CN103154034B - 结合人cd27的抗体及其用途 - Google Patents

结合人cd27的抗体及其用途 Download PDF

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Publication number
CN103154034B
CN103154034B CN201180029048.XA CN201180029048A CN103154034B CN 103154034 B CN103154034 B CN 103154034B CN 201180029048 A CN201180029048 A CN 201180029048A CN 103154034 B CN103154034 B CN 103154034B
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antibody
seq
antibodies
cells
chain variable
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CN103154034A (zh
Inventor
T·凯勒
H·C·玛施
L·何
L·A·维泰尔
L·J·托马斯
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Celldex Therapeutics Inc
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Celldex Therapeutics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2317/565—Complementarity determining region [CDR]
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CN201180029048.XA 2010-04-13 2011-04-13 结合人cd27的抗体及其用途 Active CN103154034B (zh)

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US32372010P 2010-04-13 2010-04-13
US61/323,720 2010-04-13
US201161471459P 2011-04-04 2011-04-04
US61/471,459 2011-04-04
PCT/US2011/032355 WO2011130434A2 (en) 2010-04-13 2011-04-13 Antibodies that bind human cd27 and uses thereof

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ES2608475T3 (es) 2010-04-13 2017-04-11 Celldex Therapeutics, Inc. Anticuerpos que se unen a cd27 humana y usos de los mismos
AU2011275749C1 (en) * 2010-07-09 2015-09-17 Aduro Biotech Holdings, Europe B.V. Agonistic antibody to CD27
WO2012088446A1 (en) 2010-12-22 2012-06-28 Board Of Trustees Of The Leland Stanford Junior University Superagonists and antagonists of interleukin-2
TWI679212B (zh) 2011-11-15 2019-12-11 美商安進股份有限公司 針對ｂｃｍａ之e3以及ｃｄ３的結合分子
CA2867299C (en) 2012-03-15 2019-08-27 John Chen Human anti-cd27 antibodies, methods, and uses
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