CN107441261A - A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet - Google Patents
A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet Download PDFInfo
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- CN107441261A CN107441261A CN201710738964.XA CN201710738964A CN107441261A CN 107441261 A CN107441261 A CN 107441261A CN 201710738964 A CN201710738964 A CN 201710738964A CN 107441261 A CN107441261 A CN 107441261A
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- CN
- China
- Prior art keywords
- chinese violet
- crude slice
- materical crude
- medicine materical
- concoction
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet.The technique is cleaned, eluted after the harvesting of Chinese violet medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is spray-dried.Tokyo Violet Herb medicine materical crude slice prepared by this method, to greatest extent while remain polarity and nonpolar active ingredient in medicinal material.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine Chinese violet medicine materical crude slice.
Background technology
Chinese medicine Chinese violet is Violaceae Chinese violetViola yedoensis Makino drying herb.This
Sample bitter, acrid, cold；The thoughts of returning home, lung channel；With clearing heat and detoxicating, cool blood detumescence, the effect of clearing heat and promoting diuresis, furunculosis, carbuncle swells, scrofula are cured mainly
Scrofula, jaundice, dysentery, diarrhoea, hot eyes, larynx numbness, venomous snake bite.
The processing mode of conventional Chinese violet medicine materical crude slice is：Spring, the harvesting of season in autumn two, remove impurity, dry, directly packing storage
Hide and transport.These Chinese violet Hygienic Indexes dried can not be up to standard, and medicinal material easily occurs and goes mouldy, so as to cause medicinal material product
The decline of matter and the reduction of clinical efficacy.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily occur to go bad and contaminated, quality is difficult to protect
Card, it is unfavorable for conditioning agent formulation and ensures its clinical efficacy.
At present, in the market also has the manufactured granule pieces sale after extraction of Chinese violet medicinal material.Due to granule pieces
In preparation process, extraction not only time consumption and energy consumption, and also because conventional water does solvent, the nonpolar active ingredient in medicinal material is difficult to be carried
Take out.Further, since the Chinese violet medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient
Loss and it is very big.In order to ensure the clinic of Chinese violet medicinal material is effective, steady quality, a kind of new Chinese violet drink
Piece is urgently developed.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet ".This technique can be with
To greatest extent retain Chinese violet medicinal material in polarity and nonpolar active ingredient, avoid medicinal material existing medicine materical crude slice processing and
The decline of the loss of caused active ingredient and medical material quanlity in storage and transport process, pollution of the medicinal material by mould etc. is reduced, to ensuring
The steady quality and clinical safety of Chinese violet medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that：
Its herb is gathered in Chinese violet picking time, is cleaned, is cut into 1 ~ 2cm section, adds the water of 0.5 ~ 1 times of amount of medicinal material weight,
Stirring 15 ~ 30 minutes, fresh squeezing to be taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice,
The remaining dregs of a decoction add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction, 100 ~ 200 mesh sieve mistakes twice
Filter, obtains Chinese violet concoction.By the flower Chinese violet concoction of gained, be concentrated under reduced pressure in 40 ~ 80 DEG C, obtain relative density for 1.02 ~
1.10 concentrate.This concentrate is spray-dried, intake air temperature is set as 100 ~ 140 DEG C, air outlet temperature setting
For 90 ~ 120 DEG C.Collect dried object to be crushed, after crossing 60 ~ 100 mesh sieves, vacuum packaging, produce the fresh vacuum of squeezing of Chinese violet and do
Dry powder decoction pieces.
It is the name of an article in printing, medicinal part, planting site, manufacturer, the date of manufacture, main on the label of product packaging bags
The information such as component content, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Chinese violet is enclosed in bag
Thin layer differentiates collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, print
There is Quick Response Code, former plant photo, medicinal material photo, medicine materical crude slice photo, character and the micro- mirror for obtaining product can be linked by scanning
The information such as other feature.
The present invention is advantageous in that：
Fresh Chinese violet medicinal material directly squeezes after cleaning washing, filters, is concentrated under reduced pressure, being spray-dried, resulting powder drink
Piece, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume greatly subtracts compared to traditional medicine materical crude slice volume
Small, quality is more stable, beneficial to accumulating and clinical adjustment, has very significant social effect and economic implications.
Embodiment
Embodiment 1
By the Chinese violet medicinal material of fresh collection, clean, be cut into 1cm section, add the water of 0.5 times of amount of medicinal material weight, stirring 15
Minute, fresh squeezing is taken advantage of, collects and just squeezes concoction, the dregs of a decoction add the water of 5 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add
5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain Chinese violet concoction.Will
The flower Chinese violet concoction of gained is concentrated under reduced pressure, and temperature is set as 60 DEG C.When gained concentrate relative density is 1.03, spray is transferred to
Mist drying tower is spray-dried, and intake air temperature is set as 140 DEG C, and air outlet temperature is set as 110 DEG C, collects dried object,
Crush, cross 60 mesh sieves, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.
Embodiment 2
By the Chinese violet medicinal material of fresh collection, clean, be cut into 2cm section, add the water of 1 times of amount of medicinal material weight, stir 20 points
Clock, fresh squeezing is taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 3 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 4
Times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain Chinese violet concoction.Will
The flower Chinese violet concoction of gained is concentrated under reduced pressure, and temperature is set as 65 DEG C.When gained concentrate relative density is 1.05, spray is transferred to
Mist drying tower is spray-dried, and intake air temperature is set as 120 DEG C, and air outlet temperature is set as 90 DEG C, collects dried object, powder
It is broken, 80 mesh sieves are crossed, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
- A kind of 1. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet, it is characterised in that：In Chinese violet picking time Its herb is gathered, is cleaned, is cut into 1 ~ 2cm section, adds the water of 0.5 ~ 1 times of amount of medicinal material weight, stirs 15 ~ 30 minutes, takes advantage of fresh pressure Squeeze, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, and the remaining dregs of a decoction add 1 ~ 5 times The water of amount, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain Chinese violet concoction.
- 2. a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet according to claim 1, its feature exist In：By the Chinese violet concoction of gained in claim 1, it is concentrated under reduced pressure in 40 ~ 80 DEG C, obtains relative density as 1.02 ~ 1.10 Concentrate, it is spray-dried, intake air temperature is set as 100 ~ 140 DEG C, and air outlet temperature is set as 90 ~ 120 DEG C, Collect dried object to be crushed, after crossing 60 ~ 100 mesh sieves, aerosol container, produce the fresh squeezing spray-dried powders medicine materical crude slice of Chinese violet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710738964.XA CN107441261A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710738964.XA CN107441261A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107441261A true CN107441261A (en) | 2017-12-08 |
Family
ID=60493085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710738964.XA Pending CN107441261A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese violet |
Country Status (1)
| Country | Link |
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| CN (1) | CN107441261A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105287860A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower spray-dried powdery decoction piece and preparation technology thereof |
| CN105641013A (en) * | 2016-02-11 | 2016-06-08 | 徐自升 | Freshly-squeezed and spray-dried sweet wormwood decoction powder and preparation technology thereof |
| CN105641037A (en) * | 2016-02-11 | 2016-06-08 | 徐自升 | Freshly-squeezed and spray-dried perilla leaf decoction powder and preparation technology thereof |
| CN105663199A (en) * | 2016-02-11 | 2016-06-15 | 徐自升 | Freshly-squeezed folium artemisiae argyi spray drying granular medicinal slices and preparation technology thereof |
| CN105963349A (en) * | 2016-07-24 | 2016-09-28 | 徐漫 | Freshly squeezed barbed skullcap herb spray drying powder medicinal slices and preparing process thereof |
-
2017
- 2017-08-25 CN CN201710738964.XA patent/CN107441261A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105287860A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower spray-dried powdery decoction piece and preparation technology thereof |
| CN105641013A (en) * | 2016-02-11 | 2016-06-08 | 徐自升 | Freshly-squeezed and spray-dried sweet wormwood decoction powder and preparation technology thereof |
| CN105641037A (en) * | 2016-02-11 | 2016-06-08 | 徐自升 | Freshly-squeezed and spray-dried perilla leaf decoction powder and preparation technology thereof |
| CN105663199A (en) * | 2016-02-11 | 2016-06-15 | 徐自升 | Freshly-squeezed folium artemisiae argyi spray drying granular medicinal slices and preparation technology thereof |
| CN105963349A (en) * | 2016-07-24 | 2016-09-28 | 徐漫 | Freshly squeezed barbed skullcap herb spray drying powder medicinal slices and preparing process thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171208 |
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| WD01 | Invention patent application deemed withdrawn after publication |