CN106666728A - Special clinical nutrient composition for gestational diabetes and preparation method of nutrient composition - Google Patents
Special clinical nutrient composition for gestational diabetes and preparation method of nutrient composition Download PDFInfo
- Publication number
- CN106666728A CN106666728A CN201611209080.7A CN201611209080A CN106666728A CN 106666728 A CN106666728 A CN 106666728A CN 201611209080 A CN201611209080 A CN 201611209080A CN 106666728 A CN106666728 A CN 106666728A
- Authority
- CN
- China
- Prior art keywords
- parts
- gestational diabetes
- diabetes mellitus
- powder
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000004104 gestational diabetes Diseases 0.000 title claims abstract description 66
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 235000015097 nutrients Nutrition 0.000 title abstract description 21
- 235000016709 nutrition Nutrition 0.000 claims abstract description 47
- 230000035764 nutrition Effects 0.000 claims abstract description 43
- 239000011782 vitamin Substances 0.000 claims abstract description 37
- 235000013305 food Nutrition 0.000 claims abstract description 32
- 241000196324 Embryophyta Species 0.000 claims abstract description 24
- 235000013325 dietary fiber Nutrition 0.000 claims abstract description 24
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 24
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 24
- 150000001875 compounds Chemical class 0.000 claims abstract description 22
- 229940088594 vitamin Drugs 0.000 claims abstract description 22
- 229930003231 vitamin Natural products 0.000 claims abstract description 22
- 235000013343 vitamin Nutrition 0.000 claims abstract description 22
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 11
- 241000234435 Lilium Species 0.000 claims abstract description 9
- 238000007873 sieving Methods 0.000 claims abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 32
- 230000035622 drinking Effects 0.000 claims description 29
- 235000008216 herbs Nutrition 0.000 claims description 29
- 230000010354 integration Effects 0.000 claims description 29
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 20
- 235000012054 meals Nutrition 0.000 claims description 18
- 239000011573 trace mineral Substances 0.000 claims description 16
- 235000013619 trace mineral Nutrition 0.000 claims description 16
- 229920001503 Glucan Polymers 0.000 claims description 15
- 235000011347 Moringa oleifera Nutrition 0.000 claims description 15
- TWNIBLMWSKIRAT-VFUOTHLCSA-N levoglucosan Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@H]2CO[C@@H]1O2 TWNIBLMWSKIRAT-VFUOTHLCSA-N 0.000 claims description 13
- -1 phytosterol Chemical compound 0.000 claims description 13
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 10
- 244000241838 Lycium barbarum Species 0.000 claims description 10
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 9
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 9
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 9
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 9
- 235000008708 Morus alba Nutrition 0.000 claims description 9
- 240000000249 Morus alba Species 0.000 claims description 9
- 244000046146 Pueraria lobata Species 0.000 claims description 9
- 235000010575 Pueraria lobata Nutrition 0.000 claims description 9
- 210000000582 semen Anatomy 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 239000003094 microcapsule Substances 0.000 claims description 8
- 235000006753 Platycodon grandiflorum Nutrition 0.000 claims description 7
- 240000003582 Platycodon grandiflorus Species 0.000 claims description 7
- 239000002253 acid Substances 0.000 claims description 6
- 150000001413 amino acids Chemical class 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 5
- 125000001931 aliphatic group Chemical group 0.000 claims description 4
- 235000021281 monounsaturated fatty acids Nutrition 0.000 claims description 3
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 claims description 2
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 claims description 2
- 229920002307 Dextran Polymers 0.000 claims description 2
- 241000208688 Eucommia Species 0.000 claims description 2
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims description 2
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 claims description 2
- 101710093543 Probable non-specific lipid-transfer protein Proteins 0.000 claims description 2
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims description 2
- 235000010081 allicin Nutrition 0.000 claims description 2
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 claims description 2
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 claims description 2
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims description 2
- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 claims description 2
- 235000020243 first infant milk formula Nutrition 0.000 claims description 2
- 229930003944 flavone Natural products 0.000 claims description 2
- 150000002213 flavones Chemical class 0.000 claims description 2
- 235000011949 flavones Nutrition 0.000 claims description 2
- 229960003692 gamma aminobutyric acid Drugs 0.000 claims description 2
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims description 2
- 229960002442 glucosamine Drugs 0.000 claims description 2
- 235000012680 lutein Nutrition 0.000 claims description 2
- 229960005375 lutein Drugs 0.000 claims description 2
- 239000001656 lutein Substances 0.000 claims description 2
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims description 2
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 claims description 2
- 235000012661 lycopene Nutrition 0.000 claims description 2
- 229960004999 lycopene Drugs 0.000 claims description 2
- 239000001751 lycopene Substances 0.000 claims description 2
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 claims description 2
- 235000021283 resveratrol Nutrition 0.000 claims description 2
- 229940016667 resveratrol Drugs 0.000 claims description 2
- 150000004671 saturated fatty acids Chemical class 0.000 claims description 2
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 claims description 2
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims description 2
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 claims description 2
- 244000179886 Moringa oleifera Species 0.000 claims 3
- 239000000843 powder Substances 0.000 abstract description 96
- 239000008280 blood Substances 0.000 abstract description 36
- 210000004369 blood Anatomy 0.000 abstract description 36
- 239000008103 glucose Substances 0.000 abstract description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 13
- 238000011161 development Methods 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 210000003754 fetus Anatomy 0.000 abstract description 6
- 235000005911 diet Nutrition 0.000 abstract description 5
- 239000004519 grease Substances 0.000 abstract description 5
- 230000000378 dietary effect Effects 0.000 abstract description 3
- 235000004879 dioscorea Nutrition 0.000 abstract description 2
- 238000005516 engineering process Methods 0.000 abstract description 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 235000007215 black sesame Nutrition 0.000 abstract 1
- 230000029087 digestion Effects 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 description 26
- 244000068988 Glycine max Species 0.000 description 25
- 239000000839 emulsion Substances 0.000 description 24
- 235000019197 fats Nutrition 0.000 description 23
- 235000013350 formula milk Nutrition 0.000 description 21
- 235000018102 proteins Nutrition 0.000 description 20
- 235000000346 sugar Nutrition 0.000 description 20
- 239000003921 oil Substances 0.000 description 18
- 235000019198 oils Nutrition 0.000 description 18
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 16
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 16
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 16
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 16
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 16
- 239000000835 fiber Substances 0.000 description 15
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 14
- 229920002774 Maltodextrin Polymers 0.000 description 13
- 239000005913 Maltodextrin Substances 0.000 description 13
- 229940035034 maltodextrin Drugs 0.000 description 13
- 241000220215 Moringa Species 0.000 description 12
- 235000009811 Momordica charantia Nutrition 0.000 description 11
- 235000009812 Momordica cochinchinensis Nutrition 0.000 description 11
- 240000001740 Momordica dioica Species 0.000 description 11
- 235000018365 Momordica dioica Nutrition 0.000 description 11
- 206010012601 diabetes mellitus Diseases 0.000 description 11
- 241000251468 Actinopterygii Species 0.000 description 10
- 241000699666 Mus <mouse, genus> Species 0.000 description 10
- 229920000294 Resistant starch Polymers 0.000 description 10
- 235000019688 fish Nutrition 0.000 description 10
- 239000004006 olive oil Substances 0.000 description 10
- 235000008390 olive oil Nutrition 0.000 description 10
- 235000021254 resistant starch Nutrition 0.000 description 10
- 102000015636 Oligopeptides Human genes 0.000 description 9
- 108010038807 Oligopeptides Proteins 0.000 description 9
- 235000014633 carbohydrates Nutrition 0.000 description 9
- 235000013312 flour Nutrition 0.000 description 9
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 8
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 8
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 8
- 229920000858 Cyclodextrin Polymers 0.000 description 8
- 239000004375 Dextrin Substances 0.000 description 8
- 229920001353 Dextrin Polymers 0.000 description 8
- 229920001202 Inulin Polymers 0.000 description 8
- 240000003183 Manihot esculenta Species 0.000 description 8
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 description 8
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 8
- 235000004347 Perilla Nutrition 0.000 description 8
- 244000124853 Perilla frutescens Species 0.000 description 8
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 8
- 239000005862 Whey Substances 0.000 description 8
- 108010046377 Whey Proteins Proteins 0.000 description 8
- 102000007544 Whey Proteins Human genes 0.000 description 8
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 8
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 8
- 235000013734 beta-carotene Nutrition 0.000 description 8
- 239000011648 beta-carotene Substances 0.000 description 8
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 8
- 229960002747 betacarotene Drugs 0.000 description 8
- 239000011575 calcium Substances 0.000 description 8
- 229960005069 calcium Drugs 0.000 description 8
- 229910052791 calcium Inorganic materials 0.000 description 8
- 235000001465 calcium Nutrition 0.000 description 8
- 239000003240 coconut oil Substances 0.000 description 8
- 235000019864 coconut oil Nutrition 0.000 description 8
- 235000021277 colostrum Nutrition 0.000 description 8
- 210000003022 colostrum Anatomy 0.000 description 8
- 235000019425 dextrin Nutrition 0.000 description 8
- 229960000304 folic acid Drugs 0.000 description 8
- 235000019152 folic acid Nutrition 0.000 description 8
- 239000011724 folic acid Substances 0.000 description 8
- 235000021255 galacto-oligosaccharides Nutrition 0.000 description 8
- 150000003271 galactooligosaccharides Chemical class 0.000 description 8
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 8
- 229940029339 inulin Drugs 0.000 description 8
- 229910052742 iron Inorganic materials 0.000 description 8
- 229960003512 nicotinic acid Drugs 0.000 description 8
- 235000001968 nicotinic acid Nutrition 0.000 description 8
- 239000011664 nicotinic acid Substances 0.000 description 8
- 229940055726 pantothenic acid Drugs 0.000 description 8
- 235000019161 pantothenic acid Nutrition 0.000 description 8
- 239000011713 pantothenic acid Substances 0.000 description 8
- 108090000765 processed proteins & peptides Proteins 0.000 description 8
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 8
- 239000003549 soybean oil Substances 0.000 description 8
- 235000012424 soybean oil Nutrition 0.000 description 8
- 229960003080 taurine Drugs 0.000 description 8
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 8
- 235000019155 vitamin A Nutrition 0.000 description 8
- 239000011719 vitamin A Substances 0.000 description 8
- 239000011716 vitamin B2 Substances 0.000 description 8
- 239000011726 vitamin B6 Substances 0.000 description 8
- 229940045997 vitamin a Drugs 0.000 description 8
- 235000008939 whole milk Nutrition 0.000 description 8
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 8
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 7
- 102000008186 Collagen Human genes 0.000 description 7
- 108010035532 Collagen Proteins 0.000 description 7
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 7
- 229920002752 Konjac Polymers 0.000 description 7
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 7
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 7
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 7
- 229930003270 Vitamin B Natural products 0.000 description 7
- 229930003268 Vitamin C Natural products 0.000 description 7
- 229930003316 Vitamin D Natural products 0.000 description 7
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 7
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 7
- 229920001436 collagen Polymers 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 239000003292 glue Substances 0.000 description 7
- 230000007062 hydrolysis Effects 0.000 description 7
- 238000006460 hydrolysis reaction Methods 0.000 description 7
- 230000002218 hypoglycaemic effect Effects 0.000 description 7
- 239000011630 iodine Substances 0.000 description 7
- 229910052740 iodine Inorganic materials 0.000 description 7
- 239000011777 magnesium Substances 0.000 description 7
- 229910052749 magnesium Inorganic materials 0.000 description 7
- 229940091250 magnesium supplement Drugs 0.000 description 7
- 239000011574 phosphorus Substances 0.000 description 7
- 229910052698 phosphorus Inorganic materials 0.000 description 7
- 239000011591 potassium Substances 0.000 description 7
- 229910052700 potassium Inorganic materials 0.000 description 7
- 239000011734 sodium Substances 0.000 description 7
- 229910052708 sodium Inorganic materials 0.000 description 7
- 235000019156 vitamin B Nutrition 0.000 description 7
- 239000011720 vitamin B Substances 0.000 description 7
- 235000019154 vitamin C Nutrition 0.000 description 7
- 239000011718 vitamin C Substances 0.000 description 7
- 235000019166 vitamin D Nutrition 0.000 description 7
- 239000011710 vitamin D Substances 0.000 description 7
- 150000003710 vitamin D derivatives Chemical class 0.000 description 7
- 229940046008 vitamin d Drugs 0.000 description 7
- 239000011701 zinc Substances 0.000 description 7
- 229910052725 zinc Inorganic materials 0.000 description 7
- 229930006000 Sucrose Natural products 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- 239000005720 sucrose Substances 0.000 description 6
- 235000001014 amino acid Nutrition 0.000 description 5
- 230000001804 emulsifying effect Effects 0.000 description 5
- 150000002632 lipids Chemical class 0.000 description 5
- 230000035935 pregnancy Effects 0.000 description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 235000014113 dietary fatty acids Nutrition 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- 239000000194 fatty acid Substances 0.000 description 4
- 229930195729 fatty acid Natural products 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000011785 micronutrient Substances 0.000 description 4
- 235000013369 micronutrients Nutrition 0.000 description 4
- 238000004806 packaging method and process Methods 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 241000675108 Citrus tangerina Species 0.000 description 3
- 206010018473 Glycosuria Diseases 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 3
- 244000046052 Phaseolus vulgaris Species 0.000 description 3
- 240000008042 Zea mays Species 0.000 description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 3
- 238000013019 agitation Methods 0.000 description 3
- 235000013339 cereals Nutrition 0.000 description 3
- 235000005822 corn Nutrition 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 238000011121 vaginal smear Methods 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 2
- 235000000832 Ayote Nutrition 0.000 description 2
- 244000077995 Coix lacryma jobi Species 0.000 description 2
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 2
- 240000004244 Cucurbita moschata Species 0.000 description 2
- 235000009854 Cucurbita moschata Nutrition 0.000 description 2
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 description 2
- 235000009419 Fagopyrum esculentum Nutrition 0.000 description 2
- 240000008620 Fagopyrum esculentum Species 0.000 description 2
- 229930091371 Fructose Natural products 0.000 description 2
- 239000005715 Fructose Substances 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 240000002853 Nelumbo nucifera Species 0.000 description 2
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 2
- 235000002595 Solanum tuberosum Nutrition 0.000 description 2
- 244000061456 Solanum tuberosum Species 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- ZSJLQEPLLKMAKR-UHFFFAOYSA-N Streptozotocin Natural products O=NN(C)C(=O)NC1C(O)OC(CO)C(O)C1O ZSJLQEPLLKMAKR-UHFFFAOYSA-N 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 244000098338 Triticum aestivum Species 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 239000010495 camellia oil Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000020805 dietary restrictions Nutrition 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 239000011261 inert gas Substances 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 239000000787 lecithin Substances 0.000 description 2
- 235000010445 lecithin Nutrition 0.000 description 2
- 229940067606 lecithin Drugs 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 235000021590 normal diet Nutrition 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 2
- 235000013594 poultry meat Nutrition 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 235000015136 pumpkin Nutrition 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 2
- 229960001052 streptozocin Drugs 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 239000011715 vitamin B12 Substances 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 1
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 description 1
- WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 description 1
- 241000143060 Americamysis bahia Species 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 241000972773 Aulopiformes Species 0.000 description 1
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 241000167854 Bourreria succulenta Species 0.000 description 1
- 235000011299 Brassica oleracea var botrytis Nutrition 0.000 description 1
- 235000017647 Brassica oleracea var italica Nutrition 0.000 description 1
- 240000003259 Brassica oleracea var. botrytis Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 241001107116 Castanospermum australe Species 0.000 description 1
- 241000206575 Chondrus crispus Species 0.000 description 1
- 244000205754 Colocasia esculenta Species 0.000 description 1
- 235000006481 Colocasia esculenta Nutrition 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000371652 Curvularia clavata Species 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 244000000626 Daucus carota Species 0.000 description 1
- 235000002767 Daucus carota Nutrition 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 240000001008 Dimocarpus longan Species 0.000 description 1
- 240000005717 Dioscorea alata Species 0.000 description 1
- 235000000235 Euphoria longan Nutrition 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 208000035223 Gestational Weight Gain Diseases 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 description 1
- 206010022489 Insulin Resistance Diseases 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000005717 Laminarin Substances 0.000 description 1
- 229920001543 Laminarin Polymers 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 240000004713 Pisum sativum Species 0.000 description 1
- 235000010582 Pisum sativum Nutrition 0.000 description 1
- 241001300674 Plukenetia volubilis Species 0.000 description 1
- 101710089165 Protein white Proteins 0.000 description 1
- 241000382353 Pupa Species 0.000 description 1
- 241000287420 Pyrus x nivalis Species 0.000 description 1
- 244000088415 Raphanus sativus Species 0.000 description 1
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 241001482311 Trionychidae Species 0.000 description 1
- 235000011453 Vigna umbellata Nutrition 0.000 description 1
- 240000001417 Vigna umbellata Species 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003779 Vitamin B12 Natural products 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 235000019498 Walnut oil Nutrition 0.000 description 1
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 description 1
- FRYDSOYOHWGSMD-UHFFFAOYSA-N [C].O Chemical compound [C].O FRYDSOYOHWGSMD-UHFFFAOYSA-N 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 235000021279 black bean Nutrition 0.000 description 1
- 235000014121 butter Nutrition 0.000 description 1
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical group [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 description 1
- 239000001354 calcium citrate Substances 0.000 description 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 1
- MKJXYGKVIBWPFZ-CEOVSRFSSA-L calcium;(2s)-2-hydroxypropanoate Chemical compound [Ca+2].C[C@H](O)C([O-])=O.C[C@H](O)C([O-])=O MKJXYGKVIBWPFZ-CEOVSRFSSA-L 0.000 description 1
- 235000019577 caloric intake Nutrition 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000021074 carbohydrate intake Nutrition 0.000 description 1
- 230000023852 carbohydrate metabolic process Effects 0.000 description 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- GRWVQDDAKZFPFI-UHFFFAOYSA-H chromium(III) sulfate Chemical compound [Cr+3].[Cr+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRWVQDDAKZFPFI-UHFFFAOYSA-H 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000019700 dicalcium phosphate Nutrition 0.000 description 1
- 235000008242 dietary patterns Nutrition 0.000 description 1
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000004222 ferrous gluconate Substances 0.000 description 1
- 235000013924 ferrous gluconate Nutrition 0.000 description 1
- 229960001645 ferrous gluconate Drugs 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- BJHIKXHVCXFQLS-UYFOZJQFSA-N fructose group Chemical group OCC(=O)[C@@H](O)[C@H](O)[C@H](O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 230000002641 glycemic effect Effects 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 235000009200 high fat diet Nutrition 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- VRIVJOXICYMTAG-IYEMJOQQSA-L iron(ii) gluconate Chemical group [Fe+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O VRIVJOXICYMTAG-IYEMJOQQSA-L 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000005772 leucine Nutrition 0.000 description 1
- 150000002614 leucines Chemical class 0.000 description 1
- 239000001755 magnesium gluconate Substances 0.000 description 1
- 235000015778 magnesium gluconate Nutrition 0.000 description 1
- 229960003035 magnesium gluconate Drugs 0.000 description 1
- IAKLPCRFBAZVRW-XRDLMGPZSA-L magnesium;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate;hydrate Chemical compound O.[Mg+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O IAKLPCRFBAZVRW-XRDLMGPZSA-L 0.000 description 1
- 239000011683 manganese gluconate Substances 0.000 description 1
- 235000014012 manganese gluconate Nutrition 0.000 description 1
- 229940072543 manganese gluconate Drugs 0.000 description 1
- OXHQNTSSPHKCPB-IYEMJOQQSA-L manganese(2+);(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Mn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O OXHQNTSSPHKCPB-IYEMJOQQSA-L 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 238000007410 oral glucose tolerance test Methods 0.000 description 1
- GSSMIHQEWAQUPM-AOLPDKKJSA-N ovalbumin peptide Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C1=CN=CN1 GSSMIHQEWAQUPM-AOLPDKKJSA-N 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 230000000291 postprandial effect Effects 0.000 description 1
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Substances [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 description 1
- 235000013406 prebiotics Nutrition 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000011684 sodium molybdate Substances 0.000 description 1
- 235000015393 sodium molybdate Nutrition 0.000 description 1
- TVXXNOYZHKPKGW-UHFFFAOYSA-N sodium molybdate (anhydrous) Chemical compound [Na+].[Na+].[O-][Mo]([O-])(=O)=O TVXXNOYZHKPKGW-UHFFFAOYSA-N 0.000 description 1
- 239000011781 sodium selenite Substances 0.000 description 1
- 235000015921 sodium selenite Nutrition 0.000 description 1
- 229960001471 sodium selenite Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 230000037351 starvation Effects 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 235000021147 sweet food Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 235000014393 valine Nutrition 0.000 description 1
- 150000003680 valines Chemical class 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000008170 walnut oil Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000011670 zinc gluconate Substances 0.000 description 1
- 235000011478 zinc gluconate Nutrition 0.000 description 1
- 229960000306 zinc gluconate Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention relates to a special clinical nutrient composition for gestational diabetes and a preparation method of the nutrient composition. The composition comprises 20-35 parts of protein, 8-15 parts of fat, 25-40 parts of carbohydrate, 3-8 parts of dietary fiber, 0.6-1.2 parts of macroelements, 0.01-0.03 parts of microelements, 0.005-0.015 parts of fat-soluble vitamins, 0.08-0.2 parts of water-soluble vitamins, 0.05-0.6 parts of dietary essence, 0.5-4 parts of medicinal and edible components, 0.1-1 part of natural plant compounds and 0.1-0.4 parts of new resource food, wherein the medicinal and edible components are selected from at least one of Chinese yams, black sesame, radix puerariae, rhizoma polygonate, folium mori, fructus lycii, radix platycodonis and lilies; powder is prepared from the components in advance, and grease powder is prepared from fat with a microencapsulating technology. Through sieving and proportioning of the components, the nutrient composition can provide comprehensive nutrition for patients suffering from gestational diabetes, and digestion and absorption are facilitated; besides, the components with the blood glucose reducing function are added to assist in reducing the blood glucose level of the gestational diabetes and the disease risk, and growth demands and normal development of fetuses are guaranteed.
Description
Technical field
The present invention relates to special medicine purposes formula food field, and in particular to a kind of clinical battalion of gestational diabetes mellitus tailored version
Support formula and preparation method thereof.
Background technology
Gestational diabetes mellitus (GDM) refers to generation first or the abnormal carbohydrate metabolism for finding between the pregnancy period.The diagnosis of current GDM according to
According to the standard that international gestational diabetes mellitus expert group (IADPSG) proposed in 2010, i.e., according to 75g oral glucose tolerance tests
(OGTY) result：Fasting blood-glucose (FBG) and after the meal 1, the blood glucose value of 2h should be respectively lower than 5.1,10.0,8.5mmol/L.It is any
Item blood glucose value meets or exceeds above-mentioned standard and is diagnosed as GDM.According to above diagnostic criteria, foreign countries' report GDM incidences of disease are
9.8%~25.5%, China GDM incidence of disease are 9.3%~17.1%.
With the raising of economic level, bad life style, such as high heat, high fat diet, lack the originals such as motion at sitting
Cause so that the gestational diabetes mellitus incidence of disease is in ascendant trend year by year.Epidemiological study has confirmed, rich in sweet food, higher fatty acid food
The eating pattern of thing is the dietary risk factors of GDM morbidities.
Gestational diabetes mellitus is obstetrics' common disease, pregnant and lying-in women can be made to increase with the illness rate and case fatality rate of fetus, serious shadow
Ring the health of mother and baby；And have long-range influence on patient and filial generation, the generation of diabetes B in 20 years patients with gestational diabetes postpartum
Rate is up to 40%, and the danger that filial generation occurs fat, diabetes is also greatly increased.Therefore the state that the research to gestational diabetes mellitus is subject to
Inside and outside great attention.
Dietary therapy, foreign countries are commonly referred to medical nutrient treatment (MNT), are to control blood sugar, reduction gestational diabetes mellitus bad
One of important measures of influence, the glycemic control the purpose is to make GDM patient ensures the nutrition of pregnant woman and fetus in normal level
Intake, reduces female youngster's complication.Research both at home and abroad shows that most of GDM patients can obtain by blood sugar after MNT and appropriate exercise
To good control.Wherein control gross energy intake, monitoring carbohydrate intake are the Key Strategies for controlling blood sugar.
And often found in clinical position, some patients fear the adverse consequences that blood glucose rise causes, often uncomplaisance,
Excessively keep on a diet, hardly realizing that excessive dietary restriction is equally possible causes Averse pregnancy outcomes.Excessive dietary restriction, especially greatly
Amount reduces staple food intake, can cause starvation, induces ketoboidies and produces.There is the heat of scholar's intake per Et to GDM groups and Normal group
Amount is analyzed, and carries out blood SA detection in pregnant 25-37 week, as a result shows the fewer ketoboidies water of heat of GDM groups intake
It is flat higher, and producing for ketoboidies can produce harmful effect to the intelligence development of fetus and behavior development.Maternal weight gain is bad simultaneously
To also the growth and development of normal fetal be influenceed, then cause FGR, low birth body mass infant occur.
Gestational diabetes mellitus can cause various serious harm, therefore develop the various nutrition needed for can providing pregnant and lying-in women
Product that is plain and can steadily reducing pregnant and lying-in women's blood sugar, to ensureing that baby's health and safety have important value and meaning.However, mesh
The formula of preceding external product (Abbott Laboratories, Fei Senyoushika ratios), is only capable of providing effective nutritional support, without integration of drinking and medicinal herbs or new resources
Composition, itself is without function of blood sugar reduction；And it is domestic only have a few studies, with the addition of part have function of blood sugar reduction integration of drinking and medicinal herbs or
New resources composition, but the support of its nutrient, especially essential trace element is inadequate.
Chinese patent CN106173826A discloses a kind of nutrient powder for treating gestational diabetes, and its component includes Hu trailing plants
The Vegetable powder that fore-telling, mushroom, balsam pear, lotus root, pumpkin and black fungus are made, coarse cereal powder that chestnut, buckwheat, pea and the seed of Job's tears are made and
The traditional Chinese medicine powder that matrimony vine, corn stigma, peanut coat and Radix et Rhizoma Gynurae divaricatae are made, although it can effectively reduce the blood sugar of patients with gestational diabetes
Value, but itself and be not added with protein, fat, trace element, new resource food etc., this causes comprehensively meet glycosuria gravidarum
The daily energy requirement and nutritional need of patient, while can also influence the normal development of fetus.
The content of the invention
It is an object of the invention to overcome defect of the prior art, there is provided a kind of gestational diabetes mellitus tailored version clinical nutrition
Formula and preparation method thereof, gestational diabetes mellitus tailored version clinical nutrition formula of the present invention is provided for patients with gestational diabetes
Comprehensively, efficient nutritional support.Lack the support of micronutrient element for studies in China, with the addition of required micronutrient unit
Element, necessary to such micronutrient element is baby's health；And for defect of the external product without integration of drinking and medicinal herbs composition, pass through
Integration of drinking and medicinal herbs composition of the addition with effect of lowering blood sugar, natural plants compound and new resource food, auxiliary reduce glycosuria gravidarum
The blood glucose value of disease, reduces the risk of gestational diabetes mellitus.
To achieve the above object, the present invention is adopted the following technical scheme that：
On the one hand, the present invention provides a kind of gestational diabetes mellitus tailored version clinical nutrition and is formulated, including following parts by weight
Component：20-35 parts of protein, 8-15 parts of fat, 25-40 parts of carbohydrate, 3-8 parts of dietary fiber, 0.6-1.2 parts of constant unit
Element, 0.01-0.03 parts of trace element, 0.005-0.015 parts of liposoluble vitamin, 0.08-0.2 parts of water soluble vitamin, 0.05-
0.6 part of meals elite, 0.5-4 parts of integration of drinking and medicinal herbs composition, 0.1-1 parts of natural plants compound and 0.1-0.4 portions of new resources food
Product.
In order to further optimize above-mentioned technical proposal, the technical measures that the present invention is taken also include：
Preferably, the protein is selected from PURE WHEY, soybean protein isolate, whole milk powder, dried whole-egg, newborn iron egg
In vain, at least one in colostrum, amino acid, protein peptides；
Wherein, the amino acid is selected from 1B-Pidolidone, the glutamic acid of L mono-, the arginine of L mono-, L-Trp, L mono-
At least one in glutamine, taurine, the valines of L mono-, ILE, the leucines of L mono-；The protein peptides are selected from soybean
In oligopeptide, wheat protein peptide, pupa albumen peptide, ocean fish oligopeptide powder, laughable peptide, amino peptide, ovalbumin peptide at least
It is a kind of.
Preferably, the fat includes saturated fatty acid, polyunsaturated fatty acid, monounsaturated fatty acids, OPO structures
At least one in fat, DHA, EPA, ARA, phosphatide, more specifically it is described fat include safflower seed oil, walnut oil, peanut oil,
Soybean oil, Ah's glycerine, olive oil, tea oil, oil and fat of sacha inchi, olive oil, coconut oil, perilla herb oil, deep sea fish oil, cupu oil, palm
Oil, butter, cream, lard, medium chain triglyceride, lecithin.
Preferably, the carbohydrate is including in fructose, rock sugar, lactose, maltodextrin, tapioca, resistant starch
At least two.
Preferably, the dietary fiber comprising inulin, konjaku flour, galactooligosaccharide, FOS, oligoisomaltose,
At least one in soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya.
Preferably, the macroelement is selected from calcium citrate, L-calcium lactate, calcium monohydrogen phosphate, K-IAO, sodium citrate
With at least one in magnesium gluconate.
Preferably, the trace element is selected from ferrous gluconate, KI, zinc gluconate, sodium selenite, glucose
At least one in sour copper, chromium sulfate, manganese gluconate and sodium molybdate.
Preferably, the liposoluble vitamin is selected from vitamin A, beta carotene, vitamine D3, vitamin E, vitamin
At least one in K1.
Preferably, the water soluble vitamin is selected from vitamin B1, vitamin B2, vitamin B6, vitamin B12, dimension life
At least one in plain C, pantothenic acid, folic acid, nicotinic acid, choline, inositol, biotin.
Preferably, the meals elite is selected from cereal, beans, potato class, greengrocery, Homonemeae, nut-seed class, fishes and shrimps
At least one in class, poultry meat, fruits；Wherein described cereal it is main by rice meal, millet powder, black rice flour, coixlacrymajobi powder,
One kind in corn flour, wheat germ powder, oatmeal, buckwheat or at least two compositions, the beans it is main by peameal, it is green
One kind or at least two compositions in bean powder, black bean powder, red bean powder, soy meal, the potato class are mainly made up of common yam rhizome powder, described
Vegetable powder is main by one kind in carrot meal, white radish powder, pumpkin powder, spinach powder, tomato meal, broccoli powder, balsam pear powder or several
Composition is planted, the Homonemeae is main by one or more in mushroom powder and white fungus powder, and the nut-seed class is mainly lotus seeds
Powder, the fish and shrimp are mainly and are made up of one or more in salmon powder and cod meal, the poultry meat be mainly by
One or more compositions in chicken meal, powdered beef, the fruits it is main by red date powder, longan powder, apple powder, cherry powder,
One or more compositions in oranges and tangerines powder, pyrus nivalis powder；The meals elite is more preferably balsam pear powder.
Preferably, the integration of drinking and medicinal herbs composition is selected from Chinese yam, Semen sesami nigrum, the root of kudzu vine, sealwort, mulberry leaf, matrimony vine, balloonflower root, lily
In at least one.
Preferably, the natural plants compound is selected from l-cn, Glucosamine, FOS, lutein, plant
At least one in sterol, lycopene, resveratrol, allicin；The natural plants compound is more preferably l-cn.
Preferably, the new resource food is selected from first milk basic protein, GABA, chitosan oligosaccharide, eucommia Bark male flower, bamboo
At least one in leaf flavones, CPP, avenabeta glucosan, yeast beta-dextran, leaf of Moringa, xylo-oligosaccharide；Institute
New resource food more preferably leaf of Moringa and avenabeta glucosan are stated, wherein the weight portion of the leaf of Moringa and avenabeta glucosan
Number is than being 1:1.
Preferably, the parts by weight of each component are as follows in the integration of drinking and medicinal herbs composition：Chinese yam 0-1 parts, Semen sesami nigrum 0-1 parts,
Root of kudzu vine 0-1 parts, sealwort 0-1 parts, mulberry leaf 0-1 parts, matrimony vine 0-1 parts, balloonflower root 0-1 parts, lily 0-1 parts.
Preferably, the good protein weight provided in the protein and amino acid accounts for the 70% of gross protein weight
More than.
Preferably, the ratio of n-6 aliphatic acid and n-3 aliphatic acid is 3~4 in the fat:1.
On the other hand, the present invention relates to a kind of product prepared by above-mentioned gestational diabetes mellitus tailored version clinical nutrition formula,
Including nutrient powder, nutrition emulsion, capsule, tablet, pill, oral liquid etc..
Finally, the present invention is also provided and a kind of the gestational diabetes mellitus tailored version clinical nutrition formula is prepared into nutrient powder
Method, it comprises the following steps：By the protein of predetermined weight number, fat, carbohydrate, dietary fiber, macroelement,
Trace element, liposoluble vitamin, water soluble vitamin, meals elite, integration of drinking and medicinal herbs composition, natural plants compound and new
Resource food is prepared into the powdery that particle diameter is 100~300 μm respectively, and the powdery is well mixed, and obtains gestational diabetes mellitus special
Use type complete nourishing powder, in packaging bag or pail pack is placed directly within by filling after sterilization processing；
Wherein, it is described fat using micro-capsule embedding techniques be made it is powdered, the integration of drinking and medicinal herbs composition by crush, mistake
60-80 mesh sieves are made powdered.
The present invention also provides a kind of side that the gestational diabetes mellitus tailored version clinical nutrition formula is prepared into nutrition emulsion
Method, it comprises the following steps：
Step one, by the protein of predetermined weight number, fat, carbohydrate, dietary fiber, macroelement, micro
Element, liposoluble vitamin, water soluble vitamin, meals elite, integration of drinking and medicinal herbs composition, natural plants compound and new resources
Food is prepared into the powdery that particle diameter is 100~300 μm respectively；Wherein, it is described fat using micro-capsule embedding techniques be made it is powdered,
The integration of drinking and medicinal herbs composition is made up powdered of crushing, excessively 60-80 mesh sieves；
Step 2, protein powder is dissolved in a certain amount of water fully aquation, obtains protein aqueous solution, then by carbon
Hydrate powder, macroelement powder, micro- powder, water soluble vitamin powder are dissolved in protein aqueous solution,
Obtain aqueous phase solution；
Step 3, by the fat powder after micro-capsule embedding treatment, liposoluble vitamin powder, meals elite powder, medicine food
Homologous component powders, natural plants compound powder sequentially add the aqueous phase solution of gained in step 2, and carry out strong agitation,
Addition emulsifying agent and thickener, obtain concentrated emulsions；
Step 4, in the concentrated emulsions described in step 3 add scheduled volume water and stir, while removing skim-coat
Foam, obtains emulsion, then by emulsion homogeneous under high pressure, in high-temperature sterilization, is cooled to room temperature, and nutrition emulsion is obtained, and will
Nutrition emulsion is filling in packaging bag.
In above two preparation method, the specific implementation step of micro-capsule embedding techniques is as follows：By fat, emulsifying agent, wall
Material prepares emulsion with water mixed dissolution；After by the stirring mixing of above-mentioned emulsion, emulsifying homogeneous treatment is carried out, then sprayed
Dry, screening prepares powdered oil, and powdered oil compares with conventional grease, its dispersiveness, water solubility, emulsibility, inoxidizability
All improve a lot；
Wherein, the emulsifying agent is selected from fatty acid glyceride (glyceride), methyl glycol fatty acid ester (propylene glycol ester), sorb
One or more in glycan fatty acid ester (sorbitan acid), sucrose fatty ester (sucrose ester), lecithin；The wall material choosing
From sodium carboxymethylcellulose, gelatin, carragheen, xanthans, Arabic gum, guar gum, maltodextrin, lipoprotein, corn syrup
In one or more.
Compared with prior art, the invention has the advantages that：
(1) carbohydrate main source is fructose, resistant starch etc., and resistant starch is slow release starch with dietary fiber
Class material, the position that each slow release starch class material is digested and assimilated in enteron aisle is different with the time, is absorbed more compared with ordinary nutritional agent
Slowly, postprandial blood sugar is relatively more steady；The content of monounsaturated fatty acids and polyunsaturated fatty acid is added and adjusted simultaneously,
The energy supply ratio of fat brings up to 45%.Unrighted acid has reduces blood sugar and cholesterol, adjusts blood lipid level, prevents artery
Hardening, reduces the effect such as insulin resistance.
(2) present invention in add balsam pear powder, balsam pear is described as " glucokinin ", and nature and flavor sweetness and bitterness is cold and cool, can heat-clearing, remove
It is tired of, quenches the thirst.Polypeptide, saponins material contained by balsam pear play the role of it is significant hypoglycemic, and to euglycemia without shadow
Ring；Can prevent and improve the complication of diabetes, with regulation blood fat, the effect of enhance immunity.
(3) addition has the integration of drinking and medicinal herbs composition of blood sugar reducing function simultaneously in the present invention, between each component, scientific compatibility, association
Same-action, can play a part of to reduce blood sugar well.
(4) leaf of Moringa and avenabeta glucosan are added in new resource food, wherein leaf of Moringa has reduces blood sugar, reduces blood
Fat, anti-oxidant, antitumor etc. are acted on；Avenabeta glucosan has enhance immunity, reduces cholesterol, hypoglycemic, anticancer, improvement
The effect of enteron aisle state.
(5) present invention prepares powdered oil using micro-capsule embedding techniques so that powdered oil has preferable mobility, easily
It is well mixed in other powdered components；And using after micro-capsule embedding techniques, grease is embedded in wall material, so as to avoid with
The contact of air is to strengthen inoxidizability, so as to the maximum effect of health grease can be played.
(6) raw material of gestational diabetes mellitus tailored version clinical nutrition formula of the present invention is made in advance in preparation process
For into 100~300 μm of powder, this is caused when finished product is prepared, and each nutrition composition can be well mixed, it is ensured that in unit volume
Each nutrition composition content it is identical, while when liquid type preparation is prepared, each nutrition composition can be fully dispersed and be completely dissolved
Into solvent, prevent solids of sedimentation occur in liquid, effect of finished product product has been effectively ensured.
Specific embodiment
The present invention provides a kind of gestational diabetes mellitus tailored version with suppression blood glucose rise for patients with gestational diabetes
Enteral clinical nutrition be formulated, including following parts by weight component：20-35 parts of protein, 8-15 parts of fat, 25-40 parts of carbon water
Compound, 3-8 part dietary fiber, 0.6-1.2 parts of macroelement, 0.01-0.03 parts of trace element, 0.005-0.015 parts of liposoluble
Property vitamin, 0.08-0.2 parts of water soluble vitamin, 0.05-0.6 parts of meals elite, 0.5-4 parts of integration of drinking and medicinal herbs composition, 0.1-1
Part natural plants compound and 0.1-0.4 parts of new resource food.
With reference to embodiment, specific embodiment of the invention is further described.Following examples are only used for more
Plus technical scheme is clearly demonstrated, and can not be limited the scope of the invention with this.
Embodiment 1
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes PURE WHEY 8.3g, soybean separation protein
White 6.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine 0.11g,
Ocean fish oligopeptide powder 0.266g；Olive oil 5.77g, soybean oil 2.48g, coconut oil 1.77g, perilla herb oil 0.64g, medium chain triglyceride
Three ester 0.213g；Maltodextrin 9.28g, tapioca 10g, resistant starch 13.33g；Dietary fiber be selected from inulin, konjaku flour,
In galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya at least one
Kind, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；Calcium in macroelement
0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc 0.007g in trace element；
Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, vitamin E
0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, vitamin B12
0.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Balsam pear powder 0.5g；Medicine is eaten
With Chinese yam 0.3g, Semen sesami nigrum 0.3g, root of kudzu vine 0.3g, sealwort 0.3g, mulberry leaf 0.5g, matrimony vine 0.5g, balloonflower root 0.5g, hundred in derived components
Close 0.5g；L-cn 0.636g in natural plants compound；Leaf of Moringa 0.16g, avenabeta glucosan in new resource food
0.16g。
Embodiment 2
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes that PURE WHEY 10.3g, soybean separate
Albumen 4.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine
0.11g, ocean fish oligopeptide powder 0.266g；Olive oil 2.77g, soybean oil 4.48g, coconut oil 2.77g, perilla herb oil 0.64g, in
Chain triglyceride 0.213g；Maltodextrin 4.78g, tapioca 13g, resistant starch 16.33g；Dietary fiber is selected from inulin, evil spirit
In taro powder, galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya extremely
Few one kind, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；In macroelement
Calcium 0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc in trace element
0.007g；Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, dimension
Raw element E 0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, dimension
Raw element B120.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Balsam pear powder
0.3g；Chinese yam 0.3g, Semen sesami nigrum 0.3g, the root of kudzu vine 0.3, sealwort 0.3g, mulberry leaf 0.5g, matrimony vine 0.5g, tangerine in integration of drinking and medicinal herbs composition
Stalk 0.5g, lily 0.5g；L-cn 0.636g in natural plants compound；Leaf of Moringa 0.16g, oat β in new resource food-
Glucan 0.16g.
Embodiment 3
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes that PURE WHEY 10.3g, soybean separate
Albumen 4.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine
0.11g, ocean fish oligopeptide powder 0.266g；Olive oil 2.77g, soybean oil 4.48g, coconut oil 2.77g, perilla herb oil 0.64g, in
Chain triglyceride 0.213g；Maltodextrin 10.78g, tapioca 10g, resistant starch 13.33g；Dietary fiber be selected from inulin,
In konjaku flour, galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya
At least one, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；Macroelement
Middle calcium 0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc in trace element
0.007g；Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, dimension
Raw element E 0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, dimension life
Plain B120.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Balsam pear powder
0.1g；Chinese yam 0.166g in integration of drinking and medicinal herbs composition, Semen sesami nigrum 0.166g, root of kudzu vine 0.166g, sealwort 0.166g, mulberry leaf 0.166g,
Matrimony vine 0.166g, balloonflower root 0.166g, lily 0.166g；L-cn 0.636g in natural plants compound；In new resource food
Leaf of Moringa 0.16g, avenabeta glucosan 0.16g.
Embodiment 4
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes that PURE WHEY 10.3g, soybean separate
Albumen 4.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine
0.11g, ocean fish oligopeptide powder 0.266g；Olive oil 2.77g, soybean oil 4.48g, coconut oil 2.77g, perilla herb oil 0.64g, in
Chain triglyceride 0.213g；Maltodextrin 10.78g, tapioca 10g, resistant starch 13.33g；Dietary fiber be selected from inulin,
In konjaku flour, galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya
At least one, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；Macroelement
Middle calcium 0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc in trace element
0.007g；Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, dimension
Raw element E 0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, dimension life
Plain B120.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Balsam pear powder
0.1g；Chinese yam 0.1g, Semen sesami nigrum 0.1g, root of kudzu vine 0.1g, sealwort 0.1g, mulberry leaf 0.1g, matrimony vine 0.1g, tangerine in integration of drinking and medicinal herbs composition
Stalk 0.1g, lily 0.1g；L-cn 0.636g in natural plants compound；Leaf of Moringa 0.1g, oat β in new resource food-
Glucan 0.1g.
Embodiment 5
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes that PURE WHEY 10.3g, soybean separate
Albumen 4.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine
0.11g, ocean fish oligopeptide powder 0.266g；Olive oil 2.77g, soybean oil 4.48g, coconut oil 2.77g, perilla herb oil 0.64g, in
Chain triglyceride 0.213g；Maltodextrin 10.88g, tapioca 10g, resistant starch 13.33g；Dietary fiber be selected from inulin,
In konjaku flour, galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya
At least one, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；Macroelement
Middle calcium 0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc in trace element
0.007g；Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, dimension
Raw element E 0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, dimension life
Plain B120.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Integration of drinking and medicinal herbs into
Chinese yam 0.1g, Semen sesami nigrum 0.1g, root of kudzu vine 0.1g, sealwort 0.1g, mulberry leaf 0.1g, matrimony vine 0.1g, balloonflower root 0.1g, lily in point
0.1g；L-cn 0.636g in natural plants compound；Leaf of Moringa 0.16g, avenabeta glucosan in new resource food
0.16g。
Embodiment 6
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes that PURE WHEY 10.3g, soybean separate
Albumen 4.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine
0.11g, ocean fish oligopeptide powder 0.266g；Olive oil 2.77g, soybean oil 4.48g, coconut oil 2.77g, perilla herb oil 0.64g, in
Chain triglyceride 0.213g；Maltodextrin 11.58g, tapioca 10g, resistant starch 13.33g；Dietary fiber be selected from inulin,
In konjaku flour, galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya
At least one, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；Macroelement
Middle calcium 0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc in trace element
0.007g；Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, dimension
Raw element E 0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, dimension life
Plain B120.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Balsam pear powder
0.1g；L-cn 0.636g in natural plants compound；Leaf of Moringa 0.1g, avenabeta glucosan 0.1g in new resource food.
Embodiment 7
Gestational diabetes mellitus tailored version clinical nutrition formula of the present invention includes that PURE WHEY 10.3g, soybean separate
Albumen 4.33g, hydrolysis Isin glue collagen 0.66g, whole milk powder 12g, dried whole-egg 0.33g, colostrum 0.16g, taurine
0.11g, ocean fish oligopeptide powder 0.266g；Olive oil 2.77g, soybean oil 4.48g, coconut oil 2.77g, perilla herb oil 0.64g, in
Chain triglyceride 0.213g；Maltodextrin 11.68g, tapioca 10g, resistant starch 13.33g；Dietary fiber be selected from inulin,
In konjaku flour, galactooligosaccharide, FOS, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, fibre and soya
At least one, its gross mass is 4.99g, wherein water-soluble dietary fiber 3.83g, insoluble diedairy fiber 1.16g；Macroelement
Middle calcium 0.4g, phosphorus 0.25g, potassium 0.08g, sodium 0.02g, magnesium 0.15g；Iron 0.011g, iodine 0.00014g, zinc in trace element
0.007g；Vitamin A 0.0006g, beta carotene 0.000057g, vitamin D in liposoluble vitamin30.000001g, dimension
Raw element E 0.009g；Vitamin B in water soluble vitamin10.001g, vitamin B20.001g, vitamin B60.001g, dimension life
Plain B120.000002g, vitamin C 0.117g, pantothenic acid 0.003g, folic acid 0.000165g, nicotinic acid 0.0165g；Natural plants
L-cn 0.636g in compound；Leaf of Moringa 0.1g, avenabeta glucosan 0.1g in new resource food.
Embodiment 8
The preparation method of the nutrient powder of the gestational diabetes mellitus tailored version clinical nutrition formula containing embodiment 1- embodiments 7 is such as
Under：
1) powdered oil is prepared：By the fat of predetermined weight with sucrose ester, monoglyceride, maltodextrin, water at 70 DEG C or so
Carry out mixed dissolution and prepare emulsion, the wherein consumption of sucrose ester and monoglyceride is the 2.5%~5% of emulsion weight, water
Consumption is 10~15 times of fat weight, and maltodextrin consumption is the 8%~20% of emulsion weight；By the stirring of above-mentioned emulsion
After 2~5min of mixing, 2 emulsifying homogeneous treatment are carried out under high pressure, the emulsifying homogeneous time is 12~18min；Then sprayed
Mist is dried, and powdered oil is prepared with 60~80 mesh sieves point；
2) integration of drinking and medicinal herbs component powders are prepared：By the integration of drinking and medicinal herbs composition of predetermined weight be put into pulverizer crushed, mistake
60~80 mesh sieves are made integration of drinking and medicinal herbs component powders；
3) by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, trace element, the life of fat-soluble dimension
It is 100~300 that element, water soluble vitamin, meals elite, natural plants compound and new resource food are prepared into particle diameter respectively
μm powdery；
4) by step 1)~step 3) obtained by powder be well mixed, to obtain the full nutrition of gestational diabetes mellitus tailored version
Powder, in sterilized packaging bag or sterilized pail pack is placed directly within by filling after sterilization processing.
Aforesaid operations step is both needed to be carried out under the protection of inert gas, such as nitrogen protection, to prevent that powder is quick-fried
Fried danger.
Embodiment 9
The preparation method of the nutrition emulsion of the gestational diabetes mellitus tailored version clinical nutrition formula containing embodiment 1- embodiments 7
It is as follows：
1) powdered oil is prepared：By the fat of predetermined weight with sucrose ester, monoglyceride, maltodextrin, water at 70 DEG C or so
Carry out mixed dissolution and prepare emulsion, the wherein consumption of sucrose ester and monoglyceride is the 2.5%~5% of emulsion weight, water
Consumption is 10~15 times of fat weight, and maltodextrin consumption is the 8%~20% of emulsion weight；By the stirring of above-mentioned emulsion
After 2~5min of mixing, 2 emulsifying homogeneous treatment are carried out under high pressure, the emulsifying homogeneous time is 12~18min；Then sprayed
Mist is dried, and powdered oil is prepared with 60~80 mesh sieves point；
2) integration of drinking and medicinal herbs component powders are prepared：By the integration of drinking and medicinal herbs composition of predetermined weight be put into pulverizer crushed, mistake
60~80 mesh sieves are made integration of drinking and medicinal herbs component powders；
3) by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, trace element, the life of fat-soluble dimension
It is 100~300 that element, water soluble vitamin, meals elite, natural plants compound and new resource food are prepared into particle diameter respectively
μm powdery；
4) by step 3) in protein powder be dissolved in temperature be 20~25 DEG C, abundant water in the pure water of 250~300g
Change 3~15h, in obtaining protein aqueous solution, then by step 3) in carbohydrate powder, macroelement powder, micro unit
Plain powder, water soluble vitamin powder are dissolved in protein aqueous solution, carry out gentle agitation and obtain well mixed water to mix
Liquid；
5) by step 1) in micro-capsule embedding treatment after fat powder, step 2) in prepare liposoluble vitamin powder
End, meals elite powder, integration of drinking and medicinal herbs component powders, natural plants compound powder sequentially add the water phase of gained in step 4
Solution, and strong agitation is carried out, emulsifying agent and thickener are added, obtain well mixed concentrated emulsions；
6) 20~25 DEG C are added in the concentrated emulsions described in step 5, the pure water of 100~150g and is stirred, while going
The foam of skim-coat, obtains emulsion, then by emulsion under 300-500Bar homogeneous, homogenisation cycle number of times be 2-4 times, Ran Hou
Sterilized at 110~130 DEG C, be cooled to room temperature, nutrition emulsion is obtained, and nutrition emulsion is filling in sterilized packaging bag.
Aforesaid operations step is both needed to be carried out under the protection of inert gas, such as nitrogen protection, to prevent that powder is quick-fried
Fried danger.
Hypoglycemic experiment 1
The experiment of this hypoglycemic is carried out for blank group with the nutrient powder prepared according to embodiment 1~7.
SPF grades of C57BL/6J female mice 130, is randomly divided into normal group 10, diabetes group 120；Male 35.
Normal group is fed with basal feed, and diabetes group is fed with high lipid food, continues 4 weeks.Determine that mouse is emotionally all using vaginal smear method
Phase.Before emotionally, with C57BL/6J male mices 1：1 mates, secondary daily inspection raettin introitus and bedding and padding, and makees vaginal smear inspection
Survey, it was observed that cloudy bolt and vaginal smear sperm, it is determined as pregnant 0d.It is determined that after becoming pregnant, gestational diabetes mellitus group mouse peritoneal injection
STZ (Streptozotocin) 50mg/kg, continuously injects 3d, continues to feed high lipid food；Normal group is fed with normal diet.After 7d, fasting
Can't help water 12h, tail vein takes blood, measurement fasting blood-glucose, and individuality of the blood glucose value more than 11.1mmol/L is considered as glycosuria gravidarum
Sick mouse, control group gives normal diet.
According to becoming pregnant, order chooses gestational diabetes mellitus mouse 64, is divided into each group successively, every group 8, for control group, with
And nutrient powder prepared by embodiment 1~7, (dosage is 1000mg/ in high lipid food for nutrient powder stirring prepared by embodiment 1~7
Kg/day) raise 2 weeks, fasting 12h, survey fasting blood-glucose；Control group chooses 8 according to order of becoming pregnant, and awards chow diet nursing.
Experimental data uses SPSS19 software processings, experimental data to represent that its result is as shown in table 1 with x ± s.
Table 1 is continuously fed with the C57BL/6J Diabetic Pregnancies mouse blood glucose test results of 2 weeks
As seen from the above table, after 14 days are fed with, compared with control group, the C57BL/6J diabetes of 1~7 group of embodiment are pregnant
Mouse blood sugar of being pregnent has conspicuousness to decline, and (a is represented and significant difference, P is compared with normal group<0.05；Aa is represented and compared with normal group
Significant difference, P<0.01；* represent and significant difference, P are compared with control group<0.05；* is represented and significant difference, P is compared with control group
<0.01) nutrient powder that, i.e., prepared by embodiment 1~7 has reduce in various degree blood sugar to act on.
Hypoglycemic experiment 2
The experiment of this hypoglycemic is carried out for the nutrient powder that contrast groups 1, contrast groups 2 are prepared with embodiment 1.
A kind of EA for gestational diabetes mellitus women that contrast groups 1 are prepared using Chinese patent CN103584083A
Preparation, its raw material includes marine animal albumen or Soybean Peptide, laminarin, soft-shelled turtle meat enzymolysis powder, olive oil or tea-seed oil and work
Property probiotics, amino acid, calcium preparation and fruit vegetable powder.
Pregnant woman's diabetes full nutrition formula food that contrast groups 2 are prepared using Chinese patent CN105394763A, its raw material
Extract and new resource food, prebiotics, carbohydrate, amino acid, grease, vitamin and mineral including medicine-food two-purpose
Matter.
From SPF grades of C57BL/6J female mice, determine that gestational diabetes mellitus is small using the experimental procedure in hypoglycemic experiment 1
Mouse, according to becoming pregnant, order chooses gestational diabetes mellitus mouse 30, is divided into each group successively, every group 10, contrast groups 1, contrast groups 2,
Nutrient powder prepared by embodiment 1 stirs in high lipid food (dosage is 1000mg/kg/day) and raises 2 weeks, fasting 12h, surveys empty
Abdomen blood sugar.Measurement data uses average value, and its result is as described in Table 2.
Table 2 is continuously fed with the C57BL/6J Diabetic Pregnancies mouse blood glucose test results of 2 weeks
After 14 days are fed with, the blood glucose rise rate that nutrient powder prepared by embodiment 1 is understood according to table 2 is only 1.1%, its
About the 1/3 of contrast groups 1, about the 1/2 of contrast groups 2, it can thus be concluded that the blood sugar decreasing effect of nutrient powder prepared by embodiment 1 is obvious
Better than contrast groups 1 and contrast groups 2.
From above-described embodiment, various components are mutual in gestational diabetes mellitus tailored version clinical nutrition formula of the present invention
It is engaged, there is provided suitable energy and various critical nutrients needed for diabetic, there is provided completely must micronutrient
Composition, while by integration of drinking and medicinal herbs composition of the addition with effect of lowering blood sugar, natural plants compound and new resource food, each group
Distribution ratio rationally, and is easy to digest and assimilate, and shows that gestational diabetes mellitus tailored version of the present invention faces by above-mentioned experimental data
Bed nutrient formulation feeding C57BL/6J Diabetic Pregnancy mouse blood sugars have conspicuousness to decline, and it can aid in reducing gestational diabetes mellitus
Blood glucose value, reduce the risk of gestational diabetes mellitus, it is ensured that needed for the growth of fetus and normal development.
Specific embodiment of the invention has been described in detail above, but it is only used as example, and the present invention is not intended to limit
In particular embodiments described above.To those skilled in the art, any equivalent modifications carried out to the practicality and replace
In generation, is also all among scope of the invention.Therefore, the equalization made without departing from the spirit and scope of the invention is converted and repaiied
Change, all should be contained within the scope of the invention.
Claims (10)
1. a kind of gestational diabetes mellitus tailored version clinical nutrition is formulated, it is characterised in that the component including following parts by weight：20-
35 parts of protein, 8-15 parts of fat, 25-40 parts of carbohydrate, 3-8 parts of dietary fiber, 0.6-1.2 parts of macroelement, 0.01-
0.03 portion of trace element, 0.005-0.015 portions of liposoluble vitamin, 0.08-0.2 portions of water soluble vitamin, 0.05-0.6 portions of meals
Food elite, 0.5-4 parts of integration of drinking and medicinal herbs composition, 0.1-1 parts of natural plants compound and 0.1-0.4 parts of new resource food；
Wherein, the integration of drinking and medicinal herbs composition be selected from Chinese yam, Semen sesami nigrum, the root of kudzu vine, sealwort, mulberry leaf, matrimony vine, balloonflower root, lily in extremely
Few one kind；
Wherein, the new resource food be selected from first milk basic protein, GABA, chitosan oligosaccharide, eucommia Bark male flower, bamboo-leaves flavones,
At least one in CPP, avenabeta glucosan, yeast beta-dextran, leaf of Moringa, xylo-oligosaccharide.
2. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 1 is formulated, it is characterised in that described natural
Plant compound be selected from l-cn, Glucosamine, FOS, lutein, phytosterol, lycopene, resveratrol,
At least one in allicin.
3. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 1 is formulated, it is characterised in that the new money
Source food is leaf of Moringa and avenabeta glucosan.
4. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 3 is formulated, it is characterised in that the Moringa
The weight ratio of leaf and avenabeta glucosan is 1:1.
5. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 1 is formulated, it is characterised in that the medicine food
Parts by weight with each component in derived components are as follows：Chinese yam 0-1 parts, Semen sesami nigrum 0-1 parts, root of kudzu vine 0-1 parts, sealwort 0-1 parts, mulberry leaf
0-1 parts, matrimony vine 0-1 parts, balloonflower root 0-1 parts, lily 0-1 parts.
6. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 1 is formulated, it is characterised in that the albumen
The good protein weight provided in matter and amino acid accounts for more than the 70% of gross protein weight.
7. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 1 is formulated, it is characterised in that the fat
The ratio of middle n-6 aliphatic acid and n-3 aliphatic acid is 3~4:1.
8. a kind of gestational diabetes mellitus tailored version clinical nutrition according to claim 1 is formulated, it is characterised in that the fat
In monounsaturated fatty acids ratio be higher than saturated fatty acid.
9. the preparation method that a kind of gestational diabetes mellitus tailored version clinical nutrition as claimed in claim 1 is formulated, it is characterised in that
It is powdered that the fat uses micro-capsule embedding techniques to be made, and the integration of drinking and medicinal herbs composition is made powdered by crushing, sieving.
10. preparation method according to claim 9, it is characterised in that the mesh number of the integration of drinking and medicinal herbs composition sieving is 60-
80 mesh.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611209080.7A CN106666728A (en) | 2016-12-23 | 2016-12-23 | Special clinical nutrient composition for gestational diabetes and preparation method of nutrient composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611209080.7A CN106666728A (en) | 2016-12-23 | 2016-12-23 | Special clinical nutrient composition for gestational diabetes and preparation method of nutrient composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106666728A true CN106666728A (en) | 2017-05-17 |
Family
ID=58870375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611209080.7A Pending CN106666728A (en) | 2016-12-23 | 2016-12-23 | Special clinical nutrient composition for gestational diabetes and preparation method of nutrient composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106666728A (en) |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107242550A (en) * | 2017-06-29 | 2017-10-13 | 上海复旦奥医医学科技有限公司 | A kind of male sterility tailored version clinical nutrition formula and preparation method thereof |
| CN107319524A (en) * | 2017-06-29 | 2017-11-07 | 上海复旦奥医医学科技有限公司 | A kind of nephrosis tailored version clinical nutrition formula and preparation method thereof |
| CN107373672A (en) * | 2017-08-23 | 2017-11-24 | 上海奥医生物医药科技有限公司 | A kind of irregular menstruation women tailored version clinical nutrition formula and preparation method thereof |
| CN107373642A (en) * | 2017-07-27 | 2017-11-24 | 广州赛莱拉干细胞科技股份有限公司 | One kind is for diabetes B patient's diet and foodstuffs and preparation method thereof |
| CN107440102A (en) * | 2017-08-23 | 2017-12-08 | 上海奥医生物医药科技有限公司 | A kind of climacteric women tailored version clinical nutrition formula and preparation method thereof |
| CN107440121A (en) * | 2017-08-23 | 2017-12-08 | 上海奥医生物医药科技有限公司 | A kind of Single Obesity tailored version clinical nutrition formula and preparation method thereof |
| CN107440103A (en) * | 2017-08-23 | 2017-12-08 | 上海奥医生物医药科技有限公司 | A kind of respiratory disease tailored version clinical nutrition formula and preparation method thereof |
| CN107616490A (en) * | 2017-08-23 | 2018-01-23 | 上海奥医生物医药科技有限公司 | A kind of postoperative tailored version clinical nutrition formula of children and preparation method thereof |
| CN107927754A (en) * | 2017-12-13 | 2018-04-20 | 上海奥医生物医药科技有限公司 | Tailored version clinical nutrition formula and preparation method thereof is energized during one kind production |
| CN108013454A (en) * | 2017-12-13 | 2018-05-11 | 上海奥医生物医药科技有限公司 | Gynaecological imflammation tailored version clinical nutrition formula and preparation method thereof |
| CN108618129A (en) * | 2018-05-10 | 2018-10-09 | 上海奥医生物医药科技有限公司 | Sarcopenia tailored version clinical nutrition formula and preparation method thereof |
| WO2019024248A1 (en) * | 2017-08-02 | 2019-02-07 | 深圳市领治医学科技有限公司 | Nutritional product for diabetic nephropathy patients |
| WO2019047141A1 (en) * | 2017-09-08 | 2019-03-14 | 北京慧宝源生物技术股份有限公司 | Pharmaceutical composition for controlling blood sugar |
| CN110101088A (en) * | 2019-05-09 | 2019-08-09 | 武汉正轩宇生物科技有限公司 | Accurate nutritional meal replacement composition and its application method for gestational diabetes mellitus prevention and treatment |
| CN110477281A (en) * | 2018-05-14 | 2019-11-22 | 许昌神飞航天生物科技有限公司 | A kind of suitable spacefarer promotes the nutritional preparation of constitution |
| CN110800996A (en) * | 2019-11-07 | 2020-02-18 | 上海奥医高科技实业有限公司 | Special clinical nutrition formula for vomiting of pregnancy and preparation method thereof |
| CN110810837A (en) * | 2018-08-13 | 2020-02-21 | 光谷迈德（武汉）慢性病研究院有限公司 | Special medical food for preventing and improving type 2 diabetes and preparation method and application thereof |
| CN113317496A (en) * | 2021-06-04 | 2021-08-31 | 西安力邦临床营养股份有限公司 | Emulsion with special medical application for relieving diabetes symptoms and preparation method thereof |
| CN114680340A (en) * | 2022-04-26 | 2022-07-01 | 王路 | Formula of polysaccharide multi-dimensional dietary fiber composite powder |
| CN116439368A (en) * | 2023-06-16 | 2023-07-18 | 四川大学华西第二医院 | Nutritional composition for pregnant women and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104286849A (en) * | 2014-09-26 | 2015-01-21 | 上海励成营养产品科技股份有限公司 | Diabetes-specific enteral nutrition multi-polymerization agent |
| CN105029410A (en) * | 2015-06-29 | 2015-11-11 | 南阳市汇博生物技术有限公司 | Diabetes full nutrition emulsion formula food and preparation method thereof |
| CN105942498A (en) * | 2016-05-05 | 2016-09-21 | 上海诗琳美生物科技有限公司 | Functional nutritional food compounds with diabetes-treating effects and preparation methods thereof |
| CN106174585A (en) * | 2016-06-30 | 2016-12-07 | 山东凤凰生物有限公司 | Hypoglycemic compositions and hypoglycemic compound probiotic spy's dietary seafood |
| CN106173826A (en) * | 2016-07-01 | 2016-12-07 | 江丽 | A kind of nutritive powder treating gestational diabetes |
-
2016
- 2016-12-23 CN CN201611209080.7A patent/CN106666728A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104286849A (en) * | 2014-09-26 | 2015-01-21 | 上海励成营养产品科技股份有限公司 | Diabetes-specific enteral nutrition multi-polymerization agent |
| CN105029410A (en) * | 2015-06-29 | 2015-11-11 | 南阳市汇博生物技术有限公司 | Diabetes full nutrition emulsion formula food and preparation method thereof |
| CN105942498A (en) * | 2016-05-05 | 2016-09-21 | 上海诗琳美生物科技有限公司 | Functional nutritional food compounds with diabetes-treating effects and preparation methods thereof |
| CN106174585A (en) * | 2016-06-30 | 2016-12-07 | 山东凤凰生物有限公司 | Hypoglycemic compositions and hypoglycemic compound probiotic spy's dietary seafood |
| CN106173826A (en) * | 2016-07-01 | 2016-12-07 | 江丽 | A kind of nutritive powder treating gestational diabetes |
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107242550A (en) * | 2017-06-29 | 2017-10-13 | 上海复旦奥医医学科技有限公司 | A kind of male sterility tailored version clinical nutrition formula and preparation method thereof |
| CN107319524A (en) * | 2017-06-29 | 2017-11-07 | 上海复旦奥医医学科技有限公司 | A kind of nephrosis tailored version clinical nutrition formula and preparation method thereof |
| CN107373642A (en) * | 2017-07-27 | 2017-11-24 | 广州赛莱拉干细胞科技股份有限公司 | One kind is for diabetes B patient's diet and foodstuffs and preparation method thereof |
| WO2019024248A1 (en) * | 2017-08-02 | 2019-02-07 | 深圳市领治医学科技有限公司 | Nutritional product for diabetic nephropathy patients |
| CN107440103A (en) * | 2017-08-23 | 2017-12-08 | 上海奥医生物医药科技有限公司 | A kind of respiratory disease tailored version clinical nutrition formula and preparation method thereof |
| CN107440121A (en) * | 2017-08-23 | 2017-12-08 | 上海奥医生物医药科技有限公司 | A kind of Single Obesity tailored version clinical nutrition formula and preparation method thereof |
| CN107616490A (en) * | 2017-08-23 | 2018-01-23 | 上海奥医生物医药科技有限公司 | A kind of postoperative tailored version clinical nutrition formula of children and preparation method thereof |
| CN107440102A (en) * | 2017-08-23 | 2017-12-08 | 上海奥医生物医药科技有限公司 | A kind of climacteric women tailored version clinical nutrition formula and preparation method thereof |
| CN107373672A (en) * | 2017-08-23 | 2017-11-24 | 上海奥医生物医药科技有限公司 | A kind of irregular menstruation women tailored version clinical nutrition formula and preparation method thereof |
| CN110300594A (en) * | 2017-09-08 | 2019-10-01 | 北京慧宝源生物技术股份有限公司 | Control the pharmaceutical composition of blood glucose |
| WO2019047141A1 (en) * | 2017-09-08 | 2019-03-14 | 北京慧宝源生物技术股份有限公司 | Pharmaceutical composition for controlling blood sugar |
| US11957726B2 (en) | 2017-09-08 | 2024-04-16 | Beijing Hebabiz Biotechnology Co., Inc. | Pharmaceutical composition for controlling blood sugar |
| CN107927754A (en) * | 2017-12-13 | 2018-04-20 | 上海奥医生物医药科技有限公司 | Tailored version clinical nutrition formula and preparation method thereof is energized during one kind production |
| CN108013454A (en) * | 2017-12-13 | 2018-05-11 | 上海奥医生物医药科技有限公司 | Gynaecological imflammation tailored version clinical nutrition formula and preparation method thereof |
| CN108618129A (en) * | 2018-05-10 | 2018-10-09 | 上海奥医生物医药科技有限公司 | Sarcopenia tailored version clinical nutrition formula and preparation method thereof |
| CN110477281A (en) * | 2018-05-14 | 2019-11-22 | 许昌神飞航天生物科技有限公司 | A kind of suitable spacefarer promotes the nutritional preparation of constitution |
| CN110810837A (en) * | 2018-08-13 | 2020-02-21 | 光谷迈德（武汉）慢性病研究院有限公司 | Special medical food for preventing and improving type 2 diabetes and preparation method and application thereof |
| CN110101088A (en) * | 2019-05-09 | 2019-08-09 | 武汉正轩宇生物科技有限公司 | Accurate nutritional meal replacement composition and its application method for gestational diabetes mellitus prevention and treatment |
| CN110800996A (en) * | 2019-11-07 | 2020-02-18 | 上海奥医高科技实业有限公司 | Special clinical nutrition formula for vomiting of pregnancy and preparation method thereof |
| CN113317496A (en) * | 2021-06-04 | 2021-08-31 | 西安力邦临床营养股份有限公司 | Emulsion with special medical application for relieving diabetes symptoms and preparation method thereof |
| CN114680340A (en) * | 2022-04-26 | 2022-07-01 | 王路 | Formula of polysaccharide multi-dimensional dietary fiber composite powder |
| CN116439368A (en) * | 2023-06-16 | 2023-07-18 | 四川大学华西第二医院 | Nutritional composition for pregnant women and preparation method thereof |
| CN116439368B (en) * | 2023-06-16 | 2023-09-15 | 四川大学华西第二医院 | Nutritional composition for pregnant women and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106666728A (en) | Special clinical nutrient composition for gestational diabetes and preparation method of nutrient composition | |
| CN106490605A (en) | A kind of hypertension of pregnancy tailored version clinical nutrition formula and preparation method thereof | |
| CN106579393A (en) | Special clinical nutrient formula for diabetes and preparation method thereof | |
| CN106983136A (en) | A kind of puerperium conditioning tailored version clinical nutrition formula and preparation method thereof | |
| CN106858620A (en) | A kind of anaemia tailored version clinical nutrition formula and preparation method thereof | |
| CN107319525A (en) | One kind fat-reducing fat reducing tailored version clinical nutrition formula and preparation method thereof | |
| CN106962912A (en) | A kind of hepatopathy tailored version clinical nutrition formula and preparation method thereof | |
| CN108651988A (en) | Nephrosis dialysis tailored version clinical nutrition formula and preparation method thereof | |
| CN108013453A (en) | Children's lactose intolerance tailored version clinical nutrition formula and preparation method thereof | |
| CN107927754A (en) | Tailored version clinical nutrition formula and preparation method thereof is energized during one kind production | |
| CN106616615A (en) | Clinical nutrient formula special for tumor and preparation method of clinical nutrient formula | |
| CN104286849A (en) | Diabetes-specific enteral nutrition multi-polymerization agent | |
| CN105613789A (en) | High-fat and high-dietary-fiber composite animal and plant powdered oil and preparation method and application thereof | |
| CN107616490A (en) | A kind of postoperative tailored version clinical nutrition formula of children and preparation method thereof | |
| CN107319524A (en) | A kind of nephrosis tailored version clinical nutrition formula and preparation method thereof | |
| CN108634324A (en) | A kind of special diet food and preparation method thereof promoting cesarean lactation and nutritional supplementation | |
| CN108077911A (en) | A kind of epileptic's tailored version clinical nutrition formula and preparation method thereof | |
| CN1843130A (en) | Brain tonic flour and food production method | |
| CN108013452A (en) | A kind of puerperal abdominal flatulence gas tailored version clinical nutrition formula and preparation method thereof | |
| CN110074397A (en) | A kind of upgrowth and development of children tailored version clinical nutrition formula and preparation method thereof | |
| CN107440121A (en) | A kind of Single Obesity tailored version clinical nutrition formula and preparation method thereof | |
| CN106174479A (en) | A kind of geriatric nutrition powder and preparation method thereof | |
| CN108703365A (en) | Protein allergy tailored version clinical nutrition formula and preparation method thereof | |
| CN106804730A (en) | The formula milk that the suitable standby pregnant phase treated constipation, period of pregnancy women eat can be prevented | |
| CN101422239A (en) | Combined partner capable of increasing edible rice, flour nutrition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170517 |
|
| RJ01 | Rejection of invention patent application after publication |