CN107375402A - A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla - Google Patents
A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla Download PDFInfo
- Publication number
- CN107375402A CN107375402A CN201710738583.1A CN201710738583A CN107375402A CN 107375402 A CN107375402 A CN 107375402A CN 201710738583 A CN201710738583 A CN 201710738583A CN 107375402 A CN107375402 A CN 107375402A
- Authority
- CN
- China
- Prior art keywords
- gynostemma pentaphylla
- crude slice
- materical crude
- medicine materical
- squeezing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla.The technique is cleaned, eluted after Gynostemma pentaphyllum harvesting, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is spray-dried.Gynostemma pentaphylla powder decoction pieces prepared by this method, to greatest extent while remain polarity and nonpolar active ingredient in medicinal material.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese Medicine Jiaogulan medicine materical crude slice.
Background technology
Chinese Medicine Jiaogulan is Curcurbitaceae gynostemma pentaphyllaGynostemma pentaphyllum (Thunb.) Makino ground
Upper part.With QI invigorating, calm the nerves, hypotensive is clearing heat and detoxicating, the effect of cough-relieving apophlegmatic.
The processing mode of conventional gynostemma pentaphylla medicine materical crude slice is:Impurity is removed after harvesting, is dried, directly packing storage and transport.
These dry gynostemma pentaphylla Hygienic Indexes can not be up to standard, easily occur medicinal material go mouldy, so as to cause the decline of medical material quanlity and
The reduction of clinical efficacy.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily occur it is rotten and contaminated, quality it is difficult to ensure that, be unfavorable for adjusting
Agent prescription and ensure its clinical efficacy.
At present, in the market also has Gynostemma pentaphyllum manufactured granule pieces sale after extraction.Due to granule pieces system
During standby, extraction not only time consumption and energy consumption, and also because conventional water does solvent, the nonpolar active ingredient in medicinal material is difficult to be extracted
Out.Further, since the Gynostemma pentaphyllum of extraction is also to dry and by storage for a long time, therefore, the damage of active ingredient
Lose and very big.In order to ensure the clinic of Gynostemma pentaphyllum is effective, steady quality, a kind of new gynostemma pentaphylla medicine materical crude slice is urgently opened
Hair.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla ".This technique can be most
The polarity and the nonpolar active ingredient that retain in Gynostemma pentaphyllum of limits, avoid medicinal material from being processed and accumulating in existing medicine materical crude slice
During the loss of caused active ingredient and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, to ensuring strand
The steady quality and clinical safety of blue medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that:
Its aerial part is gathered in gynostemma pentaphylla picking time, is cleaned, is cut into the section of 1 ~ 2cm length, adds 0.5 ~ 1 times of amount of medicinal material weight
Water, stir 15 ~ 30 minutes, take advantage of fresh squeezing, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, and squeezing takes
Juice, the remaining dregs of a decoction add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction, 100 ~ 200 mesh twice
Filter is sieved through, obtains gynostemma pentaphylla concoction.By the flower Chinese violet concoction of gained, be concentrated under reduced pressure in 40 ~ 80 DEG C, obtain relative density for 1.02 ~
1.10 concentrate.This concentrate is spray-dried, intake air temperature is set as 100 ~ 140 DEG C, air outlet temperature setting
For 90 ~ 120 DEG C.Collect dried object to be crushed, after crossing 60 ~ 100 mesh sieves, vacuum packaging, produce fresh squeeze of gynostemma pentaphylla and be dried in vacuo
Powder decoction pieces.
It is the name of an article in printing, medicinal part, planting site, manufacturer, the date of manufacture, main on the label of product packaging bags
The information such as component content, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.The thin of gynostemma pentaphylla is enclosed in bag
Layer differentiates collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, it is printed on
Quick Response Code, former plant photo, medicinal material photo, medicine materical crude slice photo, character and the microscopical characters for obtaining product can be linked by scanning
The information such as feature.
The present invention is advantageous in that:
Fresh Gynostemma pentaphyllum directly squeezes after cleaning washing, filters, is concentrated under reduced pressure, being spray-dried, resulting powder decoction pieces,
The active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume greatly reduces compared to traditional medicine materical crude slice volume,
Quality is more stable, beneficial to accumulating and clinical adjustment, has very significant social effect and economic implications.
Embodiment
Embodiment 1
By the Gynostemma pentaphyllum of fresh collection, clean, be cut into 1cm section, add the water of 0.5 times of amount of medicinal material weight, stir 15 points
Clock, fresh squeezing is taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 5 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 5
Times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain gynostemma pentaphylla concoction.By institute
The flower Chinese violet concoction obtained is concentrated under reduced pressure, and temperature is set as 60 DEG C.When gained concentrate relative density is 1.03, spraying is transferred to
Drying tower is spray-dried, and intake air temperature is set as 140 DEG C, and air outlet temperature is set as 110 DEG C, collects dried object, powder
It is broken, 60 mesh sieves are crossed, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.
Embodiment 2
By the Gynostemma pentaphyllum of fresh collection, clean, be cut into 2cm section, add the water of 1 times of amount of medicinal material weight, stir 20 minutes,
Fresh squeezing is taken advantage of, collects and just squeezes concoction, the dregs of a decoction add the water of 3 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 4 times of amounts
Water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain gynostemma pentaphylla concoction.By gained
Flower Chinese violet concoction is concentrated under reduced pressure, and temperature is set as 65 DEG C.When gained concentrate relative density is 1.05, spray drying is transferred to
Tower is spray-dried, and intake air temperature is set as 120 DEG C, and air outlet temperature is set as 90 DEG C, collects dried object, crushes, mistake
80 mesh sieves, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
- A kind of 1. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla, it is characterised in that:Gathered in gynostemma pentaphylla picking time Its aerial part, clean, be cut into the section of 1 ~ 2cm length, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 minutes, take advantage of fresh Squeezing, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, and the remaining dregs of a decoction add 1 ~ 5 Times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain gynostemma pentaphylla concoction.
- A kind of 2. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla according to claim 1, it is characterised in that: By the gynostemma pentaphylla concoction of gained in claim 1, it is concentrated under reduced pressure in 40 ~ 80 DEG C, obtains the concentration that relative density is 1.02 ~ 1.10 Liquid, it is spray-dried, intake air temperature is set as 100 ~ 140 DEG C, and air outlet temperature is set as 90 ~ 120 DEG C, collects dry Dry thing is crushed, and after crossing 60 ~ 100 mesh sieves, aerosol container, produces the fresh squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710738583.1A CN107375402A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710738583.1A CN107375402A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107375402A true CN107375402A (en) | 2017-11-24 |
Family
ID=60346029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710738583.1A Pending CN107375402A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107375402A (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105213444A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Portulacae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
CN105213553A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
CN105213450A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Taraxaci fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
CN106109559A (en) * | 2016-07-23 | 2016-11-16 | 徐自升 | A kind of Flos Sophorae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
-
2017
- 2017-08-25 CN CN201710738583.1A patent/CN107375402A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105213444A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Portulacae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
CN105213553A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
CN105213450A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Taraxaci fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
CN106109559A (en) * | 2016-07-23 | 2016-11-16 | 徐自升 | A kind of Flos Sophorae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN107468751A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of Longtube Ground Ivy Herb | |
CN107050113A (en) | A kind of Flos Magnoliae Liliflorae is fresh to squeeze spray-dried powders medicine materical crude slice and its preparation technology | |
CN107714754A (en) | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of gynostemma pentaphylla | |
CN107362180A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of lycopodium calvatum | |
CN107375401A (en) | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of gynostemma pentaphylla | |
CN107375402A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gynostemma pentaphylla | |
CN107397787A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of Pogostemon cablin | |
CN107441154A (en) | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of Pogostemon cablin | |
CN107485638A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of lopseed | |
CN107375364A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of desmodium | |
CN107375565A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of pipewort | |
CN107485633A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of folium artemisiae argyi | |
CN107441131A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium | |
CN107375378A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of gerbera | |
CN107468727A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of ardisia japonica | |
CN107397783A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Canton love-pea vine | |
CN107441157A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Pogostemon cablin | |
CN107375351A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of phoenix-tail fern | |
CN107375541A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of field pennycress | |
CN107441233A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of black nightshade | |
CN107485640A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Herba Lycopi | |
CN107441381A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of lophatherum gracile | |
CN107375397A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of fringed pink | |
CN106109724A (en) | A kind of Herba Verbenae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof | |
CN107334789A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of scouring rush |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171124 |
|
WD01 | Invention patent application deemed withdrawn after publication |