CN106804730A - The formula milk that the suitable standby pregnant phase treated constipation, period of pregnancy women eat can be prevented - Google Patents
The formula milk that the suitable standby pregnant phase treated constipation, period of pregnancy women eat can be prevented Download PDFInfo
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Abstract
The invention provides a kind of suitable standby pregnant phase prevented and treating constipation, the formula milk that period of pregnancy women eats, by skimmed milk power, desalted whey powder, plant fat powder, whole milk powder, concentrated whey protein powder, FOS, phosphatide, DHA algal oil-bound distemper, choline bitartrate, lactoferrin powder, potassium chloride, calcium carbonate, magnesia, zinc gluconate, ferric pyrophosphate, sodium selenite and multivitamin hybrid modulation, can general equilibrium meet the standby pregnant phase, period of pregnancy female population and the ambilateral nutritional need of development of fetus, can avoid passing through again increases food intake dose come the excess weight growth that is plain and causing that supplements the nutrients.The milk powder product of present method invention is in good taste, it is only necessary to which warm water is brewed, and Instant Drinks are convenient, is standby pregnant phase, nutritional ingredient needed for pregnancy period supplement pregnant woman fetus, promotes the best nutritional product of normal fetal development and pregnant woman health.
Description
Technical field
The present invention relates to formula milk, more particularly to can prevent that what the suitable standby pregnant phase treated constipation, period of pregnancy women ate matches somebody with somebody
Square milk powder.
Background technology
Pregnancy period includes pregnant early stage, second trimester, pregnant latter stage.Standby pregnant phase and pregnant early stage are the important periods of embryo nidation development,
Second trimester fetal growth starts to accelerate, and pregnant latter stage fetal tissue organ is increased rapidly, the required battalion that grows of pregnancy period fetus
Support and be required to pregnant women by placental transport supply.
The physiology of pregnant women and metabolism can occur larger change because adapting to the nutritional need of gestational period fetus.First
Pregnancy period endocrine can change, and parent ovary and placental hormone can increase, and thyroxine and other levels can also change, and parent will be mended
Fill the nutrient such as energy and calcium nutrition material.Secondly pregnancy period digestive function can change, and indigestion easily occur, should supplement in time
Calcium, iron, vitamin B12With folic acid meeting pregnant woman, fetus to the situation of the increase in demand of nutrient.Pregnancy period volumetric blood and into
Branch changes, and may result in pregnant woman's physiologic anemia.The glucose of pregnancy period pregnant woman blood plasma, amino acid, iron and water soluble vitamin
Raw element, such as vitamin C, folic acid, vitamin B6, vitamin B12, biological cellulose content reduces.Renal function can also change, glucose,
Amino acid and water-soluble (vitamin) B2, folic acid, nicotinic acid, pyridoxal metabolite discharge rate increase.The body weight in pregnancy period can be suitable
Increase, fetus and parent both sides body weight can increase, and fetus will grow, parent energy ezpenditure increases, maternal genital official
Grow and for postpartum milk secretion does fat depot.
Pregnancy period energy requirement increases, but nutrient needs to increase and increases more than energy.Amino acid needed for fetus early development
Parent is needed largely to take in Macronutrient protein to provide.Lipid is diet energy source, wherein more than phosphatide and long-chain not
Saturated fatty acid such as arachidonic acid (ARA) and DHA (DHA) are that Fetal Brain and retinal development institute are required,
These are both needed to parent offer.The pregnancy period demand of parent micronutrient minerals and vitamins can also increase.Particularly mineral
Matter calcium, iron, iodine, zinc are essential to embryo growth and development, and reduction or shortage can cause development of fetus bad or even deformity, right
Parent will also result in influence, such as hypoferric anemia.Metabolism and development of the vitamin content to fetus are also most important in maternal,
Vitamin A, vitamin D, vitamin E, vitamin K, B family vitamin (vitamin B1, vitamin B2, vitamin B6), folic acid etc. it is right
The intelligence development of fetus, growth metabolism play the role of irreplaceable.
Increasing research shows that maternal nutrition is unbalance and unfavorable in utero nutrient environment can directly affect the next generation
Gene expression and metabolism status.Many countries all encourage standby pregnant phase and pregnancy period to answer many Supplement of folic acid, pregnancy period parent folic acid now
Loss can increase, and demand (being progestational 1.5~2 times) becomes big, and the shortage of parent folic acid may increase filial generation metabolism
The onset risk of syndrome.Micronutrient minerals and vitamins lack to parent and the healthy important role of fetus.
Research display, pregnancy period supplement calcium can reduce the danger of parent hypertension, preeclampsia and pre-eclampsia.Nowadays, pregnant woman anemia is still
It is a common disease, and there are some researches show pregnant early stage asiderosis and baby's premature labor, low birth weight are relevant.The benefit of pregnancy period zinc
Fill also most important, the sufficient zinc of parent can promote growing and prevent fetal congenital lopsided for fetus.There is document report
Parent VAD is relevant with baby's premature labor, hypoevolutism and low birth weight.Vitamin D deficiency can cause parent and filial generation
Metabolic calcium disorder.The appropriate supplement of pregnancy period vitamin E can produce beneficial effect to prevention neonatal hemolytic.Pregnancy period pregnant woman B race's dimension
The shortage of raw element may influence parent gastrointestinal function, cause hypoferric anemia, and development of fetus is slow etc..
The production technology of current formula milk mainly has two kinds of dry and wet.Dry technology for production is simple, but to raw material
Requirement it is very strict, external most enterprise is used, but domestic rare dry process, typically using wet processing, i.e., need to be to thing
Material is concentrated and is spray-dried.And dry process method main advantage is easily controllable addition, it is to avoid because of nutrients
The heat treatment of matter and the nutriment that causes is lost, have the disadvantage the bad control of the uniformity of mixing, and product sanitary index not
It is easy to control.
The content of the invention
It is an object of the invention to provide the formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat
Powder, with relaxing bowel, nurses one's health enteron aisle, improves the effect of constipation, can meet pregnancy period normal fetal and grow and parent metabolism
Nutritional need.
The present invention is adopted the following technical scheme that：
The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, including following weight parts
Raw material：Skimmed milk power 30-35 parts, desalted whey powder 25-30 parts, plant fat powder 10-20 parts, whole milk powder 10-15 parts, concentration
PURE WHEY 3-6 parts, 3-6 parts of FOS (FOS), phosphatidase 0 .3-0.6 parts, 1.0-2.0 parts of DHA algal oil-bound distemper, lactoferrin
Powder 0.1-0.5 parts, choline bitartrate 0.2-0.6 parts, zinc gluconate 0.01-0.05 parts, ferric pyrophosphate 0.05-0.1 parts, carbon
Sour calcium 0.5-1.5 parts, potassium chloride 0.2-0.8 parts, magnesia 0.1-0.4 parts, sodium selenite 0.002-0.008 parts, vitamin E
0.01-0.04 parts, B B-complex 0.1-0.5 parts.
The desalted whey powder is desalted whey powder commonly used in the art, and general ash content is below 1.5%；
The plant fat powder is plant fat powder commonly used in the art, and with good water solubility, breast more dissipates more
Property；
The concentrated whey protein powder is concentrated whey protein powder commonly used in the art, and its protein content is generally
34-82%；
FOS is a kind of bifidus factor for improving function of intestinal canal, can be effectively improved diabetic's intestinal health
Level.After intake FOS, the fluctuation of human body level will not be caused, be the good sweet taste of diabetes patients
Agent.Additionally, FOS may additionally facilitate the cell of Bifidobacterium, cell wall constituent and mucilage secretion propagation, therefore with carrying
Effect of immunity of organisms high.
Total lipid content is 53-69% in the phosphatide, and monounsaturated fatty acids content is 5-12%, polyunsaturated fatty acid
Content is 33-40%, is provided by du pont company.
DHA content >=10% in the DHA algal oil-bound distemper, by it is good must excellent biotechnology (Wuhan) share have
Limit company provides.
Lactoferrin content >=90% in the lactoferrin powder, is provided by Western Dairy Products company of New Zealand.
The composition of the B B-complex is：The μ gRE of retinol1 80, calciferol .5 μ g, the μ g of vitamin K1 1.8, dimension life
Plain B10.26mg, vitamin B20.51mg, vitamin B60.43mg, vitamin B121.32 μ g, vitamin C 35.3mg, nicotinic acid
1.71mg, pantothenic acid 0.99mg, folic acid 195 μ g, taurine 7.9mg.
A kind of formula milk that suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, preparation technology includes following
Step：
(1) by the concentrated whey protein powder of formula ratio 50%, FOS (FOS), phosphatide, DHA algal oil-bound distemper, lactoferrin
It is powder, choline bitartrate, zinc gluconate, ferric pyrophosphate, calcium carbonate, potassium chloride, magnesia, sodium selenite, vitamin E, multiple
Close vitamin to be well mixed, obtain compound A；
(2) concentrated whey protein powder of formula ratio 50% and the plant fat powder of formula ratio 20% are taken as carrier, will be mixed
Close during material A adds carrier and be uniformly mixed, obtain compound B；
(3) skimmed milk power, desalted whey powder, the plant fat powder of formula ratio 80% and whole milk powder are mixed equal
It is even, obtain compound C；
(4) compound B and compound C is mixed, is stirred, you can.
Temperature, humidity, mixing time and preservation time and temperature can influence the stability of milk powder between batch mixing.Therefore milk powder
The link such as production, packaging, storage, transport should all control temperature.Temperature is less than 28 DEG C, batch mixing between the batch mixing of milk powder of the present invention
Between relative humidity be less than 55%, 15~25min of mixing time, storage-stable is preferable.Less than 30 DEG C of storages, fatty vitamin etc.
Nutriment oxidation can preferably keep powder quality more slowly.In general, 20 DEG C of storages of milk powder are after 24 months, can be preferable
Keep powder quality.Formula milk color and luster of the invention is milky white uniform；Free from admixture, caking and granular size is consistent；Have pure
Frankincense taste.Solubility presses the deliquescent measure of GB/T5413.29-1997 Milk powder and formula foods for infant and young children up to 88%-99%.
The present invention determines raw material sanitary index using GB, after raw produce meets national standard, using small powder and part
The method of aniseed premix is sufficiently mixed raw material.Present invention process is using DHA algal oil-bound distemper, lactoferrin powder, B B-complex
(other powderies such as whole milk powder, skimmed milk power or desalted whey powder add the pulvis raw material directly made with other Deng small powder pulvis
Plus thing) be sufficiently mixed with physical method and be uniformly directly prepared into formula milk.Its main program is first by various small powder (DHA algal oils
Powder pulvis etc.) it is pre-mixed with a small amount of milk powder, then it is sufficiently mixed with major ingredient again.
《Chinese residents dietary guidelines》There are special recommendation, including the sufficient energy of pregnant early stage supplement to pregnant women meals；
Pregnancy period increases fish, meat, egg, milk, the intake of marine product；PA keeps the normal growth of body weight.According to the diet of Chinese residents
Custom, the excessive growth that required nutrient easily causes body weight is supplemented by increasing food intake dose.With it is of the prior art
Pregnant milk powder formula is compared, and folic acid is rich in the formula milk, and contain lactoferrin, lactalbumin, phosphatide, choline, calcium iron
All kinds of nutrients such as zinc and high-quality DHA, can meet the demand that the metabolism of pregnancy period parent and normal fetal grow.The pregnant woman matches somebody with somebody
Square milk powder, suitable standby pregnant phase, period of pregnancy female population are used, with wide market prospects wide.
Part recommended amounts are the maximum of national food safety standard GB31601-2015 requirement maternal nutritional supplements daily
50g.The nutrient index and national standard index reduced value of the nutritional formula milk powder that the standby pregnant phase, period of pregnancy are applicable see the table below 1
With table 2：
Required component target contrast table in the maternal nutritional supplement of table 1
Component target contrast table may be selected in the maternal nutritional supplement of table 2
The sensory evaluation of table 3 milk powder
The present invention can also add 0.1-0.5 parts of compound Chinese medicine extract in formula, and the compound Chinese medicine extract is by powder
What the Chinese medicine of the dietotherapeutics such as Pueraria lobota, SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, Chinese olive, mung bean sprouts was made.The compound Chinese medicine extract
With the other components compatibility in prescription emulsifiable powder, intestines peristalsis be can further strengthen, standby pregnant phase, period of pregnancy women easily appearance improved
Constipation problem.Simple water extraction is carried out after each raw material mixing in compound Chinese medicine extraction composition formula of the present invention, the extract for obtaining
Synergy can be formed in terms of constipation is improved with prescription emulsifiable powder, but be carried using the compound Chinese medicine that extraction process of the invention is obtained
Thing is taken, improves the effect of constipation more preferably, can also extend the shelf-life of the formula milk.
Compound Chinese medicine extract is added in step (1), by it with concentrated whey protein powder, FOS (FOS), phosphatide,
DHA algal oil-bound distemper, lactoferrin powder etc. are mixed.
The compound Chinese medicine extract is made up of the raw material that following weight is matched：Longan seed 10-20 parts, 5-10 parts of thatch pin,
Flax 0.5-1 parts, Pachyrhizua angulatus 1-3 parts, 10-20 parts of thumb indigo plant, turnip 5-10 parts, SEMEN SINAPIS ALBAE 10-20 parts, Fermented Soybean 10-15 parts, it is white
Flower of hyacinth dolichos 1-5 parts, Chinese olive 5-10 parts, mung bean sprouts 20-30 parts, semen allii tuberosi 20-30 parts, coriander 5-10 parts, Honeysuckle flower 1-3 parts, cloth
2-6 parts of slag leaf；
The preparation method of the compound Chinese medicine extract is：
(1) semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 30-40min at 70-80 DEG C, then by itself and Chinese olive, mung bean sprouts
Mixing, adds this six kinds of water of 3-6 times of raw material gross weight that 5-10min is decocted at 100 DEG C, and filtering obtains filtrate a；
(2) to the water and filtrate a that 8-10 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, decocted at 100 DEG C
Boil 10-15min, be then cooled to 85-90 DEG C, add longan seed, thatch pin, flax, Pachyrhizua angulatus, thumb indigo plant, turnip, 85-90 DEG C after
Continuous heating 30-40min, filtering obtains filtrate b；
(3) filtrate b stands concentrate drying after 10-15h, obtains pulverulent solids as compound Chinese medicine extract.
The present invention is commercially available prod using raw material.
Advantages of the present invention：The formula milk uses plant oil formula, there is rational energy-structure, is rich in alpha-whey egg
The formula milk of white and A A/D H A, using the teaching of the invention it is possible to provide the enough nutrition needed for meeting infant physical growth.Lactoferrin+folic acid+dimension
Raw element A+ vitamin B2s can prevent Iron-Deficiency Anemia in Pregnancy.Folic acid, DHA, choline, linoleic acid plus linolenic acid is to infant brain god
Through waiting development important.Be especially added with relaxing bowel, nurse one's health the prebiotics (FOS) of gut flora, and FOS also has drop blood
The effect that fat, norcholesterol and promotion calcium iron magnesium absorb.Standby pregnant phase body of women trophic level can be strengthened, to breed healthy baby
It is ready.The nutritional need that pregnancy period normal fetal grows with parent metabolism can be met.Nutritional formula milk powder of the invention
Mouthfeel is all good, and taste is aromatic, and warm water brews i.e. edible, convenient and swift, is the optimal of element that supplement the nutrients standby pregnant phase and period of pregnancy
Nutriment.
Specific embodiment
Embodiment 1：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, including it is following
The raw material of weight portion：33 parts of skimmed milk power, 28 parts of desalted whey powder, 15 parts of plant fat powder, 13 parts of whole milk powder, condensed whey
5 parts of albumen powder, 4 parts of FOS (FOS), phosphatidase 0 .4 parts, 1.7 parts of DHA algal oil-bound distemper, 0.3 part of lactoferrin powder, hydrogen tartrate
0.5 part of choline, 0.03 part of zinc gluconate, 0.07 part of ferric pyrophosphate, 0.9 part of calcium carbonate, 0.7 part of potassium chloride, magnesia 0.3
Part, 0.006 part of sodium selenite, 0.03 part of vitamin E, 0.4 part of B B-complex.
Preparation technology is comprised the following steps：
(1) by the concentrated whey protein powder of formula ratio 50%, FOS (FOS), phosphatide, DHA algal oil-bound distemper, lactoferrin
It is powder, choline bitartrate, zinc gluconate, ferric pyrophosphate, calcium carbonate, potassium chloride, magnesia, sodium selenite, vitamin E, multiple
Close vitamin to be well mixed, obtain compound A；
(2) concentrated whey protein powder of formula ratio 50% and the plant fat powder of formula ratio 20% are taken as carrier, will be mixed
Close during material A adds carrier and be uniformly mixed, obtain compound B；
(3) skimmed milk power, desalted whey powder, the plant fat powder of formula ratio 80% and whole milk powder are mixed equal
It is even, obtain compound C；
(4) compound B and compound C is mixed, is stirred, you can.
Embodiment 2：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, including it is following
The raw material of weight portion：34 parts of skimmed milk power, 27 parts of desalted whey powder, 18 parts of plant fat powder, 14 parts of whole milk powder, condensed whey
6 parts of albumen powder, 5 parts of FOS (FOS), phosphatidase 0 .6 parts, 1.7 parts of DHA algal oil-bound distemper, 0.4 part of lactoferrin powder, hydrogen tartrate
0.4 part of choline, 0.03 part of zinc gluconate, 0.06 part of ferric pyrophosphate, 0.9 part of calcium carbonate, 0.6 part of potassium chloride, magnesia 0.2
Part, 0.003 part of sodium selenite, 0.03 part of vitamin E, 0.5 part of B B-complex.
Remaining is with embodiment 1.
Embodiment 3：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, including it is following
The raw material of weight portion：31 parts of skimmed milk power, 29 parts of desalted whey powder, 13 parts of plant fat powder, 15 parts of whole milk powder, condensed whey
3 parts of albumen powder, 4 parts of FOS (FOS), phosphatidase 0 .6 parts, 1.5 parts of DHA algal oil-bound distemper, 0.4 part of lactoferrin powder, hydrogen tartrate
0.3 part of choline, 0.02 part of zinc gluconate, 0.05 part of ferric pyrophosphate, 0.7 part of calcium carbonate, 0.8 part of potassium chloride, magnesia 0.3
Part, 0.007 part of sodium selenite, 0.02 part of vitamin E, 0.3 part of B B-complex.
Remaining is with embodiment 1.
Embodiment 4：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, with embodiment 3
Difference be：0.3 part of compound Chinese medicine extract is with the addition of in formula.
The preparation technology of the formula milk is comprised the following steps：
(1) by the concentrated whey protein powder of formula ratio 50%, FOS (FOS), phosphatide, DHA algal oil-bound distemper, lactoferrin
It is powder, choline bitartrate, zinc gluconate, ferric pyrophosphate, calcium carbonate, potassium chloride, magnesia, sodium selenite, vitamin E, multiple
Close vitamin, compound Chinese medicine extract to be well mixed, obtain compound A；
(2) concentrated whey protein powder of formula ratio 50% and the plant fat powder of formula ratio 20% are taken as carrier, will be mixed
Close during material A adds carrier and be uniformly mixed, obtain compound B；
(3) skimmed milk power, desalted whey powder, the plant fat powder of formula ratio 80% and whole milk powder are mixed equal
It is even, obtain compound C；
(4) compound B and compound C is mixed, is stirred, you can.
The compound Chinese medicine extract is made up of the raw material that following weight is matched：15 parts of longan seed, 8 parts of thatch pin, flax
0.6 part, 2 parts of Pachyrhizua angulatus, blue 18 parts of thumb, 9 parts of turnip, 12 parts of SEMEN SINAPIS ALBAE, 13 parts of Fermented Soybean, 2 parts of Flos Semen Lablab Album, 6 parts of Chinese olive, mung bean
25 parts of bud, 25 parts of semen allii tuberosi, 6 parts of coriander, 2 parts of Honeysuckle flower, 5 parts of strophanthus divaricatus；
The preparation method of the compound Chinese medicine extract is：
(1) semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 35min at 75 DEG C, then it is mixed with Chinese olive, mung bean sprouts,
Add the water of this 5 times of six kinds of raw material gross weight that 8min is decocted at 100 DEG C, filtering obtains filtrate a；
(2) to the water and filtrate a that 9 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, in 100 DEG C of decoctions
12min, is then cooled to 85 DEG C, adds longan seed, thatch pin, flax, Pachyrhizua angulatus, thumb indigo plant, turnip, and 85 DEG C are continued to heat 35min,
Filtering, obtains filtrate b；
(3) filtrate b stands concentrate drying after 12h, obtains pulverulent solids as compound Chinese medicine extract.
Embodiment 5：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, with embodiment 4
Difference be：0.1 part of compound Chinese medicine extract is with the addition of in formula.
The compound Chinese medicine extract is made up of the raw material that following weight is matched：10 parts of longan seed, 5 parts of thatch pin, flax
0.5 part, 1 part of Pachyrhizua angulatus, blue 10 parts of thumb, 5 parts of turnip, 10 parts of SEMEN SINAPIS ALBAE, 10 parts of Fermented Soybean, 1 part of Flos Semen Lablab Album, 5 parts of Chinese olive, mung bean
20 parts of bud, 20 parts of semen allii tuberosi, 5 parts of coriander, 1 part of Honeysuckle flower, 2 parts of strophanthus divaricatus；
The preparation method of the compound Chinese medicine extract is：
(1) semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 30min at 70 DEG C, then it is mixed with Chinese olive, mung bean sprouts,
Add the water of this 3 times of six kinds of raw material gross weight that 5min is decocted at 100 DEG C, filtering obtains filtrate a；
(2) to the water and filtrate a that 8 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, in 100 DEG C of decoctions
10min, is then cooled to 90 DEG C, adds longan seed, thatch pin, flax, Pachyrhizua angulatus, thumb indigo plant, turnip, and 90 DEG C are continued to heat 40min,
Filtering, obtains filtrate b；
(3) filtrate b stands concentrate drying after 15h, obtains pulverulent solids as compound Chinese medicine extract.
Embodiment 6：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, with embodiment 4
Difference be：0.5 part of compound Chinese medicine extract is with the addition of in formula.
The compound Chinese medicine extract is made up of the raw material that following weight is matched：20 parts of longan seed, 10 parts of thatch pin, flax
1 part, 3 parts of Pachyrhizua angulatus, blue 20 parts of thumb, 10 parts of turnip, 20 parts of SEMEN SINAPIS ALBAE, 15 parts of Fermented Soybean, 5 parts of Flos Semen Lablab Album, 10 parts of Chinese olive, mung bean
30 parts of bud, 30 parts of semen allii tuberosi, 10 parts of coriander, 3 parts of Honeysuckle flower, 6 parts of strophanthus divaricatus；
The preparation method of the compound Chinese medicine extract is：
(1) semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 40min at 80 DEG C, then it is mixed with Chinese olive, mung bean sprouts,
Add the water of this 6 times of six kinds of raw material gross weight that 10min is decocted at 100 DEG C, filtering obtains filtrate a；
(2) to the water and filtrate a that 10 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, in 100 DEG C of decoctions
15min, is then cooled to 85 DEG C, adds longan seed, thatch pin, flax, Pachyrhizua angulatus, thumb indigo plant, turnip, and 85 DEG C are continued to heat 30min,
Filtering, obtains filtrate b；
(3) filtrate b stands concentrate drying after 10h, obtains pulverulent solids as compound Chinese medicine extract.
Embodiment 7：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, with embodiment 4
Difference be：
The compound Chinese medicine extract is made up of the raw material that following weight is matched：0.6 part of flax, 2 parts of Pachyrhizua angulatus, thumb indigo plant 18
Part, 9 parts of turnip, 12 parts of SEMEN SINAPIS ALBAE, 13 parts of Fermented Soybean, 2 parts of Flos Semen Lablab Album, 6 parts of Chinese olive, 25 parts of mung bean sprouts, 25 parts of semen allii tuberosi, Yuan
6 parts of Sui, 2 parts of Honeysuckle flower, 5 parts of strophanthus divaricatus；
The preparation method of the compound Chinese medicine extract is：
(1) semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 35min at 75 DEG C, then it is mixed with Chinese olive, mung bean sprouts,
Add the water of this 5 times of six kinds of raw material gross weight that 8min is decocted at 100 DEG C, filtering obtains filtrate a；
(2) to the water and filtrate a that 9 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, in 100 DEG C of decoctions
12min, is then cooled to 85 DEG C, adds flax, Pachyrhizua angulatus, thumb indigo plant, turnip, and 85 DEG C are continued to heat 35min, and filtering is filtered
Liquid b；
(3) filtrate b stands concentrate drying after 12h, obtains pulverulent solids as compound Chinese medicine extract.
Embodiment 8：The formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, with embodiment 4
Difference be：
The preparation method of the compound Chinese medicine extract is：In formula after various raw material mixing, 10 times of its gross weight is added
Water decoct 12min at 100 DEG C, be then cooled to 90 DEG C, continue to heat 30-40min, filtering, concentration is dry after filtrate stands 12h
It is dry, obtain pulverulent solids as compound Chinese medicine extract.
1. zoopery：Cleaning grade female sd inbred rats (10 week old) 30, male and female mouse mates mating.Selection is become pregnant raettin 20
Only, 2 groups are randomly divided into, control group and experimental group,
Every group 10., to gestation, experimental group is according to formula milk (embodiment 3) and normal rats feed for daily normal diet
Each 50% proportioning feeds rat, and control group gives normal rats feed.Until pregnant mouse produces newborn mouse, newborn mouse body weight is weighed.
During feeding, all animal skin hairs are normal, have no and become thin, and without animal dead, each group animal stool and urine is just
Often, abnormal behavior is had no.Weight growth pattern as shown in table 4, all animals entirety growth and development processes are normal, weight from
Experiment is increased more than 1.4 times at the end of starting to experiment.Dams become pregnant before experimental group and control animals weight it is not bright
Significant difference not, the body weight weight of antenatal experimental group rat apparently higher than blank control group (P ＜ 0.01), sub- mouse body weight constitution of being born
Amount is significantly higher than control group (P ＜ 0.01).
This shows that experimental group dams nutrition condition makes moderate progress, and the body weight weight of tire mouse can strengthen.We can see that
Folic acid, OPO structural fatties, high-quality DHA, high-quality protein lactalbumin and lactoferrin, prebiotics are added in formula milk
FOS, phosphatide/choline, calcium iron zinc, multivitamin and the types of functionality nutrient is waited can further to improve dams nutrition shape
Condition, strengthens the vital sign of tire mouse.
The experimental group of table 4 and control group dams are pregnant, antenatal and its sub- mouse Birth Weight situation contrast (x ± s, n=10)
Note：* is with control group difference extremely significantly (P ＜ 0.01).
2. influence of the inventive formulation milk powder to mouse bowel movement
1. animal packet:Cleaning grade kunming mice 100 is taken, male and female half and half, body weight 20-25g is randomly divided into 10 groups, i.e.,
Normal group, model control group and 8 test groups, every group 10.2. model is prepared:In addition to Normal group, remaining each group
Mouse subcutaneous injection morphine hydrochloride 2.5mg/ (kg days), totally 5 days, and mouse tail is wiped with 75% cotton ball soaked in alcohol in the 1st day
Distend the blood vessels hyperemia, cuts off rat-tail tip 0.3cm, then immerses in 37 DEG C or so warm water rat-tail wound, until mouse is lost
Blood about 0.5ml is removed, astriction of deficiency of blood type model is made.3. medication:Simultaneously, Normal group and model control group are small for modeling
Mouse gavage distilled water, gavage gives prescription emulsifiable powder 6g/kg body weight obtained in embodiment 1-8 respectively for 8 test group mouse.Each group is every
It is administered once, continuous 5 days.During last dose, 2% india ink indicator is added in distilled water and liquid.4. index observing:
After last dose, each group mouse is respectively placed in the beaker for be covered with filter paper to be observed, and records the flat of the 1st black excrement of discharge
The equal time, while recording total grain number and average stool weight of average defecation in last dose 4 hours.
Influence of the inventive formulation milk powder of table 5 to astriction of deficiency of blood type model mice bowel movement
As shown in Table 5, the defecation situation of mouse is generally better than embodiment 1-3 in embodiment 4-6, in being combined in embodiment 8
The extraction process of medicament extract is provided without technical scheme, and its effect is more slightly worse than embodiment 4-6.It is combined in embodiment 7
The formula of Chinese medical extract is provided without technical scheme, even if the extraction process of compound Chinese medicine extract employs this
The technical scheme of invention, but still the effect for cooperateing with and improving constipation, its effect can not be formed with the other components in formula milk
It is more or less the same with embodiment 1-3.
3. acceleration for stabilization experiment：Claim formula milk obtained in 20g embodiments 1-8 to load aluminium foil pouch respectively, extrude air,
Sealing, continuous storage 8 months, monthly sample 1 time under the conditions of being placed in 45 DEG C, and whether observation milk powder goes bad.
Do not go bad：Formula milk grows smell well, and taste is aromatic, with pure strong frankincense taste, uniform granularity, breast
Yellow powder.
It is slight rotten：Formula milk has a small amount of small caking, and color is without significant change, and smell is good, reconstitute trial test mouthfeel compared with
It is good.
It is rotten：There is small caking in formula milk, color is slightly deep, after reconstituting, mouthfeel is general.
The acceleration for stabilization experimental result of table 6
Equivalent to 4d is preserved at room temperature at 25 DEG C, formula milk obtained in embodiment 1-3 preserves 7 to 45 DEG C of storage 1d at 45 DEG C
Start to go bad after individual month, formula milk obtained in embodiment 4-6 starts to go bad after being preserved 9 months at 45 DEG C, illustrates embodiment 4-6
The obtained formula milk shelf-life is more long than formula milk obtained in embodiment 1-3 8 months.
Claims (5)
1. the formula milk that a kind of suitable standby pregnant phase for preventing treating constipation, period of pregnancy women eat, it is characterised in that：Including under
State the raw material of weight portion：Skimmed milk power 30-35 parts, desalted whey powder 25-30 parts, plant fat powder 10-20 parts, whole milk powder
10-15 parts, concentrated whey protein powder 3-6 parts, FOS 3-6 parts, phosphatidase 0 .3-0.6 parts, 1.0-2.0 parts of DHA algal oil-bound distemper, breast
0.1-0.5 parts of ferritin powder, choline bitartrate 0.2-0.6 parts, zinc gluconate 0.01-0.05 parts, ferric pyrophosphate 0.05-
0.1 part, calcium carbonate 0.5-1.5 parts, potassium chloride 0.2-0.8 parts, magnesia 0.1-0.4 parts, sodium selenite 0.002-0.008
Part, vitamin E 0.01-0.04 parts, B B-complex 0.1-0.5 parts.
2. the formula milk that a kind of suitable standby pregnant phase for preventing treating constipation as claimed in claim 1, period of pregnancy women eat, its
It is characterised by：Preparation technology is comprised the following steps：
（1）By the concentrated whey protein powder of formula ratio 50%, FOS（FOS）, phosphatide, DHA algal oil-bound distemper, lactoferrin powder, wine
Stone acid hydrogen choline, zinc gluconate, ferric pyrophosphate, calcium carbonate, potassium chloride, magnesia, sodium selenite, vitamin E, compound dimension life
Element is well mixed, obtains compound A；
（2）The concentrated whey protein powder of formula ratio 50% and the plant fat powder of formula ratio 20% are taken as carrier, compound A is added
To enter be uniformly mixed in carrier, obtain compound B；
（3）By skimmed milk power, desalted whey powder, the plant fat powder of formula ratio 80% and whole milk powder mixing and stirring, obtain mixed
Close material C；
（4）Compound B and compound C is mixed, is stirred, you can.
3. the formula milk that a kind of suitable standby pregnant phase for preventing treating constipation as claimed in claim 1, period of pregnancy women eat, its
It is characterised by：0.1-0.5 parts of compound Chinese medicine extract can be also added in formula.
4. the formula milk that a kind of suitable standby pregnant phase for preventing treating constipation as claimed in claim 3, period of pregnancy women eat, its
It is characterised by：The compound Chinese medicine extract is made up of the raw material that following weight is matched：Longan seed 10-20 parts, 5-10 parts of thatch pin,
Flax 0.5-1 parts, Pachyrhizua angulatus 1-3 parts, 10-20 parts of thumb indigo plant, turnip 5-10 parts, SEMEN SINAPIS ALBAE 10-20 parts, Fermented Soybean 10-15 parts, it is white
Flower of hyacinth dolichos 1-5 parts, Chinese olive 5-10 parts, mung bean sprouts 20-30 parts, semen allii tuberosi 20-30 parts, coriander 5-10 parts, Honeysuckle flower 1-3 parts, cloth
2-6 parts of slag leaf；
The preparation method of the compound Chinese medicine extract is：
（1）Semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 30-40min at 70-80 DEG C, then it is mixed with Chinese olive, mung bean sprouts
Close, add this six kinds of water of 3-6 times of raw material gross weight that 5-10min is decocted at 100 DEG C, filtering obtains filtrate a；
（2）To water and filtrate a that 8-10 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, 10- is decocted at 100 DEG C
15min, is then cooled to 85-90 DEG C, adds longan seed, thatch pin, flax, Pachyrhizua angulatus, thumb indigo plant, turnip, and 85-90 DEG C is continued to heat
30-40min, filtering, obtains filtrate b；
（3）Filtrate b stands concentrate drying after 10-15h, obtains pulverulent solids as compound Chinese medicine extract.
5. the formula milk that a kind of suitable standby pregnant phase for preventing treating constipation as claimed in claim 4, period of pregnancy women eat, its
It is characterised by：The compound Chinese medicine extract is made up of the raw material that following weight is matched：15 parts of longan seed, 8 parts of thatch pin, flax
0.6 part, 2 parts of Pachyrhizua angulatus, blue 18 parts of thumb, 9 parts of turnip, 12 parts of SEMEN SINAPIS ALBAE, 13 parts of Fermented Soybean, 2 parts of Flos Semen Lablab Album, 6 parts of Chinese olive, mung bean
25 parts of bud, 25 parts of semen allii tuberosi, 6 parts of coriander, 2 parts of Honeysuckle flower, 5 parts of strophanthus divaricatus；
The preparation method of the compound Chinese medicine extract is：
（1）Semen allii tuberosi, coriander, Honeysuckle flower, strophanthus divaricatus toast 35min at 75 DEG C, then it is mixed with Chinese olive, mung bean sprouts, add
The water of this 5 times of six kinds of raw material gross weight decocts 8 min at 100 DEG C, and filtering obtains filtrate a；
（2）To water and filtrate a that 9 times of its gross weight is added in SEMEN SINAPIS ALBAE, Fermented Soybean, Flos Semen Lablab Album, 12 are decocted at 100 DEG C
Min, is then cooled to 85 DEG C, adds longan seed, thatch pin, flax, Pachyrhizua angulatus, thumb indigo plant, turnip, and 85 DEG C are continued to heat 35min, mistake
Filter, obtains filtrate b；
（3）Filtrate b stands concentrate drying after 12h, obtains pulverulent solids as compound Chinese medicine extract.
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Cited By (7)
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| CN108432880A (en) * | 2018-03-09 | 2018-08-24 | 东北农业大学 | A kind of formula milk and preparation method thereof suitable for standby pregnant Mrs phase |
| CN109077322A (en) * | 2018-08-30 | 2018-12-25 | 山西康惠中天医药科技有限公司 | A kind of maternal diet complete nourishing powder |
| CN109275778A (en) * | 2018-08-30 | 2019-01-29 | 苏州佩普肽康生物科技有限公司 | A kind of women helps pregnant food formula of special diet and preparation method thereof |
| CN110558551A (en) * | 2019-09-29 | 2019-12-13 | 亨美久健康科技(广东)有限公司 | full-nutrition breakfast for first stage of pregnant women and preparation method thereof |
| CN110771870A (en) * | 2019-09-29 | 2020-02-11 | 亨美久健康科技(广东)有限公司 | Second-stage full-nutrition breakfast for pregnant women and preparation method thereof |
| CN111955554A (en) * | 2020-06-05 | 2020-11-20 | 广州翼酵堂生物科技有限公司 | Camel milk powder for pregnant and lying-in women and production process thereof |
| CN115989836A (en) * | 2022-11-29 | 2023-04-21 | 黑龙江飞鹤乳业有限公司 | Nutritional composition containing lactoferrin and probiotics, food and application |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108432880A (en) * | 2018-03-09 | 2018-08-24 | 东北农业大学 | A kind of formula milk and preparation method thereof suitable for standby pregnant Mrs phase |
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| CN110558551A (en) * | 2019-09-29 | 2019-12-13 | 亨美久健康科技(广东)有限公司 | full-nutrition breakfast for first stage of pregnant women and preparation method thereof |
| CN110771870A (en) * | 2019-09-29 | 2020-02-11 | 亨美久健康科技(广东)有限公司 | Second-stage full-nutrition breakfast for pregnant women and preparation method thereof |
| CN111955554A (en) * | 2020-06-05 | 2020-11-20 | 广州翼酵堂生物科技有限公司 | Camel milk powder for pregnant and lying-in women and production process thereof |
| CN115989836A (en) * | 2022-11-29 | 2023-04-21 | 黑龙江飞鹤乳业有限公司 | Nutritional composition containing lactoferrin and probiotics, food and application |
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Application publication date: 20170609 |