CN108013454A - Gynaecological imflammation tailored version clinical nutrition formula and preparation method thereof - Google Patents
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- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention provides a kind of gynaecological imflammation tailored version clinical nutrition formula, including following component and its parts by weight:14 30 parts of protein, 1 10 parts of fat, 45 65 parts of carbohydrate, 5 10 parts of dietary fibers, 0.5 1.5 parts of macroelements, 0.008 0.05 parts of trace elements, 0.008 0.02 parts of liposoluble vitamins, 0.09 0.28 parts of water soluble vitamins, 0.05 2 parts of meals elite, 0.5 3 parts of integration of drinking and medicinal herbs components and 0.005 2 parts of new resource foods;The present invention also provides a kind of preparation method of above-mentioned nutrient formulation.The present invention can improve patient's body function, strengthen nutrition, improve immunity of organisms so as to avoid the recurrent exerbation of gynaecological imflammation, while can alleviate the symptom of gynaecological imflammation.
Description
Technical field
The present invention relates to special medicine purposes formula food field, more particularly to a kind of gynaecological imflammation tailored version clinical nutrition
Formula and preparation method thereof.
Background technology
Recently as immunologic hypofunction, flora imbalance patient numbers be continuously increased and it is clinically unreasonable using anti-
Raw element causes antibody-resistant bacterium to increase, and causes the genital system diseases as caused by microorganism infection to increase year by year.Investigation display, full generation
The different degrees of infection of the adult female of boundary treaty 87% gynaecological imflammation, clinical common gynaecological imflammation have vaginitis, cervicitis,
Endometritis etc., trichomonad, mould, bacterium infection be then cause women with, the major reason of pruritus vulvue.Clinically gynaecology
Inflammation is mainly shown as the symptoms such as pudendal pruritus, scorching hot swelling and pain, leucorrhea increasing, frequent micturition, urgent urination, odynuria, recurrent exerbation, it is prolonged not
More, quality of life and love life are influenced.
For the treatment of gynaecological imflammation, doctor trained in Western medicine medication currently on the market mainly has metronidazole class and miaow chaff azole, using first
Phase positive effect, but after long-time use, due to the drug resistance increase of microorganism, fungistatic effect declines, and patient has to again
Choose;And after metronidazole class drug administration it is more with digestive tract reactions such as Nausea and vomiting, loss of appetite, cramps and
The neurological symptoms such as headache, dizziness, cacesthesia, extremity numbness, incoordination, polyneuritis, are not suitable for pregnant woman
And women breast-feeding their children;Rice bran azole drug after taking it is more with digestive tract reactions such as nausea,vomiting,diarrhea and anorexias and
The cutaneous anaphylaxises such as fash, pruitus, it is also possible to normocytic anemia, leucocyte and decrease of platelet occurs, it is high
Pionemia symptom, is not suitable for Pregnant and lactant women.It can be seen from the above that Western medicine side effect is more, the same of gynaecological imflammation is treated
When can cause other diseases.
Meanwhile for the treatment of gynaecological imflammation, Most patients after topical therapy, symptom can improve quickly or
Disappear, but this does not illustrate that inflammation has been fully recovered, but pathogen is temporarily inhibited.Therefore, gynaecological imflammation is thoroughly cured
Method is on the one hand to adhere to treating, and periodic review, on the other hand will also improve the body function of patient, strengthen nutrition, carry
High immunity of organisms.
It is rare to be used to treat the nutrition class product of gynaecological imflammation currently on the market, only pays attention to drug therapy mostly.Relatively
In doctor trained in Western medicine medication, middle medical drugs then more selects lotion or Chinese herbal medicine formula;For example, in the market treatment endometritis, pelvic infecton
Deng the golden pheasant ball of disease, there is clearing heat and detoxicating, invigorating the spleen dehumidifying, dredging collateral and promoting blood circulation, and have no toxic side effect.
The nutritional support of gynaecological imflammation should cause more attention, for gynaecological imflammation, on the basis of medication treatment,
Also need to improve patient's body function, strengthen nutrition, immunity of organisms is improved, so as to avoid the recurrent exerbation of gynaecological imflammation.City
Many health foods are sold on face, for supplementing the nutrients, but this kind of health products may be than common in terms of fixed healthcare function
Nutriment obtains more, but with not being particularly directed to gynaecological imflammation women, may result in some nutritional ingredients excess, instead
And it is unfavorable for health.For this reason, the rationally sufficiently required nutrition of gynaecological imflammation women, and can be effective can either be provided by developing
The nutrient formulation that gynaecological imflammation is alleviated on ground has great importance.
The content of the invention
The defects of it is an object of the invention to overcome in the prior art, there is provided a kind of gynaecological imflammation tailored version clinical nutrition is matched somebody with somebody
Side and preparation method thereof, it is according to the clinical nutrition feature of gynaecological imflammation, rightly to protein, carbohydrate and fat mass
Ratio is adjusted, replenishing vitamins and dietary fiber, improves patient's body function, strengthens nutrition, improves immunity of organism
Power can alleviate gynaecological imflammation so as to avoid the recurrent exerbation of gynaecological imflammation.
To achieve the above object, the present invention adopts the following technical scheme that:
First purpose of the present invention is to provide a kind of gynaecological imflammation tailored version clinical nutrition formula, including following component and
Its parts by weight:14-30 parts of protein, 1-10 parts of fat, 45-65 parts of carbohydrate, 5-10 parts of dietary fibers, 0.5-1.5
Part macroelement, 0.008-0.05 parts of trace elements, 0.008-0.02 parts of liposoluble vitamins, 0.09-0.28 parts of water soluble vitamins
Raw element, 0.05-2 parts of meals elite, 0.5-3 parts of integration of drinking and medicinal herbs components and 0.005-2 parts of new resource foods.
In order to further optimize above-mentioned clinical nutrition formula, the technical measures that the present invention is taken further include:
Preferably, the protein be hydrolyzing lactoalbumin powder, it is soybean protein isolate, livetin, whole milk powder, complete
At least one of powdered egg, lactoferrin, colostrum, taurine, amino acid, protein peptides.
Wherein, the amino acid is L-lysine-Pidolidone, Pidolidone, L-arginine, L-Trp, L- paddy ammonia
At least one of acid amides, taurine, Valine, l-Isoleucine, L-Leu;The protein peptides for soybean oligopeptide,
At least one of wheat protein peptide, collagen peptide, pupa albumen peptide, laughable peptide, amino peptide.
It is highly preferred that the protein includes hydrolyzing lactoalbumin powder, soybean protein isolate, taurine.
Preferably, it is described fat for saturated fatty acid, polyunsaturated fatty acid, monounsaturated fatty acids, OPO structured lipids,
At least one of DHA, EPA, ARA, phosphatide.
Preferably, the carbohydrate is at least one of rock sugar, maltodextrin, tapioca, resistant dextrin.
Preferably, the dietary fiber be konjaku flour, galactooligosaccharide, oligofructose, oligoisomaltose, soybean it is more
At least one of sugar, cyclodextrin, resistant dextrin, soybean fiber.
Preferably, the macroelement for calcium citrate, L-calcium lactate, calcium monohydrogen phosphate, K-IAO, sodium citrate and
At least one of magnesium gluconate.
Preferably, the trace element is ferrous gluconate, potassium iodide, zinc gluconate, sodium selenite, gluconic acid
At least one of copper, chromium sulfate, manganese gluconate and sodium molybdate.
Preferably, the liposoluble vitamin is vitamin A, beta carotene, vitamin D3, vitamin E, vitamin K1In
At least one.
Preferably, the water soluble vitamin is vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C,
At least one of pantothenic acid, folic acid, nicotinic acid, choline, inositol, biotin.
Preferably, the meals elite is by cereal, potato, greengrocery, Homonemeae, nut-seed class, fish and shrimp, poultry
At least one of meat, fruits.
Wherein, the cereal is selected from rice meal, millet powder, black rice flour, coixlacrymajobi powder, corn flour, wheat germ powder, oat
At least one of powder, buckwheat;The potato is mainly made of common yam rhizome powder;The greengrocery selects pumpkin powder, spinach powder, lotus root
At least one of powder, cucumber powder, broccoli powder, balsam pear powder;The Homonemeae is in mushroom powder, Kelp Powder and white fungus powder
It is at least one;The nut-seed class is mainly made of pumpkin seed powder, the fish and shrimp in soft-shelled turtle powder, white fish meal at least
It is a kind of;The poultry meat is selected from least one of powdered beef, pork liver powder and pig kidney powder;The fruits be selected from red date powder,
At least one of longan powder, cherry powder, papaya powder, emblica powder, apple powder, strawberry powder, banaina.
Preferably, the integration of drinking and medicinal herbs component is arillus longan, honeysuckle, Exocarpium Citri Rubrum, gingko, mulberries, radix glycyrrhizae, Poria cocos, Pu Gong
At least one of English, peach kernel, ginger;More preferably radix glycyrrhizae, Poria cocos, dandelion, peach kernel, ginger.
Preferably, the new resource food is first milk basic protein, γ-aminobutyric acid, chitosan oligosaccharide, bamboo-leaves flavones, junket egg
White phosphoeptide, avenabeta glucosan, Oligomeric manna sugar, stachyose, yeast beta-dextran, newborn mineral salt, xylo-oligosaccharide, Cordyceps militaris
At least one of;More preferably yeast beta-dextran, Cordyceps militaris.
Above-mentioned nutrient formulation can also add suitable natural plants compound;The natural plants compound is left-handed meat
At least one of alkali, Glucosamine, oligofructose, lutein, phytosterol, lycopene, resveratrol, allicin;
More preferably l-cn.
Above-mentioned nutrient formulation can also add suitable Huoxue Herbs.
Preferably, the Huoxue Herbs include Angelica sinensis, gadfly, leech, pangolin, rheum officinale, motherwort.Above-mentioned traditional Chinese medicine ingredients
After compatibility, there is promoting blood circulation and removing blood stasis, reducing phlegm and resolving masses, clearing heat and detoxicating, dispersing the depressed liver-qi and alleviating pain, available for the son caused by stagnation of blood stasis disease
The gynaecological imflammations such as palace myomata, ovarian cyst, endometriosis, chronic pelvic inflammatory disease, while also there is anti-aging antioxygen to be turned into
With having effects that pretty good beneficial face beauty, anti-aging.
Second object of the present invention is to provide a kind of preparation method of above-mentioned gynaecological imflammation tailored version clinical nutrition formula,
It includes the following steps:
Step 1, fat powder, liposoluble vitamin powder and water soluble vitamin powder are prepared using micro-capsule embedding techniques
End;
Step 2, carried, be spray-dried and sifting step prepares integration of drinking and medicinal herbs component powders using crushing, alcohol extracting, water;
Step 3, by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, trace element, meals essence
China, natural plants compound and new resource food are prepared into the powder that particle diameter is 200~350 μm respectively;
Step 4, powder prepared by step 1~3 is sterilized after mixing spare;
Step 5, the mixed powder of step 4 is prepared into by nutrient powder, nutrition emulsion, capsule according to conventional technical means
At least one of agent, tablet, pill or oral liquid;
Wherein, the order of step 1~3 can be replaced mutually.
Finally, a kind of product by above-mentioned gynaecological imflammation tailored version clinical nutrition formula of present invention offer, including nutrient powder,
Nutrition emulsion, capsule, tablet, pill, oral liquid etc..
In above-mentioned preparation method, wherein, the raw material of the integration of drinking and medicinal herbs component is crushed, alcohol extracting concentration, water concentrate
Contracting, and concentrate is subjected to spray drying integration of drinking and medicinal herbs component powders are made;Wherein, the fat and liposoluble vitamin, water
Soluble vitamin is prepared into fat powder and vitamin powder by microcapsules technology respectively.
Preferably, the specific implementation step of the fatty micro-capsule embedding techniques is as follows:A) wall material aqueous solution is prepared:Take wheat
Bud dextrin, whole-fat milk powder, dietary fiber, inulin, PURE WHEY, oligoisomaltose, 1 gram of soybean fiber, Arabic gum, ice
Icing Sugar is stirred evenly with water;B) monoglyceride is dissolved in grease;C) Tween 80 is dissolved in wall material aqueous solution;D) mixing step
Rapid b) the liquid with step c), obtains mixed solution;E) stabilizer agar is added in mixed solution, constant volume, 20000r/min
Lower high speed dispersion;F) under conditions of homogenization pressure is 25MPa, homogeneous 2 times, is made homogeneous emulsion;G) by obtained homogeneous
Emulsion is spray-dried, and inlet air temperature is 195 DEG C, and leaving air temp is 80 DEG C;Collect and fat powder is made.
Preferably, the specific implementation step of the micro-capsule embedding techniques of the liposoluble vitamin is as follows:By predetermined weight part
Several liposoluble vitamins selects carragheen, Arabic gum to carry out 2 emulsifying homogeneous under high pressure as wall material as core
Processing, the emulsifying homogeneous time is 10~15min, then carries out instantaneous drying of spraying, and fat-soluble dimension is prepared with 60~80 mesh sieves point
Raw element powder.
Preferably, the specific implementation step of the microcapsules technology of the water soluble vitamin is as follows:By predetermined weight number
Water soluble vitamin as core, select maltodextrin, lipoprotein to be used as wall material, be uniformly mixed, the instantaneous drying of spraying, with 60
~80 mesh sieves point prepare water soluble vitamin powder.
Preferably, the preparation process of the integration of drinking and medicinal herbs component powders is as follows:Using pulverizer to predetermined weight number
Raw material is crushed, and the raw material of crushing is placed in container, is added 3~8 times of the water that weight is raw material weight, is carried out immersion 3
~4 it is small when, then carry out 30~60min of decoction to soak, filtering removes raw material, leaves and takes decoction liquor, decoction liquor is sprayed
Mist is dried, and integration of drinking and medicinal herbs component powders are prepared with 60~80 mesh sieves point.
Preferably, in the step 5, suitable food thickening agent and food additives are optionally increased.
Wherein, the food thickening agent be guar gum, it is xanthans, locust bean gum, konjac glucomannan, pectin, carragheen, agar, bright
At least one of glue, Arabic gum;The food additives are at least one in Aspartame, food flavor spices, brown sugar
Kind.
It is highly preferred that the food thickening agent is carragheen, Arabic gum, guar gum;The food additives are A Si
Ba Tian, food flavor spices.
Being used in the present invention includes radix glycyrrhizae, Poria cocos, dandelion, peach kernel, the integration of drinking and medicinal herbs component of ginger, integration of drinking and medicinal herbs component
The effect that traditional dietotherapy is unable to reach can either be obtained, and obviates conventional medicament and takes caused side effect, mentioned component
There is promoting blood circulation and removing blood stasis, disinfecting detoxifying, anti-inflammatory analgetic, enhancing immunity of organisms after compatibility synergy.
Glycyrrhiza perennial herb, root is sturdy with root-like stock, is a kind of help Chinese herbal medicine, available for the heart qi deficiency, taste gas
Empty, lassitude hypodynamia;It can be additionally used in the strong of reconciliation some drugs, have the function that to reduce stimulation of the other drugs to intestines and stomach;
Radix glycyrrhizae also has the solution that anti-inflammatory, anti-allergic effects, extract of licorice root and glycyrrhizic acid have some poisonous substances similar glucuronic acid at the same time
Toxic action;Gynaecological imflammation can be treated, patients in remission simultaneously neutralizes other drugs pharmacological property.
Poria cocos slightly sweet flavor is put down, and enters the heart, lung, the spleen channel, available for tonifying lung spleen, controls the deficiency of vital energy, antitoxic heart-soothing and sedative;Gather rich in Poria cocos
Sugar, has inhibitory action to various bacteria, the bacterium infection available for treatment gynaecological imflammation;Containing pachymic acid, there is enhancing to be immunized
The effect of power, antitumor and calm, hypoglycemic etc., helps to improve the resistivity of gynaecological imflammation patient, can avoid gynaecology
The recurrent exerbation of inflammation.
Dandelion is rich in vitamin A, vitamin C and potassium, and contains iron, calcium, vitamin B2, vitamin B1, magnesium, vitamin
B6, folic acid, copper etc., at the same it is also a variety of containing taraxol, taraxacin, choline, organic acid, synanthrin etc. in dandelion plant
Health-nutrition component, is the preferable nutritional supplementation source of gynaecological imflammation patient, helps to improve body resistance against diseases;Dandelion also has
There are clearing heat and removing internal heat, diuresis anti-inflammatory, available for the bacterium infection for the treatment of gynaecological imflammation, beneficial to recovery.
Peach kernel has effect promoting blood circulation and removing blood stasis, its water decoction-alcohol sedimentation liquid can make in vitro rabbit ear vein vascular flow increase, there is diastole
Blood vessel function, its extract can accelerate blood flow in anesthetized rat Microcirculation of Liver using administration in arteria linenalis, scorching for gynaecology
The mucosal tissue adhesion of disease patient, connective tissue are glued, muscle layer adhesion etc. all has good therapeutic effect;Peach kernel have anti-inflammatory it
Effect, its water extract can suppress the generation of the skin-sensitizing antibodies and house mouse spleen hemolytic cell in mice serum, the extraction of its ethanol
Thing, which takes orally, can suppress the color that mouse contains PCA reactions (passive cutaneous anaphylaxis) caused by the antiserum of skin hypersensitivity antibody
Plain seepage discharge, the treatment available for gynaecological imflammation.
Ginger has disinfecting detoxifying, the effect of swelling and pain relieving, its extracting solution, which has, to be significantly inhibited dermatophyte and kill connections the moon
The effect of road trichomonad, available for bacterium is killed, treat inflammation;Ginger have cold extermination warm the womb effect, its main component for gingerol,
Ginger ketenes, zingiberone etc., have sweating cold dispelling effect, are clinically used for treatment anemofrigid cold at initial stage, exogenous cough etc., can be with invigorating the spleen temperature
Stomach, inspires YANG QI tending to rise in nature, promotes blood circulation, dispels stomach syncope due to pathogenic cold and accumulates, therefore the symptom such as cramp for alleviating gynaecological imflammation
With curative effect well.
The present invention uses above-mentioned technical proposal, compared with prior art, has the following technical effect that:
Gynaecological imflammation tailored version clinical nutrition formula of the present invention includes hydrolyzing lactoalbumin powder, soybean separation protein
In vain, 8 kinds of essential amino acids needed for gynaecological imflammation patient are supplemented, balancedly albumen the multiple proteins general equilibrium such as taurine
Matter, fat, carbohydrate proportioning contribute to supplement gynaecological imflammation patient due to a variety of dietetic contraindications and caused by protein and
The shortage of energy;
Strengthen iron, zinc, zinc is one of the essential trace elements of the human body, and supplement zinc can promote gynaecological imflammation patient's appetite,
Prevention is malnutritive, and enhancing muscle power, zinc has immune system obvious humidification, participates in defence work(of the cell to free radical
Can, improve resistivity of the gynaecological imflammation patient to germ;Supplement iron can improve the immunity of body, increase neutrocyte
With the phagocytic function of phagocyte, while the anti-infection ability of body can also strengthened, improve gynaecological imflammation patient to germ
Resistivity;
Purple Perilla Seed Oil microcapsule powder, wherein Purple Perilla Seed Oil are the highest food plants of known alpha-linolenic acid (a-LNA) content
Oil, and it is best with Purple Perilla Seed Oil quality, and alpha-linolenic acid content is up to 70% or so in oil;It can make nutritional supplement, help to carry
The body immunity of high gynaecological imflammation patient;There is antithrombotic, suppress inflammation, available for treatment gynaecological imflammation disease
Shape;Also there is antiallergy and adaptability is improved in adverse circumstance and suppresses some cancer cells.Microencapsulation then improves biography
The shortcomings that product function factor of uniting is unstable, poorly water-soluble, low bioavilability, is more conducive to absorption of human body, improves nutrition profit
With value.
A variety of fat-soluble type vitamin rational proportions, vitamin E have antioxidation, can remove toxicity in humans's
Free radical, vitamin E or a kind of critically important vasodilator and anticoagulant;Vitamin A can promote cell propagation and
Growth, protects the complete and healthy of each organ epithelial structures, and promote the synthesis of immunoglobulin;
Add Cordyceps militaris, cordycepin therein, can antiviral, antibacterial, substantially suppress tumour growth;Adenosine therein, can
With antiviral, antibacterial, suppress Platelet congregation prevention thrombosis, can also eliminate face spot, it is anti-ageing wrinkle resistant;Wherein Cordyceps sinensis polysaccharide,
Immunity is improved, slows down aging, strengthens the body resistance to consolidate the constitution, cardioprotection, liver, the effect of anti-convulsion;Rich in selenium, immunoglobulin is stimulated
With the generation of antibody, strengthen immunity of organism and oxidation resistance.Cordyceps militaris can be not only used for treatment gynaecological imflammation symptom, it may also be used for
Enhancing resistivity prevents from recurring, while also has anti-oxidant anti-aging effect, is the staple product for gynaecological imflammation patient.
Yeast beta-dextran is added, yeast beta-dextran is with the infection such as raising body resistance virus, bacterium, adjusting body
Gastral Tiny ecosystem, promotes the excretion of nuisance in the propagation and enteron aisle of internal beneficial bacterium, stimulates Skin Cell activity, enhancing
The immunity protection function of skin itself, efficient repairing sheath skin, reduces wrinkle of skin and produces, the function of delay skin aging.
Reasonably combined integration of drinking and medicinal herbs component, can play the role of promoting blood circulation and removing blood stasis, toxin-expelling and face nourishing, enhancing immunity of organisms,
Be conducive to the remission of gynaecological imflammation patient and avoid the recurrent exerbation of symptom.
The present invention is by selecting rational basal nutrient element, using the proportioning of general equilibrium, while adds to have and adjusts woman
Section's inflammatory patients immunity, promoting blood circulation and removing blood stasis, disinfecting detoxifying, the integration of drinking and medicinal herbs component of anti-inflammatory analgetic, natural plants compound, new money
The specific nutrients such as source food, and adjust its proportioning and carry out compatibility synergy with basal nutrient element, gynaecological imflammation patient is supplemented comprehensively
Required necessary nutritional ingredient, and the nutrient formulation is easier to be absorbed by gynaecological imflammation people digest, gives full play to its each component
The effect of, so as to avoid the recurrent exerbation of gynaecological imflammation, while gynaecological imflammation can be alleviated.
Embodiment
The present invention provides a kind of gynaecological imflammation tailored version clinical nutrition formula, including following component and its parts by weight:
14-30 parts of protein, 1-10 parts of fat, 45-65 parts of carbohydrate, 5-10 parts of dietary fibers, 0.5-1.5 parts of macroelements,
0.008-0.05 parts of trace elements, 0.008-0.02 parts of liposoluble vitamins, 0.09-0.28 parts of water soluble vitamins, 0.05-2
Part meals elite, 0.5-3 parts of integration of drinking and medicinal herbs components and 0.005-2 parts of new resource foods.
With reference to embodiment, the embodiment of the present invention is further described.Following embodiments are only used for more
Add and clearly demonstrate technical scheme, and be not intended to limit the protection scope of the present invention and limit the scope of the invention.
Embodiment 1
Gynaecological imflammation tailored version clinical nutrition formula of the present invention includes maltodextrin 46.5g, hydrolyzing lactoalbumin
Powder 20g, Purple Perilla Seed Oil microcapsule powder 6g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Kelp Powder 0.4g, mushroom powder
0.4g, broccoli powder 0.4g, balsam pear powder 0.6g, radix glycyrrhizae 0.4g, Poria cocos 0.6g, dandelion 0.6g, peach kernel 0.6g, ginger 0.6g,
Cordyceps militaris 0.4g, yeast beta-dextran 0.4g, magnesium 0.166g, phosphorus 0.185g, calcium 0.42g, iron 0.018g, zinc 0.016g, dimension life
Plain A 0.0012g, vitamin D30.0000015g, vitamin E 0.016g, vitamin B10.002g, vitamin B2
0.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, nicotinic acid 0.02g, folic acid 0.0004g,
Pantothenic acid 0.006g, taurine 0.12g.
Embodiment 2
Gynaecological imflammation tailored version clinical nutrition formula of the present invention includes maltodextrin 51.5g, hydrolyzing lactoalbumin
Powder 20g, Purple Perilla Seed Oil microcapsule powder 1g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Kelp Powder 0.4g, mushroom powder
0.4g, broccoli powder 0.4g, balsam pear powder 0.6g, radix glycyrrhizae 0.4g, Poria cocos 0.6g, dandelion 0.6g, peach kernel 0.6g, ginger 0.6g,
Cordyceps militaris 0.4g, yeast beta-dextran 0.4g, magnesium 0.166g, phosphorus 0.185g, calcium 0.42g, iron 0.018g, zinc 0.016g, dimension life
Plain A 0.0012g, vitamin D30.0000015g, vitamin E 0.016g, vitamin B10.002g, vitamin B2
0.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, nicotinic acid 0.02g, folic acid 0.0004g,
Pantothenic acid 0.006g, taurine 0.12g.
Embodiment 3
Gynaecological imflammation tailored version clinical nutrition formula of the present invention includes maltodextrin 47.1g, hydrolyzing lactoalbumin
Powder 20g, Purple Perilla Seed Oil microcapsule powder 6g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Kelp Powder 0.4g, mushroom powder
0.4g, broccoli powder 0.4g, balsam pear powder 0.6g, radix glycyrrhizae 0.4g, Poria cocos 0.6g, dandelion 0.6g, peach kernel 0.6g, ginger 0.6g,
Cordyceps militaris 0.1g, yeast beta-dextran 0.1g, magnesium 0.166g, phosphorus 0.185g, calcium 0.42g, iron 0.018g, zinc 0.016g, dimension life
Plain A 0.0012g, vitamin D30.0000015g, vitamin E 0.016g, vitamin B10.002g, vitamin B2
0.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, nicotinic acid 0.02g, folic acid 0.0004g,
Pantothenic acid 0.006g, taurine 0.12g.
Embodiment 4
Gynaecological imflammation tailored version clinical nutrition formula of the present invention includes maltodextrin 49.3g, hydrolyzing lactoalbumin
Powder 20g, Purple Perilla Seed Oil microcapsule powder 6g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Kelp Powder 0.4g, mushroom powder
0.4g, broccoli powder 0.4g, balsam pear powder 0.1g, radix glycyrrhizae 0.1g, Poria cocos 0.1g, dandelion 0.1g, peach kernel 0.1g, ginger 0.1g,
Cordyceps militaris 0.4g, yeast beta-dextran 0.4g, magnesium 0.166g, phosphorus 0.185g, calcium 0.42g, iron 0.018g, zinc 0.016g, dimension life
Plain A 0.0012g, vitamin D30.0000015g, vitamin E 0.016g, vitamin B10.002g, vitamin B2
0.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, nicotinic acid 0.02g, folic acid 0.0004g,
Pantothenic acid 0.006g, taurine 0.12g.
Embodiment 5
A kind of preparation method of gynaecological imflammation tailored version clinical nutrition formula as described in 1~embodiment of embodiment 4 is as follows:
1) powdered oil (powder fat) is prepared:
A) wall material aqueous solution is prepared:Take 8 grams of maltodextrin, 11 grams of whole-fat milk powder, dietary fiber 2 grams of (resistant dextrin), chrysanthemums
0.5 gram of powder, 5 grams of PURE WHEY, 0.5 gram of oligoisomaltose, 1 gram of soybean fiber, 0.2 gram of Arabic gum, 0.5 gram of lactose,
2 grams of candy sugar powder, 50 milliliters of water stir evenly and (have ready conditions and heat while stirring to 60 DEG C, keep 30 minutes postcoolings to room temperature).
B) 0.1 gram (total solid concentration is 0.2%) is taken uniformly to be dissolved in (perilla herb oil in 0.21 milliliter of grease monoglyceride
0.18 milliliter, 0.03 milliliter of medium chain triglyceride).
C) 0.1 gram (total solid concentration is 0.2%) is taken uniformly to be dissolved in wall material aqueous solution Tween 80.
D) the wall material aqueous solution of the mixed plant grease and addition Over emulsfication agent Tween 80 of Over emulsfication agent monoglyceride will be added
It is sufficiently mixed.
E) addition stabilizer agar takes 0.1 gram (total solid concentration be 0.2%) to be settled into after mixed solution with water
200 milliliters (total solid concentration be 25%), high speed dispersion 2 minutes under 20000r/min.
F) homogenization pressure is 25MPa, and homogeneous 3 times (every time 5 minutes), is made homogeneous emulsion.
G) obtained emulsion is spray-dried, inlet air temperature is 195 DEG C, and leaving air temp is 80 DEG C.Collect powder
Grease (powder fat).
2) integration of drinking and medicinal herbs component powders are prepared:The raw material of predetermined weight number is crushed using pulverizer, will be crushed
Raw material be placed in container, the raw material of predetermined weight number is crushed using pulverizer, the raw material of crushing is placed in container
In, 3~5 times of 60~80% ethanol that weight is raw material weight are added, is soaked, extracted 2 times, merges alcohol extract and concentrates
To no alcohol taste;After the active compound dregs of a decoction fling to ethanol, add weight and soaked for 6~8 times of water of raw material weight, to soak into
Row decocts 30~60min, and filtering removes raw material, leaves and takes decoction liquor;Merge alcohol extract and decoction liquor after concentration, and it is carried out
Spray drying, finally prepares integration of drinking and medicinal herbs component powders with 60~80 mesh sieves point;
3) vitamin powder is prepared:Using the liposoluble vitamin of predetermined weight number as core, oligomeric different malt is selected
Sugar is used as wall material, carries out 2 emulsifying homogeneous processing under high pressure, the emulsifying homogeneous time is 10~15min, then carries out spraying wink
When dry, point prepare liposoluble vitamin powder with 60~80 mesh sieves;Using the water soluble vitamin of predetermined weight number as core
Material, selects maltodextrin, oligoisomaltose to be uniformly mixed as wall material, spray instantaneous dry, prepared with 60~80 mesh sieves point
Water soluble vitamin powder;
4) by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, trace element, meals elite with
And new resource food is prepared into the powder that particle diameter is 150~250 μm respectively;(step 1) -4) order can mutually replace)
5) by step 1) -4) prepare powder sterilized after mixing in the similar devices such as mixer it is spare;
6) the prepared food powder in step 5) is prepared into by the prepared food powder obtained by step 5) according to conventional technical means
At least one of nutrient powder, nutrition emulsion, capsule, tablet, pill or oral liquid.
In step 6), optionally increase suitable food thickening agent, food additives and related formulation auxiliary material.
The food thickening agent is guar gum, in xanthans, locust bean gum, konjac glucomannan, pectin, carragheen, agar, gelatin, Arabic gum
At least one, the food additives are Aspartame, food flavor spices, at least one of brown sugar;More preferably OK a karaoke club
Glue, Arabic gum, guar gum, Aspartame, food flavor spices.
Aforesaid operations step is both needed to carry out under the protection of inert gas, such as nitrogen, argon gas, helium etc., to prevent from producing
The danger of green powder explosion.
According to described with the classifications such as powdery, graininess, capsule shape, tablet shape, beverage can be prepared into.
Embodiment 6
1) influence of nutrient formulation preparation prepared by the present invention to normal mouse weight;
Take nutrient powder prepared by the embodiment of the present invention 1~4 to be tested, while set comparative example 1, comparative example 2, comparative example 3
And blank control group, comparative example 1 is using the battalion for not adding Cordyceps militaris in the nutrient formulation of embodiment 2 and prepared by yeast beta-dextran
Powder is supported, comparative example 2 is used using the nutrient powder for not adding the preparation of integration of drinking and medicinal herbs component in the nutrient formulation of embodiment 2, comparative example 3
Nutrient powder prepared by Huoxue Herbs Angelica sinensis, gadfly, leech, pangolin, rheum officinale, motherwort is added in the nutrient formulation of embodiment 2,
Blank control group feeds physiological saline.
PF grades of BALB/C mices, are female, weight 20~25g, every group 10.According to the daily gavage of 0.3g/10g dosage
Mouse, continuous 30 days.Fed to single cage during intragastric administration on mice, measure it daily and take in appetite, claim within every 3 days 1 weight, final meter
Each group weight gain is calculated, is shown in Table 1.
Influence of the 1 gynaecological imflammation tailored version clinical nutrition formula of table to mouse weight
Through toxotest, rat its weight, food-intake, liver function, renal function, blood, routine urinalysis and each histopathology are examined
Look into discovery without exception.
From the above results, which has no mouse weight growth and significantly affects that it can maintain mouse
Normal physiological function, does not produce harmful effect to the normal growth of mouse, that is, shows that nutrient formulation of the present invention has
Maintain material needed for mouse normal growth.
2) therapeutic effect of nutrient formulation preparation prepared by the present invention to gynaecological imflammation;
Take nutrient powder prepared by the embodiment of the present invention 1~4 to be tested, while set comparative example 1, comparative example 2 and control group,
Comparative example 1 is using the nutrient powder for not adding Cordyceps militaris in the nutrient formulation of embodiment 2 and prepared by yeast beta-dextran, comparative example 2
Using the nutrient powder for not adding the preparation of integration of drinking and medicinal herbs component in the nutrient formulation of embodiment 2, control group takes golden pheasant ball.
Selection suffers from gynaecological imflammation (chronic cervicitis, vaginitis) patient 350, is randomly divided into 7 groups, every group of 50 people, try
Test the time 6 months, embodiment 1~4 and comparative example 1~3 take the nutrition powder of above-mentioned preparation, each 15g, 1 day 3 times;Control
Group takes golden pheasant ball, each 2g, 1 day 3 times,
The criterion of therapeutic effect:Recovery from illness:Absence of vagina, itching of vulva pain symptom, vaginal fluid check without exception;It is aobvious
Effect:Vagina, itching of vulva pain symptom improve, and vaginal fluid checks without exception;Effectively:Vaginal fluid checks normally and other diseases
Shape exists, or other symptoms are disappeared, mitigated and vaginal fluid inspection exception;It is invalid:Symptom, sign and inspection, which added, not to be become
Change.(SPSS statistical methods are used, the comparison of enumeration data rate uses X2Examine.) its result of the test such as table 2 below.
Therapeutic effect (n (%)) of the 2 gynaecological imflammation tailored version clinical nutrition formula of table to gynaecological imflammation
From the above results, embodiment 1~4, comparative example 1~3 and control group are effective in cure to treatment gynaecological imflammation, but
Nutrient formulation prepared by the present invention and better than comparative example 1~2 and control the effect of with the addition of comparative example 3 of Huoxue Herbs
Group.
From above-described embodiment, gynaecological imflammation tailored version clinical nutrition formula of the present invention is gynaecological imflammation patient
Sufficient comprehensive nutritional supplementation is provided, gynaecological imflammation trouble is adjusted to improve the constitution of gynaecological imflammation patient, while add to have
Person's immunity, promoting blood circulation and removing blood stasis, disinfecting detoxifying, the integration of drinking and medicinal herbs component of anti-inflammatory analgetic, natural plants compound, new resource food etc.
Specific nutrient, and adjust its proportioning with basal nutrient element carry out compatibility synergy, comprehensively supplement gynaecological imflammation patient needed for must
Must nutritional ingredient, and the nutrient formulation is easier the effect of being absorbed by gynaecological imflammation people digest, giving full play to its each component, from
And the recurrent exerbation of gynaecological imflammation is avoided, while gynaecological imflammation can be alleviated.
The specific embodiment of the present invention is described in detail above, but it is intended only as example, it is of the invention and unlimited
It is formed on particular embodiments described above.To those skilled in the art, it is any to the equivalent modifications that carry out of the present invention and
Substitute also all among scope of the invention.Therefore, the impartial conversion made without departing from the spirit and scope of the invention and
Modification, all should be contained within the scope of the invention.
Claims (8)
1. a kind of gynaecological imflammation tailored version clinical nutrition formula, it is characterised in that including following component and its parts by weight:14-
30 parts of protein, 1-10 parts of fat, 45-65 parts of carbohydrate, 5-10 parts of dietary fibers, 0.5-1.5 parts of macroelements,
0.008-0.05 parts of trace elements, 0.008-0.02 parts of liposoluble vitamins, 0.09-0.28 parts of water soluble vitamins, 0.05-2
Part meals elite, 0.5-3 parts of integration of drinking and medicinal herbs components and 0.005-2 parts of new resource foods;
Wherein, the protein for hydrolyzing lactoalbumin powder, soybean protein isolate, livetin, whole milk powder, dried whole-egg,
At least one of lactoferrin, colostrum, taurine, amino acid, protein peptides;
Wherein, the new resource food is first milk basic protein, γ-aminobutyric acid, chitosan oligosaccharide, bamboo-leaves flavones, casein phosphoric acid
In peptide, avenabeta glucosan, Oligomeric manna sugar, stachyose, yeast beta-dextran, newborn mineral salt, xylo-oligosaccharide, Cordyceps militaris extremely
Few one kind.
A kind of 2. gynaecological imflammation tailored version clinical nutrition formula according to claim 1, it is characterised in that the protein
Including hydrolyzing lactoalbumin powder, soybean protein isolate, taurine.
3. a kind of gynaecological imflammation tailored version clinical nutrition formula according to claim 1, it is characterised in that the fat is
At least one in saturated fatty acid, polyunsaturated fatty acid, monounsaturated fatty acids, OPO structured lipids, DHA, EPA, ARA, phosphatide
Kind.
4. a kind of gynaecological imflammation tailored version clinical nutrition formula according to claim 1, it is characterised in that the meals are fine
Tie up as konjaku flour, galactooligosaccharide, oligofructose, oligoisomaltose, soybean polyoses, cyclodextrin, resistant dextrin, soybean fiber
At least one of.
5. a kind of gynaecological imflammation tailored version clinical nutrition formula according to claim 1, it is characterised in that the medicine food is same
Derived components are at least one of arillus longan, honeysuckle, Exocarpium Citri Rubrum, gingko, mulberries, radix glycyrrhizae, Poria cocos, dandelion, peach kernel, ginger.
6. a kind of gynaecological imflammation tailored version clinical nutrition formula according to claim 5, it is characterised in that the medicine food is same
Derived components include radix glycyrrhizae, Poria cocos, dandelion, peach kernel, ginger.
A kind of 7. gynaecological imflammation tailored version clinical nutrition formula according to claim 1, it is characterised in that new resource food
Including yeast beta-dextran and Cordyceps militaris.
8. according to a kind of preparation method of gynaecological imflammation tailored version clinical nutrition formula according to any one of claims 1 to 7,
It is characterized in that, it includes the following steps:
Step 1, fat powder, liposoluble vitamin powder and water soluble vitamin powder are prepared using micro-capsule embedding techniques;
Step 2, carried, be spray-dried and sifting step prepares integration of drinking and medicinal herbs component powders using crushing, alcohol extracting, water;
Step 3, by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, trace element, meals elite,
Natural plants compound and new resource food are prepared into the powder that particle diameter is 200~350 μm respectively;
Step 4, powder prepared by step 1~3 is sterilized after mixing spare;
Step 5, the mixed powder of step 4 is prepared into by nutrient powder, nutrition emulsion, capsule, piece according to conventional technical means
At least one of agent, pill or oral liquid;
Wherein, the order of step 1~3 can be replaced mutually.
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