CN107108707A - 高亲和力pd‑1药剂以及使用方法 - Google Patents

高亲和力pd‑1药剂以及使用方法 Download PDF

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Publication number
CN107108707A
CN107108707A CN201580054333.5A CN201580054333A CN107108707A CN 107108707 A CN107108707 A CN 107108707A CN 201580054333 A CN201580054333 A CN 201580054333A CN 107108707 A CN107108707 A CN 107108707A
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amino acid
affinity
protein
cell
relative
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阿龙·迈克尔·林
安德鲁·克鲁瑟
阿施施·曼格里克
欧文·L·韦斯曼
罗伊·路易斯·莫特
梅丽莎·N·麦克拉肯
辛迪·戈登
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Leland Stanford Junior University
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Leland Stanford Junior University
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CN201580054333.5A 2014-08-08 2015-08-07 高亲和力pd‑1药剂以及使用方法 Pending CN107108707A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462035316P 2014-08-08 2014-08-08
US62/035,316 2014-08-08
US201562150789P 2015-04-21 2015-04-21
US62/150,789 2015-04-21
PCT/US2015/044356 WO2016022994A2 (en) 2014-08-08 2015-08-07 High affinity pd-1 agents and methods of use

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CN107108707A true CN107108707A (zh) 2017-08-29

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US (5) US9546206B2 (https=)
EP (2) EP3177640B1 (https=)
JP (1) JP6945444B2 (https=)
CN (1) CN107108707A (https=)
CA (1) CA2994927A1 (https=)
CY (1) CY1123385T1 (https=)
DK (1) DK3177640T3 (https=)
ES (1) ES2819451T3 (https=)
HR (1) HRP20201153T1 (https=)
HU (1) HUE050406T2 (https=)
PL (1) PL3177640T3 (https=)
PT (1) PT3177640T (https=)
WO (1) WO2016022994A2 (https=)

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CN107916255A (zh) * 2017-11-16 2018-04-17 复旦大学 Pdl‑1基因靶向特异性甲基化表观遗传修饰抗肿瘤分子及其用途
CN108289966A (zh) * 2015-09-24 2018-07-17 北卡罗来纳-查佩尔山大学 用于减少转移的方法和组合物
CN108794619A (zh) * 2018-05-31 2018-11-13 郑州大学 一种高亲和pd-1蛋白突变体
CN108997492A (zh) * 2018-07-19 2018-12-14 海珂分子(北京)科技有限责任公司 高亲和力的pd1胞外区突变体多肽及相关融合蛋白
CN110054701A (zh) * 2019-04-17 2019-07-26 中国医学科学院血液病医院(血液学研究所) 一种基于间充质干细胞的抗肿瘤靶向给药系统及其应用
CN111100199A (zh) * 2018-12-29 2020-05-05 北京百普赛斯生物科技有限公司 一种荧光素标记的蛋白四聚体及其制备方法与应用
CN111714618A (zh) * 2019-03-22 2020-09-29 广东香雪精准医疗技术有限公司 T细胞和高亲和力pd-1融合蛋白的组合
WO2021013274A3 (zh) * 2019-07-22 2021-03-11 北京助天科技发展有限公司 一种嵌合抗原受体及其应用
CN112543767A (zh) * 2018-07-11 2021-03-23 卡尔医学有限公司 Pd1-4-1bbl变体融合蛋白及其使用方法
CN115884988A (zh) * 2020-05-28 2023-03-31 小利兰·斯坦福大学托管委员会 防止封闭和半封闭空间中病毒和微生物污染的雾化粘液抑制纳米抗体
WO2024066616A1 (zh) * 2022-09-27 2024-04-04 北京大学 一种高亲和力pd1蛋白偶联物及其应用

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