CN105641037A

CN105641037A - Freshly-squeezed and spray-dried perilla leaf decoction powder and preparation technology thereof

Info

Publication number: CN105641037A
Application number: CN201610083514.7A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-11
Filing date: 2016-02-11
Publication date: 2016-06-08

Abstract

The invention discloses freshly-squeezed and spray-dried perilla leaf decoction powder and a preparation technology thereof. According to the technology, a perilla leaf medicinal material is selected, leached and squeezed while fresh after being harvested, and medicine juice is filtered out; medicine dregs are stirred with water, filtered and squeezed; obtained medicine juice is mixed and subjected to reduced pressure concentration and spray-drying; a condensate is obtained through reduced pressure concentration, volatile oil is separated and mixed with the spray-dried substance, and the mixture is sieved and bagged. The perilla leaf decoction powder prepared with the technology reserves effective ingredients in the medicinal material to the largest extent. The decoction powder is convenient to store, transport and prepare, controllable in quality and reliable in effect and has great significance in guaranteeing the clinical effect of traditional Chinese medicine. The popularization and application of the technology will have significant social and economic benefit.

Description

A kind of fresh squeezing spray-dried powders medicine materical crude slice of Su Ye and preparation technology thereof

Technical field

The invention belongs to Chinese medicinal materials manufacture field, particularly relate to the complete processing of Chinese medicine Su Ye medicine materical crude slice.

Background technology

Chinese medicine Su Ye is labiate purple perillaPerillafrutescens(L.) dry leave (or band spray) of Britt., gathers when summer, branches and leaves were luxuriant. It is loose cold that this product mainly has removing toxic substances, effect of relieving QI stagnancy in the stomach, for common cold caused by wind-cold, and evil of vomitting of coughing, vomiting of pregnancy, the treatment of the poisoning grade of fish soft-shelled turtle.

The processing mode of conventional Su Ye medicine materical crude slice is: after being gathered, dries in the shade or dries, packing storage and transport. These type of prepared slices of Chinese crude drugs, bulky, it is easy to pollute and go mouldy, quality is difficult to ensure, is unfavorable for that formula is adjusted and guarantees its clinical efficacy.

At present, particle medicine materical crude slice market also having Su Ye medicinal material to make after extracting is sold. Owing to, in particle medicine materical crude slice preparation process, extracting not only time consumption and energy consumption, and doing solvent because commonly using water, the nonpolar effective constituent in medicinal material is difficult to be extracted. In addition, the Su Ye medicinal material owing to extracting also is dry and passes through long-time storage, and therefore, the loss of effective constituent is also very big. In order to guarantee clinical effective, the steady quality of Su Ye medicinal material, a kind of novel Su Ye medicine materical crude slice and preparation technology thereof urgently develop.

Summary of the invention

The present invention discloses " a kind of fresh squeezing spray-dried powders medicine materical crude slice of Su Ye and preparation technology thereof ". This technique can retain the polarity in Su Ye medicinal material and nonpolar effective constituent to greatest extent, avoid the medicinal material loss of effective constituent that causes and decline of medical material quanlity in the processing of existing medicine materical crude slice and storage and transport process, reduce the pollution of medicinal material by mould etc., the steady quality and clinical safety guaranteeing Su Ye medicine materical crude slice is effectively had important meaning.

In order to realize above-mentioned purpose, the technical scheme of the present invention is:

After Su Ye gathers, cleaning, washing, takes advantage of fresh pressure extracting juice, and the dregs of a decoction add the water of 1 ~ 3 times amount, stirs 5 ~ 30min, plate-and-frame filter press press filtration, and extracting juice pressed again by the gained dregs of a decoction, merges concoction and filters with 80 ~ 200 eye mesh screens. By the liquid of gained, the relative density obtained is that the concentrated solution of 1.02 ~ 1.10 carries out spraying dry by 40 ~ 80 DEG C of concentrating under reduced pressure, and intake air temperature is 90 ~ 120 DEG C, and going out draught temperature is 70 ~ 100 DEG C. Collect spray dry product and pulverize. Collecting the Su Ye water of condensation of above-mentioned concentrating under reduced pressure gained, add the NaCl of 1% ~ 5% weight, be stirred to dissolve, solution is put in water-and-oil separator, places 12 ~ 48 hours under 4 DEG C ~ 10 DEG C environment, collects top oil reservoir, and toward wherein adding the anhydrous Na of 1% ~ 5% weight₂SO₄, after jolting 5 ~ 10min clock, less than 25 DEG C room temperatures are placed 1 ~ 6 hour, filter, obtain Soviet Union's leaf volatile oil. The volatile oil that this eliminates moisture mixes with Su Ye spray-drying powder, crosses 40 ~ 100 order sieves, vacuum packaging, the i.e. fresh squeezing spray-dried powders medicine materical crude slice of get Su Ye.

On the label of product packaging bags, the information such as the name of an article in printing, medicinal part, planting site, manufacturer, date manufactured, main component content, meridian distribution of property and flavor, function cure mainly, usage and dosage, toxic side effect and contraindication. TLC distinguish collection of illustrative plates and/or the high-efficient liquid phase character collection of illustrative plates of Su Ye is enclosed, as " identity card " of product in bag. In addition, in the packing bag of product, it is printed on Quick Response Code, can link, by scanning, information such as obtaining the former plant photo of product, medicinal material photo, medicine materical crude slice photo, proterties and microscopical identification feature.

The usefulness of the present invention is:

Fresh Su Ye medicinal material cleans direct squeezing, filtration, concentrating under reduced pressure, spraying dry, separation volatile oil, spray powder after washing and mixes with volatile oil, the powder decoction pieces obtained, it is possible to the effective constituent in complete reservation medicinal material to greatest extent. This kind of medicine materical crude slice volume compares to tradition medicine materical crude slice volume and reduces widely, and quality is more stable, is beneficial to accumulating and clinical adjustment, has very significant social effect and economic implications.

Embodiment

Embodiment 1

By the Su Ye medicinal material of fresh collection, clean, with water wash, take advantage of the squeezing of using fresh herb squeezing machine, get juice. The tap water of times amount that the gained dregs of a decoction add 2, stirs 20min, plate-and-frame filter press pressure extracting juice. The gained dregs of a decoction squeeze concoction with squeezing machine again. Being merged by above-mentioned 3 concoctions, concentrating under reduced pressure, temperature is set as 65 DEG C. When concentrated solution relative density is 1.05, spraying dry, intake air temperature is 110 DEG C, and going out draught temperature is 80 DEG C, collects dried object and pulverizes. In addition, the Su Ye water of condensation will collected during concentrating under reduced pressure, adds the NaCl of weight 5%, is stirred to dissolve. This solution is positioned in water-and-oil separator, and in 10 DEG C of environment, leaves standstill 24 hours, separated and collected upper strata volatile oil. The anhydrous Na of 2% weight is added in this volatile oil₂SO₄, after jolting 10min clock, less than 25 DEG C room temperatures place 6 hours, filter, obtain Soviet Union's leaf volatile oil. Being mixed with above-mentioned Su Ye spraying dry thing by this volatile oil, cross 60 order sieves, pack, 1kg/ bag, adds packed antioxidant and siccative, Vacuum Package, and labeling gets product.

Embodiment 2

By the Su Ye medicinal material of fresh collection, clean, with water wash, take advantage of the squeezing of using fresh herb squeezing machine, get juice. The tap water of times amount that the gained dregs of a decoction add 3, stirs 30min, plate-and-frame filter press pressure extracting juice. The gained dregs of a decoction squeeze concoction with squeezing machine again. Being merged by above-mentioned 3 concoctions, concentrating under reduced pressure, temperature is set as 60 DEG C. When concentrated solution relative density is 1.10, spraying dry, intake air temperature is 120 DEG C, and going out draught temperature is 90 DEG C, collects dried object and pulverizes. In addition, the Su Ye water of condensation will collected during concentrating under reduced pressure, adds the NaCl of weight 3%, is stirred to dissolve. This solution is positioned in water-and-oil separator, and in 10 DEG C of environment, leaves standstill 12 hours, separated and collected upper strata volatile oil. The anhydrous Na of 5% weight is added in this volatile oil₂SO₄, after jolting 5min clock, less than 25 DEG C room temperatures place 4 hours, filter, obtain Soviet Union's leaf volatile oil. Being mixed with above-mentioned Su Ye spraying dry thing by this volatile oil, cross 80 order sieves, pack, 1kg/ bag, adds packed antioxidant and siccative, Vacuum Package, and labeling gets product.

Above embodiment, is only the technological thought that this invention is described, can not limit the every technological thought proposed according to the present invention of protection scope of the present invention whereby, and any change done on technical scheme basis, all falls within the scope of protection of the invention.

Claims

1. the fresh squeezing spray-dried powders medicine materical crude slice of Su Ye and preparation technology thereof, it is characterized in that: after Su Ye gathers, clean, washing, takes advantage of fresh pressure extracting juice, and the dregs of a decoction add the water of 1 ~ 3 times amount, stir 5 ~ 30min, plate-and-frame filter press press filtration, extracting juice pressed again by the gained dregs of a decoction, merges concoction and filters with 80 ~ 200 eye mesh screens.

2. a kind of fresh squeezing spray-dried powders medicine materical crude slice of Su Ye according to claim 1 and preparation technology thereof, it is characterized in that: by the liquid of gained in claim 1,40 ~ 80 DEG C of concentrating under reduced pressure, gained relative density is the concentrated solution spraying dry of 1.02 ~ 1.10, intake air temperature is 90 ~ 120 DEG C, going out draught temperature is 70 ~ 100 DEG C, collects spray dry product and pulverizes.

3. a kind of fresh squeezing spray-dried powders medicine materical crude slice of Su Ye according to claim 1 and preparation technology thereof, it is characterized in that: the Su Ye water of condensation collecting the concentrating under reduced pressure gained in claim 2, add the NaCl of 1% ~ 5% weight, it is stirred to dissolve, solution is put in water-and-oil separator, place 12 ~ 48 hours under 4 DEG C ~ 10 DEG C environment, collect top oil reservoir, and toward wherein adding the anhydrous Na of 1% ~ 5% weight₂SO₄, after jolting 5 ~ 10min clock, less than 25 DEG C room temperatures are placed 1 ~ 6 hour, filter, obtain Soviet Union's leaf volatile oil, and itself and right are wanted the Su Ye spray-drying powder in 2 mix, and cross 40 ~ 100 order sieves, vacuum packaging, the i.e. fresh squeezing spray-dried powders medicine materical crude slice of get Su Ye.