CN105669865A - 结合人cd27的抗体及其用途 - Google Patents
结合人cd27的抗体及其用途 Download PDFInfo
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- CN105669865A CN105669865A CN201610122341.5A CN201610122341A CN105669865A CN 105669865 A CN105669865 A CN 105669865A CN 201610122341 A CN201610122341 A CN 201610122341A CN 105669865 A CN105669865 A CN 105669865A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C07—ORGANIC CHEMISTRY
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
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- C07K2317/00—Immunoglobulins specific features
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- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32372010P | 2010-04-13 | 2010-04-13 | |
| US61/323,720 | 2010-04-13 | ||
| US201161471459P | 2011-04-04 | 2011-04-04 | |
| US61/471,459 | 2011-04-04 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180029048.XA Division CN103154034B (zh) | 2010-04-13 | 2011-04-13 | 结合人cd27的抗体及其用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105669865A true CN105669865A (zh) | 2016-06-15 |
Family
ID=44534592
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180029048.XA Active CN103154034B (zh) | 2010-04-13 | 2011-04-13 | 结合人cd27的抗体及其用途 |
| CN201610122341.5A Pending CN105669865A (zh) | 2010-04-13 | 2011-04-13 | 结合人cd27的抗体及其用途 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180029048.XA Active CN103154034B (zh) | 2010-04-13 | 2011-04-13 | 结合人cd27的抗体及其用途 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US9169325B2 (enExample) |
| EP (2) | EP3165540A1 (enExample) |
| JP (2) | JP6002659B2 (enExample) |
| KR (1) | KR101958753B1 (enExample) |
| CN (2) | CN103154034B (enExample) |
| AU (1) | AU2011239706B2 (enExample) |
| BR (1) | BR112012026227A2 (enExample) |
| CA (1) | CA2796571C (enExample) |
| EA (2) | EA024701B1 (enExample) |
| ES (1) | ES2608475T3 (enExample) |
| IL (1) | IL222329B (enExample) |
| MX (1) | MX339621B (enExample) |
| NZ (2) | NZ623807A (enExample) |
| SG (1) | SG184310A1 (enExample) |
| WO (1) | WO2011130434A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018059465A1 (zh) * | 2016-09-29 | 2018-04-05 | 江苏恒瑞医药股份有限公司 | 抗cd27抗体、其抗原结合片段及其医药用途 |
| WO2019184935A1 (zh) * | 2018-03-28 | 2019-10-03 | 江苏恒瑞医药股份有限公司 | 抗cd27抗体、其抗原结合片段及其医药用途 |
Families Citing this family (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012026227A2 (pt) | 2010-04-13 | 2020-08-04 | Celldex Therapeutics, Inc. | anticorpo monoclonal humano ou humanizado, molécula biespecífica, vetor de expressão, célula transformada, composição, e, usos de um anticorpo |
| AU2011275749C1 (en) * | 2010-07-09 | 2015-09-17 | Aduro Biotech Holdings, Europe B.V. | Agonistic antibody to CD27 |
| CA2860170C (en) | 2010-12-22 | 2022-06-14 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists and antagonists of interleukin-2 |
| TWI679212B (zh) | 2011-11-15 | 2019-12-11 | 美商安進股份有限公司 | 針對bcma之e3以及cd3的結合分子 |
| MY175224A (en) * | 2012-03-15 | 2020-06-16 | Janssen Biotech Inc | Human anti-cd27 antibodies, methods, and uses |
| AU2013266215B2 (en) | 2012-05-25 | 2017-12-07 | Janssen Biotech, Inc. | Non-natural consensus albumin binding domains |
| WO2014140374A2 (en) * | 2013-03-15 | 2014-09-18 | Novo Nordisk A/S | Monovalent cd27 antibodies |
| EP3461493A1 (en) | 2013-03-29 | 2019-04-03 | Sumitomo Dainippon Pharma Co., Ltd. | Wt1 antigen peptide conjugate vaccine |
| US9725494B2 (en) | 2013-05-17 | 2017-08-08 | United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Soluble CD27 (sCD27) and the use thereof |
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