 2014-08-07

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