CN106166157B - 作为防乙型肝炎病毒感染的抗病毒剂的氨磺酰苯甲酰胺衍生物 - Google Patents

作为防乙型肝炎病毒感染的抗病毒剂的氨磺酰苯甲酰胺衍生物 Download PDF

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CN106166157B
CN106166157B CN201610312350.0A CN201610312350A CN106166157B CN 106166157 B CN106166157 B CN 106166157B CN 201610312350 A CN201610312350 A CN 201610312350A CN 106166157 B CN106166157 B CN 106166157B
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compounds
fluoro
benzamide
hbv
difluorophenyl
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CN106166157A (zh
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巨涛·郭
晓东·徐
蒂莫西·M·布洛克
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Baru S Bloomberg Institute
Drexel University
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Baru S Bloomberg Institute
Drexel University
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
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    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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CN201610312350.0A 2011-07-01 2012-06-29 作为防乙型肝炎病毒感染的抗病毒剂的氨磺酰苯甲酰胺衍生物 Expired - Fee Related CN106166157B (zh)

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US9399619B2 (en) 2016-07-26
JP6516705B2 (ja) 2019-05-22
WO2013006394A1 (en) 2013-01-10
EP2726459A1 (en) 2014-05-07
CN103889953B (zh) 2016-06-08
US20160101074A1 (en) 2016-04-14
CN106166157A (zh) 2016-11-30
JP2017014225A (ja) 2017-01-19
EP2726459B1 (en) 2019-09-11
CN103889953A (zh) 2014-06-25
JP2014523901A (ja) 2014-09-18
US9758477B2 (en) 2017-09-12
US20190337891A1 (en) 2019-11-07
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US20140206666A1 (en) 2014-07-24

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